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Current perspectives between metabolic syndrome and cancer Review

Carla Micucci, Debora Valli, Giulia Matacchione, Alfonso Catalano

Published Mar 24, 2016 · Vol. 7, No. 25 · pp. 38959-38972

Towards understanding the lifespan extension by reduced insulin signaling: bioinformatics analysis of DAF-16/FOXO direct targets in Caenorhabditis elegans Research Paper

Yan-Hui Li, Gai-Gai Zhang

Published Mar 24, 2016 · Vol. 7, No. 15 · pp. 19185-19192

Repurposing metformin for cancer treatment: current clinical studies Review

Young Kwang Chae, Ayush Arya, Mary-Kate Malecek, Daniel Sanghoon Shin, Benedito Carneiro, Sunandana Chandra, Jason Kaplan, Aparna Kalyan, Jessica K. Altman, Leonidas Platanias, Francis Giles

Published Mar 19, 2016 · Vol. 7, No. 26 · pp. 40767-40780

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse Research Paper

Sharon E. Mitchell, Camille Delville, Penelope Konstantopedos, Davina Derous, Cara L. Green, Yingchun Wang, Jing-Dong J. Han, Daniel E.L. Promislow, Alex Douglas, Luonan Chen, David Lusseau, John R. Speakman

Published Mar 17, 2016 · Vol. 7, No. 15 · pp. 19147-19170

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Ji Hyun Park, Yun Jung Choi, Seon Ye Kim, Jung-Eun Lee, Ki Jung Sung, Sojung Park, Woo Sung Kim, Joon Seon Song, Chang-Min Choi, Young Hoon Sung, Jin Kyung Rho, Jae Cheol Lee

Published Mar 9, 2016 · Vol. 7, No. 16 · pp. 22005-22015

Insulin receptor substrate 1 is a substrate of the Pim protein kinases Research Paper

Jin H. Song, Sathish K. R. Padi, Libia A. Luevano, Mark D. Minden, Daniel J. DeAngelo, Gary Hardiman, Lauren E. Ball, Noel A. Warfel, Andrew S. Kraft

Published Mar 4, 2016 · Vol. 7, No. 15 · pp. 20152-20165

Western diet enhances benzo(a)pyrene-induced colon tumorigenesis in a polyposis in rat coli (PIRC) rat model of colon cancer Research Paper

Kelly L. Harris, Stephanie R. Pulliam, Emmanuel Okoro, Zhongmao Guo, Mary K. Washington, Samuel E. Adunyah, James M. Amos-Landgraf, Aramandla Ramesh

Published Mar 3, 2016 · Vol. 7, No. 20 · pp. 28947-28960

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model Research Paper

MarÃa E. CabalÃ©n, MarÃa F. Cabral, Liliana M. Sanmarco, Marta C. Andrada, Luisina I. Onofrio, NicolÃ¡s E. Ponce, MarÃa P. Aoki, Susana Gea, Roxana C. Cano

Published Feb 23, 2016 · Vol. 7, No. 12 · pp. 13400-13415

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models Research Paper

Jeong Youp Park, Jin Young Lee, Yong Zhang, Robert M. Hoffman, Michael Bouvet

Published Feb 22, 2016 · Vol. 7, No. 14 · pp. 18262-18268

Transcriptomic analysis of stage 1 versus advanced adult granulosa cell tumors Research Paper

Maria Alexiadis, Simon Chu, Dilys Leung, Jodee A. Gould, Tom Jobling, Peter J. Fuller

Published Feb 16, 2016 · Vol. 7, No. 12 · pp. 14207-14219

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor Research Paper

Sen Liu, Qiuyang Zhang, Chong Chen, Dongxia Ge, Yine Qu, Rongyi Chen, Yi-Ming Fan, Nan Li, Wendell W. Tang, Wensheng Zhang, Kun Zhang, Alun R. Wang, Brian G. Rowan, Steven M. Hill, Oliver Sartor, Asim B. Abdel-Mageed, Leann Myers, Qishan Lin, Zongbing You

Published Feb 10, 2016 · Vol. 7, No. 12 · pp. 13651-13666

Sodium alginate prevents progression of non-alcoholic steatohepatitis and liver carcinogenesis in obese and diabetic mice Research Paper

Tsuneyuki Miyazaki, Yohei Shirakami, Masaya Kubota, Takayasu Ideta, Takahiro Kochi, Hiroyasu Sakai, Takuji Tanaka, Hisataka Moriwaki, Masahito Shimizu

Published Feb 8, 2016 · Vol. 7, No. 9 · pp. 10448-10458

IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2^V617F-positive myeloproliferative neoplasms Research Paper

Paula de Melo Campos, JoÃ£o A. Machado-Neto, Christopher A. Eide, Samantha L. Savage, Renata Scopim-Ribeiro, Adriana da Silva Souza Duarte, Patricia Favaro, Irene Lorand-Metze, Fernando F. Costa, Cristina E. Tognon, Brian J. Druker, Sara T. Olalla Saad, Fabiola Traina

