The Oncosearch | Oncotarget

Mesenchymal stem cells - the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists Review

Theia Minev, Shani Balbuena, Jaya Mini Gill, Francesco M. Marincola, Santosh Kesari, Feng Lin

Published Nov 9, 2024 · Vol. 15, No. 1 · pp. 793-805

Keywords: mesenchymal stem cells, genetic engineering, cancer immunotherapy, mesenchymal stem cell homing, stem cell delivery

The gut barrier as a gatekeeper in colorectal cancer treatment Review

Roy Hajjar, Carole Richard, Manuela M. Santos

Published Jul 20, 2024 · Vol. 15, No. 1 · pp. 562-572

Keywords: colorectal cancer, gut microbiome, gut barrier, colorectal surgery, anastomotic leak

Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism Research Perspective

Romain Villéger, Marina Chulkina, Randy C. Mifflin, Don W. Powell, Irina V. Pinchuk

Published Mar 28, 2023 · Vol. 14, No. 1 · pp. 377-381

Keywords: tumor microenvironment, colon cancer, inflammation, fibroblasts, IL-6

Retraction: Colon cancer-induced interleukin-35 inhibits beta-catenin-mediated pro-oncogenic activity Retraction

Yueqiang Jiang, Yanling Ma, RuiChao Li, JianHai Sun

Published Nov 26, 2022 · Vol. 13, No. 1 · pp. 1322-1322

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Masahiko Shibata, Kotaro Nanno, Daigo Yoshimori, Takahiro Nakajima, Makoto Takada, Takashi Yazawa, Kousaku Mimura, Norio Inoue, Takafumi Watanabe, Kazunoshin Tachibana, Satoshi Muto, Tomoyuki Momma, Yoshiyuki Suzuki, Koji Kono, Shungo Endo, Seiichi Takenoshita

Published Oct 25, 2022 · Vol. 13, No. 1 · pp. 1273-1285

Keywords: MDSC, immunosuppression, Treg, TAM, cancer

IL-33 promotes gastric tumour growth in concert with activation and recruitment of inflammatory myeloid cells Research Paper

Chau P. Tran, Michelle Scurr, Louise O’Connor, Jon N. Buzzelli, Garrett Z. Ng, Sharleen Chung Nien Chin, Lincon A. Stamp, Toshinari Minamoto, Andrew S. Giraud, Louise M. Judd, Philip Sutton, Trevelyan R. Menheniott

Published May 12, 2022 · Vol. 13, No. 1 · pp. 785-799

Keywords: IL-33, gastric cancer, tumorigenesis, mast cells, macrophages

Biomarkers and novel therapeutic approaches for diffuse large B-cell lymphoma in the era of precision medicine Review

Niraj Lodhi, Moe Tun, Poonam Nagpal, Arati A. Inamdar, Nehad M. Ayoub, Noor Siyam, Lucia Oton-Gonzalez, Angela Gerona, Dainelle Morris, Rana Sandhu, Kwangsun Stephen Suh

Published Oct 20, 2020 · Vol. 11, No. 44 · pp. 4045-4073

Keywords: DLBCL, diagnosis, R-CHOP, precision medicine, prognosis

Targeting an engineered cytokine with interleukin-2 and interleukin-15 activity to the neovasculature of solid tumors Research Paper

Michael R. Mortensen, Jacqueline Mock, Marco Bertolini, Marco Stringhini, Marco Catalano, Dario Neri

Published Oct 6, 2020 · Vol. 11, No. 44 · pp. 3972-3983

Keywords: immunotherapy, immunocytokines, EDB of fibronectin, antibody-cytokine fusion proteins, engineered cytokine

Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma Research Paper

Barbara Marengo, Elda Meta, Chiara Brullo, Chiara De Ciucis, Renata Colla, Andrea Speciale, Ombretta Garbarino, Olga Bruno, Cinzia Domenicotti

Published Aug 27, 2020 · Vol. 11, No. 37 · pp. 3459-3472

Keywords: tumor angiogenesis, neuroblastoma, vascular mimicry, pyrazolyl-urea derivatives, dihydro-imidazo-pyrazolyl-urea derivatives

A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo Research Paper

Tiziano Ongaro, Baptiste Gouyou, Marco Stringhini, Riccardo Corbellari, Dario Neri, Alessandra Villa

Published Aug 23, 2020 · Vol. 11, No. 41 · pp. 3698-3711

Keywords: tumor targeting, fibronectin, immunocytokines, interleukin-2, protein engineering

Association of functional IL16 polymorphisms with cancer and cardiovascular disease: a meta-analysis Meta-Analysis

Victor Hugo de Souza, Josiane Bazzo de Alencar, Bruna Tiaki Tiyo, Hugo Vicentin Alves, Evelyn Castillo Lima Vendramini, Ana Maria Sell, Jeane Eliete Laguila Visentainer

Published Aug 13, 2020 · Vol. 11, No. 36 · pp. 3405-3417

Keywords: cytokines, alleles, polymorphism, single nucleotide, inflammation

SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women Research Paper

Angel Núñez-Marrero, Nelly Arroyo, Lenin Godoy, Mohammad Zillur Rahman, Jaime L. Matta, Julie Dutil

Published Aug 5, 2020 · Vol. 11, No. 37 · pp. 3420-3431

Keywords: breast cancer, interleukin-12 (IL-12), IL-12 signaling, genetic association, single nucleotide polymorphisms

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Qiang Qiu, Mengyuan Li, Linyu Yang, Minghai Tang, Li Zheng, Fang Wang, Huandi Qiu, Cailing Liang, Ning Li, Dongni Yi, Yuyao Yi, Cong Pan, Shengyong Yang, Lijuan Chen, Yiguo Hu

