The Oncosearch | Oncotarget

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway Research Paper

Jen-Chieh Lee, Shu Liu, Yucheng Wang, You Liang, David M. Jablons

Published Oct 26, 2022 · Vol. 13, No. 1 · pp. 1217-1236

Keywords: AML, CDK8, kinase inhibitor, STAT pathway, xenograft

Addendum: Exploration of the recurrence in radiation brain necrosis after bevacizumab discontinuation Addendum

Hongqing Zhuang, Xiangkun Yuan, Joe Y. Chang, Yongchun Song, Junjie Wang, Zhiyong Yuan, Xiaoguang Wang, Ping Wang

Published Oct 12, 2022

Addendum: Acquired-resistance of bevacizumab treatment for radiation brain necrosis: a case report Addendum

Hongqing Zhuang, Xiangkun Yuan, Dayong Sun, Jianliang Bian, Joe Y. Chang, Zhiyong Yuan, Ping Wang

Published Oct 12, 2022

Alectinib after failure to crizotinib in patients with ALK-positive non-small cell lung cancer: results from the Spanish early access program Research Paper

Reyes Bernabé-Caro, Pilar Garrido, Rosario García-Campelo, Ramón Palmero, Ángel Artal, Cristina Bayona, Delvys Rodríguez-Abreu, Marta López-Brea, Alfredo Paredes, David Vicente, José Miguel Sánchez Torres, Margarita Majem, Pilar Diz, Rocío Gordo, Margarita Coca, Javier de Castro

Published Jun 7, 2022 · Vol. 13, No. 1 · pp. 812-827

Keywords: ALK-positive NSCLC, ALK inhibitor, crizotinib, alectinib, unselected patient

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Laura Valdez, Benxu Cheng, Daniela Gonzalez, Reanna Rodriguez, Paola Campano, Andrew Tsin, Xiaoqian Fang

Published Apr 22, 2022 · Vol. 13, No. 1 · pp. 642-658

Keywords: glioblastoma, niclosamide, camptothecin, cancer, chemotherapy

Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma Case Report

Eugene J. Vaios, Kristen A. Batich, Anne F. Buckley, Anastasie Dunn-Pirio, Mallika P. Patel, John P. Kirkpatrick, Ranjit Goudar, Katherine B. Peters

Published Mar 15, 2022 · Vol. 13, No. 1 · pp. 576-582

Keywords: radiation necrosis, brain tumor, primary CNS lymphoma, stereotactic radiosurgery, bevacizumab

A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo Research Paper

Mark H. Murdock, George S. Hussey, Jordan T. Chang, Ryan C. Hill, David G. Nascari, Aparna V. Rao, Kirk C. Hansen, Lesley M. Foley, T. Kevin Hitchens, Nduka M. Amankulor, Stephen F. Badylak

Published Feb 16, 2022 · Vol. 13, No. 1 · pp. 426-438

Keywords: extracellular matrix, brain cancer, glioma treatment, dynamic reciprocity, tissue organization field theory

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Sydney Weber Boutros, Destine Krenik, Sarah Holden, Vivek K. Unni, Jacob Raber

Published Jan 14, 2022 · Vol. 13, No. 1 · pp. 198-213

Keywords: amifostine, etoposide, double strand breaks, memory, sex

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

Nicholas Cho, Sooah Ko, Monica Shokeen

Published Sep 7, 2021 · Vol. 12, No. 20 · pp. 2039-2050

Keywords: near-infrared (NIR) fluorescence, multiple myeloma (MM), cluster of differentiation 38 (CD38), antibody-drug conjugate (ADC), small animal optical imaging

Role of microRNAs in glioblastoma Review

Ming Chen, Zdravka Medarova, Anna Moore

Published Jul 30, 2021 · Vol. 12, No. 17 · pp. 1707-1723

Keywords: glioblastoma, microRNA, miRNA-based therapies, miRNA delivery

Delivering albumin-bound paclitaxel across the blood-brain barrier for gliomas Editorial

Andrew Gould, Daniel Zhang, Víctor A. Arrieta, Roger Stupp, Adam M. Sonabend

Published Jun 24, 2021 · Vol. 12, No. 25 · pp. 2474-2475

Keywords: glioblastoma, focused ultrasound, blood brain barrier, paclitaxel

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Lina Alhalhooly, Babak Mamnoon, Jiha Kim, Sanku Mallik, Yongki Choi

Published May 20, 2021 · Vol. 12, No. 12 · pp. 1165-1177

Keywords: cellular stiffness, roughness, adhesion, drug resistance, hypoxia

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cells Research Paper

Marpe Bam, Sreenivasulu Chintala, Kaleigh Fetcko, Brooke Carmen Williamsen, Seema Siraj, Sheng Liu, Jun Wan, Xiaoling Xuei, Yunlong Liu, Adam T. Leibold, Mahua Dey

Published Apr 25, 2021 · Vol. 12, No. 10 · pp. 967-981

Keywords: glioblastoma, malignant glioma, CD4+ T cell, DNA methylation, brain cancer

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Aditya Kulkarni, Joseph Ryan McDermott, Umesh Kathad, Rama Modali, Jean-Philippe Richard, Panna Sharma, Kishor Bhatia

Published Apr 5, 2021 · Vol. 12, No. 8 · pp. 791-806

Keywords: non-small cell lung cancer, acylfulvene, alkylating agent, PTGR1, LP-184

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Sateja Paradkar, James Herrington, Adam Hendricson, Piyasena Hewawasam, Mark Plummer, Denton Hoyer, Ranjini K. Sundaram, Yulia V. Surovtseva, Ranjit S. Bindra

Published Mar 27, 2021 · Vol. 12, No. 9 · pp. 891-906

Keywords: glioblastoma, radiosensitizers, mibefradil, DNA repair, alternative non-homologous end joining

Polo-like kinase inhibition as a therapeutic target in acute myeloid leukemia Research Perspective

Jan Philipp Bewersdorf, Amer M. Zeidan

Published Mar 11, 2021 · Vol. 12, No. 13 · pp. 1314-1317

Keywords: acute myeloid leukemia, AML, PLK-1 inhibitor, onvansertib, volasertib

Is there a role for CDK 4/6 inhibitors in breast cancer brain metastases? Editorial

Ilana Schlam, Sara M. Tolaney

Published Feb 19, 2021 · Vol. 12, No. 9 · pp. 873-875

Keywords: breast cancer, brain metastasis, leptomeningeal disease, CDK 4/6 inhibitors

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

H.M.C. Shantha Kumara, Elie Sutton, Otavia L. Caballero, Tao Su, Xiaohong Yan, Aqeel Ahmed, Sonali A.C. Herath, Vesna Cekic, Linda Njoh, Daniel D. Kirchoff, Richard L. Whelan

Published Feb 9, 2021 · Vol. 12, No. 5 · pp. 412-421

Keywords: cancer testis antigens, colorectal cancer, CABYR a/b, c

Low concentrations of vorinostat decrease EB1 expression in GBM cells and affect microtubule dynamics, cell survival and migration Research Paper

Thomas Perez, Raphaël Bergès, Hélène Maccario, Sarah Oddoux, Stéphane Honoré

Published Feb 5, 2021 · Vol. 12, No. 4 · pp. 304-315

Keywords: vorinostat, glioblastoma, EB1, microtubule, tubulin

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

Karam Khaddour, Joshua Dowling, Jiayi Huang, Martha Council, David Chen, Lynn Cornelius, Tanner Johanns, Sonika Dahiya, George Ansstas

Published Dec 13, 2020 · Vol. 11, No. 52 · pp. 4836-4844

Keywords: metastatic melanoma, immune checkpoint inhibitor, temozolomide, acquired resistance, beta-2 microglobulin

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MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway Research Paper

Addendum: Exploration of the recurrence in radiation brain necrosis after bevacizumab discontinuation Addendum

Addendum: Acquired-resistance of bevacizumab treatment for radiation brain necrosis: a case report Addendum

Alectinib after failure to crizotinib in patients with ALK-positive non-small cell lung cancer: results from the Spanish early access program Research Paper

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma Case Report

A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo Research Paper

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

Role of microRNAs in glioblastoma Review

Delivering albumin-bound paclitaxel across the blood-brain barrier for gliomas Editorial

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cells Research Paper

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Polo-like kinase inhibition as a therapeutic target in acute myeloid leukemia Research Perspective

Is there a role for CDK 4/6 inhibitors in breast cancer brain metastases? Editorial

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

Low concentrations of vorinostat decrease EB1 expression in GBM cells and affect microtubule dynamics, cell survival and migration Research Paper

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway Research Paper

Addendum: Exploration of the recurrence in radiation brain necrosis after bevacizumab discontinuation Addendum

Addendum: Acquired-resistance of bevacizumab treatment for radiation brain necrosis: a case report Addendum

Alectinib after failure to crizotinib in patients with ALK-positive non-small cell lung cancer: results from the Spanish early access program Research Paper

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma Case Report

A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo Research Paper

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

Role of microRNAs in glioblastoma Review

Delivering albumin-bound paclitaxel across the blood-brain barrier for gliomas Editorial

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cells Research Paper

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Polo-like kinase inhibition as a therapeutic target in acute myeloid leukemia Research Perspective

Is there a role for CDK 4/6 inhibitors in breast cancer brain metastases? Editorial

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

Low concentrations of vorinostat decrease EB1 expression in GBM cells and affect microtubule dynamics, cell survival and migration Research Paper

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report