Published Jan 9, 2016 · Vol. 7, No. 6 · pp. 6948-6959

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma Research Paper

Claudia Pivonello, Mariarosaria Negri, Maria Cristina De Martino, Maria Napolitano, Cristina de Angelis, Donatella Paola Provvisiero, Gaia Cuomo, Renata Simona Auriemma, Chiara Simeoli, Francesco Izzo, Annamaria Colao, Leo J. Hofland, Rosario Pivonello

Published Jan 7, 2016 · Vol. 7, No. 9 · pp. 9718-9731

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population Research Paper

Ning Li, Huaichao Luo, Xiaoqi Liu, Shi Ma, He Lin, Rong Chen, Fang Hao, Dingding Zhang

Published Dec 16, 2015 · Vol. 7, No. 1 · pp. 23-32

MicroRNA-1225-5p inhibits proliferation and metastasis of gastric carcinoma through repressing insulin receptor substrate-1 and activation of Î²-catenin signaling Research Paper

Haiyin Zheng, Fuxing Zhang, Xinjian Lin, Changming Huang, Yiqin Zhang, Yun Li, Jianyin Lin, Wannan Chen, Xu Lin

Published Dec 14, 2015 · Vol. 7, No. 4 · pp. 4647-4663

IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway Research Paper

Roberta MatÃ, Chiara Palladino, Maria Luisa Nicolosi, Anna Rita Lo Presti, Roberta Malaguarnera, Marco Ragusa, Daniela Sciortino, Andrea Morrione, Marcello Maggiolini, Veronica Vella, Antonino Belfiore

Published Dec 9, 2015 · Vol. 7, No. 7 · pp. 7683-7700

Prohibitin overexpression improves myocardial function in diabetic cardiomyopathy Research Paper

Wen-qian Dong, Min Chao, Qing-hua Lu, Wei-li Chai, Wei Zhang, Xue-ying Chen, Er-shun Liang, Ling-bo Wang, Hong-liang Tian, Yu-guo Chen, Ming-xiang Zhang

Published Nov 25, 2015 · Vol. 7, No. 1 · pp. 66-80

Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer Research Paper

Juan Zhou, Jinjing Wang, Yunyun Zeng, Xi Zhang, Qiaoting Hu, Jihua Zheng, Bei Chen, Bo Xie, Wei-Min Zhang

Published Nov 5, 2015 · Vol. 6, No. 42 · pp. 44332-44345

Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans Research Paper

Neeraj Kumar, Vaibhav Jain, Anupama Singh, Urmila Jagtap, Sonia Verma, Arnab Mukhopadhyay

Published Nov 2, 2015 · Vol. 6, No. 39 · pp. 41418-41433

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Current perspectives between metabolic syndrome and cancer Review

Towards understanding the lifespan extension by reduced insulin signaling: bioinformatics analysis of DAF-16/FOXO direct targets in Caenorhabditis elegans Research Paper

Repurposing metformin for cancer treatment: current clinical studies Review

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse Research Paper

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Insulin receptor substrate 1 is a substrate of the Pim protein kinases Research Paper

Western diet enhances benzo(a)pyrene-induced colon tumorigenesis in a polyposis in rat coli (PIRC) rat model of colon cancer Research Paper

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model Research Paper

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models Research Paper

Transcriptomic analysis of stage 1 versus advanced adult granulosa cell tumors Research Paper

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor Research Paper

Sodium alginate prevents progression of non-alcoholic steatohepatitis and liver carcinogenesis in obese and diabetic mice Research Paper

IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2^V617F-positive myeloproliferative neoplasms Research Paper

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma Research Paper

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population Research Paper

MicroRNA-1225-5p inhibits proliferation and metastasis of gastric carcinoma through repressing insulin receptor substrate-1 and activation of Î²-catenin signaling Research Paper

IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway Research Paper

Prohibitin overexpression improves myocardial function in diabetic cardiomyopathy Research Paper

Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer Research Paper

Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Current perspectives between metabolic syndrome and cancer Review

Towards understanding the lifespan extension by reduced insulin signaling: bioinformatics analysis of DAF-16/FOXO direct targets in Caenorhabditis elegans Research Paper

Repurposing metformin for cancer treatment: current clinical studies Review

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse Research Paper

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Insulin receptor substrate 1 is a substrate of the Pim protein kinases Research Paper

Western diet enhances benzo(a)pyrene-induced colon tumorigenesis in a polyposis in rat coli (PIRC) rat model of colon cancer Research Paper

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model Research Paper

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models Research Paper

Transcriptomic analysis of stage 1 versus advanced adult granulosa cell tumors Research Paper

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor Research Paper

Sodium alginate prevents progression of non-alcoholic steatohepatitis and liver carcinogenesis in obese and diabetic mice Research Paper

IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2V617F-positive myeloproliferative neoplasms Research Paper

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma Research Paper

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population Research Paper

MicroRNA-1225-5p inhibits proliferation and metastasis of gastric carcinoma through repressing insulin receptor substrate-1 and activation of Î²-catenin signaling Research Paper

IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway Research Paper

Prohibitin overexpression improves myocardial function in diabetic cardiomyopathy Research Paper

Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer Research Paper

Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans Research Paper

IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2^V617F-positive myeloproliferative neoplasms Research Paper