The Oncosearch | Oncotarget

Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells. Research Paper

Claire B. Pollock, Sara McDonough, Victor S. Wang, Hyojung Lee, Lymor Ringer, Xin Li, Cristina Prandi, Richard J. Lee, Adam S. Feldman, Hinanit Koltai, Yoram Kapulnik, Olga C. Rodriguez, Richard Schlegel, Christopher Albanese, Ronit I. Yarden

Published Apr 2, 2014 · Vol. 5, No. 6 · pp. 1683-1698

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation Research Paper

Tom Groot Kormelink, Desmond G. Powe, Sylvia A. Kuijpers, Abulikemu Abudukelimu, Marcel H.A.M. Fens, Ebel H.E. Pieters, Willemiek W. Kassing-van der Ven, Hany O. Habashy, Ian O. Ellis, Bart R. Blokhuis, Marco Thio, Wim E. Hennink, Gert Storm, Frank A. Redegeld, Raymond M. Schiffelers

Published Mar 26, 2014 · Vol. 5, No. 10 · pp. 3159-3167

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor Research Paper

Koichi Azuma, Akihiko Kawahara, Kahori Sonoda, Kazutaka Nakashima, Kousuke Tashiro, Kosuke Watari, Hiroto Izumi, Masayoshi Kage, Michihiko Kuwano, Mayumi Ono, Tomoaki Hoshino

Published Mar 26, 2014 · Vol. 5, No. 15 · pp. 5908-5919

Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo Research Paper

Shou-Hung Tang, Hsu-Shan Huang, Hong-Ui Wu, Yi-Ta Tsai, Mei-Jen Chuang, Cheng-Ping Yu, Shih-Ming Huang, Guang-Huan Sun, Sun-Yran Chang, Pei-Wen Hsiao, Dah-Shyong Yu, Tai-Lung Cha

Published Mar 26, 2014 · Vol. 5, No. 21 · pp. 10342-10355

YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes. Research Paper

Erica Lorenzetto, Monica Brenca, Mattia Boeri, Carla Verri, Elena Piccinin, Patrizia Gasparini, Federica Facchinetti, Sabrina Rossi, Giuliana Salvatore, Maura Massimino, Gabriella Sozzi, Roberta Maestro, Piergiorgio Modena

Published Mar 23, 2014 · Vol. 5, No. 9 · pp. 2608-2621

Tumor hypoxia enhances Non-Small Cell Lung Cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling Research Paper

Jun Zhang, Ji Cao, Shenglin Ma, Rong Dong, Wen Meng, Meidan Ying, Qinjie Weng, Zibo Chen, Jian Ma, Qingxia Fang, Qiaojun He, Bo Yang

Published Mar 22, 2014 · Vol. 5, No. 20 · pp. 9664-9677

Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine Research Paper

Gavin M. Wright, Hongdo Do, Jonathan Weiss, Naveed Alam, Vivek Rathi, Marzena Walkiewicz, Thomas John, Prudence Russell, Alexander Dobrovic

Published Mar 22, 2014 · Vol. 5, No. 8 · pp. 2107-2115

Targeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma Research Paper

Kaishun Hu, Dan Liao, Wenjing Wu, An-Jia Han, Hui-Juan Shi, Fen Wang, Xin Wang, Li Zhong, Tingmei Duan, Yuanzhong Wu, Jingying Cao, Jianjun Tang, Yi Sang, Li Wang, Xiaobin Lv, Shuangbing Xu, Ru-Hua Zhang, Wu-Guo Deng, Sheng-Ping Li, Yi-Xin Zeng, Tiebang Kang

Published Mar 21, 2014 · Vol. 5, No. 10 · pp. 3088-3100

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis Research Paper

Xi Tang, Sumit S. Mahajan, Liem T. Nguyen, FranÃ§ois BÃ©liveau, Richard Leduc, Julian A. Simon, Valeri Vasioukhin

Published Mar 16, 2014 · Vol. 5, No. 5 · pp. 1352-1362

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

Qiong Wang, Shaoqing Shi, Weiyang He, Mabel T. Padilla, Lin Zhang, Xia Wang, Bin Zhang, Yong Lin

Published Feb 25, 2014 · Vol. 5, No. 5 · pp. 1304-1314

FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway Research Paper

Janani Ravi, Amita Sneh, Konstantin Shilo, Mohd W. Nasser, Ramesh K. Ganju

Published Feb 21, 2014 · Vol. 5, No. 9 · pp. 2475-2486

Keywords: NSCLC, EGFR, Met-F-AEA, FAAH

Arsenic-induced sub-lethal stress reprograms human bronchial epithelial cells to CD61Â¯ cancer stem cells Research Paper

