The Oncosearch | Oncotarget

Eribulin targets a ch-TOG-dependent directed migration of cancer cells Research Paper

Brice Chanez, Anthony GonÃ§alves, Ali Badache, Pascal Verdier-Pinard

Published Oct 19, 2015 · Vol. 6, No. 39 · pp. 41667-41678

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR Research Paper

Sue Ellen Verbrugge, Marjon Al, Yehuda G. Assaraf, Sarah Kammerer, Durga M.S.H. Chandrupatla, Richard Honeywell, Rene P.J. Musters, Elisa Giovannetti, Tom Oâ€™Toole, George L. Scheffer, David Krige, Tanja D. de Gruijl, Hans W.M. Niessen, Willem F. Lems, Pieternella A. Kramer, Rik J. Scheper, Jacqueline Cloos, Gert J. Ossenkoppele, Godefridus J. Peters, Gerrit Jansen

Published Oct 19, 2015 · Vol. 7, No. 5 · pp. 5240-5257

The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence Priority Research Paper

Keyata N. Thompson, Rebecca A. Whipple, Jennifer R. Yoon, Michael Lipsky, Monica S. Charpentier, Amanda E. Boggs, Kristi R. Chakrabarti, Lekhana Bhandary, Lindsay K. Hessler, Stuart S. Martin, Michele I. Vitolo

Published Oct 19, 2015 · Vol. 6, No. 34 · pp. 35231-35246

Association between serum uric acid and bone health in general population: a large and multicentre study Research Paper

Xianfeng Lin, Chenchen Zhao, An Qin, Dun Hong, Wenyue Liu, Kangmao Huang, Jian Mo, Hejun Yu, Shengjie Wu, Shunwu Fan

Published Oct 19, 2015 · Vol. 6, No. 34 · pp. 35395-35403

Epigenetic silencing of HIC1 promotes epithelial-mesenchymal transition and drives progression in esophageal squamous cell carcinoma Research Paper

Pei Li, Xiang Liu, Zi-Ming Dong, Zhi-Qiang Ling

Published Oct 17, 2015 · Vol. 6, No. 35 · pp. 38151-38165

Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth Research Paper

Surendra K. Shukla, Aneesha Dasgupta, Kamiya Mehla, Venugopal Gunda, Enza Vernucci, Joshua Souchek, Gennifer Goode, Ryan King, Anusha Mishra, Ibha Rai, Sangeetha Nagarajan, Nina V. Chaika, Fang Yu, Pankaj K. Singh

Published Oct 16, 2015 · Vol. 6, No. 38 · pp. 41146-41161

Wnt2 complements Wnt/Î²-catenin signaling in colorectal cancer Research Paper

Youn-Sang Jung, Sohee Jun, Sun Hye Lee, Amrish Sharma, Jae-Il Park

Published Oct 15, 2015 · Vol. 6, No. 35 · pp. 37257-37268

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition Priority Research Paper

Fiona K. Middleton, Miranda J. Patterson, Claire J. Elstob, Sarah Fordham, Ashleigh Herriott, Mark A. Wade, Aiste McCormick, Richard Edmondson, Felicity E.B. May, James M. Allan, John R. Pollard, Nicola J. Curtin

Published Oct 15, 2015 · Vol. 6, No. 32 · pp. 32396-32409

Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis Research Paper

Alexandra VÃ©tillard, Barbara JonchÃ¨re, Marie Moreau, Bertrand Toutain, CÃ©cile Henry, Simon Fontanel, Anne-Charlotte Bernard, Mario Campone, Catherine Guette, Olivier Coqueret

Published Oct 15, 2015 · Vol. 6, No. 41 · pp. 43342-43362

Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine Research Paper

Vivek Subbiah, Michael J. Wagner, Mary F. McGuire, Nawid M. Sarwari, Eswaran Devarajan, Valerae O. Lewis, Shanon Westin, Shumei Kato, Robert E. Brown, Pete Anderson

Published Oct 15, 2015 · Vol. 6, No. 38 · pp. 40642-40654

Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling Research Paper

Su-Ren Chen, Ji-Xin Tang, Jin-Mei Cheng, Jian Li, Cheng Jin, Xiao-Yu Li, Shou-Long Deng, Yan Zhang, Xiu-Xia Wang, Yi-Xun Liu

Published Oct 14, 2015 · Vol. 6, No. 35 · pp. 37012-37027

Polymorphisms involving gain or loss of CpG sites are significantly enriched in trait-associated SNPs Research Paper

Dan Zhou, Zhenli Li, Dan Yu, Ledong Wan, Yimin Zhu, Maode Lai, Dandan Zhang

Published Oct 14, 2015 · Vol. 6, No. 37 · pp. 39995-40004

miR-149 represses metastasis of hepatocellular carcinoma by targeting actin-regulatory proteins PPM1F Research Paper

Gang Luo, Ya-Ling Chao, Bo Tang, Bo-Sheng Li, Yu-Feng Xiao, Rui Xie, Shu-Ming Wang, Yu-Yun Wu, Hui Dong, Xiang-De Liu, Shi-Ming Yang

Published Oct 14, 2015 · Vol. 6, No. 35 · pp. 37808-37823

The role of Rak in the regulation of stability and function of BRCA1 Research Paper

Jung-Lye Kim, Geun-Hyoung Ha, Loredana Campo, Mitchell F. Denning, Tarun B. Patel, Clodia Osipo, Shiaw-Yih Lin, Eun-Kyoung Breuer

Published Oct 14, 2015 · Vol. 8, No. 49 · pp. 86799-86815

Clinicopathological and prognostic factors for long-term survival in Chinese patients with metastatic renal cell carcinoma treated with sorafenib: a single-center retrospective study Clinical Research Papers

Hai-Liang Zhang, Xiao-Jian Qin, Hong-Kai Wang, Wei-Jie Gu, Chun-Guang Ma, Guo-Hai Shi, Liang-Ping Zhou, Ding-Wei Ye

Published Oct 14, 2015 · Vol. 6, No. 34 · pp. 36870-36883

Increased metastasis with loss of E2F2 in Myc-driven tumors Research Paper

Inez Yuwanita, Danielle Barnes, Michael D. Monterey, Sandra Oâ€™Reilly, Eran R. Andrechek

Published Oct 13, 2015 · Vol. 6, No. 35 · pp. 38210-38224

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells Research Paper

Donatella Malanga, Carmela De Marco, Ilaria Guerriero, Fabiana Colelli, Nicola Rinaldo, Marianna Scrima, Teresa Mirante, Claudia De Vitis, Pietro Zoppoli, Michele Ceccarelli, Miriam Riccardi, Maria Ravo, Alessandro Weisz, Antonella Federico, Renato Franco, Gaetano Rocco, Rita Mancini, Antonia Rizzuto, Elio Gulletta, Gennaro Ciliberto, Giuseppe Viglietto

Published Oct 13, 2015 · Vol. 6, No. 40 · pp. 42667-42686

Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors Research Paper

Attje S. Hoekstra, Marieke A. de Graaff, Inge H. Briaire-de Bruijn, Cor Ras, Reza Maleki Seifar, Ivonne van Minderhout, Cees J. Cornelisse, Pancras C.W. Hogendoorn, Martijn H. Breuning, Johnny Suijker, Esther Korpershoek, Henricus P.M. Kunst, Norma Frizzell, Peter Devilee, Jean-Pierre Bayley, Judith V.M.G. BovÃ©e

Published Oct 12, 2015 · Vol. 6, No. 36 · pp. 38777-38788

Reciprocal feedback inhibition of the androgen receptor and PI3K as a novel therapy for castrate-sensitive and -resistant prostate cancer Research Paper

Wenqing Qi, Carla Morales, Laurence S. Cooke, Benny Johnson, Bradley Somer, Daruka Mahadevan

Published Oct 12, 2015 · Vol. 6, No. 39 · pp. 41976-41987

Viscoelastic and ultrastructural characteristics of whole blood and plasma in Alzheimer-type dementia, and the possible role of bacterial lipopolysaccharides (LPS) Research Paper

Janette Bester, Prashilla Soma, Douglas B. Kell, Etheresia Pretorius

Published Oct 10, 2015 · Vol. 6, No. 34 · pp. 35284-35303

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Eribulin targets a ch-TOG-dependent directed migration of cancer cells Research Paper

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR Research Paper

The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence Priority Research Paper

Association between serum uric acid and bone health in general population: a large and multicentre study Research Paper

Epigenetic silencing of HIC1 promotes epithelial-mesenchymal transition and drives progression in esophageal squamous cell carcinoma Research Paper

Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth Research Paper

Wnt2 complements Wnt/Î²-catenin signaling in colorectal cancer Research Paper

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition Priority Research Paper

Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis Research Paper

Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine Research Paper

Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling Research Paper

Polymorphisms involving gain or loss of CpG sites are significantly enriched in trait-associated SNPs Research Paper

miR-149 represses metastasis of hepatocellular carcinoma by targeting actin-regulatory proteins PPM1F Research Paper

The role of Rak in the regulation of stability and function of BRCA1 Research Paper

Clinicopathological and prognostic factors for long-term survival in Chinese patients with metastatic renal cell carcinoma treated with sorafenib: a single-center retrospective study Clinical Research Papers

Increased metastasis with loss of E2F2 in Myc-driven tumors Research Paper

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells Research Paper

Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors Research Paper

Reciprocal feedback inhibition of the androgen receptor and PI3K as a novel therapy for castrate-sensitive and -resistant prostate cancer Research Paper

Viscoelastic and ultrastructural characteristics of whole blood and plasma in Alzheimer-type dementia, and the possible role of bacterial lipopolysaccharides (LPS) Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Eribulin targets a ch-TOG-dependent directed migration of cancer cells Research Paper

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR Research Paper

The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence Priority Research Paper

Association between serum uric acid and bone health in general population: a large and multicentre study Research Paper

Epigenetic silencing of HIC1 promotes epithelial-mesenchymal transition and drives progression in esophageal squamous cell carcinoma Research Paper

Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth Research Paper

Wnt2 complements Wnt/Î²-catenin signaling in colorectal cancer Research Paper

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition Priority Research Paper

Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis Research Paper

Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine Research Paper

Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling Research Paper

Polymorphisms involving gain or loss of CpG sites are significantly enriched in trait-associated SNPs Research Paper

miR-149 represses metastasis of hepatocellular carcinoma by targeting actin-regulatory proteins PPM1F Research Paper

The role of Rak in the regulation of stability and function of BRCA1 Research Paper

Clinicopathological and prognostic factors for long-term survival in Chinese patients with metastatic renal cell carcinoma treated with sorafenib: a single-center retrospective study Clinical Research Papers

Increased metastasis with loss of E2F2 in Myc-driven tumors Research Paper

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells Research Paper

Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors Research Paper

Reciprocal feedback inhibition of the androgen receptor and PI3K as a novel therapy for castrate-sensitive and -resistant prostate cancer Research Paper

Viscoelastic and ultrastructural characteristics of whole blood and plasma in Alzheimer-type dementia, and the possible role of bacterial lipopolysaccharides (LPS) Research Paper