The Oncosearch | Oncotarget

Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity Research Paper

Maxim A. Shevtsov, Elena Y. Komarova, Darya A. Meshalkina, Natalia V. Bychkova, Nikolai D. Aksenov, Sergey V. Abkin, Boris A. Margulis, Irina V. Guzhova

Published Mar 22, 2014 · Vol. 5, No. 10 · pp. 3101-3114

17Î²-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells Research Paper

Paul K. Wright, Sarah Bowen Jones, Nicholas Ardern, Rebecca Ward, Robert B. Clarke, Federica Sotgia, Michael P. Lisanti, Goran Landberg, Rebecca Lamb

Published Mar 15, 2014 · Vol. 5, No. 10 · pp. 3055-3065

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style Research Paper

Francesca Margheri, Cristina Luciani, Maria Letizia Taddei, Elisa Giannoni, Anna Laurenzana, Alessio Biagioni, Anastasia ChillÃ, Paola Chiarugi, Gabriella Fibbi, Mario Del Rosso

Published Mar 10, 2014 · Vol. 5, No. 6 · pp. 1538-1553

Keywords: uPAR, mesenchymal movement, amoeboid movement, prostate carcinoma, melanoma

Galectin-3 induces cell migration via a calcium-sensitive MAPK/ERK1/2 pathway Research Paper

Xiaoge Gao, Vitaly Balan, Guihua Tai, Avraham Raz

Published Feb 19, 2014 · Vol. 5, No. 8 · pp. 2077-2084

SENP5 mediates breast cancer invasion via a TGFÎ²RI SUMOylation cascade Research Paper

Rivki Cashman, Helit Cohen, Rotem Ben-Hamo, Alona Zilberberg, Sol Efroni

Published Feb 18, 2014 · Vol. 5, No. 4 · pp. 1071-1082

MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway Research Paper

Audrey Bouillez, Viviane Gnemmi, Kelly Gaudelot, Brigitte HÃ©mon, BÃ©linda Ringot, Nicolas Pottier, FranÃ§ois Glowacki, Caroline Butruille, Christelle Cauffiez, Malika Hamdane, Nicolas Sergeant, Isabelle Van Seuningen, Xavier Leroy, SÃ©bastien Aubert, MichaÃ«l Perrais

Published Feb 2, 2014 · Vol. 5, No. 3 · pp. 754-763

Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells Research Paper

Hee Cheol Kim, Yong Sung Kim, Hyun-Woo Oh, Kwoneel Kim, Sang-Seok Oh, Jong-Tae Kim, Bo Yeon Kim, Seon-Jin Lee, Yong-Kyung Choe, Dong Hyeok Kim, Seok-Hyung Kim, Seoung Wan Chae, Kwang Dong Kim, Hee Gu Lee

Published Jan 18, 2014 · Vol. 5, No. 2 · pp. 519-529

Keywords: CTHRC1, ERK, MMP9, Invasion, Colorectal cancer

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Jakob H. Mikkelsen, Zachary T. Resch, Bhanu Kalra, Gopal Savjani, Ajay Kumar, Cheryl A. Conover, Claus Oxvig

Published Jan 17, 2014 · Vol. 5, No. 4 · pp. 1014-1025

Keywords: insulin-like growth factor receptor, pregnancy-associated plasma protein-A, proteolytic inhibition, therapeutic antibody, xenograft mouse model

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells Research Paper

Tania Fontanil, Susana Rua, Maria Llamazares, Angela Moncada-Pazos, Pedro M. Quiros, Olivia Garcia-Suarez, Jose A. Vega, Takako Sasaki, Yamina Mohamedi, Manuel M. Esteban, Alvaro J. Obaya, Santiago Cal

Published Jan 12, 2014 · Vol. 5, No. 5 · pp. 1253-1264

Keywords: extracellular matrix, metalloprotease, ADAMTS, fibulin, breast cancer

Perspectives of TGF-Î² inhibition in pancreatic and hepatocellular carcinomas Review

Cindy Neuzillet, Armand de Gramont, AnnemilaÃ¯ Tijeras-Raballand, Louis de Mestier, JÃ©rÃ´me Cros, Sandrine Faivre, Eric Raymond

Published Dec 18, 2013 · Vol. 5, No. 1 · pp. 78-94

Keywords: SMAD, stellate cells, extracellular matrix, EMT, TGF-Î² inhibitors

EFEMP1 induces Î³-secretase/Notch-mediated temozolomide resistance in glioblastoma Research Paper

Lotte Hiddingh, Bakhos A. Tannous, Jian Teng, Bas Tops, Judith Jeuken, Esther Hulleman, Sandra H. Boots-Sprenger, W. Peter Vandertop, David P. Noske, Gertjan J.L. Kaspers, Pieter Wesseling, Thomas Wurdinger

Published Dec 7, 2013 · Vol. 5, No. 2 · pp. 363-374

Keywords: Temozolomide resistance, glioblastoma, EFEMP1, Î³-secretase, Notch, GSI

