The Oncosearch | Oncotarget

Down syndrome iPSC model: endothelial perspective on tumor development Research Paper

Mariana Perepitchka, Yekaterina Galat, Igor P. Beletsky, Philip M. Iannaccone, Vasiliy Galat

Published Aug 12, 2020 · Vol. 11, No. 36 · pp. 3387-3404

Keywords: Down syndrome, iPSC-derived endothelial model, T21 genome-wide Implications, meta-analysis, tumor microenvironment

Obinutuzumab (GA101) vs. rituximab significantly enhances cell death, antibody-dependent cytotoxicity and improves overall survival against CD20+ primary mediastinal B-cell lymphoma (PMBL) in a xenograft NOD-scid IL2Rgnull (NSG) mouse model: a potential targeted agent in the treatment of PMBL Research Paper

Yaya Chu, Aradhana Awasthi, Sanghoon Lee, Dina Edani, Changhong Yin, Jessica Hochberg, Tishi Shah, Tae-Hoon Chung, Janet Ayello, Carmella van de Ven, Christian Klein, Dean Lee, Mitchell S. Cairo

Published Jul 21, 2020 · Vol. 11, No. 32 · pp. 3035-3047

Keywords: Obinutuzumab, rituximab, survival, primary mediastinal large B-cell lymphoma, antibody-dependent cellular cytotoxicity

Important players in carcinogenesis as potential targets in cancer therapy: an update Review

Justyna Magdalena Hermanowicz, Iwona Kwiatkowska, Dariusz Pawlak

Published Jul 21, 2020 · Vol. 11, No. 32 · pp. 3078-3101

Keywords: modulators of carcinogenesis, acetylcholine, peroxisome proliferator-activated receptors, aquaporins

Carnosic acid increases sorafenib-induced inhibition of ERK1/2 and STAT3 signaling which contributes to reduced cell proliferation and survival of hepatocellular carcinoma cells Research Paper

Xuening Wang, Priya Gupta, Yasmeen Jramne, Michael Danilenko, Dongfang Liu, George P. Studzinski

Published Jul 16, 2020 · Vol. 11, No. 33 · pp. 3129-3143

Keywords: sorafenib, carnosic acid, ERK1/2, STAT3, hepatoma

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Glenson Samuel, Jennifer Crow, Jon B. Klein, Michael L. Merchant, Emily Nissen, Devin C. Koestler, Kris Laurence, Xiaobo Liang, Kathleen Neville, Vincent Staggs, Atif Ahmed, Safinur Atay, Andrew K. Godwin

Published Jul 7, 2020 · Vol. 11, No. 31 · pp. 2995-3012

Keywords: Ewing sarcoma, EWS-ETS, biomarkers, extracellular vesicles, exosomes

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity Research Paper

Sumit Bhattacharyya, Leo Feferman, Xiaorui Han, Ke Xia, Fuming Zhang, Robert J. Linhardt, Joanne K. Tobacman

Published May 28, 2020 · Vol. 11, No. 24 · pp. 2327-2344

Keywords: sulfotransferase, sulfatase, chondroitin sulfate, Wnt, EMT

Profiling the circulating mRNA transcriptome in human liver disease Research Paper

Aejaz Sayeed, Brielle E. Dalvano, David E. Kaplan, Usha Viswanathan, John Kulp, Alhaji H. Janneh, Lu-Yu Hwang, Adam Ertel, Cataldo Doria, Timothy Block

Published May 23, 2020 · Vol. 11, No. 23 · pp. 2216-2232

Keywords: hepatocellular carcinoma, circulating transcripts, biomarkers, liver cirrhosis, extracellular vesicles

Anticancer effect of physical activity is mediated by modulation of extracellular microRNA in blood Research Paper

Alessandra Pulliero, Ming You, Pradeep Chaluvally-Raghavan, Barbara Marengo, Cinzia Domenicotti, Barbara Banelli, Paolo Degan, Luigi Molfetta, Fabio Gianiorio, Alberto Izzotti

Published May 10, 2020 · Vol. 11, No. 22 · pp. 2106-2119

Keywords: circulating microRNAs, sports and exercise, carcinogenesis, cancer prevention, microRNA transfection

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Katherine M. Bever, Erkut H. Borazanci, Elizabeth A. Thompson, Jennifer N. Durham, Kimberly Pinero, Gayle S. Jameson, Amber Vrana, Meizheng Liu, Cara Wilt, Annie A. Wu, Wei Fu, Hao Wang, Yafu Yin, Jeffrey P. Leal, Ana De Jesus-Acosta, Lei Zheng, Daniel A. Laheru, Daniel D. Von Hoff, Elizabeth M. Jaffee, Jonathan D. Powell, Dung T. Le

Published Apr 23, 2020 · Vol. 11, No. 21 · pp. 1929-1941

Keywords: pancreatic cancer, mTOR inhibition, maintenance therapy, metformin

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

Suparna Mazumder, Valerie Swank, Anton A. Komar, Justin M. Johnson, Vincent K. Tuohy

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1894-1910

Keywords: monoclonal antibody, anti-Müllerian hormone receptor type II, immunotherapy, ovarian cancer, 4D12G1

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Diana Barea Roldán, Matthias Grimmler, Christoph Hartmann, Stefanie Hubich-Rau, Tim Beißert, Claudia Paret, Giuseppe Cagna, Christoph Rohde, Stefan Wöll, Michael Koslowski, Özlem Türeci, Ugur Sahin

