The Oncosearch | Oncotarget

RHAMM splice variants confer radiosensitivity in human breast cancer cell lines Research Paper

Alexandra SchÃ¼tze, Christian Vogeley, Tobias Gorges, SÃ¶ren Twarock, Jonas Butschan, Anna Babayan, Diana Klein, Shirley K. Knauer, Eric Metzen, Volkmar MÃ¼ller, Verena Jendrossek, Klaus Pantel, Karin Milde-Langosch, Jens W. Fischer, Katharina RÃ¶ck

Published Feb 8, 2016 · Vol. 7, No. 16 · pp. 21428-21440

Beyond evidence-based data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma Review

Lorena Incorvaia, Giuseppe Bronte, Viviana Bazan, Giuseppe Badalamenti, Sergio Rizzo, Gianni Pantuso, Clara Natoli, Antonio Russo

Published Feb 8, 2016 · Vol. 7, No. 16 · pp. 21259-21271

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition Research Paper

Srikumar M. Raja, Swapnil S. Desale, Bhopal Mohapatra, Haitao Luan, Kruti Soni, Jinjin Zhang, Matthew A. Storck, Dan Feng, Timothy A. Bielecki, Vimla Band, Samuel M. Cohen, Tatiana K. Bronich, Hamid Band

Published Feb 7, 2016 · Vol. 7, No. 9 · pp. 10522-10535

Targeting hypoxic response for cancer therapy Review

Elisa Paolicchi, Federica Gemignani, Marija Krstic-Demonacos, Shoukat Dedhar, Luciano Mutti, Stefano Landi

Published Feb 7, 2016 · Vol. 7, No. 12 · pp. 13464-13478

Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation Priority Research Paper

Angela C. Hirbe, Sonika Dahiya, Dinorah Friedmann-Morvinski, Inder M. Verma, D. Wade Clapp, David H. Gutmann

Published Feb 7, 2016 · Vol. 7, No. 7 · pp. 7403-7414

Activation of the PD-1/PD-L1 immune checkpoint confers tumor cell chemoresistance associated with increased metastasis Research Paper

Madison Black, Ivraym B. Barsoum, Peter Truesdell, Tiziana Cotechini, Shannyn K. Macdonald-Goodfellow, Margaret Petroff, D. Robert Siemens, Madhuri Koti, Andrew W.B. Craig, Charles H. Graham

Published Feb 7, 2016 · Vol. 7, No. 9 · pp. 10557-10567

Role of heme oxygenase-1 in the pathogenesis and tumorigenicity of Kaposiâ€™s sarcoma-associated herpesvirus Research Paper

Lu Dai, Jing Qiao, David Nguyen, Amanda P. Struckhoff, Lisa Doyle, Karlie Bonstaff, Luis Del Valle, Chris Parsons, Bryan P. Toole, Rolf Renne, Zhiqiang Qin

Published Feb 7, 2016 · Vol. 7, No. 9 · pp. 10459-10471

The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met Research Paper

Ashley J. Williamson, Michelle E. Doscas, Jin Ye, Katherine B. Heiden, Mingzhao Xing, Yi Li, Richard A. Prinz, Xiulong Xu

Published Feb 7, 2016 · Vol. 7, No. 9 · pp. 10472-10485

Quantification of Unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples Research Paper

Raquel Buj, Izaskun Mallona, Anna DÃez-Villanueva, VÃctor Barrera, DÃdac Mauricio, Manel Puig-Domingo, Jordi L. Reverter, Xavier Matias-Guiu, Daniel Azuara, Jose L. RamÃrez, Sergio Alonso, Rafael Rosell, Gabriel CapellÃ, Manuel Perucho, Mercedes Robledo, Miguel A. Peinado, Mireia JordÃ

Published Feb 7, 2016 · Vol. 7, No. 9 · pp. 10536-10546

OLA1 contributes to epithelial-mesenchymal transition in lung cancer by modulating the GSK3Î²/snail/E-cadherin signaling Research Paper

Li Bai, Zubin Yu, Jiawei Zhang, Shuai Yuan, Chen Liao, Prince V.S. Jeyabal, Valentina Rubio, Huarong Chen, Yafei Li, Zheng-Zheng Shi

Published Feb 6, 2016 · Vol. 7, No. 9 · pp. 10402-10413

Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology Research Paper

James Che, Victor Yu, Manjima Dhar, Corinne Renier, Melissa Matsumoto, Kyra Heirich, Edward B. Garon, Jonathan Goldman, Jianyu Rao, George W. Sledge, Mark D. Pegram, Shruti Sheth, Stefanie S. Jeffrey, Rajan P. Kulkarni, Elodie Sollier, Dino Di Carlo

Published Feb 6, 2016 · Vol. 7, No. 11 · pp. 12748-12760

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3 Research Paper

Eva A. Ebbing, Jan Paul Medema, Helene Damhofer, Sybren L. Meijer, Kausilia K. Krishnadath, Mark I. van Berge Henegouwen, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven

Published Feb 5, 2016 · Vol. 7, No. 9 · pp. 10243-10254

Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines Research Paper

Brian Koss, Jeremy Ryan, Amit Budhraja, Katherine Szarama, Xue Yang, Madhavi Bathina, Michael H. Cardone, Zaneta Nikolovska-Coleska, Anthony Letai, Joseph T. Opferman

Published Feb 5, 2016 · Vol. 7, No. 10 · pp. 11500-11511

Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cells Research Paper

Elena Alexandrova, Giovanni Nassa, Giacomo Corleone, Anton Buzdin, Alexander M. Aliper, Nadezhda Terekhanova, Denis Shepelin, Alexander Zhavoronkov, Michael Tamm, Luciano Milanesi, Nicola Miglino, Alessandro Weisz, Pieter Borger

Published Feb 5, 2016 · Vol. 7, No. 18 · pp. 25150-25161

Regression/Eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide Research Paper

Charles C. Cates, Angelo D. Arias, Lynn S. Nakayama Wong, Michael W. LamÃ©, Maxim Sidorov, Geraldine Cayanan, Douglas J. Rowland, Jennifer Fung, Georg Karpel-Massler, Markus D. Siegelin, Lloyd A. Greene, James M. Angelastro

Published Feb 5, 2016 · Vol. 7, No. 11 · pp. 12718-12730

Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer Research Paper

Jana Jezkova, Jason S. Williams, Filipe Pinto, Stephen J. Sammut, Geraint T. Williams, Simon Gollins, Ramsay J. McFarlane, Rui Manuel Reis, Jane A. Wakeman

Published Feb 5, 2016 · Vol. 7, No. 10 · pp. 11478-11486

Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system Research Paper

Maki Morishita, Tomoki Muramatsu, Yumiko Suto, Momoki Hirai, Teruaki Konishi, Shin Hayashi, Daichi Shigemizu, Tatsuhiko Tsunoda, Keiji Moriyama, Johji Inazawa

Published Feb 4, 2016 · Vol. 7, No. 9 · pp. 10182-10192

Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC Research Paper

Marco Scarpa, Melania Scarpa, Ignazio Castagliuolo, Francesca Erroi, Andromachi Kotsafti, Silvia Basato, Paola Brun, Renata Dâ€™IncÃ, Massimo Rugge, Imerio Angriman, Carlo Castoro

Published Feb 4, 2016 · Vol. 7, No. 9 · pp. 10322-10331

The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients Research Paper

Shang-Gin Wu, Yi-Nan Liu, Meng-Feng Tsai, Yih-Leong Chang, Chong-Jen Yu, Pan-Chyr Yang, James Chih-Hsin Yang, Yueh-Feng Wen, Jin-Yuan Shih

Published Feb 4, 2016 · Vol. 7, No. 11 · pp. 12404-12413

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression Research Paper

Chiara Ciardiello, Maria Serena Roca, Alessia Noto, Francesca Bruzzese, Tania Moccia, Carlo Vitagliano, Elena Di Gennaro, Gennaro Ciliberto, Giuseppe Roscilli, Luigi Aurisicchio, Emanuele Marra, Rita Mancini, Alfredo Budillon, Alessandra Leone

Published Feb 4, 2016 · Vol. 7, No. 15 · pp. 19559-19574

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RHAMM splice variants confer radiosensitivity in human breast cancer cell lines Research Paper

Beyond evidence-based data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma Review

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition Research Paper

Targeting hypoxic response for cancer therapy Review

Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation Priority Research Paper

Activation of the PD-1/PD-L1 immune checkpoint confers tumor cell chemoresistance associated with increased metastasis Research Paper

Role of heme oxygenase-1 in the pathogenesis and tumorigenicity of Kaposiâ€™s sarcoma-associated herpesvirus Research Paper

The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met Research Paper

Quantification of Unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples Research Paper

OLA1 contributes to epithelial-mesenchymal transition in lung cancer by modulating the GSK3Î²/snail/E-cadherin signaling Research Paper

Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology Research Paper

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3 Research Paper

Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines Research Paper

Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cells Research Paper

Regression/Eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide Research Paper

Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer Research Paper

Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system Research Paper

Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC Research Paper

The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients Research Paper

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

RHAMM splice variants confer radiosensitivity in human breast cancer cell lines Research Paper

Beyond evidence-based data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma Review

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition Research Paper

Targeting hypoxic response for cancer therapy Review

Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation Priority Research Paper

Activation of the PD-1/PD-L1 immune checkpoint confers tumor cell chemoresistance associated with increased metastasis Research Paper

Role of heme oxygenase-1 in the pathogenesis and tumorigenicity of Kaposiâ€™s sarcoma-associated herpesvirus Research Paper

The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met Research Paper

Quantification of Unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples Research Paper

OLA1 contributes to epithelial-mesenchymal transition in lung cancer by modulating the GSK3Î²/snail/E-cadherin signaling Research Paper

Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology Research Paper

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3 Research Paper

Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines Research Paper

Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cells Research Paper

Regression/Eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide Research Paper

Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer Research Paper

Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system Research Paper

Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC Research Paper

The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients Research Paper

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression Research Paper