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system Research Paper

Sun-Hye Lee, Tae-Gyun Woo, Su-Jin Lee, Nam-Chul Ha, Bum-Joon Park

Published Dec 2, 2013 · Vol. 4, No. 12 · pp. 2523-2531

Keywords: p53 core domain, Oncogenic K-Ras, Caveolin-1, Drug delivery

A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1 Research Paper

LucÃa Cabal-Hierro, Noelia Artime, JuliÃ¡n Iglesias, Miguel A. Prado, Lorea Ugarte-Gil, Pedro Casado, BelÃ©n FernÃ¡ndez-GarcÃa, Bryant G. Darnay, Pedro S. Lazo

Published Nov 29, 2013 · Vol. 5, No. 1 · pp. 224-236

Keywords: TNF receptors, Death Receptors, TRAF2, Apoptosis, NF-kappaB

Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death Research Paper

Eran Schmukler, Eya Wolfson, Roni Haklai, Galit Elad-Sfadia, Yoel Kloog, Ronit Pinkas-Kramarski

Published Nov 20, 2013 · Vol. 5, No. 1 · pp. 173-184

Keywords: Autophagy, Ras, Transformation, signal transduction.

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles Research Paper

Kerstin Menck, Florian Klemm, Julia Christina Gross, Tobias Pukrop, Dirk Wenzel, Claudia Binder

Published Oct 21, 2013 · Vol. 4, No. 11 · pp. 2057-2066

Keywords: Breast cancer, exosomes, Evi, microvesicles, macrophages, Wnt 5a

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas Research Paper

Julia M. Fraile, Gonzalo R. OrdoÃ±ez, Pedro M. Quiros, Aurora Astudillo, Jose A. Galvan, Dolors Colomer, Carlos Lopez-Otin, Jose M.P. Freije, Xose S. Puente

Published Sep 15, 2013 · Vol. 4, No. 11 · pp. 1919-1932

Keywords: proteolysis, metastasis, invasion, cancer

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

Sandra Cascio, Adam M Farkas, Rebecca P Hughey, Olivera J Finn

Published Sep 7, 2013 · Vol. 4, No. 10 · pp. 1686-1697

Keywords: MUC1, CIN85, protein-protein interaction, cell migration, metastasis, novel targets, glycosylation

Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth Research Paper

Julin Shuxian Wong, Emma Warbrick, Borek Vojtesek, Jeffrey Hill, David Philip Lane

Published Jun 29, 2013 · Vol. 4, No. 7 · pp. 1019-1036

Keywords: c-Met, seeMet 2, monoclonal antibody, temperature sensitive & cryptic epitope

Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5 Research Paper

Huabo Wang, Jay Chauhan, Angela Hu, Kelsey Pendleton, Jeremy L. Yap, Philip E. Sabato, Jace W. Jones, Mariarita Perri, Jianshi Yu, Erika Cione, Maureen A. Kane, Steven Fletcher, Edward V. Prochownik

Published Jun 22, 2013 · Vol. 4, No. 6 · pp. 936-949

Keywords: 10058-F4, 10074-G5, intrinsically disordered proteins, JQ-1, BRD4

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models Research Paper

Diersch Sandra, Patrick Wenzel, Melanie Szameitat, Philipp Eser, Mariel C Paul, Barbara Seidler, Stefan Eser, Marlena Messer, Maximilian Reichert, Philipp Pagel, Irene Esposito, Roland M Schmid, Dieter Saur, GÃ¼nter Schneider

Published Feb 26, 2013 · Vol. 4, No. 2 · pp. 277-288

Keywords: pancreatic cancer, PI3K, Efemp1, p27, Bez235

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Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity Research Paper

17Î²-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells Research Paper

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style Research Paper

Galectin-3 induces cell migration via a calcium-sensitive MAPK/ERK1/2 pathway Research Paper

SENP5 mediates breast cancer invasion via a TGFÎ²RI SUMOylation cascade Research Paper

MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway Research Paper

Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells Research Paper

Perspectives of TGF-Î² inhibition in pancreatic and hepatocellular carcinomas Review

EFEMP1 induces Î³-secretase/Notch-mediated temozolomide resistance in glioblastoma Research Paper

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system Research Paper

A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1 Research Paper

Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death Research Paper

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles Research Paper

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas Research Paper

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth Research Paper

Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5 Research Paper

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity Research Paper

17Î²-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells Research Paper

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style Research Paper

Galectin-3 induces cell migration via a calcium-sensitive MAPK/ERK1/2 pathway Research Paper

SENP5 mediates breast cancer invasion via a TGFÎ²RI SUMOylation cascade Research Paper

MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway Research Paper

Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells Research Paper

Perspectives of TGF-Î² inhibition in pancreatic and hepatocellular carcinomas Review

EFEMP1 induces Î³-secretase/Notch-mediated temozolomide resistance in glioblastoma Research Paper

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system Research Paper

A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1 Research Paper

Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death Research Paper

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles Research Paper

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas Research Paper

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth Research Paper

Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5 Research Paper

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models Research Paper