The Oncosearch | Oncotarget

Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients Research Paper

Mara W. Rosenberg, Kevin Watanabe-Smith, Jeffrey W. Tyner, Cristina E. Tognon, Brian J. Druker, Uma Borate

Published Jun 17, 2020 · Vol. 11, No. 29 · pp. 2807-2818

Keywords: acute myeloid leukemia, drug sensitivity, midostaurin, drug resistance, FLT3

Methylation of a newly identified region of the INS-IGF2 gene determines IGF2 expression in breast cancer tumors and in breast cancer cells Research Paper

Vinodh Kumar Radhakrishnan, Kameswaran Ravichandran, Chibuzo Eke, Amanda Ortiz-Vicil, Qianwei Tan, Marino De León, Daisy D. De León

Published Jun 13, 2020 · Vol. 11, No. 44 · pp. 3904-3920

Keywords: IGF2, INS-IGF2, hypermethylation, DMR, epigenetics

Renal cell tumors convert natural killer cells to a proangiogenic phenotype Research Paper

Yue Guan, Christopher B. Chambers, Taylor Tabatabai, Ha Hatley, Kristin R. Delfino, Kathy Robinson, Shaheen R. Alanee, Sophia Ran, Donald S. Torry, Andrew Wilber

Published Jun 12, 2020 · Vol. 11, No. 26 · pp. 2571-2585

Keywords: kidney cancer, innate immunity, natural killer cells, immunosuppression, angiogenesis

Comparison of the prognostic value of immunoinflammation-based biomarkers in patients with gastric cancer Research Paper

Noriyuki Hirahara, Takeshi Matsubara, Yusuke Fujii, Shunsuke Kaji, Yasunari Kawabata, Ryoji Hyakudomi, Tetsu Yamamoto, Takahito Taniura, Yoshitsugu Tajima

Published Jun 12, 2020 · Vol. 11, No. 27 · pp. 2625-2635

Keywords: gastric cancer, systemic immune-inflammation index, CRP, overall survival

Influence of major BCR-ABL1 transcript subtype on outcome in patients with chronic myeloid leukemia in chronic phase treated frontline with nilotinib Research Paper

Alexis Genthon, Franck Emmanuel Nicolini, Françoise Huguet, Carole Colin-Gil, Marc Berger, Sandrine Saugues, Alexandre Janel, Sandrine Hayette, Pascale Cohny-Makhoul, Nadine Cadoux, Jean-Michel Cayuela, Lydia Campos, Denis Guyotat, Pascale Flandrin-Gresta

Published Jun 12, 2020 · Vol. 11, No. 26 · pp. 2560-2570

Keywords: CML, nilotinib, e13a2, e14a2, BCR-ABL1

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT Research Paper

Wen Jia, Shubham Tripathi, Priyanka Chakraborty, Adithya Chedere, Annapoorni Rangarajan, Herbert Levine, Mohit Kumar Jolly

Published Jun 11, 2020 · Vol. 11, No. 27 · pp. 2611-2624

Keywords: epithelial-mesenchymal transition, mesenchymal-epithelial transition, GRHL2, epigenetics, asymmetric cell division

IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells Research Paper

Rehanna Mansor, Jeff Holly, Rachel Barker, Kalina Biernacka, Hanna Zielinska, Anthony Koupparis, Edward Rowe, Jon Oxley, Alex Sewell, Richard M. Martin, Athene Lane, Lucy Hackshaw-McGeagh, Claire Perks

Published Jun 11, 2020 · Vol. 11, No. 26 · pp. 2543-2559

Keywords: hyperglycaemia, prostate cancer, FOXA1, IGFBP-2, EMT

Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry Research Paper

Janos Schmidt, Béla Kajtár, Kata Juhász, Mária Péter, Tamás Járai, András Burián, László Kereskai, Imre Gerlinger, Tamás Tornóczki, Gábor Balogh, László Vígh, Lászó Márk, Zsolt Balogi

Published Jun 11, 2020 · Vol. 11, No. 28 · pp. 2702-2717

Keywords: Imaging mass spectrometry, tumor marker, lipid tumor marker, S100A8, S100A9

Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation Research Paper

Ron C. Gaba, Lobna Elkhadragy, F. Edward Boas, Sulalita Chaki, Hanna H. Chen, Mohammed El-Kebir, Kelly D. Garcia, Eileena F. Giurini, Grace Guzman, Francesca V. LoBianco, Mario F. Neto, Jordan L. Newson, Aisha Qazi, Maureen Regan, Lauretta A. Rund, Regina M. Schwind, Matthew C. Stewart, Faith M. Thomas, Herbert E. Whiteley, Jiaqi Wu, Lawrence B. Schook, Kyle M. Schachtschneider

Published Jun 10, 2020 · Vol. 11, No. 28 · pp. 2686-2701

Keywords: liver cancer, transgenic pigs, large animal model, interventional radiology, personalized medicine

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter Research Paper

Rive Sarfstein, Haim Werner

Published Jun 9, 2020 · Vol. 11, No. 25 · pp. 2424-2437

Keywords: insulin, insulin-like growth factor-1 (IGF1), insulin receptor, IGF1 receptor, p53

Postoperative atrial fibrillation does not impact on overall survival after esophagectomy in patients with thoracic esophageal cancer: results from a randomized, double-blind, placebo-controlled trial Research Paper

Toshiyasu Ojima, Masaki Nakamura, Keiji Hayata, Junya Kitadani, Masahiro Katsuda, Mikihito Nakamori, Akihiro Takeuchi, Shimpei Maruoka, Naoki Fukuda, Shinta Tominaga, Hideki Motobayashi, Hiroki Yamaue

Published Jun 9, 2020 · Vol. 11, No. 25 · pp. 2414-2423

Keywords: esophageal cancer, atrial fibrillation, landiolol, randomized controlled trial, complication

Mutation profile of primary subungual melanomas in Caucasians Research Paper

Aneta Borkowska, Anna Szumera-Ciećkiewicz, Mateusz Spałek, Paweł Teterycz, Anna Czarnecka, Artur Kowalik, Piotr Rutkowski

Published Jun 8, 2020 · Vol. 11, No. 25 · pp. 2404-2413

Keywords: melanoma, acral melanoma, subungual melanoma, nail apparatus melanoma, SMAD4

Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib: Real-world evidence and in vitro assessment via protein phosphorylation array Research Paper

Tetsu Tomonari, Yasushi Sato, Hironori Tanaka, Takahiro Tanaka, Yasuteru Fujino, Yasuhiro Mitsui, Akihiro Hirao, Tatsuya Taniguchi, Koichi Okamoto, Masahiro Sogabe, Hiroshi Miyamoto, Naoki Muguruma, Harumi Kagiwada, Masashi Kitazawa, Kazuhiko Fukui, Katsuhisa Horimoto, Tetsuji Takayama

Published Jun 8, 2020 · Vol. 11, No. 26 · pp. 2531-2542

Keywords: hepatocellular carcinoma, lenvatinib, sorafenib, hepatic reserve function, FGFR

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Joshua T. Rose, Eliana Moskovitz, Joseph R. Boyd, Jonathan A. Gordon, Nicole A. Bouffard, Andrew J. Fritz, Anuradha Illendula, John H. Bushweller, Jane B. Lian, Janet L. Stein, Sayyed K. Zaidi, Gary S. Stein

Published May 30, 2020 · Vol. 11, No. 26 · pp. 2512-2530

Keywords: mammary epithelial phenotype, epithelial phenotype, RUNX1, CBFβ, mitotic gene bookmarking

Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity Research Paper

Chia-Lung Yang, André Serra-Roma, Marco Gualandi, Nicole Bodmer, Felix Niggli, Johannes Hubertus Schulte, Peter Karl Bode, Olga Shakhova

Published May 30, 2020 · Vol. 11, No. 24 · pp. 2357-2371

Keywords: neuroblastoma, neural crest stem cells, sox geness

Preoperative geriatric nutritional risk index is a useful prognostic indicator in elderly patients with gastric cancer Research Paper

Noriyuki Hirahara, Takeshi Matsubara, Yusuke Fujii, Shunsuke Kaji, Ryoji Hyakudomi, Tetsu Yamamoto, Yuki Uchida, Yoshiko Miyazaki, Kazunari Ishitobi, Yasunari Kawabata, Yoshitsugu Tajima

Published May 30, 2020 · Vol. 11, No. 24 · pp. 2345-2356

Keywords: geriatric nutritional risk index, overall survival, cancer-specific survival, gastric cancer, elderly patients

Preliminary safety and imaging efficacy of the near-infrared fluorescent contrast agent DA364 during fluorescence-guided surgery in dogs with spontaneous superficial tumors Research Paper

Sophie Favril, Chiara Brioschi, Katrien Vanderperren, Eline Abma, Emmelie Stock, Nausikaa Devriendt, Ingeborgh Polis, Hilde De Cock, Alessia Cordaro, Luigi Miragoli, Paolo Oliva, Giovanni Valbusa, Charline Alleaume, Isabelle Tardy, Alessandro Maiocchi, Fabio Tedoldi, Francesco Blasi, Hilde de Rooster

Published May 28, 2020 · Vol. 11, No. 24 · pp. 2310-2326

Keywords: fluorescence-guided surgery, fluorescent contrast agent, near-infrared fluorescence imaging, spontaneous tumors, canine

Validated limited gene predictor for cervical cancer lymph node metastases Research Paper

Joshua D. Bloomstein, Rie von Eyben, Andy Chan, Erinn B. Rankin, Daniel R. Fregoso, Jing Wang-Chiang, Lisa Lee, Liang-Xi Xie, Shannon MacLaughlan David, Henning Stehr, Mohammad S. Esfahani, Amato J. Giaccia, Elizabeth A. Kidd

Published May 27, 2020 · Vol. 11, No. 24 · pp. 2302-2309

Keywords: cervical cancer, metastasis

Exploring the role of survivin in neuroendocrine neoplasms Research Paper

Ahmad Hanif, Sunyoung Lee, Medhavi Gupta, Ankush Chander, Eric D. Kannisto, Achamaporn Punnanitinont, Robert Fenstermaker, Michael Ciesielski, Kristopher Attwood, Jingxin Qiu, Sai Yendamuri, Renuka Iyer

Published May 26, 2020 · Vol. 11, No. 23 · pp. 2246-2258

Keywords: neuroendocrine tumors, survivin, immunohistochemistry, biomarkers, radiosensitivity

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Hee-Don Chae, Ritika Dutta, Bruce Tiu, Fieke W. Hoff, Benedetta Accordi, Valentina Serafin, Minyoung Youn, Min Huang, Nathan Sumarsono, Kara L. Davis, Norman J. Lacayo, Martina Pigazzi, Terzah M. Horton, Steven M. Kornblau, Kathleen M. Sakamoto

Published May 26, 2020 · Vol. 11, No. 25 · pp. 2387-2403

Keywords: acute myeloid leukemia, BI-D1870, RSK, vincristine, spindle assembly checkpoint

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Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients Research Paper

Methylation of a newly identified region of the INS-IGF2 gene determines IGF2 expression in breast cancer tumors and in breast cancer cells Research Paper

Renal cell tumors convert natural killer cells to a proangiogenic phenotype Research Paper

Comparison of the prognostic value of immunoinflammation-based biomarkers in patients with gastric cancer Research Paper

Influence of major BCR-ABL1 transcript subtype on outcome in patients with chronic myeloid leukemia in chronic phase treated frontline with nilotinib Research Paper

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT Research Paper

IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells Research Paper

Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry Research Paper

Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation Research Paper

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter Research Paper

Postoperative atrial fibrillation does not impact on overall survival after esophagectomy in patients with thoracic esophageal cancer: results from a randomized, double-blind, placebo-controlled trial Research Paper

Mutation profile of primary subungual melanomas in Caucasians Research Paper

Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib: Real-world evidence and in vitro assessment via protein phosphorylation array Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity Research Paper

Preoperative geriatric nutritional risk index is a useful prognostic indicator in elderly patients with gastric cancer Research Paper

Preliminary safety and imaging efficacy of the near-infrared fluorescent contrast agent DA364 during fluorescence-guided surgery in dogs with spontaneous superficial tumors Research Paper

Validated limited gene predictor for cervical cancer lymph node metastases Research Paper

Exploring the role of survivin in neuroendocrine neoplasms Research Paper

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients Research Paper

Methylation of a newly identified region of the INS-IGF2 gene determines IGF2 expression in breast cancer tumors and in breast cancer cells Research Paper

Renal cell tumors convert natural killer cells to a proangiogenic phenotype Research Paper

Comparison of the prognostic value of immunoinflammation-based biomarkers in patients with gastric cancer Research Paper

Influence of major BCR-ABL1 transcript subtype on outcome in patients with chronic myeloid leukemia in chronic phase treated frontline with nilotinib Research Paper

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT Research Paper

IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells Research Paper

Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry Research Paper

Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation Research Paper

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter Research Paper

Postoperative atrial fibrillation does not impact on overall survival after esophagectomy in patients with thoracic esophageal cancer: results from a randomized, double-blind, placebo-controlled trial Research Paper

Mutation profile of primary subungual melanomas in Caucasians Research Paper

Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib: Real-world evidence and in vitro assessment via protein phosphorylation array Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity Research Paper

Preoperative geriatric nutritional risk index is a useful prognostic indicator in elderly patients with gastric cancer Research Paper

Preliminary safety and imaging efficacy of the near-infrared fluorescent contrast agent DA364 during fluorescence-guided surgery in dogs with spontaneous superficial tumors Research Paper

Validated limited gene predictor for cervical cancer lymph node metastases Research Paper

Exploring the role of survivin in neuroendocrine neoplasms Research Paper

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper