The Oncosearch | Oncotarget

Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells Research Paper

Azusa Tanimoto, Tadaaki Yamada, Shigeki Nanjo, Shinji Takeuchi, Hiromichi Ebi, Kenji Kita, Kunio Matsumoto, Seiji Yano

Published Jun 3, 2014 · Vol. 5, No. 13 · pp. 4920-4928

HGF/c-Met axis drives cancer aggressiveness in the neo-adjuvant setting of ovarian cancer Research Paper

Marisa Mariani, Mark McHugh, Marco Petrillo, Steven Sieber, Shiquan He, Mirko Andreoli, Zheyang Wu, Paul Fiedler, Giovanni Scambia, Shohreh Shahabi, Cristiano Ferlini

Published Jun 1, 2014 · Vol. 5, No. 13 · pp. 4855-4867

Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment Research Paper

Yumay Chen, Chi-Fen Chen, Rosaria Polci, Randy Wei, Daniel J. Riley, Phang-Lang Chen

Published May 25, 2014 · Vol. 5, No. 12 · pp. 4283-4294

Cripto-1 as a novel therapeutic target for triple negative breast cancer Priority Research Paper

Nadia P. Castro, Natalie D. Fedorova-Abrams, Anand S. Merchant, Maria Cristina Rangel, Tadahiro Nagaoka, Hideaki Karasawa, Malgorzata Klauzinska, Stephen M. Hewitt, Kajal Biswas, Shyam K. Sharan, David S. Salomon

Published May 19, 2014 · Vol. 6, No. 14 · pp. 11910-11929

BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease Research Paper

Filip Janku, Cecile Rose T. Vibat, Karena Kosco, Veronica R. Holley, Goran Cabrilo, Funda Meric-Bernstam, Vanda M. Stepanek, Patrick P. Lin, Lorieta Leppin, Latifa Hassaine, Jason C. Poole, Razelle Kurzrock, Mark G. Erlander

Published May 13, 2014 · Vol. 5, No. 11 · pp. 3607-3610

Anti-neoplastic properties of hydralazine in prostate cancer Research Paper

InÃªs GraÃ§a, Elsa J. Sousa, Pedro Costa-Pinheiro, Filipa Q. Vieira, Jorge Torres-Ferreira, Maria Gabriela Martins, Rui Henrique, Carmen JerÃ³nimo

Published Apr 17, 2014 · Vol. 5, No. 15 · pp. 5950-5964

RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis Research Paper

Mathias Dahlmann, Anna Okhrimenko, Patrick Marcinkowski, Marc Osterland, Pia Herrmann, Janice Smith, Claus W. Heizmann, Peter M. Schlag, Ulrike Stein

Published Apr 17, 2014 · Vol. 5, No. 10 · pp. 3220-3233

âˆ†N-P63Î± and TA-P63Î± exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. Research Paper

Paola Monti, Yari Ciribilli, Alessandra Bisio, Giorgia Foggetti, Ivan Raimondi, Paola Campomenosi, Paola Menichini, Gilberto Fronza, Alberto Inga

Published Mar 23, 2014 · Vol. 5, No. 8 · pp. 2116-2130

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

Jinquan Cai, Pei Yang, Chuanbao Zhang, Wei Zhang, Yanwei Liu, Zhaoshi Bao, Xing Liu, Wenzhong Du, Hongjun Wang, Tao Jiang, Chuanlu Jiang

Published Mar 21, 2014 · Vol. 5, No. 9 · pp. 2551-2561

WT1 regulates angiogenesis in Ewing Sarcoma Research Paper

Varalakshimi Katuri, Stephanie Gerber, Xiaofei Qiu, Gregory McCarty, Seth D. Goldstein, Hans Hammers, Elizabeth Montgomery, Allen R. Chen, David M. Loeb

Published Feb 3, 2014 · Vol. 5, No. 9 · pp. 2436-2449

Keywords: tumor angiogenesis, transcriptional regulation, tissue microarray, vascularity, alternative splicing

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Jakob H. Mikkelsen, Zachary T. Resch, Bhanu Kalra, Gopal Savjani, Ajay Kumar, Cheryl A. Conover, Claus Oxvig

Published Jan 17, 2014 · Vol. 5, No. 4 · pp. 1014-1025

Keywords: insulin-like growth factor receptor, pregnancy-associated plasma protein-A, proteolytic inhibition, therapeutic antibody, xenograft mouse model

Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway Research Paper

Bahityar Rahmutulla, Kazuyuki Matsushita, Mamoru Satoh, Masanori Seimiya, Sachio Tsuchida, Shuji Kubo, Hideaki Shimada, Masayuki Ohtsuka, Masaru Miyazaki, Fumio Nomura

Published Dec 21, 2013 · Vol. 5, No. 9 · pp. 2404-2417

Keywords: FBP interacting repressor (FIR), bleomycin, DNA damage, Ku86, c-Myc, P27Kip1

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-ÎºB regulated gene products in multiple myeloma xenograft mouse model Research Paper

Kodappully Sivaraman Siveen, Nurulhuda Mustafa, Feng Li, Radhamani Kannaiyan, Kwang Seok Ahn, Alan Prem Kumar, Wee-Joo Chng, Gautam Sethi

Published Dec 18, 2013 · Vol. 5, No. 3 · pp. 634-648

Keywords: Thymoquinone, MM, bortezomib, apoptosis, NF-ÎºB

Resistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming Research Paper

Veronica Martinez-Marignac, Nader Toban, Miguel Bazile, Raquel Aloyz

Published Nov 7, 2013 · Vol. 4, No. 12 · pp. 2550-2566

Keywords: CLL, AMPK, Dasatinib, kinase inhibitor, metabolism, glycolysis, OXPHOS

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Jennifer Munkley, Prabhakar Rajan, Nicholas P. Lafferty, Caroline Dalgliesh, Robert M. Jackson, Craig N. Robson, Hing Y. Leung, David J. Elliott

Published Oct 21, 2013 · Vol. 5, No. 1 · pp. 131-139

Keywords: TSC2, mTOR, mRNA isoform, androgen, prostate cancer

Induction of apoptosis by directing oncogenic Bcr-Abl into the nucleus Research Paper

Zheng-Lan Huang, Miao Gao, Qian-Yin Li, Kun Tao, Qing Xiao, Wei-Xi Cao, Wen-Li Feng

Published Oct 9, 2013 · Vol. 4, No. 12 · pp. 2249-2260

Keywords: chronic myeloid leukemia, Bcr-Abl, nuclear localization, rapalog, apoptosis

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers Research Paper

Shruti Desai, Minming Ding, Bin Wang, Zhimin Lu, Qi Zhao, Kenna Shaw, W K Alfred Yung, John N Weinstein, Ming Tan, Jun Yao

Published Aug 7, 2013 · Vol. 5, No. 18 · pp. 8202-8210

Keywords: PKM2, alternative splicing, DNA methylation

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients Research Paper

Marc Delord, Philippe Rousselot, Jean-Michel Cayuela, FranÃ§ois Sigaux, JoÃ«lle Guilhot, Claude Preudhomme, FranÃ§ois Guilhot, Pascale Loiseau, Emmanuel Raffoux, Daniela Geromin, Emmanuelle Genin, Fabien Calvo, Heriberto Bruzzoni-Giovanelli

Published Jul 18, 2013 · Vol. 4, No. 10 · pp. 1582-1591

Keywords: CML, Imatinib, SNPs, ABCG2, Pharmacogenetic, molecular response, BCR-ABL

Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations Research Paper

Jonathan M. Gerber, Jessica L. Gucwa, David Esopi, Meltem Gurel, Michael C. Haffner, Milada Vala, William G. Nelson, Richard J. Jones, Srinivasan Yegnasubramanian

Published May 6, 2013 · Vol. 4, No. 5 · pp. 715-728

Keywords: chronic myeloid leukemia, CML, leukemic stem cell, LSC, normal hematopoietic stem cell, HSC, myeloid progenitor cells, CD34, CD38, ALDH, IL2RA, CD25, DPP4, CD26, GAS2

Drug-Loaded Nanoparticle Systems And Adult Stem Cells: A Potential Marriage For The Treatment Of Malignant Glioma? Review

Brenda Auffinger, Ramin Morshed, Alex Tobias, Yu Cheng, Atique U Ahmed, Maciej S Lesniak

Published Mar 26, 2013 · Vol. 4, No. 3 · pp. 378-396

Keywords: Nanoparticle, drug delivery systems, stem cell carriers, malignant glioma, brain cancer, targeted delivery

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Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells Research Paper

HGF/c-Met axis drives cancer aggressiveness in the neo-adjuvant setting of ovarian cancer Research Paper

Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment Research Paper

Cripto-1 as a novel therapeutic target for triple negative breast cancer Priority Research Paper

BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease Research Paper

Anti-neoplastic properties of hydralazine in prostate cancer Research Paper

RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis Research Paper

âˆ†N-P63Î± and TA-P63Î± exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. Research Paper

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

WT1 regulates angiogenesis in Ewing Sarcoma Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway Research Paper

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-ÎºB regulated gene products in multiple myeloma xenograft mouse model Research Paper

Resistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Induction of apoptosis by directing oncogenic Bcr-Abl into the nucleus Research Paper

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers Research Paper

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients Research Paper

Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations Research Paper

Drug-Loaded Nanoparticle Systems And Adult Stem Cells: A Potential Marriage For The Treatment Of Malignant Glioma? Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells Research Paper

HGF/c-Met axis drives cancer aggressiveness in the neo-adjuvant setting of ovarian cancer Research Paper

Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment Research Paper

Cripto-1 as a novel therapeutic target for triple negative breast cancer Priority Research Paper

BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease Research Paper

Anti-neoplastic properties of hydralazine in prostate cancer Research Paper

RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis Research Paper

âˆ†N-P63Î± and TA-P63Î± exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. Research Paper

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

WT1 regulates angiogenesis in Ewing Sarcoma Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway Research Paper

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-ÎºB regulated gene products in multiple myeloma xenograft mouse model Research Paper

Resistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Induction of apoptosis by directing oncogenic Bcr-Abl into the nucleus Research Paper

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers Research Paper

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients Research Paper

Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations Research Paper

Drug-Loaded Nanoparticle Systems And Adult Stem Cells: A Potential Marriage For The Treatment Of Malignant Glioma? Review