The Oncosearch | Oncotarget

Correction: Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer Correction

Shu-Heng Jiang, Yang Wang, Jian-Yu Yang, Jun Li, Ming-Xuan Feng, Ya-Hui Wang, Xiao-Mei Yang, Ping He, Guang-Ang Tian, Xiao-Xin Zhang, Qing Li, Xiao-Yan Cao, Yan-Miao Huo, Min-Wei Yang, Xue-Liang Fu, Jiao Li, De-Jun Liu, Miao Dai, Shan-Yun Wen, Jian-Ren Gu, Jie Hong, Rong Hua, Zhi-Gang Zhang, Yong-Wei Sun

Published Oct 12, 2021

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

Christina Schmitt, Anna-Alice Schulz, Ria Winkelmann, Kevin Smith, Peter J. Wild, Melanie Demes

Published Oct 5, 2021 · Vol. 12, No. 22 · pp. 2273-2282

Keywords: next-generation sequencing (NGS), non-small cell lung cancer (NSCLC), fluorescence in situ hybridization (FISH), MET amplification, routine diagnostics

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda

Published Sep 28, 2021 · Vol. 12, No. 21 · pp. 2114-2130

Keywords: TMZ, MMR, ATR, HR, REV3L

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Monica Sharma, Isabel Castro-Piedras, Fahmida Rasha, Sabarish Ramachandran, Souad R. Sennoune, Kathryn Furr, Sharilyn Almodovar, Vadivel Ganapathy, Matthew B. Grisham, Rakhshanda Layeequr Rahman, Kevin Pruitt

Published Sep 28, 2021 · Vol. 12, No. 22 · pp. 2234-2251

Keywords: dishevelled (DVL), post-translational modification, lysine residue, gene expression, chromatin immunoprecipitation (ChIP)

Cell fusion as a link between the SARS-CoV-2 spike protein, COVID-19 complications, and vaccine side effects Research Perspective

Yuri Lazebnik

Published Sep 27, 2021 · Vol. 12, No. 25 · pp. 2476-2488

Keywords: cell fusion, thrombosis, neuropathy, cancer, vaccines

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Ilyas Sahin, Andrew George, Shengliang Zhang, Kelsey E. Huntington, Zehra Ordulu, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 24, 2021 · Vol. 12, No. 21 · pp. 2131-2146

Keywords: cancer immunotherapy, immune checkpoint inhibitors, hyperprogressive disease (HPD), hyperprogression (HP), humanized mouse

Correction: AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling Correction

Jia Li, Yuanwei Guo, Lili Duan, Xinglin Hu, Xi Zhang, Jian Hu, Li Huang, Rongzhang He, Zheng Hu, Weihao Luo, Tan Tan, Renbin Huang, Duanfang Liao, Yuan-Shan Zhu, Di-Xian Luo

Published Sep 22, 2021

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis Research Paper

Jessica I. Christian, Agnieszka Pastula, Andreas Herbst, Jens Neumann, Maximilian K. Marschall, Andrea Ofner, Heike Zierahn, Marlon R. Schneider, Eckhard Wolf, Michael Quante, Frank T. Kolligs

Published Sep 22, 2021 · Vol. 13, No. 1 · pp. 615-627

Keywords: DRO1, CCDC80, colorectal cancer, tumor microenvironment, tumor suppressor

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Issam Makhoul, Saddam Mohammed Ibrahim, Muhammad Abu-Rmaileh, Fariba Jousheghany, Eric R. Siegel, Lora J. Rogers, John J. Lee, Sergio Pina-Oviedo, Ginell R. Post, J. Thaddeus Beck, Thomas Kieber-Emmons, Behjatolah Monzavi-Karbassi

Published Sep 16, 2021 · Vol. 12, No. 22 · pp. 2252-2265

Keywords: cancer vaccine, peptide mimotopes, combination therapy, breast cancer

Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients Research Paper

Sofia Leaf, Lindsey Carlsen, Wafik S. El-Deiry

Published Sep 15, 2021 · Vol. 12, No. 20 · pp. 1992-2005

Keywords: breast cancer, colorectal cancer, BRCA1, biomarker, early onset

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Shuai Zhao, Wafik S. El-Deiry