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1862-1875

Keywords: PLAC1, tumorigenesis, extracellular matrix, fibroblast growth factor, AKT

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1 Research Paper

Hisham S. Alhajala, John L. Markley, Jin Hae Kim, Mona M. Al-Gizawiy, Kathleen M. Schmainda, John S. Kuo, Christopher R. Chitambar

Published Apr 15, 2020 · Vol. 11, No. 17 · pp. 1531-1544

Keywords: glioblastoma, iron, gallium, metformin, mitochondrial complex I

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Yetirajam Rajesh, Angana Biswas, Payel Banik, Ipsita Pal, Subhayan Das, Sachin A. Borkar, Hardik Sardana, Abhijit Saha, Swadesh K. Das, Luni Emdad, Paul B. Fisher, Mahitosh Mandal

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1097-1108

Keywords: HSPB1, RNAseq, Fli-1, radioresistant GBM, temozolomide resistant GBM

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Betul Gok Yavuz, Roberto Carmagnani Pestana, Yehia I. Abugabal, Sunil Krishnan, Jian Chen, Manal M. Hassan, Robert A. Wolff, Asif Rashid, Hesham M. Amin, Ahmed O. Kaseb

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1186-1201

Keywords: hepatocellular carcinoma, stellate cells, myofibroblasts, liver fibrosis, immunotherapy

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

Eduardo Listik, Leny Toma

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 828-845

Keywords: glioblastoma, glypican-1, tumorigenesis, chemotherapy resistance, temozolomide

Retraction: Neutrophil extracellular traps promote peritoneal metastasis of colon cancer cells Retraction

Amr A. Al-Haidari, Nader Algethami, Mattias Lepsenyi, Milladur Rahman, Ingvar Syk, Henrik Thorlacius

Published Jan 30, 2020 · Vol. 11, No. 6 · pp. 670-670

Correction: A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice Correction

Prakash Gangadaran, Xiu Juan Li, Ho Won Lee, Ji Min Oh, Senthilkumar Kalimuthu, Ramya Lakshmi Rajendran, Seung Hyun Son, Se Hwan Baek, Thoudam Debraj Singh, Liya Zhu, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn

Published Jan 28, 2020 · Vol. 11, No. 11 · pp. 1004-1005

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models Research Paper

Tal Feldman, Iris Grossman-Haham, Yoav Elkis, Patrick Vilela, Neta Moskovits, Iris Barshack, Tomer M. Salame, Deborah Fass, Tal Ilani

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 386-398

Keywords: monoclonal antibody inhibitor, tumor microenvironment, fibroblasts, extracellular matrix remodeling, disulfide bonds

Characterization of unique PMEPA1 gene splice variants (isoforms d and e) from RNA Seq profiling provides novel insights into prognostic evaluation of prostate cancer Research Paper

Shashwat Sharad, Allissa Amanda Dillman, Zsófia M. Sztupinszki, Zoltan Szallasi, Inger Rosner, Jennifer Cullen, Shiv Srivastava, Alagarsamy Srinivasan, Hua Li

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 362-377

Keywords: prostate cancer, PMEPA1, gene isoform, splice variant, TGF-β

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

Klara Fodor, Nikoletta Dobos, Andrew Schally, Zita Steiber, Gabor Olah, Eva Sipos, Lorant Szekvolgyi, Gabor Halmos

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 175-187

Keywords: uveal melanoma, luteinizing hormone-releasing hormone (LHRH) receptor, angiogenesis, MASPIN/SERPINB5, AEZS-108 (AN-152/Zoptarelin Doxorubicin Acetate)

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Down syndrome iPSC model: endothelial perspective on tumor development Research Paper

Important players in carcinogenesis as potential targets in cancer therapy: an update Review

Carnosic acid increases sorafenib-induced inhibition of ERK1/2 and STAT3 signaling which contributes to reduced cell proliferation and survival of hepatocellular carcinoma cells Research Paper

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity Research Paper

Profiling the circulating mRNA transcriptome in human liver disease Research Paper

Anticancer effect of physical activity is mediated by modulation of extracellular microRNA in blood Research Paper

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1 Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

Retraction: Neutrophil extracellular traps promote peritoneal metastasis of colon cancer cells Retraction

Correction: A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice Correction

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models Research Paper

Characterization of unique PMEPA1 gene splice variants (isoforms d and e) from RNA Seq profiling provides novel insights into prognostic evaluation of prostate cancer Research Paper

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Down syndrome iPSC model: endothelial perspective on tumor development Research Paper

Important players in carcinogenesis as potential targets in cancer therapy: an update Review

Carnosic acid increases sorafenib-induced inhibition of ERK1/2 and STAT3 signaling which contributes to reduced cell proliferation and survival of hepatocellular carcinoma cells Research Paper

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity Research Paper

Profiling the circulating mRNA transcriptome in human liver disease Research Paper

Anticancer effect of physical activity is mediated by modulation of extracellular microRNA in blood Research Paper

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1 Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

Retraction: Neutrophil extracellular traps promote peritoneal metastasis of colon cancer cells Retraction

Correction: A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice Correction

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models Research Paper

Characterization of unique PMEPA1 gene splice variants (isoforms d and e) from RNA Seq profiling provides novel insights into prognostic evaluation of prostate cancer Research Paper

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper