The Oncosearch | Oncotarget

Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers Research Paper

Milan Radovich, Patrick J. Kiel, Stacy M. Nance, Erin E. Niland, Megan E. Parsley, Meagan E. Ferguson, Guanglong Jiang, Natraj R. Ammakkanavar, Lawrence H. Einhorn, Liang Cheng, Mehdi Nassiri, Darrell D. Davidson, Daniel A. Rushing, Patrick J. Loehrer, Roberto Pili, Nasser Hanna, J. Thomas Callaghan, Todd C. Skaar, Paul R. Helft, Safi Shahda, Bert H. Oâ€™Neil, Bryan P. Schneider

Published Jul 15, 2016 · Vol. 7, No. 35 · pp. 56491-56500

Troponin-I enhances and is required for oncogenic overgrowth Priority Research Paper

Sergio Casas-TintÃ³, Antonio Maraver, Manuel Serrano, Alberto FerrÃºs

Published Jul 15, 2016 · Vol. 7, No. 33 · pp. 52631-52642

Ultraconserved long non-coding RNA uc.63 in breast cancer Research Paper

Alberto Marini, Anna Maria Lena, Emanuele Panatta, Cristina Ivan, Leng Han, Han Liang, Margherita Annicchiarico-Petruzzelli, Nicola Di Daniele, George A. Calin, Eleonora Candi, Gerry Melino

Published Jul 13, 2016 · Vol. 8, No. 22 · pp. 35669-35680

Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway Research Paper

Liang Wang, Zhenxian Zhao, Weidong Feng, Zhijun Ye, Weigang Dai, Changhua Zhang, Jianjun Peng, Kaiming Wu

Published Jul 13, 2016 · Vol. 7, No. 32 · pp. 51713-51719

Panels of tumor-derived RNA markers in peripheral blood of patients with non-small cell lung cancer: their dependence on age, gender and clinical stages Research Paper

Chih-Feng Chian, Yi-Ting Hwang, Harn-Jing Terng, Shih-Chun Lee, Tsui-Yi Chao, Hung Chang, Ching-Liang Ho, Yi-Ying Wu, Wann-Cherng Perng

Published Jul 13, 2016 · Vol. 7, No. 31 · pp. 50582-50595

Overexpression of mutant EGFR protein indicates a better survival benefit from EGFR-TKI therapy in non-small cell lung cancer Research Paper

Yun Ling, Xin Yang, Wenbin Li, Zhuo Li, Lin Yang, Tian Qiu, Lei Guo, Lin Dong, Lin Li, Jianming Ying, Dongmei Lin

Published Jul 13, 2016 · Vol. 7, No. 33 · pp. 52862-52869

Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Ai N.H. Phan, Tuyen N.M. Hua, Min-Kyu Kim, Vu T.A. Vo, Jong-Whan Choi, Hyun-Won Kim, Jin Kyung Rho, Ki Woo Kim, Yangsik Jeong

Published Jul 13, 2016 · Vol. 7, No. 34 · pp. 54702-54713

Incidence and origin of histologically confirmed liver metastases: an explorative case-study of 23,154 patients Research Paper

Jannemarie de Ridder, Johannes H.W. de Wilt, Femke Simmer, Lucy Overbeek, Valery Lemmens, Iris Nagtegaal

Published Jul 13, 2016 · Vol. 7, No. 34 · pp. 55368-55376

Responses to crizotinib in patients with ALK-positive lung adenocarcinoma who tested immunohistochemistry (IHC)-positive and fluorescence in situ hybridization (FISH)-negative Clinical Research Papers

Di Ma, Zheng Wang, Lin Yang, Xinlin Mu, Yan Wang, Xinming Zhao, Junling Li, Dongmei Lin

Published Jul 13, 2016 · Vol. 7, No. 39 · pp. 64410-64420

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype Research Paper

Fan Zhang, Hongsheng Wang, Xianfeng Wang, Guanmin Jiang, Hao Liu, Ge Zhang, Hao Wang, Rui Fang, Xianzhang Bu, Shaohui Cai, Jun Du