Published Sep 15, 2021 · Vol. 12, No. 20 · pp. 1970-1979

Keywords: Smurf2, CDK4/6 inhibition, HIF1alpha, hypoxia, cancer therapy

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma Review

Hung Q. Doan, Leon Chen, Zeena Nawas, Heng-Huan Lee, Sirunya Silapunt, Michael Migden

Published Sep 13, 2021 · Vol. 12, No. 20 · pp. 2089-2100

Keywords: basal cell carcinoma, Hedgehog pathway inhibitor, resistance, switching, combination therapy

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Kelsey E. Huntington, Anna Louie, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 11, 2021 · Vol. 12, No. 20 · pp. 1980-1991

Keywords: cytokine profiling, inflammatory response, chemokine, growth factor, immune profiling

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Edmond J. Feris, John W. Hinds, Michael D. Cole

Published Sep 11, 2021 · Vol. 12, No. 21 · pp. 2147-2157

Keywords: cancer, drug discovery, targeted therapy, oncogene, transcription factor

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Arvin Medhat, Alla Arzumanyan, Mark A. Feitelson

Published Sep 11, 2021 · Vol. 12, No. 24 · pp. 2421-2433

Keywords: chronic liver disease, hepatocellular carcinoma, HBx, functional cure, epigenetic

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey Research Paper

Subotheni Thavaneswaran, Mandy Ballinger, Phyllis Butow, Bettina Meiser, David Goldstein, Frank Lin, Christine Napier, David Thomas, Megan Best

Published Sep 9, 2021 · Vol. 12, No. 21 · pp. 2169-2176

Keywords: comprehensive genomic profiling, precision medicine, targeted treatment selection using genomics, communication, clinicians' experiences with utilising genomic findings in a pan-cancer setting to inform treatment selection

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Lindsey Carlsen, Christoph Schorl, Kelsey Huntington, Liz Hernandez-Borrero, Aakash Jhaveri, Shengliang Zhang, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 8, 2021 · Vol. 12, No. 20 · pp. 2006-2021

Keywords: chemotherapy mechanism, colon cancer, 5-fluorouracil, irinotecan, oxaliplatin

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

Nicholas Cho, Sooah Ko, Monica Shokeen

Published Sep 7, 2021 · Vol. 12, No. 20 · pp. 2039-2050

Keywords: near-infrared (NIR) fluorescence, multiple myeloma (MM), cluster of differentiation 38 (CD38), antibody-drug conjugate (ADC), small animal optical imaging

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Erling Håland, Ingrid Nyhus Moen, Elias Veidal, Hanne Hella, Kristine Misund, Tobias S. Slørdahl, Kristian K. Starheim

Published Sep 4, 2021 · Vol. 12, No. 21 · pp. 2158-2168

Keywords: multiple myeloma, TAK1, apoptosis, NF-κB, cancer treatment

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Jan A. Kaczmarczyk, Rhonda R. Roberts, Brian T. Luke, King C. Chan, Carly M. Van Wagoner, Robin A. Felder, Richard G. Saul, Colantonio Simona, Josip Blonder

Published Sep 3, 2021 · Vol. 12, No. 20 · pp. 2022-2038

Keywords: lung cancer, proteomics, 2D vs. 3D cultured cells, preclinical testing model, drug target discovery

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Correction: Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer Correction

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Cell fusion as a link between the SARS-CoV-2 spike protein, COVID-19 complications, and vaccine side effects Research Perspective

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Correction: AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling Correction

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis Research Paper

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma Review

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey Research Paper

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Correction: Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer Correction

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide Priority Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Cell fusion as a link between the SARS-CoV-2 spike protein, COVID-19 complications, and vaccine side effects Research Perspective

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Correction: AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling Correction

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis Research Paper

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma Review

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey Research Paper

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper