The Oncosearch | Oncotarget

Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment Research Paper

Ailin Guo, Pin Lu, Greg Coffey, Pamela Conley, Anjali Pandey, Y. Lynn Wang

Published Jan 10, 2017 · Vol. 8, No. 8 · pp. 12953-12967

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells Research Paper

Renate Wagner, Gerald StÃ¼biger, Daniel Veigel, Michael Wuczkowski, Peter Lanzerstorfer, Julian Weghuber, Emmanouil Karteris, Karin Nowikovsky, Nastasia Wilfinger-Lutz, Christian F. Singer, RamÃ³n Colomer, Bellinda BenhamÃº, MarÃa Luz LÃ³pez-RodrÃguez, Peter Valent, Thomas W. Grunt

Published Jan 10, 2017 · Vol. 8, No. 7 · pp. 11600-11613

The heterogeneous landscape of ALK negative ALCL Review

Elisabetta Mereu, Elisa Pellegrino, Irene ScarfÃ², Giorgio Inghirami, Roberto Piva

Published Jan 4, 2017 · Vol. 8, No. 11 · pp. 18525-18536

Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer Research Paper

Cristina Segovia, MÃ³nica MartÃnez-FernÃ¡ndez, Marta DueÃ±as, Carolina Rubio, Fernando F. LÃ³pez-CalderÃ³n, Clotilde Costa, Cristina Saiz-Ladera, MarÃa FernÃ¡ndez-Grajera, JosÃ© Duarte, Huberto GarcÃa MuÃ±oz, Federico de la Rosa, Felipe Villacampa, Daniel Castellano, JesÃºs M. Paramio

Published Jan 2, 2017 · Vol. 8, No. 6 · pp. 10531-10542

Influence of EGFR mutational status on metastatic behavior in non squamous non small cell lung cancer Research Paper

Alessandro Russo, Tindara Franchina, Giuseppina Rosaria Rita Ricciardi, Caterina Fanizza, Antonino Scimone, Giuseppe Chiofalo, Antonio Giordano, Vincenzo Adamo

Published Jan 2, 2017 · Vol. 8, No. 5 · pp. 8717-8725

AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis Research Paper

Abhishek A. Singh, Amit Mandoli, Koen H.M. Prange, Marko Laakso, Joost H.A. Martens

Published Dec 24, 2016 · Vol. 8, No. 8 · pp. 12855-12865

Unveiling changes in the landscape of patient populations in cancer early drug development Review

Cinta Hierro, AnalÃa Azaro, Guillem ArgilÃ©s, Elena Elez, Patricia GÃ³mez, Joan Carles, Jordi Rodon

Published Nov 9, 2016 · Vol. 8, No. 8 · pp. 14158-14172

Is ovarian cancer a targetable disease? A systematic review and meta-analysis and genomic data investigation Research Paper

Nicoletta Staropoli, Domenico Ciliberto, Silvia Chiellino, Francesca Caglioti, Teresa Del Giudice, Simona Gualtieri, Angela Salvino, Alessandra Strangio, Cirino Botta, Sandro Pignata, Pierfrancesco Tassone, Pierosandro Tagliaferri

Published Oct 13, 2016 · Vol. 7, No. 50 · pp. 82741-82756

Tyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functions Review

Adriana Borriello, Ilaria Caldarelli, Debora Bencivenga, Emanuela Stampone, Silverio Perrotta, Adriana Oliva, Fulvio Della Ragione

Published Oct 13, 2016 · Vol. 8, No. 3 · pp. 5540-5565

Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

Kei Kawaguchi, Takashi Murakami, Bartosz Chmielowski, Kentaro Igarashi, Tasuku Kiyuna, Michiaki Unno, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Fritz C. Eilber, Robert M. Hoffman

Published Sep 28, 2016 · Vol. 7, No. 44 · pp. 71737-71743

miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone Research Paper

Jian-Bo Fan, Jian-Wei Ruan, Wei Liu, Lun-Qing Zhu, Xin-Hui Zhu, Hong Yi, Sheng-Yu Cui, Jian-Ning Zhao, Zhi-Ming Cui

Published Sep 20, 2016 · Vol. 7, No. 43 · pp. 70613-70622

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice Research Paper

Nicholas H. Farina, Areg Zingiryan, Jacqueline A. Akech, Cody J. Callahan, Huimin Lu, Janet L. Stein, Lucia R. Languino, Gary S. Stein, Jane B. Lian

Published Sep 13, 2016 · Vol. 7, No. 43 · pp. 70462-70474

Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations Research Paper

Jean-FranÃ§ois Spinella, Pauline Cassart, Chantal Richer, Virginie Saillour, Manon Ouimet, Sylvie Langlois, Pascal St-Onge, Thomas Sontag, Jasmine Healy, Mark D. Minden, Daniel Sinnett

Published Sep 1, 2016 · Vol. 7, No. 40 · pp. 65485-65503

GBM-associated mutations and altered protein expression are more common in young patients Research Paper

Sherise D. Ferguson, Joanne Xiu, Shiao-Pei Weathers, Shouhao Zhou, Santosh Kesari, Stephanie E. Weiss, Roeland G. Verhaak, Raymond J. Hohl, Geoffrey R. Barger, Sandeep K. Reddy, Amy B. Heimberger

Published Aug 25, 2016 · Vol. 7, No. 43 · pp. 69466-69478

Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation Research Paper

Hilmar Quentmeier, Claudia Pommerenke, Ole Ammerpohl, Robert Geffers, Vivien Hauer, Roderick AF MacLeod, Stefan Nagel, Julia Romani, Emanuela Rosati, Anders RosÃ©n, Cord C Uphoff, Margarete Zaborski, Hans G Drexler

Published Aug 23, 2016 · Vol. 7, No. 39 · pp. 63456-63465

Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways Research Paper

Pamela Ovadje, Saleem Ammar, Jose-Antonio Guerrero, John Thor Arnason, Siyaram Pandey

Published Aug 22, 2016 · Vol. 7, No. 45 · pp. 73080-73100

Prolyl hydroxylase 2 (PHD2) inhibition protects human renal epithelial cells and mice kidney from hypoxia injury Research Paper

Yi Fang, Hui Zhang, Yihong Zhong, Xiaoqiang Ding

Published Aug 5, 2016 · Vol. 7, No. 34 · pp. 54317-54328

PATZ1 expression correlates positively with BAX and negatively with BCL6 and survival in human diffuse large B cell lymphomas Research Paper

Renato Franco, GiosuÃ¨ Scognamiglio, Elena Valentino, Michela Vitiello, Antonio Luciano, Giuseppe Palma, Claudio Arra, Elvira La Mantia, Luigi Panico, Valentina Tenneriello, Antonello Pinto, Ferdinando Frigeri, Gaetana Capobianco, Gerardo Botti, Laura Cerchia, Annarosaria De Chiara, Monica Fedele

Published Aug 1, 2016 · Vol. 7, No. 37 · pp. 59158-59172

NETs: organ-related epigenetic derangements and potential clinical applications Review

Mauro Cives, Valeria Simone, Francesca Maria Rizzo, Franco Silvestris

Published Jul 13, 2016 · Vol. 7, No. 35 · pp. 57414-57429

Independent evaluation of a FOXM1-based quantitative malignancy diagnostic system (qMIDS) on head and neck squamous cell carcinomas Research Paper

Hong Ma, Haiyan Dai, Xiaofeng Duan, Zhenglong Tang, Rui Liu, Kunjun Sun, Ke Zhou, Hao Chen, Hang Xiang, Jinsheng Wang, Qiong Gao, Yuan Zou, Hong Wan, Muy-Teck Teh

Published Jul 9, 2016 · Vol. 7, No. 34 · pp. 54555-54563

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Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment Research Paper

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells Research Paper

The heterogeneous landscape of ALK negative ALCL Review

Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer Research Paper

Influence of EGFR mutational status on metastatic behavior in non squamous non small cell lung cancer Research Paper

AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis Research Paper

Unveiling changes in the landscape of patient populations in cancer early drug development Review

Is ovarian cancer a targetable disease? A systematic review and meta-analysis and genomic data investigation Research Paper

Tyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functions Review

Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone Research Paper

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice Research Paper

Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations Research Paper

GBM-associated mutations and altered protein expression are more common in young patients Research Paper

Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation Research Paper

Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways Research Paper

Prolyl hydroxylase 2 (PHD2) inhibition protects human renal epithelial cells and mice kidney from hypoxia injury Research Paper

PATZ1 expression correlates positively with BAX and negatively with BCL6 and survival in human diffuse large B cell lymphomas Research Paper

NETs: organ-related epigenetic derangements and potential clinical applications Review

Independent evaluation of a FOXM1-based quantitative malignancy diagnostic system (qMIDS) on head and neck squamous cell carcinomas Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment Research Paper

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells Research Paper

The heterogeneous landscape of ALK negative ALCL Review

Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer Research Paper

Influence of EGFR mutational status on metastatic behavior in non squamous non small cell lung cancer Research Paper

AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis Research Paper

Unveiling changes in the landscape of patient populations in cancer early drug development Review

Is ovarian cancer a targetable disease? A systematic review and meta-analysis and genomic data investigation Research Paper

Tyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functions Review

Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone Research Paper

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice Research Paper

Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations Research Paper

GBM-associated mutations and altered protein expression are more common in young patients Research Paper

Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation Research Paper

Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways Research Paper

Prolyl hydroxylase 2 (PHD2) inhibition protects human renal epithelial cells and mice kidney from hypoxia injury Research Paper

PATZ1 expression correlates positively with BAX and negatively with BCL6 and survival in human diffuse large B cell lymphomas Research Paper

NETs: organ-related epigenetic derangements and potential clinical applications Review

Independent evaluation of a FOXM1-based quantitative malignancy diagnostic system (qMIDS) on head and neck squamous cell carcinomas Research Paper