The Oncosearch | Oncotarget

Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3KÎ´ or PKCÎ² signaling pathways Research Paper

Irene Amigo-JimÃ©nez, Elvira BailÃ³n, NoemÃ Aguilera-Montilla, MarÃa JosÃ© Terol, JosÃ© A. GarcÃa-Marco, Angeles GarcÃa-Pardo

Published Nov 2, 2015 · Vol. 6, No. 42 · pp. 44832-44848

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer Research Paper

Thomas A. Mace, Reena Shakya, Omar Elnaggar, Kristin Wilson, Hannah M. Komar, Jennifer Yang, Jason R. Pitarresi, Gregory S. Young, Michael C. Ostrowski, Thomas Ludwig, Tanios Bekaii-Saab, Mark Bloomston, Gregory B. Lesinski

Published Oct 31, 2015 · Vol. 6, No. 42 · pp. 44509-44522

Tumor growth suppression by inhibiting both autophagy and STAT3 signaling in HNSCC Research Paper

Teng-Fei Fan, Lin-Lin Bu, Wei-Ming Wang, Si-Rui Ma, Jian-Feng Liu, Wei-Wei Deng, Liang Mao, Guang-Tao Yu, Cong-Fa Huang, Bing Liu, Wen-Feng Zhang, Zhi-Jun Sun

Published Oct 30, 2015 · Vol. 6, No. 41 · pp. 43581-43593

Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines Research Paper

Liangkun You, Jiawei Shou, Danchen Deng, Liming Jiang, Zhao Jing, Junlin Yao, Hongsen Li, Jiansheng Xie, Zhanggui Wang, Qin Pan, Hongming Pan, Wendong Huang, Weidong Han

Published Oct 26, 2015 · Vol. 6, No. 37 · pp. 40268-40282

Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways Research Paper

David W. Greening, Sze Ting Lee, Hong Ji, Richard J. Simpson, Angela Rigopoulos, Carmel Murone, Catherine Fang, Sylvia Gong, Graeme Oâ€™Keefe, Andrew M. Scott

Published Oct 26, 2015 · Vol. 6, No. 35 · pp. 38166-38180

Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer Research Paper

Min Soo Kim, Won Sung Lee, Joon Jeong, Seong-Jin Kim, Wook Jin

Published Oct 20, 2015 · Vol. 6, No. 37 · pp. 40158-40171

Decreased severity of collagen antibody and lipopolysaccharide-induced arthritis in human IL-32Î² overexpressed transgenic mice Research Paper

Mi Hee Park, Do-Young Yoon, Jung Ok Ban, Dae Hwan Kim, Dong Hun Lee, Sukgil Song, Youngsoo Kim, Sang-Bae Han, Hee Pom Lee, Jin Tae Hong

Published Oct 19, 2015 · Vol. 6, No. 36 · pp. 38566-38577

Stromal cells promote anti-estrogen resistance of breast cancer cells through an insulin-like growth factor binding protein 5 (IGFBP5)/B-cell leukemia/lymphoma 3 (Bcl-3) axis Research Paper

Benjamin Leyh, Angela Dittmer, Theresia Lange, John W. M. Martens, JÃ¼rgen Dittmer

Published Oct 19, 2015 · Vol. 6, No. 36 · pp. 39307-39328

Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo Research Paper

Deyong Jia, Yuan Tan, Huijuan Liu, Sarah Ooi, Li Li, Kathryn Wright, Steffany Bennett, Christina L. Addison, Lisheng Wang

Published Oct 17, 2015 · Vol. 7, No. 1 · pp. 771-785

Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth Research Paper

Surendra K. Shukla, Aneesha Dasgupta, Kamiya Mehla, Venugopal Gunda, Enza Vernucci, Joshua Souchek, Gennifer Goode, Ryan King, Anusha Mishra, Ibha Rai, Sangeetha Nagarajan, Nina V. Chaika, Fang Yu, Pankaj K. Singh

Published Oct 16, 2015 · Vol. 6, No. 38 · pp. 41146-41161

Evaluation of pentacyclic triterpenes found in Perilla frutescens for inhibition of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate Research Paper

Jiyoon Cho, Lisa Tremmel, Okkyung Rho, Andrew M. Camelio, Dionicio Siegel, Thomas J. Slaga, John DiGiovanni

Published Oct 15, 2015 · Vol. 6, No. 36 · pp. 39292-39306

MDP, a database linking drug response data to genomic information, identifies dasatinib and statins as a combinatorial strategy to inhibit YAP/TAZ in cancer cells Research Paper

Cristian Taccioli, Giovanni Sorrentino, Alessandro Zannini, Jimmy Caroli, Domenico Beneventano, Laura Anderlucci, Marco Lolli, Silvio Bicciato, Giannino Del Sal

Published Oct 15, 2015 · Vol. 6, No. 36 · pp. 38854-38865

(E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice Research Paper

Jie Zheng, Mi Hee Park, Dong Ju Son, Min Gi Choi, Jeong Soon Choi, Kyung Tak Nam, Hae Deun Kim, Kevin Rodriguez, Benjamin Gann, Young Wan Ham, Sang Bae Han, Jin Tae Hong

Published Oct 14, 2015 · Vol. 6, No. 39 · pp. 41929-41943

Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells Research Paper

Yuan Qin, Qiang Zhang, Shan Lee, Wei-long Zhong, Yan-rong Liu, Hui-juan Liu, Dong Zhao, Shuang Chen, Ting Xiao, Jing Meng, Xue-shuang Jing, Jing Wang, Bo Sun, Ting-ting Dai, Cheng Yang, Tao Sun, Hong-gang Zhou

Published Oct 14, 2015 · Vol. 6, No. 38 · pp. 40667-40679

Synergistic antitumor efficacy against the EGFRvIII+HER2+ breast cancers by combining trastuzumab with anti-EGFRvIII antibody CH12 Research Paper

Wen Xu, Yanyu Bi, Jiqin Zhang, Juan Kong, Hua Jiang, Mi Tian, Kesang Li, Biao Wang, Cheng Chen, Fei Song, Xiaorong Pan, Bizhi Shi, Xianming Kong, Jianren Gu, Xiumei Cai, Zonghai Li

Published Oct 14, 2015 · Vol. 6, No. 36 · pp. 38840-38853

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells Research Paper

Donatella Malanga, Carmela De Marco, Ilaria Guerriero, Fabiana Colelli, Nicola Rinaldo, Marianna Scrima, Teresa Mirante, Claudia De Vitis, Pietro Zoppoli, Michele Ceccarelli, Miriam Riccardi, Maria Ravo, Alessandro Weisz, Antonella Federico, Renato Franco, Gaetano Rocco, Rita Mancini, Antonia Rizzuto, Elio Gulletta, Gennaro Ciliberto, Giuseppe Viglietto

Published Oct 13, 2015 · Vol. 6, No. 40 · pp. 42667-42686

Mechanisms linking obesity to altered metabolism in mice colon carcinogenesis Research Paper

Lili Nimri, Janan Saadi, Irena Peri, Einav Yehuda-Shnaidman, Betty Schwartz

Published Oct 12, 2015 · Vol. 6, No. 35 · pp. 38195-38209

MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients Research Paper

Leticia De Mattos-Arruda, Giulia Bottai, Paolo G. Nuciforo, Luca Di Tommaso, Elisa Giovannetti, Vicente Peg, Agnese Losurdo, JosÃ© PÃ©rez-Garcia, Giovanna Masci, Fabio Corsi, Javier CortÃ©s, Joan Seoane, George A. Calin, Libero Santarpia

Published Oct 7, 2015 · Vol. 6, No. 35 · pp. 37269-37280

Stathmin drives virus-induced metastasis Editorial

Adrian Whitehouse, Andrew Macdonald

Published Oct 4, 2015 · Vol. 6, No. 32 · pp. 32289-32290

Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide Research Paper

Jia Kang, Stephen Jun Fei Chong, Vignette Zi Qi Ooi, Shireen Vali, Ansu Kumar, Shweta Kapoor, Taher Abbasi, Jayshree L. Hirpara, Thomas Loh, Boon Cher Goh, Shazib Pervaiz

Published Sep 27, 2015 · Vol. 6, No. 33 · pp. 34191-34205

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Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3KÎ´ or PKCÎ² signaling pathways Research Paper

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer Research Paper

Tumor growth suppression by inhibiting both autophagy and STAT3 signaling in HNSCC Research Paper

Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines Research Paper

Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways Research Paper

Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer Research Paper

Decreased severity of collagen antibody and lipopolysaccharide-induced arthritis in human IL-32Î² overexpressed transgenic mice Research Paper

Stromal cells promote anti-estrogen resistance of breast cancer cells through an insulin-like growth factor binding protein 5 (IGFBP5)/B-cell leukemia/lymphoma 3 (Bcl-3) axis Research Paper

Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo Research Paper

Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth Research Paper

Evaluation of pentacyclic triterpenes found in Perilla frutescens for inhibition of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate Research Paper

MDP, a database linking drug response data to genomic information, identifies dasatinib and statins as a combinatorial strategy to inhibit YAP/TAZ in cancer cells Research Paper

(E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice Research Paper

Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells Research Paper

Synergistic antitumor efficacy against the EGFRvIII+HER2+ breast cancers by combining trastuzumab with anti-EGFRvIII antibody CH12 Research Paper

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells Research Paper

Mechanisms linking obesity to altered metabolism in mice colon carcinogenesis Research Paper

MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients Research Paper

Stathmin drives virus-induced metastasis Editorial

Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3KÎ´ or PKCÎ² signaling pathways Research Paper

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer Research Paper

Tumor growth suppression by inhibiting both autophagy and STAT3 signaling in HNSCC Research Paper

Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines Research Paper

Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways Research Paper

Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer Research Paper

Decreased severity of collagen antibody and lipopolysaccharide-induced arthritis in human IL-32Î² overexpressed transgenic mice Research Paper

Stromal cells promote anti-estrogen resistance of breast cancer cells through an insulin-like growth factor binding protein 5 (IGFBP5)/B-cell leukemia/lymphoma 3 (Bcl-3) axis Research Paper

Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo Research Paper

Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth Research Paper

Evaluation of pentacyclic triterpenes found in Perilla frutescens for inhibition of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate Research Paper

MDP, a database linking drug response data to genomic information, identifies dasatinib and statins as a combinatorial strategy to inhibit YAP/TAZ in cancer cells Research Paper

(E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice Research Paper

Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells Research Paper

Synergistic antitumor efficacy against the EGFRvIII+HER2+ breast cancers by combining trastuzumab with anti-EGFRvIII antibody CH12 Research Paper

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells Research Paper

Mechanisms linking obesity to altered metabolism in mice colon carcinogenesis Research Paper

MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients Research Paper

Stathmin drives virus-induced metastasis Editorial

Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide Research Paper