The Oncosearch | Oncotarget

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Brenna M. Zimmer, Michelle E. Howell, Linlin Ma, Jeffrey R. Enders, Danielle Lehman, Eva Corey, Joseph J. Barycki, Melanie A. Simpson

Published Aug 19, 2021 · Vol. 12, No. 19 · pp. 1886-1902

Keywords: prostate cancer, castration resistance, detoxification, UDP-glucose dehydrogenase, patient-derived xenografts

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Zachary R. Wakefield, Mai Tanaka, Christine Pampo, Sharon Lepler, Lori Rice, Joy Guingab-Cagmat, Timothy J. Garrett, Dietmar W. Siemann

Published Aug 18, 2021 · Vol. 12, No. 18 · pp. 1737-1748

Keywords: aerobic exercise, breast cancer, hypoxia, doxorubicin, cardiotoxicity

Correlation between PD-L1 expression and MET gene amplification in patients with advanced non-small cell lung cancer and no other actionable oncogenic driver Research Paper

Marta Domènech, Ana M. Muñoz Marmol, Jose Luis Mate, Anna Estival, Teresa Moran, Marc Cucurull, Maria Saigi, Ainhoa Hernandez, Carolina Sanz, Alba Hernandez-Gallego, Aintzane Urbizu, Anna Martinez-Cardus, Adrià Bernat, Enric Carcereny

Published Aug 5, 2021 · Vol. 12, No. 18 · pp. 1802-1810

Keywords: non-small cell lung cancer, oncogenic driver, PD-L1, MET amplification, smoking habit

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Mario Scarpa, Shivani Kapoor, Eric S. Tvedte, Kshama A. Doshi, Ying S. Zou, Prerna Singh, Jonelle K. Lee, Aditi Chatterjee, Moaath K. Mustafa Ali, Robin E. Bromley, Julie C. Dunning Hotopp, Feyruz V. Rassool, Maria R. Baer

Published Aug 2, 2021 · Vol. 12, No. 18 · pp. 1763-1779

Keywords: FLT3 internal tandem duplication, Pim kinase, alternative non-homologous end-joining DNA repair, genomic instability, topoisomerase 2 inhibitors

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Taylor J. Chen, Wa Du, Jacob J. Junco, Cory Seth Bridges, Ye Shen, Monica Puppi, Karen R. Rabin, H. Daniel Lacorazza

Published Jul 31, 2021 · Vol. 12, No. 18 · pp. 1787-1801

Keywords: T-ALL, MAP2K7, 5z-7-oxozeaenol

Role of microRNAs in glioblastoma Review

Ming Chen, Zdravka Medarova, Anna Moore

Published Jul 30, 2021 · Vol. 12, No. 17 · pp. 1707-1723

Keywords: glioblastoma, microRNA, miRNA-based therapies, miRNA delivery

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Miguel Vizoso, Jacco van Rheenen

Published Jul 29, 2021 · Vol. 12, No. 17 · pp. 1651-1662

Keywords: targeted DNA methylation, CRISPR/Cas9-based system, IGFBP2, epithelial-to-mesenchymal transition

Exosomal and non-exosomal miRNA expression levels in patients with HCV-related cirrhosis and liver cancer Research Paper

Alisa A. Petkevich, Aleksandr A. Abramov, Vadim I. Pospelov, Natalya A. Malinina, Elena I. Kuhareva, Natalya V. Mazurchik, Olga I. Tarasova

Published Jul 29, 2021 · Vol. 12, No. 17 · pp. 1697-1706

Keywords: microvesicles, miRNA, cirrhosis, liver cancer, saliva

MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways Research Paper

Alice Augenlicht, Manuel Saiselet, Myriam Decaussin-Petrucci, Guy Andry, Jacques E. Dumont, Carine Maenhaut

Published Jul 17, 2021 · Vol. 12, No. 16 · pp. 1587-1599

Keywords: miRNA, papillary thyroid carcinoma, IRS2, MAPK, PI3K

High CD39 expression is associated with the non-muscle-invasive phenotype of human bladder cancer Research Paper

Janaina Mendes Ferreira, Luiz Henrique Gomes Matheus, Renato Vasconcelos Souza de Almeida, Petronio Augusto de Souza Melo, Kátia Ramos Moreira Leite, Claudio Bovolenta Murta, Joaquim Francisco de Almeida Claro, Cleber Pinto Camacho, José Pontes-Júnior, Humberto Dellê

Published Jul 16, 2021 · Vol. 12, No. 16 · pp. 1580-1586

Keywords: bladder cancer, purinergic signaling, ectonucleotidases, CD39

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Subarna Ghosh, Priyanka Dey Talukdar, Abhinandan Bhattacharjee, Sarbani Giri, Nitai Pada Bhattacharyya, Urmi Chatterji

Published Jul 2, 2021 · Vol. 12, No. 15 · pp. 1520-1539

Keywords: arecoline, tight junction, head and neck cancer, lncRNA-NEAT1, JunD

Hypofractionation: less is more? Research Perspective

Neethu Billy Graham Mariam, Yee Pei Song, Nuradh Joseph, Peter Hoskin, Kimberley Reeves, Nuria Porta, Nicholas James, Ananya Choudhury

Published Jun 29, 2021 · Vol. 12, No. 17 · pp. 1729-1733

Keywords: hypofractionation, BC2001, BCON, bladder cancer

Prokineticin-1 induces normal lymphangiogenic activity and is involved in lymphangiogenesis and lymph node metastasis in colorectal cancer Research Paper

Takayuki Naruse, Takanori Goi, Akio Yamaguchi

Published Jun 23, 2021 · Vol. 12, No. 14 · pp. 1388-1397

Keywords: prokineticin-1, lymphangiogenic activity, colorectal cancer

The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Marina Simón, Jesper Tranekjær Jørgensen, Karina Juhl, Andreas Kjaer

Published Jun 22, 2021 · Vol. 12, No. 14 · pp. 1366-1376

Keywords: photothermal therapy (PTT), indocyanine green (ICG), urokinase plasminogen activator receptor (uPAR), cancer, hyperthermia

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Kassidy A. Hebert, Sergio Jaramillo, Wangjie Yu, Min Wang, Ratna Veeramachaneni, Vlad C. Sandulache, Andrew G. Sikora, Mark D. Bonnen, Ananth V. Annapragada, David Corry, Farrah Kheradmand, Raj K. Pandita, Michelle S. Ludwig, Tej K. Pandita, Shixia Huang, Cristian Coarfa, Sandra L. Grimm, Dimuthu Perera, George Miles, Yohannes T. Ghebre

Published Jun 19, 2021 · Vol. 12, No. 14 · pp. 1339-1353

Keywords: esomeprazole, proton pump inhibitors, ionizing radiation, radiosensitization, tumor control

Correction: Transforming growth factor β-induced epithelial-to-mesenchymal signature predicts metastasis-free survival in non-small cell lung cancer Correction

Edna Gordian, Eric A. Welsh, Nicholas Gimbrone, Erin M. Siegel, David Shibata, Ben C. Creelan, William Douglas Cress, Steven A. Eschrich, Eric B. Haura, Teresita Muñoz-Antonia

Published Jun 18, 2021 · Vol. 12, No. 13 · pp. 1325-1325

MRI texture features from tumor core and margin in the prediction of response to neoadjuvant chemotherapy in patients with locally advanced breast cancer Research Paper

Christopher Kolios, Lakshmanan Sannachi, Archya Dasgupta, Harini Suraweera, Daniel DiCenzo, Gregory Stanisz, Arjun Sahgal, Frances Wright, Nicole Look-Hong, Belinda Curpen, Ali Sadeghi-Naini, Maureen Trudeau, Sonal Gandhi, Michael C. Kolios, Gregory J. Czarnota

Published Jun 16, 2021 · Vol. 12, No. 14 · pp. 1354-1365

Keywords: radiomics, MRI, breast cancer, neoadjuvant chemotherapy, biomarkers

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Maura Argenziano, Chiara Tortora, Alessandra Di Paola, Elvira Pota, Martina Di Martino, Daniela Di Pinto, Caterina Di Leva, Francesca Rossi

Published Jun 16, 2021 · Vol. 12, No. 14 · pp. 1377-1387

Keywords: acute monocytic leukemia, eltrombopag, deferasirox, iron chelation, cancer

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Catherine T. Haring, Chandan Bhambhani, Collin Brummel, Brittany Jewell, Emily Bellile, Molly E. Heft Neal, Erin Sandford, Ryan M. Spengler, Apurva Bhangale, Matthew E. Spector, Jonathan McHugh, Mark E. Prince, Michelle Mierzwa, Francis P. Worden, Muneesh Tewari, Paul L. Swiecicki, J. Chad Brenner

Published Jun 11, 2021 · Vol. 12, No. 13 · pp. 1214-1229

Keywords: HPV, head and neck cancer, oropharyngeal cancer, ctDNA, circulating tumor DNA

Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy Review

Annachiara Mollace, Maria Laura Coluccio, Giuseppe Donato, Vincenzo Mollace, Natalia Malara

Published Jun 9, 2021 · Vol. 12, No. 13 · pp. 1281-1295

Keywords: RAGE, AGEs, colon cancer, microenvironment, Warburg effect

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Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Correlation between PD-L1 expression and MET gene amplification in patients with advanced non-small cell lung cancer and no other actionable oncogenic driver Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Role of microRNAs in glioblastoma Review

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Exosomal and non-exosomal miRNA expression levels in patients with HCV-related cirrhosis and liver cancer Research Paper

MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways Research Paper

High CD39 expression is associated with the non-muscle-invasive phenotype of human bladder cancer Research Paper

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Hypofractionation: less is more? Research Perspective

Prokineticin-1 induces normal lymphangiogenic activity and is involved in lymphangiogenesis and lymph node metastasis in colorectal cancer Research Paper

The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Correction: Transforming growth factor β-induced epithelial-to-mesenchymal signature predicts metastasis-free survival in non-small cell lung cancer Correction

MRI texture features from tumor core and margin in the prediction of response to neoadjuvant chemotherapy in patients with locally advanced breast cancer Research Paper

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Correlation between PD-L1 expression and MET gene amplification in patients with advanced non-small cell lung cancer and no other actionable oncogenic driver Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Role of microRNAs in glioblastoma Review

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Exosomal and non-exosomal miRNA expression levels in patients with HCV-related cirrhosis and liver cancer Research Paper

MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways Research Paper

High CD39 expression is associated with the non-muscle-invasive phenotype of human bladder cancer Research Paper

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Hypofractionation: less is more? Research Perspective

Prokineticin-1 induces normal lymphangiogenic activity and is involved in lymphangiogenesis and lymph node metastasis in colorectal cancer Research Paper

The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Correction: Transforming growth factor β-induced epithelial-to-mesenchymal signature predicts metastasis-free survival in non-small cell lung cancer Correction

MRI texture features from tumor core and margin in the prediction of response to neoadjuvant chemotherapy in patients with locally advanced breast cancer Research Paper

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy Review