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Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma Research Paper

Christos Demosthenous, Jing Jing Han, Mary J. Stenson, Matthew J. Maurer, Linda E. Wellik, Brian Link, Kristen Hege, Ahmet Dogan, Eduardo Sotomayor, Thomas Witzig, Mamta Gupta

Published Mar 20, 2015 · Vol. 6, No. 11 · pp. 9488-9501

Heterogeneous chromosome 12p deletion is an independent adverse prognostic factor and resistant to bortezomib-based therapy in multiple myeloma Research Paper

Fei Li, Yan Xu, Ping Deng, Ye Yang, Weiwei Sui, Fengyan Jin, Mu Hao, Zengjun Li, Meirong Zang, Dehui Zhou, Zhimin Gu, Kun Ru, Jianxiang Wang, Tao Cheng, Lugui Qiu

Published Mar 20, 2015 · Vol. 6, No. 11 · pp. 9434-9444

Gut bacteria require neutrophils to promote mammary tumorigenesis Research Paper

Jessica R. Lakritz, Theofilos Poutahidis, Sheyla Mirabal, Bernard J. Varian, Tatiana Levkovich, Yassin M. Ibrahim, Jerrold M. Ward, Ellen C. Teng, Brett Fisher, Nicola Parry, Stephanie Lesage, Natalie Alberg, Sravya Gourishetti, James G. Fox, Zhongming Ge, Susan E. Erdman

Published Mar 20, 2015 · Vol. 6, No. 11 · pp. 9387-9396

Rampant centrosome amplification underlies more aggressive disease course of triple negative breast cancers Research Paper

Vaishali Pannu, Karuna Mittal, Guilherme Cantuaria, Michelle D. Reid, Xiaoxian Li, Shashikiran Donthamsetty, Michelle McBride, Sergey Klimov, Remus Osan, Meenakshi V. Gupta, Padmashree C.G. Rida, Ritu Aneja

Published Mar 19, 2015 · Vol. 6, No. 12 · pp. 10487-10497

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation Clinical Research Papers

Andreas D. Ã˜rskov, Marianne B. Treppendahl, Anni Skovbo, Mette S. Holm, Lone S. Friis, Marianne Hokland, Kirsten GrÃ¸nbÃ¦k

Published Mar 18, 2015 · Vol. 6, No. 11 · pp. 9612-9626

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer Research Paper

Yi-Nan Liu, Tzu-Hua Chang, Meng-Feng Tsai, Shang-Gin Wu, Tzu-Hsiu Tsai, Hsuan-Yu Chen, Sung-Liang Yu, James Chih-Hsin Yang, Jin-Yuan Shih

Published Mar 18, 2015 · Vol. 6, No. 12 · pp. 10415-10431

Netrin-4 as a biomarker promotes cell proliferation and invasion in gastric cancer Research Paper

Bin Lv, Chunhua Song, Lijun Wu, Qi Zhang, Daisen Hou, Ping Chen, Shunji Yu, Zhicheng Wang, Yiwei Chu, Jun Zhang, Dongqin Yang, Jie Liu

Published Mar 18, 2015 · Vol. 6, No. 12 · pp. 9794-9806

Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion Research Paper

SÃ©verine Roselli, Jay Pundavela, Yohann Demont, Sam Faulkner, Sheridan Keene, John Attia, Chen Chen Jiang, Xu Dong Zhang, Marjorie M. Walker, Hubert Hondermarck

Published Mar 18, 2015 · Vol. 6, No. 12 · pp. 10473-10486

Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib Research Paper

Shengzhi Xie, Yongwu Li, Xiaoyan Li, Linxiong Wang, Na Yang, Yadi Wang, Huafeng Wei

Published Mar 16, 2015 · Vol. 6, No. 11 · pp. 9206-9219

PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors Research Paper

Annalisa Lonetti, Alessandra Cappellini, Antonino Maria SpartÃ, Francesca Chiarini, Francesca Buontempo, Camilla Evangelisti, Cecilia Evangelisti, Ester Orsini, James A. McCubrey, Alberto Maria Martelli

Published Mar 16, 2015 · Vol. 6, No. 12 · pp. 10399-10414

Tyrosine-protein phosphatase non-receptor type 12 expression is a good prognostic factor in resectable non-small cell lung cancer Clinical Research Papers

Xun Cao, Yan-Zhen Chen, Ruo-Zhen Luo, Lin Zhang, Song-Liang Zhang, Jun Zeng, Yu-Chuan Jiang, Yu-Jing Han, Zhe-Sheng Wen

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11704-11713

Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment Research Paper

Laura BrohÃ©e, StÃ©phane Demine, JÃ©rome Willems, Thierry Arnould, Alain C. Colige, Christophe F. Deroanne

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11264-11280

Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer Research Paper

Anm Nazmul H. Khan, Nonna Kolomeyevskaya, Kelly L. Singel, Melissa J. Grimm, Kirsten B. Moysich, Sayeema Daudi, Kassondra S. Grzankowski, Sashikant Lele, Lourdes Ylagan, Gill A. Webster, Scott I. Abrams, Kunle Odunsi, Brahm H. Segal

