The Oncosearch | Oncotarget

The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung Research Paper

Mirjana Grujic, Aida Paivandy, Ann-Marie Gustafson, Allan R. Thomsen, Helena Ohrvik, Gunnar Pejler

Published Feb 15, 2017 · Vol. 8, No. 15 · pp. 25066-25079

The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma Research Paper

Jeong Hyun Cho, Hyo-Ji Lee, Hyun-Jeong Ko, Byung-Il Yoon, Jongseon Choe, Keun-Cheol Kim, Tae-Wook Hahn, Jeong A. Han, Sun Shim Choi, Young Mee Jung, Kee-Ho Lee, Yun-Sil Lee, Yu-Jin Jung

Published Feb 15, 2017 · Vol. 8, No. 15 · pp. 24932-24948

Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways Research Paper

Guanzhao Liang, Musang Liu, Qiong Wang, Yongnian Shen, Huan Mei, Dongmei Li, Weida Liu

Published Feb 14, 2017 · Vol. 8, No. 17 · pp. 28510-28525

Blockade of Rho-associated protein kinase (ROCK) inhibits the contractility and invasion potential of cancer stem like cells Research Paper

Srisathya Srinivasan, Vandhana Ashok, Sagarajit Mohanty, Alakesh Das, Sreya Das, Sushant Kumar, Shamik Sen, Rahul Purwar

Published Feb 10, 2017 · Vol. 8, No. 13 · pp. 21418-21428

PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p Research Paper

Valentina Audrito, Sara Serra, Aureliano Stingi, Francesca Orso, Federica Gaudino, Cinzia Bologna, Francesco Neri, Giulia Garaffo, Romina Nassini, Gianna Baroni, Eliana Rulli, Daniela Massi, Salvatore Oliviero, Roberto Piva, Daniela Taverna, Mario MandalÃ, Silvia Deaglio

Published Feb 9, 2017 · Vol. 8, No. 9 · pp. 15894-15911

Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma Research Paper

Katherine J. Ransohoff, Wenting Wu, Hyunje G. Cho, Harvind C. Chahal, Yuan Lin, Hong-Ji Dai, Christopher I. Amos, Jeffrey E. Lee, Jean Y. Tang, David A. Hinds, Jiali Han, Qingyi Wei, Kavita Y. Sarin

Published Feb 9, 2017 · Vol. 8, No. 11 · pp. 17586-17592

Tetraspanin 8 is a novel regulator of ILK-driven Î²1 integrin adhesion and signaling in invasive melanoma cells Research Paper

Manale El Kharbili, Clement Robert, Tiffany Witkowski, Emmanuelle Danty-Berger, Laetitia Barbollat-Boutrand, Ingrid Masse, Nicolas Gadot, Arnaud de la Fouchardiere, Paul C. McDonald, Shoukat Dedhar, Francois Le Naour, Francoise Degoul, Odile Berthier-Vergnes

Published Feb 4, 2017 · Vol. 8, No. 10 · pp. 17140-17155

The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRAS^Q61K melanoma Priority Research Paper

Cynthia M. Simbulan-Rosenthal, Sivanesan Dakshanamurthy, Anirudh Gaur, You-Shin Chen, Hong-Bin Fang, Maryam Abdussamad, Hengbo Zhou, John Zapas, Valerie Calvert, Emanuel F. Petricoin, Michael B. Atkins, Stephen W. Byers, Dean S. Rosenthal

Published Feb 2, 2017 · Vol. 8, No. 8 · pp. 12576-12595

Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation Research Paper

So Young Kim, Dongxu Kang, Hye Jin Choi, Yeonsoo Joo, Joo-Hang Kim, Jae J. Song

Published Feb 2, 2017 · Vol. 8, No. 9 · pp. 15858-15877

The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types Research Paper

Laura Fancello, Kim R. Kampen, Isabel J.F. Hofman, Jelle Verbeeck, Kim De Keersmaecker

Published Jan 29, 2017 · Vol. 8, No. 9 · pp. 14462-14478

The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo Research Paper

Laurence Booth, Jane L. Roberts, Cindy Sander, John Lee, John M. Kirkwood, Andrew Poklepovic, Paul Dent

Published Jan 27, 2017 · Vol. 8, No. 10 · pp. 16367-16386

MAPK pathway inhibition induces MET and GAB1 levels, priming BRAF mutant melanoma for rescue by hepatocyte growth factor Research Paper

Sean Caenepeel, Keegan Cooke, Sarah Wadsworth, Guo Huang, Lidia Robert, Blanca Homet Moreno, Giulia Parisi, Elaina Cajulis, Richard Kendall, Pedro Beltran, Antoni Ribas, Angela Coxon, Paul E. Hughes

Published Jan 27, 2017 · Vol. 8, No. 11 · pp. 17795-17809

MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy Research Paper

Simon Laban, Gregor Giebel, Niklas KlÃ¼mper, Andreas SchrÃ¶ck, Johannes Doescher, Giulio Spagnoli, Julia Thierauf, Marie-Nicole Theodoraki, Romain Remark, Sacha Gnjatic, Rosemarie Krupar, Andrew G. Sikora, Geert Litjens, Niels Grabe, Glen Kristiansen, Friedrich Bootz, Patrick J. Schuler, Cornelia Brunner, Johannes BrÃ¤gelmann, Thomas K. Hoffmann, Sven Perner

Published Jan 27, 2017 · Vol. 8, No. 9 · pp. 14719-14735

Identification of novel follicular dendritic cell sarcoma markers, FDCSP and SRGN, by whole transcriptome sequencing Research Paper

Luisa Lorenzi, Claudia DÃ¶ring, Tobias Rausch, Vladimir Benes, Silvia Lonardi, Mattia Bugatti, Elias Campo, JosÃ© CabeÃ§adas, Ingrid Simonitsch-Klupp, Anita Borges, Jay Mehta, Claudio Agostinelli, Stefano Aldo Pileri, Fabio Facchetti, Martin-Leo Hansmann, Sylvia Hartmann

Published Jan 27, 2017 · Vol. 8, No. 10 · pp. 16463-16472

Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment Research Paper

Daria Marley Kemp, Alyson Pidich, Mary Larijani, Rebecca Jonas, Elizabeth Lash, Takami Sato, Mizue Terai, Maria De Pizzol, Marcello Allegretti, Olga Igoucheva, Vitali Alexeev

Published Jan 24, 2017 · Vol. 8, No. 9 · pp. 14428-14442

MicroRNAs in melanoma development and resistance to target therapy Review

Luigi Fattore, Susan Costantini, Debora Malpicci, Ciro Francesco Ruggiero, Paolo Antonio Ascierto, Carlo M. Croce, Rita Mancini, Gennaro Ciliberto

Published Jan 19, 2017 · Vol. 8, No. 13 · pp. 22262-22278

Clinicopathological significance of intratumoral and peritumoral lymphocytes and lymphocyte score based on the histologic subtypes of cutaneous melanoma Research Paper

Cheol Keun Park, Sang Kyum Kim

Published Jan 19, 2017 · Vol. 8, No. 9 · pp. 14759-14769

microRNA-625 inhibits tumorigenicity by suppressing proliferation, migration and invasion in malignant melanoma Research Paper

Wei Fang, Yibin Fan, Zhenzong Fa, Jinhua Xu, Hongyu Yu, Pu Li, Julin Gu

Published Jan 18, 2017 · Vol. 8, No. 8 · pp. 13253-13263

The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis Research Paper

Anastasia De Luca, Debora Carpanese, Maria Cristina Rapanotti, Tara Mayte Suarez Viguria, Maria Antonietta Forgione, Dante Rotili, Chiara Fulci, Egidio Iorio, Luigi Quintieri, Sergio Chimenti, Luca Bianchi, Antonio Rosato, Anna Maria Caccuri

Published Jan 17, 2017 · Vol. 8, No. 9 · pp. 15520-15538

FAK regulates E-cadherin expression via p-Src^Y416/p-ERK_1/2/p-Stat3^Y705 and PPARÎ³/miR-125b/Stat3 signaling pathway in B16F10 melanoma cells Research Paper

Guoshun Pei, Yan Lan, Dianhua Chen, Lina Ji, Zi-chun Hua

Published Jan 17, 2017 · Vol. 8, No. 8 · pp. 13898-13908

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The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung Research Paper

The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma Research Paper

Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways Research Paper

Blockade of Rho-associated protein kinase (ROCK) inhibits the contractility and invasion potential of cancer stem like cells Research Paper

PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p Research Paper

Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma Research Paper

Tetraspanin 8 is a novel regulator of ILK-driven Î²1 integrin adhesion and signaling in invasive melanoma cells Research Paper

The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRAS^Q61K melanoma Priority Research Paper

Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation Research Paper

The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types Research Paper

The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo Research Paper

MAPK pathway inhibition induces MET and GAB1 levels, priming BRAF mutant melanoma for rescue by hepatocyte growth factor Research Paper

MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy Research Paper

Identification of novel follicular dendritic cell sarcoma markers, FDCSP and SRGN, by whole transcriptome sequencing Research Paper

Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment Research Paper

MicroRNAs in melanoma development and resistance to target therapy Review

Clinicopathological significance of intratumoral and peritumoral lymphocytes and lymphocyte score based on the histologic subtypes of cutaneous melanoma Research Paper

microRNA-625 inhibits tumorigenicity by suppressing proliferation, migration and invasion in malignant melanoma Research Paper

The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis Research Paper

FAK regulates E-cadherin expression via p-Src^Y416/p-ERK_1/2/p-Stat3^Y705 and PPARÎ³/miR-125b/Stat3 signaling pathway in B16F10 melanoma cells Research Paper

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European Cancer and Oncology Congress

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Post-Publication Promotion

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The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung Research Paper

The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma Research Paper

Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways Research Paper

Blockade of Rho-associated protein kinase (ROCK) inhibits the contractility and invasion potential of cancer stem like cells Research Paper

PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p Research Paper

Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma Research Paper

Tetraspanin 8 is a novel regulator of ILK-driven Î²1 integrin adhesion and signaling in invasive melanoma cells Research Paper

The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRASQ61K melanoma Priority Research Paper

Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation Research Paper

The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types Research Paper

The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo Research Paper

MAPK pathway inhibition induces MET and GAB1 levels, priming BRAF mutant melanoma for rescue by hepatocyte growth factor Research Paper

MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy Research Paper

Identification of novel follicular dendritic cell sarcoma markers, FDCSP and SRGN, by whole transcriptome sequencing Research Paper

Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment Research Paper

MicroRNAs in melanoma development and resistance to target therapy Review

Clinicopathological significance of intratumoral and peritumoral lymphocytes and lymphocyte score based on the histologic subtypes of cutaneous melanoma Research Paper

microRNA-625 inhibits tumorigenicity by suppressing proliferation, migration and invasion in malignant melanoma Research Paper

The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis Research Paper

FAK regulates E-cadherin expression via p-SrcY416/p-ERK1/2/p-Stat3Y705 and PPARÎ³/miR-125b/Stat3 signaling pathway in B16F10 melanoma cells Research Paper

The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRAS^Q61K melanoma Priority Research Paper

FAK regulates E-cadherin expression via p-Src^Y416/p-ERK_1/2/p-Stat3^Y705 and PPARÎ³/miR-125b/Stat3 signaling pathway in B16F10 melanoma cells Research Paper