Published Jul 13, 2016 · Vol. 7, No. 32 · pp. 52294-52306

Specific patterns of PIWI-interacting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma Research Paper

Francesca Rizzo, Antonio Rinaldi, Giovanna Marchese, Elena Coviello, Assunta Sellitto, Angela Cordella, Giorgio Giurato, Giovanni Nassa, Maria Ravo, Roberta Tarallo, Luciano Milanesi, Anna Destro, Guido Torzilli, Massimo Roncalli, Luca Di Tommaso, Alessandro Weisz

Published Jul 13, 2016 · Vol. 7, No. 34 · pp. 54650-54661

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress Research Paper

Hiroshi Saijo, Yoshihiko Hirohashi, Toshihiko Torigoe, Ryota Horibe, Akari Takaya, Aiko Murai, Terufumi Kubo, Toshimitsu Kajiwara, Tsutomu Tanaka, Yosuke Shionoya, Eri Yamamoto, Reo Maruyama, Munehide Nakatsugawa, Takayuki Kanaseki, Tomohide Tsukahara, Yasuaki Tamura, Yasushi Sasaki, Takashi Tokino, Hiromu Suzuki, Toru Kondo, Hiroki Takahashi, Noriyuki Sato

Published Jul 13, 2016 · Vol. 7, No. 31 · pp. 50043-50056

MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment Research Paper

Pier Paolo Leoncini, Alice Bertaina, Dimitrios Papaioannou, Christian Flotho, Riccardo Masetti, Silvia Bresolin, Giuseppe Menna, Nicola Santoro, Marco Zecca, Giuseppe Basso, Giovanni Nigita, Dario Veneziano, Sara Pagotto, Katia Dâ€™Ovidio, Rossella Rota, Adrienne Dorrance, Carlo M. Croce, Charlotte Niemeyer, Franco Locatelli, Ramiro Garzon

Published Jul 13, 2016 · Vol. 7, No. 34 · pp. 55395-55408

CD44v6-competent tumor exosomes promote motility, invasion and cancer-initiating cell marker expression in pancreatic and colorectal cancer cells Research Paper

Zhe Wang, Anja von Au, Martina SchnÃ¶lzer, Thilo Hackert, Margot ZÃ¶ller

Published Jul 13, 2016 · Vol. 7, No. 34 · pp. 55409-55436

An appraisal of drug development timelines in the Era of precision oncology Research Paper

Denis Leonardo Jardim, Maria Schwaederle, David S. Hong, Razelle Kurzrock

Published Jul 13, 2016 · Vol. 7, No. 33 · pp. 53037-53046

LncRNAs in pancreatic cancer Review

Xiaoyi Huang, Xiaosong Zhi, Yisha Gao, Na Ta, Hui Jiang, Jianming Zheng

Published Jul 12, 2016 · Vol. 7, No. 35 · pp. 57379-57390

Somatic mutations predict outcomes of hypomethylating therapy in patients with myelodysplastic syndrome Research Paper

Seung-Hyun Jung, Yoo-Jin Kim, Seon-Hee Yim, Hye-Jung Kim, Yong-Rim Kwon, Eun-Hye Hur, Bon-Kwan Goo, Yun-Suk Choi, Sug Hyung Lee, Yeun-Jun Chung, Je-Hwan Lee

Published Jul 11, 2016 · Vol. 7, No. 34 · pp. 55264-55275

CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer Research Paper

Rony K. Roy, Michal M. Hoppe, Supriya Srivastava, Animesh Samanta, Neel Sharma, Kar Tong Tan, Henry Yang, Dominic C. Voon, Brendan Pang, Ming Teh, Naoko Murata-Kamiya, Masanori Hatakeyama, Young-Tae Chang, Wei Peng Yong, Yoshiaki Ito, Khek Yu Ho, Patrick Tan, Richie Soong, Phillip H. Koeffler, Khay Guan Yeoh, Anand D. Jeyasekharan

