The Oncosearch | Oncotarget

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness Research Paper

Helge Siemens, Rene Jackstadt, Markus Kaller, Heiko Hermeking

Published Aug 6, 2013 · Vol. 4, No. 9 · pp. 1399-1415

Keywords: p53, miR-34, c-Kit, migration, chemoresistance, stemness

Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5 Research Paper

Xu Di, Guofeng Zhang, Yaqin Zhang, Kazuyo Takeda, Leslie A. Rivera Rosado, Baolin Zhang

Published Jul 27, 2013 · Vol. 4, No. 9 · pp. 1349-1364

Keywords: TRAIL resistance, basal autophagosomes, death receptors, cell surface expression

A Tumor initiating cell-enriched prognostic signature for HER2+:ERÎ±- breast cancer; rationale, new features, controversies and future directions Research Perspective

Jeff C. Liu, Sean E. Egan, Eldad Zacksenhaus

Published Jul 26, 2013 · Vol. 4, No. 8 · pp. 1317-1328

Keywords: Breast Cancer, HER2, prognostic signature, tumor-initiating cells

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. Research Paper

Rocky Cipriano, Kristy L.S. Miskimen, Benjamin L. Bryson, Chase R. Foy, Courtney A. Bartel, Mark W Jackson

Published May 11, 2013 · Vol. 4, No. 5 · pp. 729-738

Keywords: FAM83B, transformation, drug resistance, CRAF, PI3K

Linked-In: Design and Efficacy of Antibody Drug Conjugates in Oncology Review

Jonathan Feld, Stefan K. Barta, Carolina Schinke, Ira Braunschweig, Yiyu Zhou, Amit K. Verma

Published Mar 26, 2013 · Vol. 4, No. 3 · pp. 397-412

Keywords: antibody drug conjugates, oncotargets, immunotoxins

Tumorigenic potential of circulating prostate tumor cells Research Paper

Filipe LF. Carvalho, Brian W. Simons, Emmanuel S. Antonarakis, Zeshaan Rasheed, Nora Douglas, Daniela Villegas, William Matsui, David M. Berman

Published Mar 5, 2013 · Vol. 4, No. 3 · pp. 413-421

Keywords: Circulating tumor cells, EpCAM, prostate cancer, prostate-specific antigen, TRAMP mouse

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity Research Paper

Swapna Asuthkar, Kiran Kumar Velpula, Chandramu Chetty, Bharathi Gorantla, Jasti S. Rao

Published Nov 16, 2012 · Vol. 3, No. 11 · pp. 1439-1454

Keywords: Matrix metalloproteinase-9 (MMP-9), microRNA-211 (miR-211), Cancer Stem Cells (CSC), Ionizing radiation (IR) and Temozolomide (Tem)

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels Research Paper

Daniela Bressanin, Camilla Evangelisti, Francesca Ricci, Giovanna Tabellini, Francesca Chiarini, Pier Luigi Tazzari, Fraia Melchionda, Francesca Buontempo, Pasqualepaolo Pagliaro, Andrea Pession, James A McCubrey, Alberto M. Martelli

Published Aug 9, 2012 · Vol. 3, No. 8 · pp. 811-823

Keywords: acute leukemia, targeted therapy, signal transduction modulators, PI3K/PDK1, vertical inhibition

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment Review

Alberto M. Martelli, Francesca Chiarini, Camilla Evangelisti, Alessandra Cappellini, Francesca Buontempo, Daniela Bressanin, Milena Fini, James A. McCubrey

Published May 4, 2012 · Vol. 3, No. 4 · pp. 371-394

Keywords: apoptosis, leukemia initiating cells, mRNA translation, PI3K/Akt/mTOR, targeted therapy

Proteomic Signatures of the Desmoplastic Invasion Front Reveal Collagen Type XII as a Marker of Myofibroblastic Differentiation During Colorectal Cancer Metastasis Research Paper

George S. Karagiannis, Constantina Petraki, Ioannis Prassas, Punit Saraon, Natasha Musrap, Apostolos Dimitromanolakis, Eleftherios P. Diamandis

Published Mar 8, 2012 · Vol. 3, No. 3 · pp. 267-285

Keywords: Colorectal cancer, Cancer-associated fibroblasts, Desmoplasia, Proteomics, Secretome, Collagen type XII

AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications. Research Perspective

Leonidas Platanias, Eliza Vakana

Published Dec 31, 2011 · Vol. 2, No. 12 · pp. 1322-1328

Keywords: AMPK, mTOR, leukemia, BCR-ABL

Metformin: Multi-faceted protection against cancer Review

Sonia Del Barco, Alejandro Vazquez-Martin, SÃlvia CufÃ, Cristina Oliveras-Ferraros, Joaquim Bosch-Barrera, Jorge Joven, BegoÃ±a Martin-Castillo, Javier A Menendez

Published Dec 24, 2011 · Vol. 2, No. 12 · pp. 896-917

Keywords: Diabetes, cancer, metformin, cancer stem cells, senescence

Disruption of p16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in vivo Research Paper

Wanglong Qiu, Fikret Sahin, Christine Iacobuzio-Donahue, Dario Garcia-Carracedo, Wendy Wang, Chia-Yu Kuo, Doris Chen, Dan Arking, Andrew Lowy, Ralph Hruban, Helen Remotti, Gloria H. Su

Published Nov 23, 2011 · Vol. 2, No. 11 · pp. 862-873

Keywords: p16, LOH at Kras, pancreatic cancer, metastasis, mouse model, conditional knock-out, target therapy, PanIN, Pancreatic ductal adenocarcinoma, tumor-suppressor gene.

ARID2: A new tumor suppressor gene in hepatocellular carcinoma Research Perspective

Hong Zhao, Jian wang, Yongqing Han, Zhen Huang, Jianming Ying, Xinyu Bi, Jianjun Zhao, Yi Fang, Haitao Zhou, Jianguo Zhou, Zhiyu Li, Yefan Zhang, Xue Yang, Tao Yan, Linfang Wang, Michael S Torbenson, Jianqiang Cai

Published Nov 16, 2011 · Vol. 2, No. 11 · pp. 886-891

Keywords: Hepatocellular Carcinoma, Hepatitis C Virus, ARID2, Tumor Suppressor, Interferon

Systemic use of tumor necrosis factor alpha as an anticancer agent Review

Nicholas J. Roberts, Shibin Zhou, Luis A. Diaz, Matthias Holdhoff

Published Oct 27, 2011 · Vol. 2, No. 10 · pp. 739-751

Keywords: TNF-Î±, systemic, therapy

The beating heart of melanomas: a minor subset of cancer cells sustains tumor growth Research Perspective

Patrick Schmidt, Hinrich Abken

Published Apr 10, 2011 · Vol. 2, No. 4 · pp. 313-320

Keywords: melanoma, cancer stem cell, adoptive cell therapy

IgH gene rearrangements as plasma biomarkers in Non-Hodgkin's Lymphoma patients Research Paper

Jian He, Jian Wu, Yuchen Jiao, Nina Wagner-Johnston, Richard F. Ambinder, Luis A. Diaz, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos

Published Mar 8, 2011 · Vol. 2, No. 3 · pp. 178-185

The Challenge for Gene Therapy: Innate Immune Response to Adenoviruses Review

Bart Thaci, Ilya V. Ulasov, Derek V. Wainwright, Maciej S. Lesniak

Published Mar 5, 2011 · Vol. 2, No. 3 · pp. 113-121

Keywords: Adenovirus, interferon, interleukin-1, innate immune response

Antiangiogenic agents in advanced gastrointestinal malignancies: past, present and a novel future Review

Karen Mulder, Sheryl Koski, Andrew Scarfe, Quincy Chu, Karen King, Jennifer Spratlin

Published Oct 15, 2010 · Vol. 1, No. 7 · pp. 515-529

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism Research Paper

Stuart A Rushworth, Lyubov Zaitseva, Susana Langa, Kristian M Bowles, David J MacEwan

Published Sep 13, 2010 · Vol. 1, No. 5 · pp. 359-366

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Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness Research Paper

Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5 Research Paper

A Tumor initiating cell-enriched prognostic signature for HER2+:ERÎ±- breast cancer; rationale, new features, controversies and future directions Research Perspective

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. Research Paper

Linked-In: Design and Efficacy of Antibody Drug Conjugates in Oncology Review

Tumorigenic potential of circulating prostate tumor cells Research Paper

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity Research Paper

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels Research Paper

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment Review

Proteomic Signatures of the Desmoplastic Invasion Front Reveal Collagen Type XII as a Marker of Myofibroblastic Differentiation During Colorectal Cancer Metastasis Research Paper

AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications. Research Perspective

Metformin: Multi-faceted protection against cancer Review

Disruption of p16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in vivo Research Paper

ARID2: A new tumor suppressor gene in hepatocellular carcinoma Research Perspective

Systemic use of tumor necrosis factor alpha as an anticancer agent Review

The beating heart of melanomas: a minor subset of cancer cells sustains tumor growth Research Perspective

IgH gene rearrangements as plasma biomarkers in Non-Hodgkin's Lymphoma patients Research Paper

The Challenge for Gene Therapy: Innate Immune Response to Adenoviruses Review

Antiangiogenic agents in advanced gastrointestinal malignancies: past, present and a novel future Review

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness Research Paper

Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5 Research Paper

A Tumor initiating cell-enriched prognostic signature for HER2+:ERÎ±- breast cancer; rationale, new features, controversies and future directions Research Perspective

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. Research Paper

Linked-In: Design and Efficacy of Antibody Drug Conjugates in Oncology Review

Tumorigenic potential of circulating prostate tumor cells Research Paper

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity Research Paper

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels Research Paper

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment Review

Proteomic Signatures of the Desmoplastic Invasion Front Reveal Collagen Type XII as a Marker of Myofibroblastic Differentiation During Colorectal Cancer Metastasis Research Paper

AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications. Research Perspective

Metformin: Multi-faceted protection against cancer Review

Disruption of p16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in vivo Research Paper

ARID2: A new tumor suppressor gene in hepatocellular carcinoma Research Perspective

Systemic use of tumor necrosis factor alpha as an anticancer agent Review

The beating heart of melanomas: a minor subset of cancer cells sustains tumor growth Research Perspective

IgH gene rearrangements as plasma biomarkers in Non-Hodgkin's Lymphoma patients Research Paper

The Challenge for Gene Therapy: Innate Immune Response to Adenoviruses Review

Antiangiogenic agents in advanced gastrointestinal malignancies: past, present and a novel future Review

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism Research Paper