The Oncosearch | Oncotarget

Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation Priority Research Paper

Jiang-Jiang Qin, Wei Wang, Sukesh Voruganti, Hui Wang, Wei-Dong Zhang, Ruiwen Zhang

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 2623-2640

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Evgeny A. Moskalev, Pouria Jandaghi, Mahdi Fallah, Mehdi Manoochehri, Sandeep K. Botla, Oleg V. Kolychev, Evgeny A. Nikitin, Vladymyr V. Bubnov, M. von Knebel Doeberitz, Oliver Strobel, Thilo Hackert, Markus W. BÃ¼chler, Nathalia Giese, Andrea Bauer, Thomas Muley, Arne Warth, Peter Schirmacher, Florian Haller, JÃ¶rg D. Hoheisel, Yasser Riazalhosseini

Published Dec 30, 2014 · Vol. 6, No. 6 · pp. 4418-4427

Keywords: DNA methylation, Cancer, Diagnosis, GHSR, Epigenetics

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

He Wang, Henghui Yin, Fengjiao Yan, Mingna Sun, Lingran Du, Wei Peng, Qiuli Li, Yinghong Feng, Yi Zhou

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 2827-2842

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA Research Paper

Anastassia Serguienko, Iwona Grad, Anna B. WennerstrÃ¸m, Leonardo A. Meza-Zepeda, Bernd Thiede, Eva W. Stratford, Ola Myklebost, Else Munthe

Published Dec 29, 2014 · Vol. 6, No. 4 · pp. 2451-2465

Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion Research Paper

Olga V. Leontieva, Mikhail V. Blagosklonny

Published Dec 29, 2014 · Vol. 5, No. 24 · pp. 12715-12727

Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression Research Paper

R. Mitchell Baldwin, Nasim Haghandish, Manijeh Daneshmand, Shahrier Amin, GeneviÃ¨ve Paris, Theresa J. Falls, John C. Bell, Shahidul Islam, Jocelyn CÃ´tÃ©

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3013-3032

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody Research Paper

Duane H. Hamilton, Romaine I. Fernando, Jeffrey Schlom, Claudia Palena

Published Dec 26, 2014 · Vol. 6, No. 7 · pp. 4853-4862

MYC is a critical target of FBXW7 Research Paper

Mai Sato, Ruth Rodriguez-Barrueco, Jiyang Yu, Catherine Do, Jose M. Silva, Jean Gautier

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3292-3305

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Loredana Vesci, Elena Bernasconi, Ferdinando Maria Milazzo, Rita De Santis, Eugenio Gaudio, Ivo Kwee, Andrea Rinaldi, Silvia Pace, Valeria Carollo, Giuseppe Giannini, Francesco Bertoni

Published Dec 25, 2014 · Vol. 6, No. 8 · pp. 5735-5748

Mastl kinase, a promising therapeutic target, promotes cancer recurrence Research Paper

Ling Wang, Vivian Q. Luong, Peter J. Giannini, Aimin Peng

Published Dec 22, 2014 · Vol. 5, No. 22 · pp. 11479-11489

Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS Research Paper

Barbie Taylor-Harding, Paul-Joseph Aspuria, Hasmik Agadjanian, Dong-Joo Cheon, Takako Mizuno, Danielle Greenberg, Jenieke R. Allen, Lindsay Spurka, Vincent Funari, Elizabeth Spiteri, Qiang Wang, Sandra Orsulic, Christine Walsh, Beth Y. Karlan, Ruprecht W. Wiedemeyer

Published Dec 22, 2014 · Vol. 6, No. 2 · pp. 696-714

Keywords: Cyclin-dependent kinase inhibitors, palbociclib, dinaciclib, Cyclin E1, ovarian cancer

MiR-125b regulates epithelial-mesenchymal transition via targeting Sema4C in paclitaxel-resistant breast cancer cells Research Paper

Qingling Yang, Yangyang Wang, Xiaohui Lu, Zunlan Zhao, Lihua Zhu, Sulian Chen, Qiong Wu, Changjie Chen, Zhiwei Wang