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5993-6005

Keywords: glutaminase1, multiple myeloma, BPTES, cMYC/KRAS12V-transduced plasmacytoma, mouse model

Mechanism of internalization of MDA-7/IL-24 protein and its cognate receptors following ligand-receptor docking Research Paper

Anjan K. Pradhan, Praveen Bhoopathi, Sarmistha Talukdar, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Andrei I. Ivanov, Paul B. Fisher

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5103-5117

Keywords: MDA-7/Interleukin-24, Interleukin receptor, recombinant protein

MicroRNA-34a/IL-6R pathway as a potential therapeutic target for ovarian high-grade serous carcinoma Research Paper

Ryo Yokomizo, Nozomu Yanaihara, Noriko Yamaguchi, Misato Saito, Ayako Kawabata, Kazuaki Takahashi, Masataka Takenaka, Kyosuke Yamada, Jason Solomon Shapiro, Aikou Okamoto

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4880-4893

Keywords: ovarian high-grade serous carcinoma, miR-34a, IL-6R, STAT3, p53

Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis versus gluten-mediated inhibition in celiac disease Review

Luigi Maiuri, Valeria Raia, Mauro Piacentini, Antonella Tosco, Valeria Rachela Villella, Guido Kroemer

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4492-4500

Keywords: CFTR, cystic fibrosis, autophagy, celiac disease, transglutaminase 2

Endotoxin tolerance modulates TREG and TH17 lymphocytes protecting septic mice Research Paper

Mariana M.C. Andrade, Suely S.K. Ariga, Denise F. Barbeiro, Hermes V. Barbeiro, Rosangela N. Pimentel, Ricardo C. Petroni, Francisco G. Soriano

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3451-3461

Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model Research Paper

Rasha H. Dosh, Nicola Jordan-Mahy, Christopher Sammon, Christine Le Maitre

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3559-3575

Keywords: IL-1Ra deficient, inflammatory bowel disease, pro-inflammatory cytokines, matrix-degrading enzymes, intestinal enzymes

Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia Research Paper

Weiguo Han, Stephan J. Matissek, David A. Jackson, Brandon Sklavanitis, Sherine F. Elsawa

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3400-3407

Keywords: Waldenström macroglobulinemia, IL-6, Tocilizumab, tumor microenvironment

Intrinsic factor recognition promotes T helper 17/T helper 1 autoimmune gastric inflammation in patients with pernicious anemia Research Paper

Arianna Troilo, Alessia Grassi, Luisa Petrone, Fabio Cianchi, Marisa Benagiano, Chiara Della Bella, Nagaja Capitani, Jacopo Bitetti, Sofia D’Elios, Simona Tapinassi, Annalisa Azzurri, Heba Alnwaisri, Jacopo Romagnoli, Nicola Bizzaro, Mathijs Bergman, Cosima Tatiana Baldari, Mario Milco D’Elios

Published Apr 23, 2019 · Vol. 10, No. 30 · pp. 2921-2929

Keywords: intrinsic factor, interferon-gamma, interleukin-17, pernicious anemia, atrophic gastritis

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Mesenchymal stem cells - the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists Review

The gut barrier as a gatekeeper in colorectal cancer treatment Review

Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism Research Perspective

Retraction: Colon cancer-induced interleukin-35 inhibits beta-catenin-mediated pro-oncogenic activity Retraction

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

IL-33 promotes gastric tumour growth in concert with activation and recruitment of inflammatory myeloid cells Research Paper

Biomarkers and novel therapeutic approaches for diffuse large B-cell lymphoma in the era of precision medicine Review

Targeting an engineered cytokine with interleukin-2 and interleukin-15 activity to the neovasculature of solid tumors Research Paper

Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma Research Paper

A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo Research Paper

Association of functional IL16 polymorphisms with cancer and cardiovascular disease: a meta-analysis Meta-Analysis

SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women Research Paper

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Mechanism of internalization of MDA-7/IL-24 protein and its cognate receptors following ligand-receptor docking Research Paper

MicroRNA-34a/IL-6R pathway as a potential therapeutic target for ovarian high-grade serous carcinoma Research Paper

Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis versus gluten-mediated inhibition in celiac disease Review

Endotoxin tolerance modulates TREG and TH17 lymphocytes protecting septic mice Research Paper

Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model Research Paper

Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia Research Paper

Intrinsic factor recognition promotes T helper 17/T helper 1 autoimmune gastric inflammation in patients with pernicious anemia Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Mesenchymal stem cells - the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists Review

The gut barrier as a gatekeeper in colorectal cancer treatment Review

Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism Research Perspective

Retraction: Colon cancer-induced interleukin-35 inhibits beta-catenin-mediated pro-oncogenic activity Retraction

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

IL-33 promotes gastric tumour growth in concert with activation and recruitment of inflammatory myeloid cells Research Paper

Biomarkers and novel therapeutic approaches for diffuse large B-cell lymphoma in the era of precision medicine Review

Targeting an engineered cytokine with interleukin-2 and interleukin-15 activity to the neovasculature of solid tumors Research Paper

Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma Research Paper

A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo Research Paper

Association of functional IL16 polymorphisms with cancer and cardiovascular disease: a meta-analysis Meta-Analysis

SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women Research Paper

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Mechanism of internalization of MDA-7/IL-24 protein and its cognate receptors following ligand-receptor docking Research Paper

MicroRNA-34a/IL-6R pathway as a potential therapeutic target for ovarian high-grade serous carcinoma Research Paper

Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis versus gluten-mediated inhibition in celiac disease Review

Endotoxin tolerance modulates TREG and TH17 lymphocytes protecting septic mice Research Paper

Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model Research Paper

Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia Research Paper

Intrinsic factor recognition promotes T helper 17/T helper 1 autoimmune gastric inflammation in patients with pernicious anemia Research Paper