The Oncosearch | Oncotarget

Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog Research Paper

Bhairavi Tolani, Ngoc T. Hoang, Luis A. Acevedo, Etienne Giroux Leprieur, Hui Li, Biao He, David M. Jablons

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14311-14323

Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma Research Paper

Aidan M. Rose, Lindsay C. Spender, Christopher Stephen, Alastair Mitchell, William Rickaby, Susan Bray, Alan T. Evans, Jasbani Dayal, Karin J. Purdie, Catherine A. Harwood, Charlotte M Proby, Irene M. Leigh, Philip J. Coates, Gareth J. Inman

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14552-14566

RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer Research Paper

Madhura Kulkarni, Tuan Zea Tan, Nurfarhanah Bte Syed Sulaiman, John M. Lamar, Prashali Bansal, Jianzhou Cui, Yiting Qiao, Yoshiaki Ito

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14175-14192

Predictive value of inflammation-based prognostic scores in patients with metastatic renal cell carcinoma treated with cytoreductive nephrectomy Research Paper

Hironori Fukuda, Toshio Takagi, Tsunenori Kondo, Satoru Shimizu, Kazunari Tanabe

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14296-14305

Doxorubicin-induced loss of DNA topoisomerase II and DNMT1- dependent suppression of MiR-125b induces chemoresistance in ALK-positive cells Research Paper

Annabelle Congras, Nina Caillet, Nouritza Torossian, Cathy Quelen, Camille Daugrois, Pierre Brousset, Laurence Lamant, Fabienne Meggetto, Coralie Hoareau-Aveilla

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14539-14551

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma Research Paper

Yu Tanabe, Yoshiyuki Suehara, Shinji Kohsaka, Takuo Hayashi, Keisuke Akaike, Kenta Mukaihara, Taisei Kurihara, Youngji Kim, Taketo Okubo, Midori Ishii, Saiko Kazuno, Kazuo Kaneko, Tsuyoshi Saito

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14428-14443

A single digital droplet PCR assay to detect multiple KIT exon 11 mutations in tumor and plasma from patients with gastrointestinal stromal tumors Research Paper

Pieter A. Boonstra, Arja ter Elst, Marco Tibbesma, Lisette J. Bosman, Ron Mathijssen, Florence Atrafi, Frits van Coevorden, Neeltje Steeghs, Sheima Farag, Hans Gelderblom, Winette T.A. van der Graaf, Ingrid M.E. Desar, Jacqueline Maier, Jelle Overbosch, Albert J.H. Suurmeijer, Jourik Gietema, Ed Schuuring, An K.L. Reyners

Published Feb 14, 2018 · Vol. 9, No. 17 · pp. 13870-13883

Bcl-xL as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in BRAF-mutant stage II and III colon cancer Research Paper

Philip D. Dunne, Helen G. Coleman, Peter Bankhead, Matthew Alderdice, Ronan T. Gray, Stephen McQuaid, Victoria Bingham, Maurice B. Loughrey, Jacqueline A. James, Amy M.B. McCorry, Alan Gilmore, Caitriona Holohan, Dirk Klingbiel, Sabine Tejpar, Patrick G. Johnston, Darragh G. McArt, Federica Di Nicolantonio, Daniel B. Longley, Mark Lawler

Published Feb 13, 2018 · Vol. 9, No. 17 · pp. 13834-13847

Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors Research Paper

Sergey Malchenko, Simone T. Sredni, Jerusha Boyineni, Yingtao Bi, Naira V. Margaryan, Maheedhara R. Guda, Yulia Kostenko, Tadanori Tomita, Ramana V. Davuluri, Kiran Velpula, Mary J.C. Hendrix, Marcelo B. Soares

Published Feb 9, 2018 · Vol. 9, No. 17 · pp. 13733-13747

IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner Research Paper

Romy Loschinski, Martin BÃ¶ttcher, Andrej Stoll, Heiko Bruns, Andreas Mackensen, Dimitrios Mougiakakos

Published Feb 7, 2018 · Vol. 9, No. 17 · pp. 13125-13138

Leukocyte telomere length throughout the continuum of colorectal carcinogenesis Research Paper

