The Oncosearch | Oncotarget

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

Tiansuo Zhao, He Ren, Li Jia, Jing Chen, Wen Xin, Fan Yan, Jing Li, Xiuchao Wang, Song Gao, Dong Qian, Chongbiao Huang, Jihui Hao

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2250-2262

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells Research Paper

Cordula A. Jilg, Anett Ketscher, Eric Metzger, Barbara Hummel, Dominica Willmann, Vanessa RÃ¼sseler, Vanessa Drendel, Axel Imhof, Manfred Jung, Henriette Franz, Stefanie HÃ¶lz, Malte KrÃ¶nig, Judith M. MÃ¼ller, Roland SchÃ¼le

Published Dec 10, 2014 · Vol. 5, No. 24 · pp. 12646-12664

Î±-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma Research Paper

Katharina Teiluf, Christof Seidl, Birgit Blechert, Florian C. Gaertner, Klaus-Peter Gilbertz, Vanesa Fernandez, Florian Bassermann, Jan Endell, Rainer Boxhammer, Stephane Leclair, Mario Vallon, Michaela Aichler, Annette Feuchtinger, Frank Bruchertseifer, Alfred Morgenstern, Markus Essler

Published Dec 10, 2014 · Vol. 6, No. 7 · pp. 4692-4703

Î²III-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer Research Paper

Joshua A. McCarroll, George Sharbeen, Jie Liu, Janet Youkhana, David Goldstein, Nigel McCarthy, Lydia F. Limbri, Dominic Dischl, GÃ¼ralp O. Ceyhan, Mert Erkan, Amber L. Johns, Andrew V. Biankin, Maria Kavallaris, Phoebe A. Phillips

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2235-2249

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma Research Paper

Stephen Q. Wong, Andreas Behren, Victoria J. Mar, Katherine Woods, Jason Li, Claire Martin, Karen E. Sheppard, Rory Wolfe, John Kelly, Jonathan Cebon, Alexander Dobrovic, Grant A. McArthur

Published Dec 6, 2014 · Vol. 6, No. 2 · pp. 1115-1127

Keywords: Melanoma, RQCD1, exome sequencing

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells Research Paper

Bo-Ra Lee, Sun-Young Chang, Eun-Hye Hong, Bo-Eun Kwon, Hong Min Kim, Yeon-Jeong Kim, Jongkook Lee, Hyun-Jong Cho, Jae-Hee Cheon, Hyun-Jeong Ko

Published Dec 2, 2014 · Vol. 5, No. 23 · pp. 12331-12345

Keywords: cancer, ER stress, MDSC, immunosuppression, arginase-1

PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies Clinical Research Papers

Matthias Scheffler, Marc Bos, Masyar Gardizi, Katharina KÃ¶nig, Sebastian Michels, Jana Fassunke, Carina Heydt, Helen KÃ¼nstlinger, Michaela Ihle, Frank Ueckeroth, Kerstin Albus, Monika Serke, Ulrich Gerigk, Wolfgang Schulte, Karin TÃ¶pelt, Lucia Nogova, Thomas Zander, Walburga Engel-Riedel, Erich Stoelben, Yon-Dschun Ko, Winfried Randerath, Britta Kaminsky, Jens Panse, Carolin Becker, Martin Hellmich, Sabine Merkelbach-Bruse, Lukas C. Heukamp, Reinhard BÃ¼ttner, JÃ¼rgen Wolf

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1315-1326

Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models Research Paper

Huanzhang Hu, Yinghe Qiu, Minggao Guo, Yao Huang, Lin Fang, Zhangxiao Peng, Weidan Ji, Yang Xu, Shuwen Shen, Yan Yan, Xuandong Huang, Junnian Zheng, Changqing Su

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1079-1089

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA Research Paper

Hongxin Ma, Xuetian Yue, Lifen Gao, Xiaohong Liang, Wenjiang Yan, Zhenyu Zhang, Haixia Shan, Hualin Zhang, Brett T. Spear, Chunhong Ma

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1049-1063

An HSV-2 based oncolytic virus can function as an attractant to guide migration of adoptively transferred T cells to tumor sites Research Paper

Xinping Fu, Armando Rivera, Lihua Tao, Xiaoliu Zhang

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 902-914

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer Priority Research Paper

Frank P. Vendetti, Michael Topper, Peng Huang, Irina Dobromilskaya, Hariharan Easwaran, John Wrangle, Stephen B. Baylin, J. T. Poirier, Charles M. Rudin

Published Nov 25, 2014 · Vol. 6, No. 1 · pp. 56-70

Keywords: epigenetic, azacitidine, entinostat, priming, chemosensitivity, non-small cell lung cancer (NSCLC)

The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma Research Paper

Emmy D.G. Fleuren, Melissa H.S. Hillebrandt-Roeffen, Uta E. Flucke, D. Maroeska W.M. te Loo, Otto C. Boerman, Winette T.A. van der Graaf, Yvonne M.H. Versleijen-Jonkers

Published Nov 15, 2014 · Vol. 5, No. 24 · pp. 12753-12768

Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57 Research Paper

Xuekai Zhu, Shruthi Prasad, Simone Gaedicke, Michael Hettich, Elke Firat, Gabriele Niedermann

Published Nov 15, 2014 · Vol. 6, No. 1 · pp. 171-184

LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myeloma-bone disease Research Paper

Giacomina Brunetti, Rita Rizzi, Angela Oranger, Isabella Gigante, Giorgio Mori, Grazia Taurino, Teresa Mongelli, Graziana Colaianni, Adriana Di Benedetto, Roberto Tamma, Giuseppe Ingravallo, Anna Napoli, Maria Felicia Faienza, Anna Mestice, Paola Curci, Giorgina Specchia, Silvia Colucci, Maria Grano

Published Nov 12, 2014 · Vol. 5, No. 24 · pp. 12950-12967

Keywords: LIGHT/TNFSF14, Multiple Myeloma, Bone disease, Osteoclast, Osteoblast

Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkinâ€™s lymphomas Research Paper

Rita Lh Yim, Kwan Yeung Wong, Yok Lam Kwong, Florence Loong, Chung Ying Leung, Raymond Chu, William W. Lam, Pak Kwan Hui, Raymond Lai, Chor Sang Chin

Published Nov 11, 2014 · Vol. 5, No. 20 · pp. 9770-9782

IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival Clinical Research Papers

Serena Lunardi, Nigel B. Jamieson, Su Yin Lim, Kristin L. Griffiths, Manuela Carvalho-Gaspar, Osama Al-Assar, Sabira Yameen, Ross C. Carter, Colin J. McKay, Gabriele Spoletini, Stefano Dâ€™Ugo, Michael A. Silva, Owen J. Sansom, Klaus-Peter Janssen, Ruth J. Muschel, Thomas B. Brunner

Published Nov 11, 2014 · Vol. 5, No. 22 · pp. 11064-11080

PD-L1 is highly expressed in Enzalutamide resistant prostate cancer Research Paper

Jennifer L. Bishop, Alexander Sio, Arkhjamil Angeles, Morgan E. Roberts, Arun A. Azad, Kim N. Chi, Amina Zoubeidi

Published Nov 6, 2014 · Vol. 6, No. 1 · pp. 234-242

Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue Priority Research Paper

Kerstin A. David, Florian T. Unger, Philipp Uhlig, Hartmut Juhl, Helen M. Moore, Carolyn Compton, BjÃ¶rn Nashan, Arnulf DÃ¶rner, Andreas de Weerth, Carsten Zornig

Published Nov 3, 2014 · Vol. 5, No. 22 · pp. 11017-11028

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis Research Paper

Catherine E. Waters, Joshua C. Saldivar, Zaynab A. Amin, Morgan S. Schrock, Kay Huebner

Published Oct 31, 2014 · Vol. 6, No. 5 · pp. 3409-3419

Keywords: FHIT, replication stress, DNA double strand breaks, APOBEC deaminase, mutations

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia Research Paper

Houda Alachkar, Martin B.G. Mutonga, Klaus H. Metzeler, Noreen Fulton, Gregory Malnassy, Tobias Herold, Karsten Spiekermann, Stefan K. Bohlander, Wolfgang Hiddemann, Yo Matsuo, Wendy Stock, Yusuke Nakamura

Published Oct 28, 2014 · Vol. 5, No. 23 · pp. 12371-12382

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Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells Research Paper

Î±-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma Research Paper

Î²III-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer Research Paper

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma Research Paper

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells Research Paper

PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies Clinical Research Papers

Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models Research Paper

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA Research Paper

An HSV-2 based oncolytic virus can function as an attractant to guide migration of adoptively transferred T cells to tumor sites Research Paper

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer Priority Research Paper

The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma Research Paper

Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57 Research Paper

LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myeloma-bone disease Research Paper

Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkinâ€™s lymphomas Research Paper

IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival Clinical Research Papers

PD-L1 is highly expressed in Enzalutamide resistant prostate cancer Research Paper

Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue Priority Research Paper

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis Research Paper

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells Research Paper

Î±-Radioimmunotherapy with 213Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma Research Paper

Î²III-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer Research Paper

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma Research Paper

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells Research Paper

PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies Clinical Research Papers

Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models Research Paper

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA Research Paper

An HSV-2 based oncolytic virus can function as an attractant to guide migration of adoptively transferred T cells to tumor sites Research Paper

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer Priority Research Paper

The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma Research Paper

Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57 Research Paper

LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myeloma-bone disease Research Paper

Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkinâ€™s lymphomas Research Paper

IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival Clinical Research Papers

PD-L1 is highly expressed in Enzalutamide resistant prostate cancer Research Paper

Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue Priority Research Paper

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis Research Paper

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia Research Paper

Î±-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma Research Paper