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3268-3279

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Lisha Xiang, Daniele M. Gilkes, Hongxia Hu, Naoharu Takano, Weibo Luo, Haiquan Lu, John W. Bullen, Debangshu Samanta, Houjie Liang, Gregg L. Semenza

Published Dec 18, 2014 · Vol. 5, No. 24 · pp. 12509-12527

Cyclin alterations in diverse cancers: Outcome and co-amplification network Research Paper

Maria Schwaederle, Gregory A. Daniels, David E. Piccioni, Paul T. Fanta, Richard B. Schwab, Kelly A. Shimabukuro, Barbara A. Parker, Razelle Kurzrock

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3033-3042

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Yu Fujita, Shigehiro Yagishita, Fumitaka Takeshita, Yusuke Yamamoto, Kazuyoshi Kuwano, Takahiro Ochiya

Published Dec 17, 2014 · Vol. 6, No. 5 · pp. 3335-3345

Keywords: RPN2, NSCLC, RNAi, siRNA, malignancy

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis Research Paper

Guobing Li, Jing Zhou, Amit Budhraja, Xiaoye Hu, Yibiao Chen, Qi Cheng, Lei Liu, Ting Zhou, Ping Li, Ehu Liu, Ning Gao

Published Dec 16, 2014 · Vol. 6, No. 3 · pp. 1834-1849

Keywords: Cofilin, Drp1, mitochondrial fission, erucin, apoptosis

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

Sixian Liang, Xun Peng, Xiaoli Li, Ping Yang, Linhao Xie, Yaochen Li, Caiwen Du, Guojun Zhang

Published Dec 11, 2014 · Vol. 6, No. 2 · pp. 1020-1030

Keywords: CXCR4, triple-negative breast cancer, cisplatin, chemosensitivity, apoptosis

By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy Research Paper

Annalisa Petrelli, Rosachiara Carollo, Marilisa Cargnelutti, Flora Iovino, Maurizio Callari, Daniela Cimino, Matilde Todaro, Laura Rosa Mangiapane, Alessandro Giammona, Adriana Cordova, Filippo Montemurro, Daniela Taverna, Maria Grazia Daidone, Giorgio Stassi, Silvia Giordano

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2315-2330

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Teeru Bihani, Scott A. Ezell, Brendon Ladd, Shaun E. Grosskurth, Anne Marie Mazzola, Mark Pietras, Corinne Reimer, Michael Zinda, Stephen Fawell, Celina M. Dâ€™Cruz

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2407-2420

Genetic alterations of histone lysine methyltransferases and their significance in breast cancer Research Paper

Lanxin Liu, Sarah Kimball, Hui Liu, Andreana Holowatyj, Zeng-Quan Yang

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2466-2482

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Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation Priority Research Paper

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA Research Paper

Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion Research Paper

Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression Research Paper

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody Research Paper

MYC is a critical target of FBXW7 Research Paper

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Mastl kinase, a promising therapeutic target, promotes cancer recurrence Research Paper

Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS Research Paper

MiR-125b regulates epithelial-mesenchymal transition via targeting Sema4C in paclitaxel-resistant breast cancer cells Research Paper

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Cyclin alterations in diverse cancers: Outcome and co-amplification network Research Paper

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis Research Paper

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy Research Paper

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Genetic alterations of histone lysine methyltransferases and their significance in breast cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation Priority Research Paper

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA Research Paper

Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion Research Paper

Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression Research Paper

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody Research Paper

MYC is a critical target of FBXW7 Research Paper

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Mastl kinase, a promising therapeutic target, promotes cancer recurrence Research Paper

Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS Research Paper

MiR-125b regulates epithelial-mesenchymal transition via targeting Sema4C in paclitaxel-resistant breast cancer cells Research Paper

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Cyclin alterations in diverse cancers: Outcome and co-amplification network Research Paper

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis Research Paper

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy Research Paper

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Genetic alterations of histone lysine methyltransferases and their significance in breast cancer Research Paper