The Oncosearch | Oncotarget

Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine Research Paper

Masamichi Hayashi, Heike Bernert, Luciane Tsukamoto Kagohara, Leonel Maldonado, Mariana Brait, Mark Schoenberg, Trinity Bivalacqua, George J. Netto, Wayne Koch, David Sidransky, Mohammad O. Hoque

Published May 7, 2014 · Vol. 5, No. 10 · pp. 3350-3361

An updated overview of HPV-associated head and neck carcinomas Review

Apostolos Zaravinos

Published May 1, 2014 · Vol. 5, No. 12 · pp. 3956-3969

NM23-H1 expression of head and neck squamous cell carcinoma in association with the response to cisplatin treatment Research Paper

Yi-Fen Wang, Chun-Ju Chang, Jen-Hwey Chiu, Chin-Ping Lin, Wing-Yin Li, Shyue-Yih Chang, Pen-Yuan Chu, Shyh-Kuan Tai, Yu-Jen Chen

Published Apr 18, 2014 · Vol. 5, No. 17 · pp. 7392-7405

Tumor cell apoptosis mediated by cytoplasmic ING1 is associated with improved survival in oral squamous cell carcinoma patients. Research Paper

Pinaki Bose, Satbir S. Thakur, Nigel T. Brockton, Alexander C. Klimowicz, Elizabeth Kornaga, Steven C. Nakoneshny, Karl T. Riabowol, Joseph C. Dort

Published Apr 17, 2014 · Vol. 5, No. 10 · pp. 3210-3219

Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior Research Paper

Chih-Yen Chien, Hsin-Ting Tsai, Li-Jen Su, Hui-Ching Chuang, Li-Yen Shiu, Chao-Cheng Huang, Fu-Min Fang, Chun-Chieh Yu, Huei-Ting Su, Chang-Han Chen

Published Apr 11, 2014 · Vol. 5, No. 8 · pp. 2243-2262

Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress Research Paper

Yu-Chin Lin, Meng-Hsuan Wu, Tzu-Tang Wei, Yun-Chieh Lin, Wen-Chih Huang, Liang-Yu Huang, Yi-Ting Lin, Ching-Chow Chen

Published Jan 7, 2014 · Vol. 5, No. 1 · pp. 298-308

Keywords: AMPK, ER stress, EGFR, dasatinib, PDK4

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

Zhongwu li, Yanling Wang, Jing Qiu, Qiang Li, Chunping Yuan, Wei Zhang, Dongmiao Wang, Jinhai Ye, Hongbin Jiang, Jianrong Yang, Jie Cheng

Published Dec 7, 2013 · Vol. 4, No. 12 · pp. 2532-2549

Keywords: tongue squamous cell carcinoma, polycomb complex, EZH2, DZNep

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma Research Paper

Hsin-Pai Li, Chen-Ching Peng, I-Che Chung, Mei-Yuan Huang, Shao-Tung Huang, Chia-Chun Chen, Kai-Ping Chang, Cheng-Lung Hsu, Yu-Sun Chang

Published Nov 4, 2013 · Vol. 4, No. 11 · pp. 2154-2165

Keywords: HOXA2, DNA methylation, NPC, MMP9

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma Research Paper

Jennifer K Wolter, Nikolaus E Wolter, Alvaro Blanch, Teresa Partridge, Lynn Cheng, Daniel A. Morgenstern, Monika Podkowa, David R. Kaplan, Meredith S. Irwin

Published Nov 4, 2013 · Vol. 5, No. 1 · pp. 161-172

Keywords: neuroblastoma, propranolol, beta-adrenergic receptor, p53, p73

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer Research Paper

He Shen, Carl D. Morrison, Jianmin Zhang, Willie Underwood III, Nuo Yang, Costa Frangou, Kevin Eng, Karen Head, Roni J. Bollag, Sravan K. Kavuri, Amyn M. Rojiani, Yingwei Li, Li Yan, Annette Hill, Anna Woloszynska-Read, Jianmin Wang, Song Liu, Donald L. Trump, Candace S. Johnson

Published Oct 29, 2013 · Vol. 4, No. 11 · pp. 2124-2134

Keywords: bladder cancer, chromosome 6p22, FISH, outcome, survival

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers Research Paper

Shruti Desai, Minming Ding, Bin Wang, Zhimin Lu, Qi Zhao, Kenna Shaw, W K Alfred Yung, John N Weinstein, Ming Tan, Jun Yao

Published Aug 7, 2013 · Vol. 5, No. 18 · pp. 8202-8210

Keywords: PKM2, alternative splicing, DNA methylation

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a* Research Paper

Xiaoli Wu, Mihir K. Bhayani, Cristina T. Dodge, Milena S. Nicoloso, Yunyun Chen, Xiaofeng Yan, Makoto Adachi, Ligy Thomas, Chad E. Galer, Tilahun Jiffar, Curtis R. Pickering, Michael E. Kupferman, Jeffrey N. Myers, George A. Calin, Stephen Y. Lai

Published Aug 6, 2013 · Vol. 4, No. 9 · pp. 1388-1398

Keywords: miRNA EGFR AKT1 mTOR miRNA-27a* miRNA-27a-5p

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population Research Paper

Jennifer Wheler, Gerald Falchook, Apostolia M. Tsimberidou, David Hong, Aung Naing, Sarina Piha-Paul, Su S. Chen, John Heymach, Siqing Fu, Su S. Chen, Bettzy Stephen, Jansina Y. Fok, Filip Janku, Razelle Kurzrock

