The Oncosearch | Oncotarget

Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed Research Paper

Li-Jin Hsu, Qunying Hong, Shur-Tzu Chen, Hsiang-Lin Kuo, Lori Schultz, John Heath, Sing-Ru Lin, Ming-Hui Lee, Dong-Zhang Li, Zih-Ling Li, Hui-Ching Cheng, Gerard Armand, Nan-Shan Chang

Published Nov 10, 2016 · Vol. 8, No. 12 · pp. 19137-19155

Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells Priority Research Paper

Lindsay C. Spender, G. John Ferguson, Sijia Liu, Chao Cui, Maria Romina Girotti, Gary Sibbet, Ellen B. Higgs, Morven K. Shuttleworth, Tom Hamilton, Paul Lorigan, Michael Weller, David F. Vincent, Owen J. Sansom, Margaret Frame, Peter ten Dijke, Richard Marais, Gareth J. Inman

Published Nov 9, 2016 · Vol. 7, No. 50 · pp. 81995-82012

Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8⁺ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors Research Paper

Ameet K. Mishra, Tanya Kadoishi, Xiaoguang Wang, Emily Driver, Zhangguo Chen, Xiao-Jing Wang, Jing H. Wang

Published Nov 9, 2016 · Vol. 7, No. 49 · pp. 81341-81356

EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells Research Paper

Jinkyoung Kim, Jienan Kong, Hyeyoon Chang, Hayeon Kim, Aeree Kim

Published Nov 4, 2016 · Vol. 7, No. 51 · pp. 85021-85032

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients Research Paper

Evert van den Broek, Oscar Krijgsman, Daoud Sie, Marianne Tijssen, Sandra Mongera, Mark A. van de Wiel, Eric J. Th. Belt, Sjoerd H. den Uil, Herman Bril, Hein B.A.C. Stockmann, Bauke Ylstra, Beatriz Carvalho, Gerrit A. Meijer, Remond J.A. Fijneman

Published Oct 6, 2016 · Vol. 7, No. 45 · pp. 73876-73887

NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells Research Paper

Ki-Hyung Kim, Seong-Hwan Park, Kee Hun Do, Juil Kim, Kyung Un Choi, Yuseok Moon

Published Sep 30, 2016 · Vol. 7, No. 44 · pp. 72148-72166

Genomic characterization of liver metastases from colorectal cancer patients Research Paper

JosÃ© MarÃa SayaguÃ©s, LuÃs Antonio Corchete, MarÃa Laura GutiÃ©rrez, Maria Eugenia Sarasquete, MarÃa del Mar Abad, Oscar Bengoechea, Encarna FermiÃ±Ã¡n, MarÃa Fernanda Anduaga, Sofia del Carmen, Manuel Iglesias, Carmen Esteban, MarÃa Angoso, Jose Antonio Alcazar, Jacinto GarcÃa, Alberto Orfao, LuÃs MuÃ±oz-Bellvis

Published Sep 20, 2016 · Vol. 7, No. 45 · pp. 72908-72922

SMAD4 loss enables EGF, TGFÎ²1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells Research Paper

Stefania Moz, Daniela Basso, Dania Bozzato, Paola Galozzi, Filippo Navaglia, Ola H. Negm, Giorgio Arrigoni, Carlo-Federico Zambon, Andrea Padoan, Paddy Tighe, Ian Todd, Cinzia Franchin, Sergio Pedrazzoli, Leonardo Punzi, Mario Plebani

Published Sep 16, 2016 · Vol. 7, No. 43 · pp. 69927-69944

TGF-Î²1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis Research Paper

Xinru Zhou, Yong Mao, Jianjie Zhu, Fanyi Meng, Qi Chen, Lihua Tao, Rui Li, Fengqing Fu, Cuiping Liu, Yuanjia Hu, Weipeng Wang, Hongjian Zhang, Dong Hua, Weichang Chen, Xueguang Zhang

Published Sep 10, 2016 · Vol. 7, No. 41 · pp. 67196-67211

Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-Î² pathway Research Paper

Loreto Boix, Juan Manuel LÃ³pez-Oliva, Ana Carolina Rhodes, Jordi Bruix

Published Sep 7, 2016 · Vol. 7, No. 44 · pp. 71309-71329

TGF-Î²1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways Research Paper

Siyuan Xiong, Jung-Chien Cheng, Christian Klausen, Jianfang Zhao, Peter C.K. Leung

Published Aug 16, 2016 · Vol. 7, No. 38 · pp. 61262-61272

Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4 Research Paper

Lei Yang, Shusheng Hu, Jinjing Tan, Xiaojing Zhang, Wen Yuan, Qian Wang, Lingling Xu, Jian Liu, Zheng Liu, Yanjun Jia, Xiaoxi Huang

Published Aug 9, 2016 · Vol. 7, No. 38 · pp. 61562-61574

MicroRNA-93-5p may participate in the formation of morphine tolerance in bone cancer pain mouse model by targeting Smad5 Research Paper

Wen-Feng Xiao, Yu-Sheng Li, Wei Lou, Ting Cai, Shun Zhang, Xiao-Ying Hu, Xing-Wang Zhang, Wei Luo

