The Oncosearch | Oncotarget

HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs) Research Paper

Sonia Paget, Marion Dubuissez, Vanessa Dehennaut, Joe Nassour, Brennan T. Harmon, Nathalie Spruyt, Ingrid Loison, Corinne Abbadie, Brian R. Rood, Dominique Leprince

Published Dec 7, 2016 · Vol. 8, No. 2 · pp. 2916-2935

T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice Research Paper

Wen Liu, Wenjie Guo, Lihong Shen, Zhen Chen, Qiong Luo, Xiaolin Luo, GenSheng Feng, Yongqian Shu, Yanhong Gu, Qiang Xu, Yang Sun

Published Dec 7, 2016 · Vol. 8, No. 5 · pp. 7586-7597

The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus Research Paper

Ramiro VÃ¡zquez, MarÃa E. Riveiro, Lucile Astorgues-Xerri, Elodie Odore, Keyvan Rezai, Eugenio Erba, NicolÃ² Panini, Andrea Rinaldi, Ivo Kwee, Luca Beltrame, Mohamed Bekradda, Esteban Cvitkovic, Francesco Bertoni, Roberta Frapolli, Maurizio D'Incalci

Published Dec 7, 2016 · Vol. 8, No. 5 · pp. 7598-7613

Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents Research Paper

Donghai Xiong, Jing Pan, Qi Zhang, Eva Szabo, Mark Steven Miller, Ronald A. Lubet, Ming You, Yian Wang

Published Dec 7, 2016 · Vol. 8, No. 12 · pp. 18885-18900

Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions Research Paper

Feng-Che Kuan, Shih-Hong Li, Chih-Liang Wang, Meng-Hung Lin, Ying-Huang Tsai, Cheng-Ta Yang

Published Dec 7, 2016 · Vol. 8, No. 1 · pp. 1343-1353

The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer Research Paper

Yan Dai, Shiguang Jin, Xueping Li, Daxin Wang

Published Dec 7, 2016 · Vol. 8, No. 1 · pp. 1354-1368

Paradoxical induction of growth arrest and apoptosis by EGF via the up-regulation of PTEN by activating Redox factor-1/Egr-1 in human lung cancer cells Research Paper

Je-won Ryu, Sung Sik Choe, Seung-Hee Ryu, Eun-Young Park, Byoung Wook Lee, Tae Keun Kim, Chang Hoon Ha, Sang-wook Lee

Published Dec 7, 2016 · Vol. 8, No. 3 · pp. 4181-4195

Targeting of interleukin (IL)-17A inhibits PDL1 expression in tumor cells and induces anticancer immunity in an estrogen receptor-negative murine model of breast cancer Research Paper

Yun-Feng Ma, Chen Chen, Dongqing Li, Min Liu, Zhuang-Wei Lv, Yanhong Ji, Jiru Xu

Published Dec 7, 2016 · Vol. 8, No. 5 · pp. 7614-7624

MicroRNA-203 predicts human survival after resection of colorectal liver metastasis Research Paper

T. Peter Kingham, Hoang C.B. Nguyen, Jian Zheng, Ioannis T. Konstantinidis, Eran Sadot, Jinru Shia, Deborah Kuk, Steven Zhang, Leonard Saltz, Michael I. Dâ€™Angelica, William R. Jarnagin, Hani Goodarzi, Sohail F. Tavazoie

Published Dec 7, 2016 · Vol. 8, No. 12 · pp. 18821-18831

Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine Research Paper

Costantine Albany, Mary P. Hever-Jardine, Katherine M. von Herrmann, Christina Y. Yim, Janice Tam, Joshua M. Warzecha, Leah Shin, Sarah E. Bock, Brian S. Curran, Aneeq S. Chaudhry, Fred Kim, George E. Sandusky, Pietro Taverna, Sarah J. Freemantle, Brock C. Christensen, Lawrence H. Einhorn, Michael J. Spinella

Published Dec 7, 2016 · Vol. 8, No. 2 · pp. 2949-2959

DPP4/CD26 overexpression in urothelial carcinoma confers an independent prognostic impact and correlates with intrinsic biological aggressiveness Research Paper

Peir-In Liang, Bi-Wen Yeh, Wei-Ming Li, Ti-Chun Chan, I-Wei Chang, Chun-Nung Huang, Ching-Chia Li, Hung-Lung Ke, Hsin-Chih Yeh, Wen-Jeng Wu, Chien-Feng Li

Published Dec 7, 2016 · Vol. 8, No. 2 · pp. 2995-3008

Clinical relevance of cell-free DNA in gastrointestinal tract malignancy Research Paper

Yuan-Tzu Lan, Ming-Huang Chen, Wen-Liang Fang, Chih-Cheng Hsieh, Chien-Hsing Lin, Fang-Yu Jhang, Shung-Haur Yang, Jen-Kou Lin, Wei-Shone Chen, Jeng-Kai Jiang, Pei-Ching Lin, Shih-Ching Chang

Published Dec 7, 2016 · Vol. 8, No. 2 · pp. 3009-3017

Decreased expression of protocadherin 20 is associated with poor prognosis in hepatocellular carcinoma Research Paper

Yanqin Wu, Shuhui Zheng, Jiayan Yao, Minrui Li, Guang Yang, Ning Zhang, Shenghong Zhang, Bihui Zhong

Published Dec 7, 2016 · Vol. 8, No. 2 · pp. 3018-3028

An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in non-small cell lung cancer patients with tumors showing high EGFR gene copy number Clinical Research Papers