Qingshan Chang, Bailing Chen, Chitra Thakur, Yongju Lu, Fei Chen

Published Feb 19, 2014 · Vol. 5, No. 5 · pp. 1290-1303

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 Research Paper

Andrew E. Tee, Dora Ling, Charlotte Nelson, Bernard Atmadibrata, Marcel E. Dinger, Ning Xu, Tamio Mizukami, Pei Y. Liu, Bing Liu, Belamy Cheung, Eddy Pasquier, Michelle Haber, Murray D. Norris, Takayoshi Suzuki, Glenn M. Marshall, Tao Liu

Published Feb 18, 2014 · Vol. 5, No. 7 · pp. 1793-1804

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer Research Paper

Shigeru Kawabata, Chun-Te Chiang, Junji Tsurutani, Hideaki Shiga, Matthew L. Arwood, Takefumi Komiya, Joell J. Gills, Regan M. Memmott, Phillip A. Dennis

Published Feb 16, 2014 · Vol. 5, No. 4 · pp. 1062-1070

Keywords: Rapamycin, Pemetrexed, Drug synergy, mTOR, Thymidylate Synthase, Lung Cancer

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer Research Paper

Saverio Candido, Roberta Maestro, Jerry Polesel, Alessia Catania, Francesca Maira, Santo S. Signorelli, James A. McCubrey, Massimo Libra

Published Feb 1, 2014 · Vol. 5, No. 6 · pp. 1576-1594

Keywords: NGAL, LCN2, Lipocalin 2, mRNA expression, cancer, biomarker, prognostic factor, metastasis, protein expression

Sp1-mediated microRNA-182 expression regulates lung cancer progression Research Paper

Wen-Bin Yang, Ping-Hsin Chen, Tsung-I Hsu, Tzu-Fun Fu, Wu-Chou Su, Hungjiun Liaw, Wen-Chang Chang, Jan-Jong Hung

Published Jan 25, 2014 · Vol. 5, No. 3 · pp. 740-753

Keywords: Sp1, miR-182, FOXO3, Lung cancer

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Ulrike M. Litzenburger, Christiane A. Opitz, Felix Sahm, Katharina J. Rauschenbach, Saskia Trump, Marcus Winter, Martina Ott, Katharina Ochs, Christian Lutz, Xiangdong Liu, Natasa Anastasov, Irina Lehmann, Thomas HÃ¶fer, Andreas von Deimling, Wolfgang Wick, Michael Platten

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 1038-1051

Keywords: IDO, immunosuppression, autoactivation loop

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Jakob H. Mikkelsen, Zachary T. Resch, Bhanu Kalra, Gopal Savjani, Ajay Kumar, Cheryl A. Conover, Claus Oxvig

Published Jan 17, 2014 · Vol. 5, No. 4 · pp. 1014-1025

Keywords: insulin-like growth factor receptor, pregnancy-associated plasma protein-A, proteolytic inhibition, therapeutic antibody, xenograft mouse model

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Ukhyun Jo, Kyong Hwa Park, Young Mi Whang, Jae Sook Sung, Nam Hee Won, Jong Kuk Park, Yeul Hong Kim

Published Jan 16, 2014 · Vol. 5, No. 5 · pp. 1265-1278

Keywords: EGFR, endocytosis, gefitinib, lung cancer, Rab25

Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function Research Paper

Bongkun Choi, Eun-Jin Lee, Da-Hyun Song, Sung-Chul Yoon, Yeon-Ho Chung, Yongsaeng Jang, Sang-Min Kim, Youngsup Song, Sang-Wook Kang, Seung-Yong Yoon, Eun-Ju Chang

Published Jan 15, 2014 · Vol. 5, No. 2 · pp. 481-492

Keywords: breast cancer, PTX3, osteoclast, RANKL, osteolysis

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Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells. Research Paper

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation Research Paper

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor Research Paper

Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo Research Paper

YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes. Research Paper

Tumor hypoxia enhances Non-Small Cell Lung Cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling Research Paper

Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine Research Paper

Targeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma Research Paper

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis Research Paper

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway Research Paper

Arsenic-induced sub-lethal stress reprograms human bronchial epithelial cells to CD61Â¯ cancer stem cells Research Paper

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 Research Paper

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer Research Paper

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer Research Paper

Sp1-mediated microRNA-182 expression regulates lung cancer progression Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells. Research Paper

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation Research Paper

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor Research Paper

Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo Research Paper

YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes. Research Paper

Tumor hypoxia enhances Non-Small Cell Lung Cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling Research Paper

Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine Research Paper

Targeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma Research Paper

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis Research Paper

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway Research Paper

Arsenic-induced sub-lethal stress reprograms human bronchial epithelial cells to CD61Â¯ cancer stem cells Research Paper

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 Research Paper

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer Research Paper

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer Research Paper

Sp1-mediated microRNA-182 expression regulates lung cancer progression Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function Research Paper