The Oncosearch | Oncotarget

The BET-bromodomain inhibitor JQ1 renders neuroblastoma cells more resistant to NK cell-mediated recognition and killing by downregulating ligands for NKG2D and DNAM-1 receptors Research Paper

Irene Veneziani, Doriana Fruci, Mirco Compagnone, Vito Pistoia, Paolo Rossi, Loredana Cifaldi

Published Mar 15, 2019 · Vol. 10, No. 22 · pp. 2151-2160

Regulation of KrÃ¼ppel-Like Factor 4 (KLF4) expression through the transcription factor Yin-Yang 1 (YY1) in non-Hodgkin B-cell lymphoma Research Paper

Mario Morales-Martinez, Alberto Valencia-Hipolito, Gabriel G. Vega, Natividad Neri, Maria J. Nambo, Isabel Alvarado, Ivonne Cuadra, Marco A. Duran-Padilla, Otoniel Martinez-Maza, Sara Huerta-Yepez, Mario I. Vega

Published Mar 15, 2019 · Vol. 10, No. 22 · pp. 2173-2188

Molecular mechanisms and pathobiology of oncogenic fusion transcripts in epithelial tumors Review

Musaffe Tuna, Christopher I. Amos, Gordon B. Mills

Published Mar 12, 2019 · Vol. 10, No. 21 · pp. 2095-2111

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple negative breast cancer Research Paper

Marie-Anne Goyette, Rebecca Cusseddu, Islam Elkholi, Afnan Abu-Thuraia, Nehme El-Hachem, Benjamin Haibe-Kains, Jean-Philippe Gratton, Jean-François Côté

Published Mar 12, 2019 · Vol. 10, No. 21 · pp. 2055-2067

Keywords: triple-negative breast cancer, drug repurposing, AXL, phenothiazines, metastasis

CD164 regulates proliferation, progression, and invasion of human glioblastoma cells Research Paper

Chung-Ching Wang, Dueng-Yuan Hueng, Ai-Fang Huang, Wei-Liang Chen, Shih-Ming Huang, James Yi-Hsin Chan

Published Mar 12, 2019 · Vol. 10, No. 21 · pp. 2041-2054

Keywords: CD164, human glioma, glioblastoma, autophagy

Specific allelic variants of SNPs in the MDM2 and MDMX genes are associated with earlier tumor onset and progression in Caucasian breast cancer patients Research Paper

Marcus Bauer, Eva Johanna Kantelhardt, Thorsten Stiewe, Andrea Nist, Marco Mernberger, Katharina Politt, Volker Hanf, Tilmann Lantzsch, Christoph Uleer, Susanne Peschel, Jutta John, JÃ¶rg Buchmann, Edith Weigert, Karl-Friedrich BÃ¼rrig, Claudia Wickenhauser, Christoph Thomssen, Frank Bartel, Martina Vetter

Published Mar 8, 2019 · Vol. 10, No. 20 · pp. 1975-1992

DICER1 somatic mutations strongly impair miRNA processing even in benign thyroid lesions Research Paper

Anello Marcello Poma, Vincenzo Condello, Maria Denaro, Liborio Torregrossa, Rossella Elisei, Paolo Vitti, Fulvio Basolo

Published Mar 5, 2019 · Vol. 10, No. 19 · pp. 1785-1797

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development Priority Research Paper

Yafang Li, Xiangjun Xiao, Yohan Bossé, Olga Gorlova, Ivan Gorlov, Younghun Han, Jinyoung Byun, Natasha Leighl, Jakob S. Johansen, Matt Barnett, Chu Chen, Gary Goodman, Angela Cox, Fiona Taylor, Penella Woll, H.-Erich Wichmann, Judith Manz, Thomas Muley, Angela Risch, Albert Rosenberger, Jiali Han, Katherine Siminovitch, Susanne M. Arnold, Eric B. Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M. Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J. Duell, Lesley M. Butler, Richard Houlston, María Soler Artigas, Kjell Grankvist, Mikael Johansson, Frances A. Shepherd, Michael W. Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C. Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Geoffrey Liu, Stig E. Liu, Xifeng Wu, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C. Aldrich, William S. Bush, Adonina Tardon, Gad Rennert, M. Dawn Teare, John K. Field, Lambertus A. Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B. Schabath, Angeline S. Andrew, Pier Alberto Bertazzi, Angela C. Pesatori, David C. Christiani, Neil Caporaso, Mattias Johansson, James D. McKay, Paul Brennan, Rayjean J. Hung, Christopher I. Amos

Published Mar 5, 2019 · Vol. 10, No. 19 · pp. 1760-1774

Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced NRAS- or BRAF-mutated melanoma Research Paper

Carla M.L. van Herpen, Sanjiv S. Agarwala, Axel Hauschild, Carola Berking, J. Thaddeus Beck, Dirk Schadendorf, Rob Jansen, Paola Queirolo, Paolo A. Ascierto, Christian U. Blank, Michael C. Heinrich, Rupam R. Pal, Adnan Derti, Victor Antona, Heidi Nauwelaerts, Angela Zubel, Reinhard Dummer

Published Mar 5, 2019 · Vol. 10, No. 19 · pp. 1850-1859

Discovery of lipid biomarkers correlated with disease progression in clear cell renal cell carcinoma using desorption electrospray ionization imaging mass spectrometry Research Paper

Keita Tamura, Makoto Horikawa, Shumpei Sato, Hideaki Miyake, Mitsutoshi Setou

Published Mar 1, 2019 · Vol. 10, No. 18 · pp. 1688-1703

Statins affect human glioblastoma and other cancers through TGF-β inhibition Research Paper

Aizhen Xiao, Breanna Brenneman, Desiree Floyd, Laurey Comeau, Kelsey Spurio, Inan Olmez, Jeongwu Lee, Ichiro Nakano, Jakub Godlewski, Agnieszka Bronisz, Noritaka Kagaya, Kazuo Shin-ya, Benjamin Purow

Published Mar 1, 2019 · Vol. 10, No. 18 · pp. 1716-1728

Tumor suppressor RARRES1 links tubulin deglutamylation to mitochondrial metabolism and cell survival Priority Research Paper

Sara Maimouni, Mi-Hye Lee, You-Me Sung, Michael Hall, Arpita Roy, Chokri Ouaari, Yoo-Seok Hwang, Justin Spivak, Eric Glasgow, Matthew Swift, Jay Patel, Amrita Cheema, Deepak Kumar, Stephen Byers

Published Feb 26, 2019 · Vol. 10, No. 17 · pp. 1606-1624

Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes Research Paper

Bernat Navarro-Serer, Eva P. Childers, Nicole M. Hermance, Dayna Mercadante, Amity L. Manning

Published Feb 26, 2019 · Vol. 10, No. 17 · pp. 1649-1659

The molecular landscape of adult diffuse gliomas and relevance to clinical trials Editorial

Patrick J. Cimino, Eric C. Holland

Published Feb 22, 2019 · Vol. 10, No. 19 · pp. 1758-1759

Super-enhancers: novel target for pancreatic ductal adenocarcinoma Research Paper

Chandrayee Ghosh, Santanu Paul, Prasad Dandawate, Sumedha S. Gunewardena, Dharmalingam Subramaniam, Cameron West, Shrikant Anant, Animesh Dhar

Published Feb 22, 2019 · Vol. 10, No. 16 · pp. 1554-1571

mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development Research Paper

Laura Molina, Hong Yang, Adeola O. Adebayo Michael, Michael Oertel, Aaron Bell, Sucha Singh, Xin Chen, Junyan Tao, Satdarshan P.S. Monga

Published Feb 19, 2019 · Vol. 10, No. 15 · pp. 1475-1490

TGF-Î² inducible epithelial-to-mesenchymal transition in renal cell carcinoma Research Paper

Sandy Tretbar, Peter Krausbeck, Anja MÃ¼ller, Michael Friedrich, Christoforos Vaxevanis, Juergen Bukur, Simon Jasinski-Bergner, Barbara Seliger

Published Feb 19, 2019 · Vol. 10, No. 15 · pp. 1507-1524

CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition Research Paper

Jasmin B. Post, Nizar Hami, Alexander E.E. Mertens, Suraya Elfrink, Johannes L. Bos, Hugo J.G. Snippert

Published Feb 15, 2019 · Vol. 10, No. 14 · pp. 1440-1457

Global gene expression of histologically normal primary skin cells from BCNS subjects reveals "single-hit" effects that are influenced by rapamycin Research Paper

Amruta Phatak, Mohammad Athar, James A. Crowell, David Leffel, Brittney-Shea Herbert, Allen E. Bale, Levy Kopelovich

