The Oncosearch | Oncotarget

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Jan A. Kaczmarczyk, Rhonda R. Roberts, Brian T. Luke, King C. Chan, Carly M. Van Wagoner, Robin A. Felder, Richard G. Saul, Colantonio Simona, Josip Blonder

Published Sep 3, 2021 · Vol. 12, No. 20 · pp. 2022-2038

Keywords: lung cancer, proteomics, 2D vs. 3D cultured cells, preclinical testing model, drug target discovery

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Adam S. Kittai, Olga V. Danilova, Vi Lam, Tingting Liu, Nur Bruss, Scott Best, Guang Fan, Alexey V. Danilov

Published Aug 23, 2021 · Vol. 12, No. 20 · pp. 2068-2074

Keywords: pevonedistat, T-cell lymphoma, chromosomal instability, anaphase catastrophe

Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis Research Paper

Kazuhiro Kitajima, Hidetoshi Matsuo, Atsushi Kono, Kozo Kuribayashi, Takashi Kijima, Masaki Hashimoto, Seiki Hasegawa, Takamichi Murakami, Koichiro Yamakado

Published May 21, 2021 · Vol. 12, No. 12 · pp. 1187-1196

Keywords: mesothelioma, artificial intelligence, deep learning, FDG (fluorodeoxyglucose), PET-CT (positron emission tomography-computed tomography)

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cells Research Paper

Marpe Bam, Sreenivasulu Chintala, Kaleigh Fetcko, Brooke Carmen Williamsen, Seema Siraj, Sheng Liu, Jun Wan, Xiaoling Xuei, Yunlong Liu, Adam T. Leibold, Mahua Dey

Published Apr 25, 2021 · Vol. 12, No. 10 · pp. 967-981

Keywords: glioblastoma, malignant glioma, CD4+ T cell, DNA methylation, brain cancer

Down regulation of lactate dehydrogenase initiates apoptosis in HeLa and MCF-7 cancer cells through increased voltage-dependent anion channel protein and inhibition of BCL2 Research Paper

Suhail Al-Salam, Karthishwaran Kandhan, Manjusha Sudhadevi

Published Apr 20, 2021 · Vol. 12, No. 9 · pp. 923-935

Keywords: cancer metabolism, LDHA, apoptosis, VDAC

Piperlongumine promotes death of retinoblastoma cancer cells Research Paper

Nathalie Allaman-Pillet, Daniel F. Schorderet

Published Apr 8, 2021 · Vol. 12, No. 9 · pp. 907-916

Keywords: cancer, retinoblastoma, piperlongumine, programmed cell death

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Sateja Paradkar, James Herrington, Adam Hendricson, Piyasena Hewawasam, Mark Plummer, Denton Hoyer, Ranjini K. Sundaram, Yulia V. Surovtseva, Ranjit S. Bindra

Published Mar 27, 2021 · Vol. 12, No. 9 · pp. 891-906

Keywords: glioblastoma, radiosensitizers, mibefradil, DNA repair, alternative non-homologous end joining

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Radhika R. Gudi, Harinarayanan Janakiraman, Philip H. Howe, Viswanathan Palanisamy, Chenthamarakshan Vasu

Published Mar 27, 2021 · Vol. 12, No. 8 · pp. 807-822

Keywords: tumorigenesis, epithelial-mesenchymal transition, oral squamous cell carcinoma, EGFR, CPAP

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Chandni Desai, Jon Thomason, Jordan L. Kohlmeyer, Anna C. Reisetter, Parmanand Ahirwar, Khadijeh Jahanseir, Mariah Leidinger, Georgina Ofori-Amanfo, Karen Fritchie, Sadanandan E. Velu, Patrick Breheny, Dawn E. Quelle, Munir R. Tanas

Published Mar 21, 2021 · Vol. 12, No. 8 · pp. 740-755

Keywords: sarcoma, YAP, TAZ, p53-MDM2, RABL6A

The role of immune surveillance in malignant transformation of benign salivary gland tumors Research Perspective

Maximilian Linxweiler, Jingming Wang, Luc G.T. Morris

Published Feb 10, 2021 · Vol. 12, No. 7 · pp. 592-595

Keywords: salivary tumor, salivary cancer, pleomorphic adenoma, immune surveillance

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

H.M.C. Shantha Kumara, Elie Sutton, Otavia L. Caballero, Tao Su, Xiaohong Yan, Aqeel Ahmed, Sonali A.C. Herath, Vesna Cekic, Linda Njoh, Daniel D. Kirchoff, Richard L. Whelan

Published Feb 9, 2021 · Vol. 12, No. 5 · pp. 412-421

Keywords: cancer testis antigens, colorectal cancer, CABYR a/b, c

Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers Review

Nataliya Pidkovka, Olena Rachkevych, Abbes Belkhiri

Published Feb 5, 2021 · Vol. 12, No. 4 · pp. 379-391

Keywords: cytochrome P450 epoxygenases, extrahepatic CYPs, gastrointestinal cancers, epoxyeicosatrienoic acids, arachidonic acid

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast Research Paper

Aviral Kumar, David S. Nayakanti, Kiran K. Mangalaparthi, Veena Gopinath, Nandyala Venkat Narsimha Reddy, Krishna Govindan, Geeta Voolapalli, Prashant Kumar, Lekha Dinesh Kumar

Published Feb 3, 2021 · Vol. 12, No. 5 · pp. 507-518

Keywords: breast tumors, fibroepithelial lesions, phyllodes, iTRAQ, quantitative proteomics

Quercetin shortened survival of radio-resistant B-1 cells in vitro and in vivo by restoring miR15a/16 expression Research Paper

Yasmim Alefe Leuzzi Ramos, Olivia Fonseca Souza, Marilia Campos Tavares Novo, Caroline Ferreira Cunha Guimarães, Ana Flavia Popi

Published Jan 29, 2021 · Vol. 12, No. 4 · pp. 355-365

Keywords: B-1 cells, chronic lymphocytic leukemia, quercetin, Wnt, miRNA

Testosterone deficiency in men receiving immunotherapy for malignant melanoma Research Paper

Madeline Peters, Amy Pearlman, William Terry, Sarah L. Mott, Varun Monga

Published Jan 22, 2021 · Vol. 12, No. 3 · pp. 199-208

Keywords: cancer, melanoma, immunotherapy, testosterone deficiency, androgens

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling Research Perspective

Jordan L. Kohlmeyer, David J. Gordon, Munir R. Tanas, Rebecca D. Dodd, Varun Monga, Benjamin W. Darbro, Dawn E. Quelle

Published Dec 26, 2020 · Vol. 12, No. 1 · pp. 10-14

Keywords: MPNST, RABL6A-RB1 signaling, CDK4/6 and MEK inhibitors, Ras, targeted cancer therapy

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Marie-Luise Hilbers, Regula Brändli, Beda Mühleisen, Sandra N. Freiberger, Joanna Mangana, Reinhard Dummer

Published Dec 18, 2020 · Vol. 12, No. 2 · pp. 125-130

Keywords: spitzoid nevi, melanocytic lesion, dermatopathology, pediatric dermatology, diagnostic algorithm

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Hector A. Cuello, Gretel M. Ferreira, Cynthia A. Gulino, Alejandro Gomez Toledo, Valeria I. Segatori, Mariano R. Gabri

Published Dec 16, 2020 · Vol. 11, No. 52 · pp. 4822-4835

Keywords: glioma, glioblastoma, Lewis glycans, histone acetylation, N-glycans

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

Karam Khaddour, Joshua Dowling, Jiayi Huang, Martha Council, David Chen, Lynn Cornelius, Tanner Johanns, Sonika Dahiya, George Ansstas

Published Dec 13, 2020 · Vol. 11, No. 52 · pp. 4836-4844

Keywords: metastatic melanoma, immune checkpoint inhibitor, temozolomide, acquired resistance, beta-2 microglobulin

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Katarina Reis, Jack L. Arbiser, Anders Hjerpe, Katalin Dobra, Pontus Aspenström

Published Dec 4, 2020 · Vol. 11, No. 50 · pp. 4637-4647

Keywords: malignant mesothelioma, actin dynamics, vimentin, cytoskeleton, imipramine blue

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Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis Research Paper

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cells Research Paper

Down regulation of lactate dehydrogenase initiates apoptosis in HeLa and MCF-7 cancer cells through increased voltage-dependent anion channel protein and inhibition of BCL2 Research Paper

Piperlongumine promotes death of retinoblastoma cancer cells Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

The role of immune surveillance in malignant transformation of benign salivary gland tumors Research Perspective

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers Review

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast Research Paper

Quercetin shortened survival of radio-resistant B-1 cells in vitro and in vivo by restoring miR15a/16 expression Research Paper

Testosterone deficiency in men receiving immunotherapy for malignant melanoma Research Paper

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling Research Perspective

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis Research Paper

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cells Research Paper

Down regulation of lactate dehydrogenase initiates apoptosis in HeLa and MCF-7 cancer cells through increased voltage-dependent anion channel protein and inhibition of BCL2 Research Paper

Piperlongumine promotes death of retinoblastoma cancer cells Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

The role of immune surveillance in malignant transformation of benign salivary gland tumors Research Perspective

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers Review

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast Research Paper

Quercetin shortened survival of radio-resistant B-1 cells in vitro and in vivo by restoring miR15a/16 expression Research Paper

Testosterone deficiency in men receiving immunotherapy for malignant melanoma Research Paper

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling Research Perspective

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper