The Oncosearch | Oncotarget

Integrated copy number and miRNA expression analysis in triple negative breast cancer of Latin American patients Research Paper

Bruna M. Sugita, Silma R. Pereira, Rodrigo C. de Almeida, Mandeep Gill, Akanksha Mahajan, Anju Duttargi, Saurabh Kirolikar, Paolo Fadda, Rubens S. de Lima, Cicero A. Urban, Kepher Makambi, Subha Madhavan, Simina M. Boca, Yuriy Gusev, Iglenir J. Cavalli, Enilze M.S.F. Ribeiro, Luciane R. Cavalli

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6184-6203

Keywords: microRNA, triple-negative breast cancer, copy number, latinas, disparities

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer Research Paper

C. Andrew Boswell, Daniela Bumbaca Yadav, Eduardo E. Mundo, Shang-Fan Yu, Jennifer Arca Lacap, Aimee Fourie-O’Donohue, Katherine R. Kozak, Gregory Z. Ferl, Crystal Zhang, Jason Ho, Sheila Ulufatu, Leslie A. Khawli, Kedan Lin

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6234-6244

Keywords: antibody-drug conjugate, prostate cancer, pharmacokinetics, TENB2, imaging

The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts Research Paper

Leonid Visochek, Dikla Atias, Itay Spektor, Asher Castiel, Talia Golan, Malka Cohen-Armon

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6269-6282

Keywords: PJ34, pancreas cancer, stroma, PANC1 cancer xenografts

The positivity rate of 68Gallium-PSMA-11 ligand PET/CT depends on the serum PSA-value in patients with biochemical recurrence of prostate cancer Research Paper

Manuela A. Hoffmann, Hans-Georg Buchholz, Helmut J. Wieler, Thomas Höfner, Jonas Müller-Hübenthal, Ludwin Trampert, Mathias Schreckenberger

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6124-6137

Keywords: positivity rate, 68Gallium-PSMA PET/CT, prostate-specific antigen, prostate cancer, biochemical recurrence

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Hwudaurw Chen, Earlphia Sells, Ritu Pandey, Edward R. Abril, Chiu-Hsieh Hsu, Robert S. Krouse, Raymond B. Nagle, Georgios Pampalakis, Georgia Sotiropoulou, Natalia A. Ignatenko

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6062-6078

Keywords: colorectal cancer, kallikrein-related peptidase 6 or KLK6, SMAD2/3, epithelial-mesenchymal transition, HMGA2

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells Research Paper

Channay Naidoo, Cherie Ann Kruger, Heidi Abrahamse

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6079-6095

Keywords: metastatic melanoma, nano active targeting, zinc phthalocyanine tetra-sulphonic acid, photodynamic therapy

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

Abbas Hadji, Greta K. Schmitt, Mathew R. Schnorenberg, Lauren Roach, Connie M. Hickey, Logan B. Leak, Matthew V. Tirrell, James L. LaBelle

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6219-6233

Keywords: MCL-1, BIM, BH3 mimetic, stapled peptides, apoptosis

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Manti Guha, Satish Srinivasan, Maura M. Sheehan, Takashi Kijima, Gordon Ruthel, Kelly Whelan, Koji Tanaka, Andres Klein-Szanto, Prasanna M. Chandramouleeswaran, Hiroshi Nakagawa, Narayan G. Avadhani

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6245-6259

Keywords: mitochondrial DNA, MPV17, ESCC, telomere, 3D organoid

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Jun Gong, Edik M. Blais, Joseph R. Bender, Michelle Guan, Veronica Placencio-Hickok, Emanuel F. Petricoin, Michael J. Pishvaian, Gary Gregory, Richard Tuli, Andrew E. Hendifar

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6260-6268

Keywords: pancreatic neuroendocrine tumors, genomic profiling, proteomic profiling, molecular pathways, co-occurring alterations

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures Research Paper

Inayatullah Shaikh, Afzal Ansari, Garima Ayachit, Monika Gandhi, Priyanka Sharma, Shivarudrappa Bhairappanavar, Chaitanya G. Joshi, Jayashankar Das

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6168-6183

Keywords: tobacco, head and neck squamous cell carcinoma (HNSCC), differentially expressed genes, hub gene, miRNA

The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients Research Paper

Aarash K. Roshandel, Christopher M. Busch, Jennifer Van Mullekom, Joshua A. Cuoco, Cara M. Rogers, Lisa S. Apfel, Eric A. Marvin, Harald W. Sontheimer, Robyn A. Umans

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6204-6218

Keywords: p53, TP53, immunohistochemistry, gene sequencing, glioblastoma multiforme

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

Shiho Fukui, Kazunori Nagasaka, Yuko Miyagawa, Ryoko Kikuchi-Koike, Yoshiko Kawata, Ranka Kanda, Takayuki Ichinose, Takeru Sugihara, Haruko Hiraike, Osamu Wada-Hiraike, Yuko Sasajima, Takuya Ayabe

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5932-5948

Keywords: ovarian cancer, bAP15, TGF-β/Smad signaling, UCHL5, apoptosis

ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer Research Paper

Nikhil Gupta, Jung Eun Park, Wilford Tse, Jee Keem Low, Oi Lian Kon, Neil McCarthy, Siu Kwan Sze

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5970-5982

Keywords: pancreatic cancer, hypoxia tumor, ERO1α, SILAC, proteomics

Splicing regulatory factors in breast cancer hallmarks and disease progression Review

Esmee Koedoot, Liesanne Wolters, Bob van de Water, Sylvia E. Le Dévédec

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 6021-6037

Keywords: hallmarks of cancer, breast cancer, alternative splicing, splice factors, RNA sequencing

Germline mutations in cancer-predisposition genes in patients with biliary tract cancer Research Paper

Takeshi Terashima, Kumiko Umemoto, Hideaki Takahashi, Hiroko Hosoi, Erina Takai, Shunsuke Kondo, Yasunari Sakamoto, Shuichi Mitsunaga, Izumi Ohno, Yusuke Hashimoto, Mitsuhito Sasaki, Masafumi Ikeda, Kazuaki Shimada, Shuichi Kaneko, Shinichi Yachida, Kokichi Sugano, Takuji Okusaka, Chigusa Morizane

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5949-5957

Keywords: germline mutations, biliary tract cancer, hereditary breast cancer syndrome, hereditary ovarian cancer syndrome, cancer-predisposition genes

Malignant ascites: a source of therapeutic protein against ovarian cancer? Research Paper

Pascale Ribaux, Aurore Britan, Gabriele Thumann, Florence Delie, Patrick Petignat, Marie Cohen

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5894-5905

Keywords: ascites, PEDF, sleeping beauty transposon, ovarian cancer, tumor development

Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer Research Paper

Yosuke Ooizumi, Hiroshi Katoh, Mitsuo Yokota, Masahiko Watanabe, Keishi Yamashita

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5906-5918

Keywords: HOPX, papillary thyroid cancer, epigenetic silencing, promoter methylation

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Prachi Namjoshi, Lori Showalter, Brian J. Czerniecki, Gary K. Koski

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 6006-6020

Keywords: apoptosis, HER-2, T-helper 1, IFN-γ, TNF-α

DPA shows comparable chemotherapy sensitizing effects as EPA upon cellular incorporation in tumor cells Research Paper

Francina J. Dijk, Miriam van Dijk, Bram Dorresteijn, Klaske van Norren

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5983-5992

Keywords: DPA, fish oil, nutrition, chemotherapy, cancer

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Qiang Qiu, Mengyuan Li, Linyu Yang, Minghai Tang, Li Zheng, Fang Wang, Huandi Qiu, Cailing Liang, Ning Li, Dongni Yi, Yuyao Yi, Cong Pan, Shengyong Yang, Lijuan Chen, Yiguo Hu

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5993-6005

Keywords: glutaminase1, multiple myeloma, BPTES, cMYC/KRAS12V-transduced plasmacytoma, mouse model

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Integrated copy number and miRNA expression analysis in triple negative breast cancer of Latin American patients Research Paper

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer Research Paper

The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts Research Paper

The positivity rate of 68Gallium-PSMA-11 ligand PET/CT depends on the serum PSA-value in patients with biochemical recurrence of prostate cancer Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells Research Paper

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures Research Paper

The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients Research Paper

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer Research Paper

Splicing regulatory factors in breast cancer hallmarks and disease progression Review

Germline mutations in cancer-predisposition genes in patients with biliary tract cancer Research Paper

Malignant ascites: a source of therapeutic protein against ovarian cancer? Research Paper

Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

DPA shows comparable chemotherapy sensitizing effects as EPA upon cellular incorporation in tumor cells Research Paper

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Integrated copy number and miRNA expression analysis in triple negative breast cancer of Latin American patients Research Paper

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer Research Paper

The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts Research Paper

The positivity rate of 68Gallium-PSMA-11 ligand PET/CT depends on the serum PSA-value in patients with biochemical recurrence of prostate cancer Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells Research Paper

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures Research Paper

The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients Research Paper

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer Research Paper

Splicing regulatory factors in breast cancer hallmarks and disease progression Review

Germline mutations in cancer-predisposition genes in patients with biliary tract cancer Research Paper

Malignant ascites: a source of therapeutic protein against ovarian cancer? Research Paper

Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

DPA shows comparable chemotherapy sensitizing effects as EPA upon cellular incorporation in tumor cells Research Paper

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper