The Oncosearch | Oncotarget

The multifaceted anti-cancer effects of BRAF-inhibitors Review

Laura Croce, Francesca Coperchini, Flavia Magri, Luca Chiovato, Mario Rotondi

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6623-6640

Keywords: BRAF, BRAF-inhibitors, tumor microenvironment, chemokines, CXCL8

Volasertib preclinical activity in high-risk hepatoblastoma Research Paper

Dina Kats, Cora A. Ricker, Noah E. Berlow, Bénédicte Noblet, Delphine Nicolle, Katell Mevel, Sophie Branchereau, Jean-Gabriel Judde, Cody D. Stiverson, Christina L. Stiverson, Matthew N. Svalina, Teagan Settelmeyer, Kevin Matlock, Melvin Lathara, Charlotte Mussini, James I. Geller, Christopher Noakes, Ido Sloma, Narendra Bharathy, Stefano Cairo, Charles Keller

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6403-6417

Keywords: hepatoblastoma, PLK1, volasertib, liver, cell cycle

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications Research Paper

Albert D. Donnenberg, James D. Luketich, Vera S. Donnenberg

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6456-6465

Keywords: pleural effusion, non-small cell lung cancer, malignant mesothelioma, cytokines, IL-6

Improved surgical resection of metastatic pancreatic cancer using uPAR targeted in vivo fluorescent guidance: comparison with traditional white light surgery Research Paper

Karina Juhl, Anders Christensen, Niclas Rubek, Kirstine Kim Schmidt Karnov, Christian von Buchwald, Andreas Kjaer

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6308-6316

Keywords: optical imaging, near-infrared imaging (NIR), NIR-I, urokinase plasminogen activator receptor (uPAR), cancer

Central nervous system-specific efficacy of CDK4/6 inhibitors in randomized controlled trials for metastatic breast cancer Research Paper

Long V. Nguyen, Karlee Searle, Katarzyna J. Jerzak

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6317-6322

Keywords: breast neoplasms, blood-brain barrier, palbociclib, ribociclib, abemaciclib

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Andrew J. Sanders, Sioned Owen, Liam D. Morgan, Fiona Ruge, Ross J. Collins, Lin Ye, Malcolm D. Mason, Wen G. Jiang

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6362-6377

Keywords: ALCAM, prostate cancer, bone, metastasis, serum biomarker

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Gozde Uzunalli, Alexandra M. Dieterly, Chinyere M. Kemet, Hsin-Yi Weng, Arvin H. Soepriatna, Craig J. Goergen, Aparna B. Shinde, Michael K. Wendt, L. Tiffany Lyle

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6334-6348

Keywords: blood-brain barrier, blood-tumor barrier, non-small cell lung cancer, brain metastasis, aquaporin-4

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Jun Gong, Edik M. Blais, Joseph R. Bender, Michelle Guan, Veronica Placencio-Hickok, Emanuel F. Petricoin, Michael J. Pishvaian, Gary Gregory, Richard Tuli, Andrew E. Hendifar

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6260-6268

Keywords: pancreatic neuroendocrine tumors, genomic profiling, proteomic profiling, molecular pathways, co-occurring alterations

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells Research Paper

Channay Naidoo, Cherie Ann Kruger, Heidi Abrahamse

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6079-6095

Keywords: metastatic melanoma, nano active targeting, zinc phthalocyanine tetra-sulphonic acid, photodynamic therapy

Extramammary Paget disease shows differential expression of B7 family members B7-H3, B7-H4, PD-L1, PD-L2 and cancer/testis antigens NY-ESO-1 and MAGE-A Research Paper

Maryam Pourmaleki, Jonathan H. Young, Nicholas D. Socci, Sarah Chiang, Marcia Edelweiss, Yanyun Li, Mianlei Zhang, Lev Roshal, Dennis S. Chi, Klaus J. Busam, Ingo K. Mellinghoff, Travis J. Hollmann

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6152-6167

Keywords: extramammary paget disease, B7 family, cancer/testis antigens, targetable molecules, immunotherapy

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma Research Paper

Shatha Albattal, Meshael Alswailem, Yosra Moria, Hindi Al-Hindi, Majed Dasouki, Mohamed Abouelhoda, Hala Aba Alkhail, Entissar Alsuhaibani, Ali S. Alzahrani

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5919-5931

Keywords: pheochromocytoma, paraganglioma, mutations, NGS, SDHB

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Andrew J. Sanders, Sioned Owen, Liam Morgan, Fiona Ruge, Ross Collins, Lin Ye, Malcolm Mason, Wenguo Jiang

Published Oct 14, 2019

Keywords: ALCAM, prostate cancer, bone, metastasis, serum biomarker

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line Research Paper

Luana de O. Lopes, Jersey H. Maués, Hygor Ferreira-Fernandes, France K. Yoshioka, Severino C. Sousa Júnior, Alcemir R. Santos, Helem F. Ribeiro, Juan A. Rey, Paulo C. Soares, Rommel R. Burbano, Giovanny R. Pinto

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5768-5779

Keywords: stomach neoplasms, MYC oncogene, transcriptome, gene expression profiling, prognosis

Upregulation of C1-inhibitor in pancreatic cancer Research Paper

Kurt Osther, Karolina Förnvik, Emma Liljedahl, Leif G. Salford, Henrietta Nittby Redebrandt

Published Oct 1, 2019 · Vol. 10, No. 55 · pp. 5703-5712

Keywords: complement system, C1-inhibitor, pancreatic cancer, immunotherapy, cancer

Clinical significance of evaluating hormone receptor and HER2 protein using cell block against metastatic breast cancer: a multi-institutional study Research Paper

Akira Matsui, Yuya Murata, Norikazu Masuda, Kiyoshi Mori, Masato Takahashi, Katsushige Yamashiro, Kenjirou Aogi, Shigeto Maeda, Masahiro Itou, Shinji Ozaki, Kazuya Kuraoka, Yasuyuki Satou, Shu Ichihara, Eriko Tokunaga, Kenichi Taguchi, Takanori Watanabe, Hiroyoshi Suzuki, Aiko Nagayama, Rieko Nishimura

Published Oct 1, 2019 · Vol. 10, No. 55 · pp. 5680-5689

Keywords: metastatic breast cancer, receptor discordance, cell block, cytological specimen, prognosis

Ezrin, more than a metastatic detERMinant? Editorial

Victoria Hoskin, Abdi Ghaffari, Bruce E. Elliott

Published Sep 25, 2019 · Vol. 10, No. 63 · pp. 6755-6757

Keywords: ezrin, metastasis, breast cancer, therapeutic target

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial Research Paper

Rajnish Nagarkar, Darshana Patil, Timothy Crook, Vineet Datta, Sagar Bhalerao, Sonal Dhande, Vijay Palwe, Shirsendu Roy, Prakash Pandit, Ashwini Ghaisas, Raymond Page, Harjeetsingh Kathuria, Ajay Srinivasan, Dadasaheb Akolkar

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5605-5621

Keywords: precision oncology, encyclopedic tumor analysis, personalized cancer treatment, objective response rate, progression free survival

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor Research Paper

Jamie M. Aye, Laura L. Stafman, Adele P. Williams, Evan F. Garner, Jerry E. Stewart, Joshua C. Anderson, Smitha Mruthyunjayappa, Mary G. Waldrop, Caroline D. Goolsby, Hooper R. Markert, Colin Quinn, Raoud Marayati, Elizabeth Mroczek-Musulman, Christopher D. Willey, Karina J. Yoon, Kimberly F. Whelan, Elizabeth A. Beierle

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5534-5548

Keywords: kinase inhibition, Wilms tumor

Cathepsin L secretion by host and neoplastic cells potentiates invasion Research Paper

Samantha S. Dykes, Henrietta O. Fasanya, Dietmar W. Siemann

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5560-5568

Keywords: breast cancer, macrophage, invasion, cathepsin L

Excision repair cross-complementing group-1 (ERCC1) induction kinetics and polymorphism are markers of inferior outcome in patients with colorectal cancer treated with oxaliplatin Research Paper

Devika Rao, Atrayee Basu Mallick, Titto Augustine, Cecilia Daroqui, Jeeshan Jiffry, Amartej Merla, Imran Chaudhary, Raviraja Seetharam, Arjun Sood, Srikanth Gajavelli, Santiago Aparo, Lakshmi Rajdev, Andreas Kaubisch, Jennifer Chuy, Abdissa Negassa, John M. Mariadason, Radhashree Maitra, Sanjay Goel

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5510-5522

Keywords: oxaliplatin, colorectal cancer, ERCC1, FOLFOX, resistance

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European Cancer and Oncology Congress

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The multifaceted anti-cancer effects of BRAF-inhibitors Review

Volasertib preclinical activity in high-risk hepatoblastoma Research Paper

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications Research Paper

Improved surgical resection of metastatic pancreatic cancer using uPAR targeted in vivo fluorescent guidance: comparison with traditional white light surgery Research Paper

Central nervous system-specific efficacy of CDK4/6 inhibitors in randomized controlled trials for metastatic breast cancer Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells Research Paper

Extramammary Paget disease shows differential expression of B7 family members B7-H3, B7-H4, PD-L1, PD-L2 and cancer/testis antigens NY-ESO-1 and MAGE-A Research Paper

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line Research Paper

Upregulation of C1-inhibitor in pancreatic cancer Research Paper

Clinical significance of evaluating hormone receptor and HER2 protein using cell block against metastatic breast cancer: a multi-institutional study Research Paper

Ezrin, more than a metastatic detERMinant? Editorial

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial Research Paper

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor Research Paper

Cathepsin L secretion by host and neoplastic cells potentiates invasion Research Paper

Excision repair cross-complementing group-1 (ERCC1) induction kinetics and polymorphism are markers of inferior outcome in patients with colorectal cancer treated with oxaliplatin Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The multifaceted anti-cancer effects of BRAF-inhibitors Review

Volasertib preclinical activity in high-risk hepatoblastoma Research Paper

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications Research Paper

Improved surgical resection of metastatic pancreatic cancer using uPAR targeted in vivo fluorescent guidance: comparison with traditional white light surgery Research Paper

Central nervous system-specific efficacy of CDK4/6 inhibitors in randomized controlled trials for metastatic breast cancer Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells Research Paper

Extramammary Paget disease shows differential expression of B7 family members B7-H3, B7-H4, PD-L1, PD-L2 and cancer/testis antigens NY-ESO-1 and MAGE-A Research Paper

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line Research Paper

Upregulation of C1-inhibitor in pancreatic cancer Research Paper

Clinical significance of evaluating hormone receptor and HER2 protein using cell block against metastatic breast cancer: a multi-institutional study Research Paper

Ezrin, more than a metastatic detERMinant? Editorial

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial Research Paper

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor Research Paper

Cathepsin L secretion by host and neoplastic cells potentiates invasion Research Paper

Excision repair cross-complementing group-1 (ERCC1) induction kinetics and polymorphism are markers of inferior outcome in patients with colorectal cancer treated with oxaliplatin Research Paper