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11310-11326

Low thyroid hormone levels improve survival in murine model for ocular melanoma Research Paper

Ido Didi Fabian, Mordechai Rosner, Ina Fabian, Vicktoria Vishnevskia-Dai, Ofira Zloto, Elena Shinderman Maman, Keren Cohen, Martin Ellis, Hung-Yun Lin, Aleck Hercbergs, Paul J. Davis, Osnat Ashur-Fabian

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11038-11046

Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis Research Paper

Evgeniy Stoyanov, Guy Ludwig, Lina Mizrahi, Devorah Olam, Temima Schnitzer-Perlman, Elena Tasika, Gabriele Sass, Gisa Tiegs, Yong Jiang, Ting Nie, James Kohler, Raymond F. Schinazi, Paula M. Vertino, Howard Cedar, Eithan Galun, Daniel Goldenberg

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11047-11060

Expression of programmed cell death ligand 1 (PD-L1) and prevalence of tumor-infiltrating lymphocytes (TILs) in chordoma Research Paper

Yong Feng, Jacson Shen, Yan Gao, Yunfei Liao, Gregory Cote, Edwin Choy, Ivan Chebib, Henry Mankin, Francis Hornicek, Zhenfeng Duan

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11139-11149

Synaptopodin-2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration Research Paper

FuiBoon Kai, James P. Fawcett, Roy Duncan

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11162-11174

Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin Research Paper

Lahiru Gangoda, Shivakumar Keerthikumar, Pamali Fonseka, Laura E. Edgington, Ching-Seng Ang, Cemil Ozcitti, Matthew Bogyo, Belinda S. Parker, Suresh Mathivanan

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11175-11190

Low spinophilin expression enhances aggressive biological behavior of breast cancer Research Paper

Daniela Schwarzenbacher, Verena Stiegelbauer, Alexander Deutsch, Anna Lena Ress, Ariane Aigelsreiter, Silvia Schauer, Karin Wagner, Tanja Langsenlehner, Margit Resel, Armin Gerger, Hui Ling, Cristina Ivan, George Adrian Calin, Gerald Hoefler, Beate Rinner, Martin Pichler

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11191-11202

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma Research Paper

Anna Granata, Roberta Nicoletti, Paola Perego, Egidio Iorio, Balaji Krishnamachary, Fabio Benigni, Alessandro Ricci, Franca Podo, Zaver M. Bhujwalla, Silvana Canevari, Marina Bagnoli, Delia Mezzanzanica

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11216-11230

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Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma Research Paper

Heterogeneous chromosome 12p deletion is an independent adverse prognostic factor and resistant to bortezomib-based therapy in multiple myeloma Research Paper

Gut bacteria require neutrophils to promote mammary tumorigenesis Research Paper

Rampant centrosome amplification underlies more aggressive disease course of triple negative breast cancers Research Paper

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation Clinical Research Papers

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer Research Paper

Netrin-4 as a biomarker promotes cell proliferation and invasion in gastric cancer Research Paper

Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion Research Paper

Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib Research Paper

PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors Research Paper

Tyrosine-protein phosphatase non-receptor type 12 expression is a good prognostic factor in resectable non-small cell lung cancer Clinical Research Papers

Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment Research Paper

Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer Research Paper

Low thyroid hormone levels improve survival in murine model for ocular melanoma Research Paper

Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis Research Paper

Expression of programmed cell death ligand 1 (PD-L1) and prevalence of tumor-infiltrating lymphocytes (TILs) in chordoma Research Paper

Synaptopodin-2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration Research Paper

Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin Research Paper

Low spinophilin expression enhances aggressive biological behavior of breast cancer Research Paper

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma Research Paper

Heterogeneous chromosome 12p deletion is an independent adverse prognostic factor and resistant to bortezomib-based therapy in multiple myeloma Research Paper

Gut bacteria require neutrophils to promote mammary tumorigenesis Research Paper

Rampant centrosome amplification underlies more aggressive disease course of triple negative breast cancers Research Paper

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation Clinical Research Papers

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer Research Paper

Netrin-4 as a biomarker promotes cell proliferation and invasion in gastric cancer Research Paper

Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion Research Paper

Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib Research Paper

PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors Research Paper

Tyrosine-protein phosphatase non-receptor type 12 expression is a good prognostic factor in resectable non-small cell lung cancer Clinical Research Papers

Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment Research Paper

Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer Research Paper

Low thyroid hormone levels improve survival in murine model for ocular melanoma Research Paper

Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis Research Paper

Expression of programmed cell death ligand 1 (PD-L1) and prevalence of tumor-infiltrating lymphocytes (TILs) in chordoma Research Paper

Synaptopodin-2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration Research Paper

Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin Research Paper

Low spinophilin expression enhances aggressive biological behavior of breast cancer Research Paper

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma Research Paper