Published Jul 11, 2016 · Vol. 7, No. 34 · pp. 55290-55301

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies Research Paper

Lara Paracchini, Laura Mannarino, Ilaria Craparotta, Chiara Romualdi, Robert Fruscio, Tommaso Grassi, Vittoria Fotia, Giulia Caratti, Patrizia Perego, Enrica Calura, Luca Clivio, Maurizio D’Incalci, Luca Beltrame, Sergio Marchini

Published Jul 9, 2016 · Vol. 12, No. 24 · pp. 2404-2417

Keywords: ovarian cancer, temporal heterogeneity, spatial heterogeneity, targeted next generation sequencing, drug resistance

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer Research Paper

Hui Pan, Tao Jiang, Ningning Cheng, Qi Wang, Shengxiang Ren, Xuefei Li, Chao Zhao, Limin Zhang, Weijing Cai, Caicun Zhou

Published Jul 9, 2016 · Vol. 7, No. 31 · pp. 49948-49960

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Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers Research Paper

Troponin-I enhances and is required for oncogenic overgrowth Priority Research Paper

Ultraconserved long non-coding RNA uc.63 in breast cancer Research Paper

Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway Research Paper

Panels of tumor-derived RNA markers in peripheral blood of patients with non-small cell lung cancer: their dependence on age, gender and clinical stages Research Paper

Overexpression of mutant EGFR protein indicates a better survival benefit from EGFR-TKI therapy in non-small cell lung cancer Research Paper

Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Incidence and origin of histologically confirmed liver metastases: an explorative case-study of 23,154 patients Research Paper

Responses to crizotinib in patients with ALK-positive lung adenocarcinoma who tested immunohistochemistry (IHC)-positive and fluorescence in situ hybridization (FISH)-negative Clinical Research Papers

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype Research Paper

Specific patterns of PIWI-interacting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma Research Paper

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress Research Paper

MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment Research Paper

CD44v6-competent tumor exosomes promote motility, invasion and cancer-initiating cell marker expression in pancreatic and colorectal cancer cells Research Paper

An appraisal of drug development timelines in the Era of precision oncology Research Paper

LncRNAs in pancreatic cancer Review

Somatic mutations predict outcomes of hypomethylating therapy in patients with myelodysplastic syndrome Research Paper

CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer Research Paper

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies Research Paper

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers Research Paper

Troponin-I enhances and is required for oncogenic overgrowth Priority Research Paper

Ultraconserved long non-coding RNA uc.63 in breast cancer Research Paper

Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway Research Paper

Panels of tumor-derived RNA markers in peripheral blood of patients with non-small cell lung cancer: their dependence on age, gender and clinical stages Research Paper

Overexpression of mutant EGFR protein indicates a better survival benefit from EGFR-TKI therapy in non-small cell lung cancer Research Paper

Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Incidence and origin of histologically confirmed liver metastases: an explorative case-study of 23,154 patients Research Paper

Responses to crizotinib in patients with ALK-positive lung adenocarcinoma who tested immunohistochemistry (IHC)-positive and fluorescence in situ hybridization (FISH)-negative Clinical Research Papers

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype Research Paper

Specific patterns of PIWI-interacting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma Research Paper

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress Research Paper

MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment Research Paper

CD44v6-competent tumor exosomes promote motility, invasion and cancer-initiating cell marker expression in pancreatic and colorectal cancer cells Research Paper

An appraisal of drug development timelines in the Era of precision oncology Research Paper

LncRNAs in pancreatic cancer Review

Somatic mutations predict outcomes of hypomethylating therapy in patients with myelodysplastic syndrome Research Paper

CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer Research Paper

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies Research Paper

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer Research Paper