Published Jun 4, 2013 · Vol. 4, No. 5 · pp. 772-784

Keywords: EGFR mutation, EGFR wild-type, non-small cell lung cancer, phase I trials, resistance, squamous cell

Exomic Sequencing of Four Rare Central Nervous System Tumor Types Research Paper

Chetan Bettegowda, Nishant Agrawal, Yuchen Jiao, Yuxuan Wang, Laura D. Wood, Fausto J. Rodriguez, Ralph H. Hruban, Gary L. Gallia, Zev A. Binder, Callen J. Riggins, Vafi Salmasi, Gregory J. Riggins, Zachary J. Reitman, Ahmed Rasheed, Stephen Keir, Sueli Shinjo, Suely Marie, Roger McLendon, George Jallo, Bert Vogelstein, Darrell Bigner, Hai Yan, Kenneth W. Kinzler, Nickolas Papadopoulos

Published Apr 6, 2013 · Vol. 4, No. 4 · pp. 572-583

Keywords: CNS tumors, PXA, GBM, ependymoma, exomic sequencing, BRAF, mTOR

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Up-regulates Interleukin-6 in Cancer Cells and Induces Subsequent Development of Interstitial Pneumonia Research Paper

Yukari Ishiguro, Hitoshi Ishiguro, Hiroshi Miyamoto

Published Mar 31, 2013 · Vol. 4, No. 4 · pp. 550-559

Keywords: fibrosis, EGFR-TKI, IL-6, cytokine, side-effect

Lin28b Promotes Head and Neck Cancer Progression via Modulation of the Insulin-Like Growth Factor Survival Pathway Research Paper

Nehad M Alajez, Wei Shi, Dennis Wong, Michelle Lenarduzzi, John Waldron, Ilan Weinreb, Fei-Fei Liu

Published Dec 29, 2012 · Vol. 3, No. 12 · pp. 1641-1652

Keywords: Lin28b, microRNA, Let-7, HNC, IGF

Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma Research Paper

Takashi Kinoshita, Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Hideki Enokida, Hirofumi Yoshino, Takeshi Yamasaki, Hideo Hidaka, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki

Published Nov 7, 2012 · Vol. 3, No. 11 · pp. 1386-1400

Keywords: microRNA, miR-218, tumor suppressor, focal adhesion, laminin-332, head and neck squamous cell carcinoma

microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers Review

Nijiro Nohata, Toyoyuki Hanazawa, Hideki Enokida, Naohiko Seki

Published Feb 4, 2012 · Vol. 3, No. 1 · pp. 9-21

Keywords: cancer, miRNA, miR-1, miR-133a, miR-133b, miR-206

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer Research Paper

Roland H. Stauber, Shirley K. Knauer, Negusse Habtemichael, Carolin Bier, Britta Unruhe, Simona Weisheit, Stephanie Spange, Frank Nonnenmacher, Verena Fetz, Torsten Ginter, Sigrid Reichardt, Claus Liebmann, GÃ¼nter Schneider, Oliver H. KrÃ¤mer

Published Jan 28, 2012 · Vol. 3, No. 1 · pp. 31-43

Keywords: apoptosis, BH3-only protein, chemotherapy, hydroxyurea, oral cancer, therapy resistance, tumor xenograft, valproic acid

Resistance to EGFR inhibitors: Molecular determinants and the enigma of head and neck cancer Editorial Comments

Luc G.T. Morris, Timothy A. Chan

Published Dec 31, 2011 · Vol. 2, No. 12 · pp. 894-895

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine Research Paper

An updated overview of HPV-associated head and neck carcinomas Review

NM23-H1 expression of head and neck squamous cell carcinoma in association with the response to cisplatin treatment Research Paper

Tumor cell apoptosis mediated by cytoplasmic ING1 is associated with improved survival in oral squamous cell carcinoma patients. Research Paper

Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior Research Paper

Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress Research Paper

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma Research Paper

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma Research Paper

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer Research Paper

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers Research Paper

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a* Research Paper

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population Research Paper

Exomic Sequencing of Four Rare Central Nervous System Tumor Types Research Paper

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Up-regulates Interleukin-6 in Cancer Cells and Induces Subsequent Development of Interstitial Pneumonia Research Paper

Lin28b Promotes Head and Neck Cancer Progression via Modulation of the Insulin-Like Growth Factor Survival Pathway Research Paper

Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma Research Paper

microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers Review

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer Research Paper

Resistance to EGFR inhibitors: Molecular determinants and the enigma of head and neck cancer Editorial Comments

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine Research Paper

An updated overview of HPV-associated head and neck carcinomas Review

NM23-H1 expression of head and neck squamous cell carcinoma in association with the response to cisplatin treatment Research Paper

Tumor cell apoptosis mediated by cytoplasmic ING1 is associated with improved survival in oral squamous cell carcinoma patients. Research Paper

Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior Research Paper

Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress Research Paper

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma Research Paper

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma Research Paper

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer Research Paper

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers Research Paper

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a* Research Paper

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population Research Paper

Exomic Sequencing of Four Rare Central Nervous System Tumor Types Research Paper

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Up-regulates Interleukin-6 in Cancer Cells and Induces Subsequent Development of Interstitial Pneumonia Research Paper

Lin28b Promotes Head and Neck Cancer Progression via Modulation of the Insulin-Like Growth Factor Survival Pathway Research Paper

Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma Research Paper

microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers Review

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer Research Paper

Resistance to EGFR inhibitors: Molecular determinants and the enigma of head and neck cancer Editorial Comments