Cornelia ZÃ¶chmeister, Stefanie Brezina, Philipp Hofer, Andreas Baierl, Michael M. Bergmann, Thomas Bachleitner-Hofmann, Judith Karner-Hanusch, Anton Stift, Armin Gerger, Gernot Leeb, Karl Mach, Sivaramakrishna Rachakonda, Rajiv Kumar, Andrea Gsur

Published Feb 7, 2018 · Vol. 9, No. 17 · pp. 13582-13592

Hsa-miR-155-5p drives aneuploidy at early stages of cellular transformation Research Paper

Sara Pagotto, Angelo Veronese, Alessandra Soranno, Paola Lanuti, Mirco Di Marco, Marco Vincenzo Russo, Alice Ramassone, Marco Marchisio, Pasquale Simeone, Paolo E. Guanciali Franchi, Giandomenico Palka, Renato Mariani Costantini, Carlo M. Croce, Rosa Visone

Published Feb 7, 2018 · Vol. 9, No. 16 · pp. 13036-13047

Deregulation of linc-PINT in acute lymphoblastic leukemia is implicated in abnormal proliferation of leukemic cells Research Paper

Andoni Garitano-Trojaola, Edurne San JosÃ©-EnÃ©riz, Teresa Ezponda, Juan Pablo Unfried, Arantxa Carrasco-LeÃ³n, Nerea Razquin, Marina Barriocanal, Amaia Vilas-Zornoza, Bruno Sangro, Victor Segura, Felipe PrÃ³sper, Puri Fortes, Xabier Agirre

Published Feb 5, 2018 · Vol. 9, No. 16 · pp. 12842-12852

The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis Research Paper

Johaiber Fuchslocher Chico, Maren Falk-Paulsen, Anne Luzius, Carina Saggau, Barbara Ruder, Julia Bolik, Dirk Schmidt-Arras, Andreas Linkermann, Christoph Becker, Philip Rosenstiel, Stefan Rose-John, Dieter Adam

Published Feb 5, 2018 · Vol. 9, No. 16 · pp. 12941-12958

The Yin and Yang of regulatory T cells in immunotherapy Editorial

Yan Li, James P. Di Santo

Published Feb 3, 2018 · Vol. 9, No. 13 · pp. 10828-10829

Combined modality radiation therapy promotes tolerogenic myeloid cell populations and STAT3-related gene expression in head and neck cancer patients Research Paper

Sagus Sampath, Haejung Won, Erminia Massarelli, Min Li, Paul Frankel, Nayana Vora, Lalit Vora, Ellie Maghami, Marcin Kortylewski

Published Feb 2, 2018 · Vol. 9, No. 13 · pp. 11279-11290

Regulatory effects of Nr4a2 on Th2 cells from patients with pemphigus vulgaris Research Paper

Jianbo Chen, Yao Zhang, Yunsheng Liang, Ming Zhao, Hai Long, Rong Xiao, Haijing Wu, Jieyue Liao, Shuaihantian Luo, Guiying Zhang, Qianjin Lu

Published Feb 1, 2018 · Vol. 9, No. 13 · pp. 11258-11267

Dasatinib overrides the differentiation blockage in a patient with mutant-KIT D816V positive CBFβ-MYH11 leukemia Case Report

Kerstin M. Kampa-Schittenhelm, Wichard Vogel, Irina Bonzheim, Falko Fend, Marius Horger, Lothar Kanz, Martin Soekler, Marcus M. Schittenhelm

Published Jan 31, 2018 · Vol. 9, No. 14 · pp. 11876-11882

Novel adherent CD11b⁺ Gr-1⁺ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment Research Paper

Takuya Tsubaki, Tetsuya Kadonosono, Shimon Sakurai, Tadashi Shiozawa, Toshiki Goto, Shiori Sakai, Takahiro Kuchimaru, Takeharu Sakamoto, Hitomi Watanabe, Gen Kondoh, Shinae Kizaka-Kondoh

Published Jan 29, 2018 · Vol. 9, No. 13 · pp. 11209-11226

Impact on early outcomes and immune reconstitution of high-dose post-transplant cyclophosphamide vs anti-thymocyte globulin after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation Research Paper

Christelle RetiÃ¨re, Catherine Willem, Thierry Guillaume, Henri ViÃ©, Laetitia Gautreau-Rolland, Emmanuel Scotet, Xavier Saulquin, Katia Gagne, Marie C. BÃ©nÃ©, Berthe-Marie Imbert, Beatrice Clemenceau, Pierre Peterlin, Alice Garnier, Patrice Chevallier

Published Jan 27, 2018 · Vol. 9, No. 14 · pp. 11451-11464

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Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog Research Paper

Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma Research Paper

RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer Research Paper

Predictive value of inflammation-based prognostic scores in patients with metastatic renal cell carcinoma treated with cytoreductive nephrectomy Research Paper

Doxorubicin-induced loss of DNA topoisomerase II and DNMT1- dependent suppression of MiR-125b induces chemoresistance in ALK-positive cells Research Paper

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma Research Paper

A single digital droplet PCR assay to detect multiple KIT exon 11 mutations in tumor and plasma from patients with gastrointestinal stromal tumors Research Paper

Bcl-xL as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in BRAF-mutant stage II and III colon cancer Research Paper

Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors Research Paper

IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner Research Paper

Leukocyte telomere length throughout the continuum of colorectal carcinogenesis Research Paper

Hsa-miR-155-5p drives aneuploidy at early stages of cellular transformation Research Paper

Deregulation of linc-PINT in acute lymphoblastic leukemia is implicated in abnormal proliferation of leukemic cells Research Paper

The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis Research Paper

The Yin and Yang of regulatory T cells in immunotherapy Editorial

Combined modality radiation therapy promotes tolerogenic myeloid cell populations and STAT3-related gene expression in head and neck cancer patients Research Paper

Regulatory effects of Nr4a2 on Th2 cells from patients with pemphigus vulgaris Research Paper

Dasatinib overrides the differentiation blockage in a patient with mutant-KIT D816V positive CBFβ-MYH11 leukemia Case Report

Novel adherent CD11b⁺ Gr-1⁺ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment Research Paper

Impact on early outcomes and immune reconstitution of high-dose post-transplant cyclophosphamide vs anti-thymocyte globulin after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog Research Paper

Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma Research Paper

RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer Research Paper

Predictive value of inflammation-based prognostic scores in patients with metastatic renal cell carcinoma treated with cytoreductive nephrectomy Research Paper

Doxorubicin-induced loss of DNA topoisomerase II and DNMT1- dependent suppression of MiR-125b induces chemoresistance in ALK-positive cells Research Paper

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma Research Paper

A single digital droplet PCR assay to detect multiple KIT exon 11 mutations in tumor and plasma from patients with gastrointestinal stromal tumors Research Paper

Bcl-xL as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in BRAF-mutant stage II and III colon cancer Research Paper

Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors Research Paper

IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner Research Paper

Leukocyte telomere length throughout the continuum of colorectal carcinogenesis Research Paper

Hsa-miR-155-5p drives aneuploidy at early stages of cellular transformation Research Paper

Deregulation of linc-PINT in acute lymphoblastic leukemia is implicated in abnormal proliferation of leukemic cells Research Paper

The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis Research Paper

The Yin and Yang of regulatory T cells in immunotherapy Editorial

Combined modality radiation therapy promotes tolerogenic myeloid cell populations and STAT3-related gene expression in head and neck cancer patients Research Paper

Regulatory effects of Nr4a2 on Th2 cells from patients with pemphigus vulgaris Research Paper

Dasatinib overrides the differentiation blockage in a patient with mutant-KIT D816V positive CBFβ-MYH11 leukemia Case Report

Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment Research Paper

Impact on early outcomes and immune reconstitution of high-dose post-transplant cyclophosphamide vs anti-thymocyte globulin after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation Research Paper

Novel adherent CD11b⁺ Gr-1⁺ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment Research Paper