Published Feb 15, 2019 · Vol. 10, No. 14 · pp. 1360-1387

Application of cell-free DNA for genomic tumor profiling: a feasibility study Research Paper

Lise B. Ahlborn, Kristoffer S. Rohrberg, Migle Gabrielaite, Ida V. Tuxen, Christina W. Yde, Iben Spanggaard, Eric Santoni-Rugiu, Finn C. Nielsen, Ulrik Lassen, Morten Mau-Sorensen, Olga Ã˜strup

Published Feb 15, 2019 · Vol. 10, No. 14 · pp. 1388-1398

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The BET-bromodomain inhibitor JQ1 renders neuroblastoma cells more resistant to NK cell-mediated recognition and killing by downregulating ligands for NKG2D and DNAM-1 receptors Research Paper

Regulation of KrÃ¼ppel-Like Factor 4 (KLF4) expression through the transcription factor Yin-Yang 1 (YY1) in non-Hodgkin B-cell lymphoma Research Paper

Molecular mechanisms and pathobiology of oncogenic fusion transcripts in epithelial tumors Review

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple negative breast cancer Research Paper

CD164 regulates proliferation, progression, and invasion of human glioblastoma cells Research Paper

Specific allelic variants of SNPs in the MDM2 and MDMX genes are associated with earlier tumor onset and progression in Caucasian breast cancer patients Research Paper

DICER1 somatic mutations strongly impair miRNA processing even in benign thyroid lesions Research Paper

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development Priority Research Paper

Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced NRAS- or BRAF-mutated melanoma Research Paper

Discovery of lipid biomarkers correlated with disease progression in clear cell renal cell carcinoma using desorption electrospray ionization imaging mass spectrometry Research Paper

Statins affect human glioblastoma and other cancers through TGF-β inhibition Research Paper

Tumor suppressor RARRES1 links tubulin deglutamylation to mitochondrial metabolism and cell survival Priority Research Paper

Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes Research Paper

The molecular landscape of adult diffuse gliomas and relevance to clinical trials Editorial

Super-enhancers: novel target for pancreatic ductal adenocarcinoma Research Paper

mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development Research Paper

TGF-Î² inducible epithelial-to-mesenchymal transition in renal cell carcinoma Research Paper

CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition Research Paper

Global gene expression of histologically normal primary skin cells from BCNS subjects reveals "single-hit" effects that are influenced by rapamycin Research Paper

Application of cell-free DNA for genomic tumor profiling: a feasibility study Research Paper

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European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The BET-bromodomain inhibitor JQ1 renders neuroblastoma cells more resistant to NK cell-mediated recognition and killing by downregulating ligands for NKG2D and DNAM-1 receptors Research Paper

Regulation of KrÃ¼ppel-Like Factor 4 (KLF4) expression through the transcription factor Yin-Yang 1 (YY1) in non-Hodgkin B-cell lymphoma Research Paper

Molecular mechanisms and pathobiology of oncogenic fusion transcripts in epithelial tumors Review

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple negative breast cancer Research Paper

CD164 regulates proliferation, progression, and invasion of human glioblastoma cells Research Paper

Specific allelic variants of SNPs in the MDM2 and MDMX genes are associated with earlier tumor onset and progression in Caucasian breast cancer patients Research Paper

DICER1 somatic mutations strongly impair miRNA processing even in benign thyroid lesions Research Paper

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development Priority Research Paper

Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced NRAS- or BRAF-mutated melanoma Research Paper

Discovery of lipid biomarkers correlated with disease progression in clear cell renal cell carcinoma using desorption electrospray ionization imaging mass spectrometry Research Paper

Statins affect human glioblastoma and other cancers through TGF-β inhibition Research Paper

Tumor suppressor RARRES1 links tubulin deglutamylation to mitochondrial metabolism and cell survival Priority Research Paper

Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes Research Paper

The molecular landscape of adult diffuse gliomas and relevance to clinical trials Editorial

Super-enhancers: novel target for pancreatic ductal adenocarcinoma Research Paper

mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development Research Paper

TGF-Î² inducible epithelial-to-mesenchymal transition in renal cell carcinoma Research Paper

CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition Research Paper

Global gene expression of histologically normal primary skin cells from BCNS subjects reveals "single-hit" effects that are influenced by rapamycin Research Paper

Application of cell-free DNA for genomic tumor profiling: a feasibility study Research Paper