The Oncosearch | Oncotarget

Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models Research Paper

Kei Kawaguchi, Qinghong Han, Shukuan Li, Yuying Tan, Kentaro Igarashi, Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Bartosz Bartosz, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Arun S. Singh, Mark A. Eckardt, Michiaki Unno, Fritz C. Eilber, Robert M. Hoffman

Published Jan 17, 2018 · Vol. 9, No. 13 · pp. 11119-11125

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models Research Paper

Kei Kawaguchi, Kentaro Igarashi, Shukuan Li, Qinghong Han, Yuying Tan, Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Takashi Murakami, Bartosz Chmielowski, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li5, Michiaki Unno, Fritz C. Eilber, Robert M. Hoffman

Published Dec 12, 2017 · Vol. 9, No. 1 · pp. 915-923

Progesterone inhibits contraction and increases TREK-1 potassium channel expression in late pregnant rat uterus Research Paper

Zongzhi Yin, Yun Li, Wenzhu He, Dan Li, Hongyan Li, Yuanyuan Yang, Bing Shen, Xi Wang, Yunxia Cao, Raouf A. Khalil

Published Dec 7, 2017 · Vol. 9, No. 1 · pp. 651-661

S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells Research Paper

Yan Wang, ZhongSheng Sun, Moshe Szyf

Published Dec 5, 2017 · Vol. 8, No. 67 · pp. 111866-111881

S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting MicroRNA 34a/b-methionine adenosyltransferase 2A/2B axis Research Paper

Maria Lauda Tomasi, Carla Cossu, Ylenia Spissu, Andrea Floris, Minjung Ryoo, Ainhoa Iglesias-Ara, Qiang Wang, Stephen J. Pandol, Neil A. Bhowmick, Ekihiro Seki, Edwin M. Posadas, Shelly C. Lu

Published Aug 12, 2017 · Vol. 8, No. 45 · pp. 78851-78869

Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

Kei Kawaguchi, Kentaro Igarashi, Shukuan Li, Qinghong Han, Yuying Tan, Tasuku Kiyuna, Kentaro Miyake, Takashi Murakami, Bartosz Chmielowski, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Michiaki Unno, Fritz C. Eilber, Robert M. Hoffman

Published Aug 12, 2017 · Vol. 8, No. 49 · pp. 85516-85525

The pharmacological role of histone demethylase JMJD3 inhibitor GSK-J4 on glioma cells Research Paper

Aixia Sui, Yongbing Xu, Yitong Li, Qilu Hu, Zeyang Wang, Hongtao Zhang, Junjie Yang, Xiaoqiang Guo, Wenqing Zhao

Published Aug 2, 2017 · Vol. 8, No. 40 · pp. 68591-68598

The performance of 11C-Methionine PET in the differential diagnosis of glioma recurrence Research Paper

Weilin Xu, Liansheng Gao, Anwen Shao, Jingwei Zheng, Jianmin Zhang

Published Jul 5, 2017 · Vol. 8, No. 53 · pp. 91030-91039

Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity Research Paper

Evgeniy Stoyanov, Lina Mizrahi, Devorah Olam, Temima Schnitzer-Perlman, Eithan Galun, Daniel S. Goldenberg

Published May 30, 2017 · Vol. 8, No. 62 · pp. 104772-104784

Methionine restriction on oxidative stress and immune response in dss-induced colitis mice Research Paper

Gang Liu, Lei Yu, Jun Fang, Chien-An Andy Hu, Jie Yin, Hengjia Ni, Wenkai Ren, Veeramuthu Duraipandiyan, Shuai Chen, Naif Abdullah Al-Dhabi, Yulong Yin

Published May 11, 2017 · Vol. 8, No. 27 · pp. 44511-44520

Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development Research Paper

Kun He, Xiwen Zhu, Yan Liu, Chunmu Miao, Tao Wang, Peizhi Li, Lei Zhao, Yaxi Chen, Junhua Gong, Can Cai, Jinzheng Li, Shengwei Li, Xiong Z. Ruan, Jianping Gong

Published Apr 27, 2017 · Vol. 8, No. 23 · pp. 37657-37672

Monocytes, endoplasmic reticulum stress and metabolomics in dogs with multiple organ dysfunction syndrome treated by continuous venovenous hemodiafiltration Research Paper

Yun-Peng Xu, Xiao-Lu Sui, Ai-Sha Zhang, Lei Ye, Feng-Juan Gu, Ji-Hong Chen

Published Mar 23, 2017 · Vol. 8, No. 21 · pp. 34992-35008

Recombinant methioninase effectively targets a Ewingâ€™s sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model Research Paper

Takashi Murakami, Shukuan Li, Qinghong Han, Yuying Tan, Tasuku Kiyuna, Kentaro Igarashi, Kei Kawaguchi, Ho Kyoung Hwang, Kentaro Miyake, Arun S. Singh, Scott D. Nelson, Sarah M. Dry, Yunfeng Li, Yukihiko Hiroshima, Thinzar M. Lwin, Jonathan C. DeLong, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Itaru Endo, Fritz C. Eilber, Robert M. Hoffman

Published Mar 1, 2017 · Vol. 8, No. 22 · pp. 35630-35638

Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation Research Paper

Donghong Zhang, Jinli Lou, Xu Zhang, Lin Zhang, Fei Wang, Danfei Xu, Na Niu, Yidong Wang, Yue Wu, Wei Cui

Published Dec 24, 2016 · Vol. 8, No. 9 · pp. 15377-15392

CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis Research Paper

Xi Jin, Chun-yan Feng, Zun Xiang, Yi-peng Chen, You-ming Li

Published Sep 22, 2016 · Vol. 7, No. 41 · pp. 66455-66467

Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo Research Paper

Hyein Jeon, Jae Hwan Kim, Eunjung Lee, Young Jin Jang, Joe Eun Son, Jung Yeon Kwon, Tae-gyu Lim, Sunghoon Kim, Jung Han Yoon Park, Jong-Eun Kim, Ki Won Lee

Published Aug 25, 2016 · Vol. 7, No. 41 · pp. 67223-67234

MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state Research Paper

FrÃ©dÃ©ric Frottin, Willy V. Bienvenut, JÃ©rÃ´me Bignon, Eric Jacquet, Alvaro Sebastian Vaca Jacome, Alain Van Dorsselaer, Sarah Cianferani, Christine Carapito, Thierry Meinnel, Carmela Giglione

Published Aug 11, 2016 · Vol. 7, No. 39 · pp. 63306-63323

Sex-specific metabolic interactions between liver and adipose tissue in MCD diet-induced non-alcoholic fatty liver disease Research Paper

Yun-Hee Lee, Sou Hyun Kim, Sang-Nam Kim, Hyun-Jung Kwon, Jeong-Dong Kim, Ji Youn Oh, Young-Suk Jung

Published Jul 9, 2016 · Vol. 7, No. 30 · pp. 46959-46971

IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosis Research Paper

Yinjie Gao, Yuan Liu, Mei Yang, Xiaodong Guo, Min Zhang, Hanwei Li, Jin Li, Jingmin Zhao

Published May 9, 2016 · Vol. 7, No. 23 · pp. 33649-33661

APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis Research Paper

Se-Hoon Hong, Won Jae Lee, Young Doo Kim, Hyunjoo Kim, Young-Jun Jeon, Bitna Lim, Dong-Hyung Cho, Won Do Heo, Doo-Hyun Yang, Chan-Young Kim, Han-Kwang Yang, Jin Kuk Yang, Yong-Keun Jung

Published Mar 1, 2016 · Vol. 7, No. 16 · pp. 21601-21617

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models Research Paper

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models Research Paper

Progesterone inhibits contraction and increases TREK-1 potassium channel expression in late pregnant rat uterus Research Paper

S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells Research Paper

S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting MicroRNA 34a/b-methionine adenosyltransferase 2A/2B axis Research Paper

Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

The pharmacological role of histone demethylase JMJD3 inhibitor GSK-J4 on glioma cells Research Paper

The performance of 11C-Methionine PET in the differential diagnosis of glioma recurrence Research Paper

Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity Research Paper

Methionine restriction on oxidative stress and immune response in dss-induced colitis mice Research Paper

Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development Research Paper

Monocytes, endoplasmic reticulum stress and metabolomics in dogs with multiple organ dysfunction syndrome treated by continuous venovenous hemodiafiltration Research Paper

Recombinant methioninase effectively targets a Ewingâ€™s sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model Research Paper

Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation Research Paper

CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis Research Paper

Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo Research Paper

MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state Research Paper

Sex-specific metabolic interactions between liver and adipose tissue in MCD diet-induced non-alcoholic fatty liver disease Research Paper

IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosis Research Paper

APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models Research Paper

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models Research Paper

Progesterone inhibits contraction and increases TREK-1 potassium channel expression in late pregnant rat uterus Research Paper

S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells Research Paper

S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting MicroRNA 34a/b-methionine adenosyltransferase 2A/2B axis Research Paper

Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

The pharmacological role of histone demethylase JMJD3 inhibitor GSK-J4 on glioma cells Research Paper

The performance of 11C-Methionine PET in the differential diagnosis of glioma recurrence Research Paper

Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity Research Paper

Methionine restriction on oxidative stress and immune response in dss-induced colitis mice Research Paper

Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development Research Paper

Monocytes, endoplasmic reticulum stress and metabolomics in dogs with multiple organ dysfunction syndrome treated by continuous venovenous hemodiafiltration Research Paper

Recombinant methioninase effectively targets a Ewingâ€™s sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model Research Paper

Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation Research Paper

CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis Research Paper

Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo Research Paper

MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state Research Paper

Sex-specific metabolic interactions between liver and adipose tissue in MCD diet-induced non-alcoholic fatty liver disease Research Paper

IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosis Research Paper

APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis Research Paper