Published Jul 11, 2016 · Vol. 7, No. 32 · pp. 52104-52114

Epstein-Barr virus BARF1-induced NFÎºB/miR-146a/SMAD4 alterations in stomach cancer cells Research Paper

Dong Ha Kim, Mee Soo Chang, Chan Jin Yoon, Jaap M. Middeldorp, Olivia M. Martinez, Sun-ju Byeon, Sun Young Rha, Sung Han Kim, Yang Soo Kim, Jun Hee Woo

Published Jul 9, 2016 · Vol. 7, No. 50 · pp. 82213-82227

MicroRNA-205 targets SMAD4 in non-small cell lung cancer and promotes lung cancer cell growth in vitro and in vivo Research Paper

Yuanyuan Zeng, Jianjie Zhu, Dan Shen, Hualong Qin, Zhe Lei, Wei Li, Zeyi Liu, Jian-an Huang

Published Jun 30, 2016 · Vol. 8, No. 19 · pp. 30817-30829

Molecular driver alterations and their clinical relevance in cancer of unknown primary site Research Paper

Harald LÃ¶ffler, Nicole Pfarr, Mark Kriegsmann, Volker Endris, Thomas Hielscher, Philipp Lohneis, Gunnar Folprecht, Albrecht Stenzinger, Manfred Dietel, Wilko Weichert, Alwin KrÃ¤mer

Published Jun 14, 2016 · Vol. 7, No. 28 · pp. 44322-44329

MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4 Research Paper

Dantong Cheng, Senlin Zhao, Huamei Tang, Dongyuan Zhang, Hongcheng Sun, Fudong Yu, Weiliang Jiang, Ben Yue, Jingtao Wang, Meng Zhang, Yang Yu, Xisheng Liu, Xiaofeng Sun, Zongguang Zhou, Xuebin Qin, Xin Zhang, Dongwang Yan, Yugang Wen, Zhihai Peng

Published Jun 7, 2016 · Vol. 7, No. 29 · pp. 45199-45213

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen Research Paper

Maurice P.H.M. Jansen, John W.M. Martens, Jean C.A. Helmijr, Corine M. Beaufort, Ronald van Marion, Niels M.G. Krol, Kim Monkhorst, Anita M.A.C. Trapman- Jansen, Marion E. Meijer-van Gelder, Marjolein J.A. Weerts, Diana E. Ramirez- Ardila, Hendrikus Jan Dubbink, John A. Foekens, Stefan Sleijfer, Els M.J.J. Berns

Published May 30, 2016 · Vol. 7, No. 28 · pp. 43412-43418

The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons Research Paper

Riccardo Vezzali, Stefan Christopher Weise, Nicole Hellbach, Venissa Machado, Stefanie Heidrich, Tanja Vogel

Published May 21, 2016 · Vol. 7, No. 25 · pp. 37436-37455

Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling Research Paper

Siyuan Xiong, Christian Klausen, Jung-Chien Cheng, Peter C.K. Leung

Published May 19, 2016 · Vol. 7, No. 26 · pp. 40060-40072

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Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed Research Paper

Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells Priority Research Paper

Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8⁺ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors Research Paper

EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells Research Paper

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients Research Paper

NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells Research Paper

Genomic characterization of liver metastases from colorectal cancer patients Research Paper

SMAD4 loss enables EGF, TGFÎ²1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells Research Paper

TGF-Î²1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis Research Paper

Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-Î² pathway Research Paper

TGF-Î²1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways Research Paper

Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4 Research Paper

MicroRNA-93-5p may participate in the formation of morphine tolerance in bone cancer pain mouse model by targeting Smad5 Research Paper

Epstein-Barr virus BARF1-induced NFÎºB/miR-146a/SMAD4 alterations in stomach cancer cells Research Paper

MicroRNA-205 targets SMAD4 in non-small cell lung cancer and promotes lung cancer cell growth in vitro and in vivo Research Paper

Molecular driver alterations and their clinical relevance in cancer of unknown primary site Research Paper

MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4 Research Paper

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen Research Paper

The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons Research Paper

Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed Research Paper

Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells Priority Research Paper

Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8+ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors Research Paper

EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells Research Paper

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients Research Paper

NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells Research Paper

Genomic characterization of liver metastases from colorectal cancer patients Research Paper

SMAD4 loss enables EGF, TGFÎ²1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells Research Paper

TGF-Î²1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis Research Paper

Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-Î² pathway Research Paper

TGF-Î²1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways Research Paper

Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4 Research Paper

MicroRNA-93-5p may participate in the formation of morphine tolerance in bone cancer pain mouse model by targeting Smad5 Research Paper

Epstein-Barr virus BARF1-induced NFÎºB/miR-146a/SMAD4 alterations in stomach cancer cells Research Paper

MicroRNA-205 targets SMAD4 in non-small cell lung cancer and promotes lung cancer cell growth in vitro and in vivo Research Paper

Molecular driver alterations and their clinical relevance in cancer of unknown primary site Research Paper

MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4 Research Paper

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen Research Paper

The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons Research Paper

Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling Research Paper

Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8⁺ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors Research Paper