Ewa Szutowicz-ZieliÅ„ska, Krzysztof Konopa, Anna Kowalczyk, MaÅ‚gorzata Suszko-KaÅ¼arnowicz, Renata Duchnowska, Aleksandra SzczÄ™sna, Magdalena Ratajska, Aleksander Sowa, Janusz Limon, Wojciech Biernat, Tomasz Burzykowski, Jacek Jassem, RafaÅ‚ Dziadziuszko

Published Dec 4, 2016 · Vol. 8, No. 10 · pp. 17270-17278

Î”Np63Î± and microRNAs: leveraging the epithelial-mesenchymal transition Research Paper

Andrew J. Stacy, Michael P. Craig, Suraj Sakaram, Madhavi Kadakia

Published Dec 4, 2016 · Vol. 8, No. 2 · pp. 2114-2129

Toward the use of precision medicine for the treatment of head and neck squamous cell carcinoma Research Paper

Wang Gong, Yandi Xiao, Zihao Wei, Yao Yuan, Min Qiu, Chongkui Sun, Xin Zeng, Xinhua Liang, Mingye Feng, Qianming Chen Chen

Published Dec 4, 2016 · Vol. 8, No. 2 · pp. 2141-2152

FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway Research Paper

Kun Li, Qunfeng Guo, Jun Yang, Hui Chen, Kewen Hu, Juan Zhao, Xiufeng Pang, Sufang Zhou, Yongyan Dang, Lei Li

Published Dec 3, 2016 · Vol. 8, No. 3 · pp. 5048-5056

Abdominal radical trachelectomy guided by sentinel lymph node biopsy for stage IB1 cervical cancer with tumors >2 cm Research Paper

Xiangyun Deng, Ying Zhang, Dapeng Li, Xiaoling Zhang, Hui Guo, Fei Wang, Xiugui Sheng

Published Dec 3, 2016 · Vol. 8, No. 2 · pp. 3422-3429

The association between clinical prognostic factors and epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) efficacy in advanced non-small-cell lung cancer patients: a retrospective assessment of 94 cases with EGFR mutations Research Paper

Jing-Hui Lin, Dong Lin, Ling Xu, Qiang Wang, Hui-Hua Hu, Hai-Peng Xu, Zhi-Yong He

Published Dec 3, 2016 · Vol. 8, No. 2 · pp. 3412-3421

Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase Research Paper

Luana Lugini, Ilaria Sciamanna, Cristina Federici, Elisabetta Iessi, Enrico Pierluigi Spugnini, Stefano Fais

Published Dec 3, 2016 · Vol. 8, No. 3 · pp. 4147-4155

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HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs) Research Paper

T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice Research Paper

The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus Research Paper

Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents Research Paper

Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions Research Paper

The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer Research Paper

Paradoxical induction of growth arrest and apoptosis by EGF via the up-regulation of PTEN by activating Redox factor-1/Egr-1 in human lung cancer cells Research Paper

Targeting of interleukin (IL)-17A inhibits PDL1 expression in tumor cells and induces anticancer immunity in an estrogen receptor-negative murine model of breast cancer Research Paper

MicroRNA-203 predicts human survival after resection of colorectal liver metastasis Research Paper

Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine Research Paper

DPP4/CD26 overexpression in urothelial carcinoma confers an independent prognostic impact and correlates with intrinsic biological aggressiveness Research Paper

Clinical relevance of cell-free DNA in gastrointestinal tract malignancy Research Paper

Decreased expression of protocadherin 20 is associated with poor prognosis in hepatocellular carcinoma Research Paper

An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in non-small cell lung cancer patients with tumors showing high EGFR gene copy number Clinical Research Papers

Î”Np63Î± and microRNAs: leveraging the epithelial-mesenchymal transition Research Paper

Toward the use of precision medicine for the treatment of head and neck squamous cell carcinoma Research Paper

FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway Research Paper

Abdominal radical trachelectomy guided by sentinel lymph node biopsy for stage IB1 cervical cancer with tumors >2 cm Research Paper

The association between clinical prognostic factors and epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) efficacy in advanced non-small-cell lung cancer patients: a retrospective assessment of 94 cases with EGFR mutations Research Paper

Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs) Research Paper

T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice Research Paper

The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus Research Paper

Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents Research Paper

Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions Research Paper

The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer Research Paper

Paradoxical induction of growth arrest and apoptosis by EGF via the up-regulation of PTEN by activating Redox factor-1/Egr-1 in human lung cancer cells Research Paper

Targeting of interleukin (IL)-17A inhibits PDL1 expression in tumor cells and induces anticancer immunity in an estrogen receptor-negative murine model of breast cancer Research Paper

MicroRNA-203 predicts human survival after resection of colorectal liver metastasis Research Paper

Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine Research Paper

DPP4/CD26 overexpression in urothelial carcinoma confers an independent prognostic impact and correlates with intrinsic biological aggressiveness Research Paper

Clinical relevance of cell-free DNA in gastrointestinal tract malignancy Research Paper

Decreased expression of protocadherin 20 is associated with poor prognosis in hepatocellular carcinoma Research Paper

An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in non-small cell lung cancer patients with tumors showing high EGFR gene copy number Clinical Research Papers

Î”Np63Î± and microRNAs: leveraging the epithelial-mesenchymal transition Research Paper

Toward the use of precision medicine for the treatment of head and neck squamous cell carcinoma Research Paper

FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway Research Paper

Abdominal radical trachelectomy guided by sentinel lymph node biopsy for stage IB1 cervical cancer with tumors >2 cm Research Paper

The association between clinical prognostic factors and epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) efficacy in advanced non-small-cell lung cancer patients: a retrospective assessment of 94 cases with EGFR mutations Research Paper

Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase Research Paper