The Oncosearch | Oncotarget

Role of TGF-Î² signaling in uterine carcinosarcoma Research Paper

Shailendra Kumar Dhar Dwivedi, Scott D. McMeekin, Katrina Slaughter, Resham Bhattacharya

Published Mar 30, 2015 · Vol. 6, No. 16 · pp. 14646-14655

Leucine-rich Î±-2-glycoprotein promotes TGFÎ²1-mediated growth suppression in the Lewis lung carcinoma cell lines Research Paper

Norihiko Takemoto, Satoshi Serada, Minoru Fujimoto, Honda Hiromi, Tomoharu Ohkawara, Tsuyoshi Takahashi, Shintaro Nomura, Hidenori Inohara, Tetsuji Naka

Published Mar 12, 2015 · Vol. 6, No. 13 · pp. 11009-11022

Transforming growth factor-Î² pathway activity in glioblastoma Research Paper

Karl Frei, Dorothee Gramatzki, Isabel Tritschler, Judith Johanna Schroeder, Larisa Espinoza, Elisabeth Jane Rushing, Michael Weller

Published Feb 28, 2015 · Vol. 6, No. 8 · pp. 5963-5977

Molecular landscape of pancreatic cancer: implications for current clinical trials Review

Gregory M. Heestand, Razelle Kurzrock

Published Feb 24, 2015 · Vol. 6, No. 7 · pp. 4553-4561

SKI2162, an inhibitor of the TGF-Î² type I receptor (ALK5), inhibits radiation-induced fibrosis in mice Research Paper

Jin-hong Park, Seung-Hee Ryu, Eun Kyung Choi, Seung Do Anh, Euisun Park, Kyung-Chul Choi, Sang-wook Lee

Published Feb 17, 2015 · Vol. 6, No. 6 · pp. 4171-4179

Keywords: Radiation, Fibrosis, TGF-Î²1, ALK5, SKI2162

Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer Research Paper

Matti Annala, Kati Kivinummi, Joonas Tuominen, Serdar Karakurt, Kirsi Granberg, Leena Latonen, Antti YlipÃ¤Ã¤, Liisa SjÃ¶blom, Pekka Ruusuvuori, Outi SaramÃ¤ki, Kirsi M. Kaukoniemi, Olli Yli-Harja, Robert L. Vessella, Teuvo L.J. Tammela, Wei Zhang, Tapio Visakorpi, Matti Nykter

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6235-6250

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

Qiongshu Li, Guomu Liu, Hongyan Yuan, Juan Wang, Yingying Guo, Tanxiu Chen, Ruiping Zhai, Dan Shao, Weihua Ni, Guixiang Tai

Published Jan 20, 2015 · Vol. 6, No. 6 · pp. 4253-4265

Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway Research Paper

Wanxing Duan, Rong Li, Jiguang Ma, Jianjun Lei, Qinhong Xu, Zhengdong Jiang, Ligang Nan, Xuqi Li, Zheng Wang, Xiongwei Huo, Liang Han, Zheng Wu, Erxi Wu, Qingyong Ma

Published Dec 1, 2014 · Vol. 6, No. 3 · pp. 1490-1506

The head and neck cancer cell oncogenome: A platform for the development of precision molecular therapies Priority Research Paper

Daniel Martin, Martin C. Abba, Alfredo A. Molinolo, Lynn Vitale-Cross, Zhiyong Wang, Moraima Zaida, Naomi C. Delic, Yardena Samuels, Guy J. Lyons, J. Silvio Gutkind

Published Nov 4, 2014 · Vol. 5, No. 19 · pp. 8906-8923

microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway Research Paper

Jia Wang, Eagle S.H . Chu, Hai-Yong Chen, Kwan Man, Minnie Y.Y. Go, Xiao Ru Huang, Hui Yao Lan, Joseph J.Y. Sung, Jun Yu

Published Oct 22, 2014 · Vol. 6, No. 9 · pp. 7325-7338

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia Research Paper

Shachar Raz, Michal Stark, Yehuda G. Assaraf

Published Aug 27, 2014 · Vol. 5, No. 19 · pp. 9183-9198

Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFÎ² receptor degradation Research Paper

Hsien-Yeh Hsu, Tung-Yi Lin, Yu-Chung Wu, Shu-Ming Tsao, Pai-An Hwang, Yu-Wei Shih, Jason Hsu

Published Aug 6, 2014 · Vol. 5, No. 17 · pp. 7870-7885

Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-Î²/Smad signaling pathway Research Paper

Jiang Geng, Jie Fan, Qi Ouyang, Xiaopeng Zhang, Xiaolong Zhang, Juan Yu, Zude Xu, Qianyu Li, Xudong Yao, Xiuping Liu, Junhua Zheng

Published Jul 1, 2014 · Vol. 5, No. 14 · pp. 5700-5711

Snail regulates Nanog status during the epithelialâ€“mesenchymal transition via the Smad1/Akt/GSK3Î² signaling pathway in non-small-cell lung cancer Research Paper

Chen-Wei Liu, Ching-Hao Li, Yi-Jen Peng, Yu-Wen Cheng, Huei-Wen Chen, Po-Lin Liao, Jaw-Jou Kang, Mao-Hsiung Yen

Published May 26, 2014 · Vol. 5, No. 11 · pp. 3880-3894

Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups Research Paper

Michele Simbolo, Matteo Fassan, Andrea Ruzzenente, Andrea Mafficini, Laura D. Wood, Vincenzo Corbo, Davide Melisi, Giuseppe Malleo, Caterina Vicentini, Giorgio Malpeli, Davide Antonello, Nicola Sperandio, Paola Capelli, Anna Tomezzoli, Calogero Iacono, Rita T. Lawlor, Claudio Bassi, Ralph H. Hruban, Alfredo Guglielmi, Giampaolo Tortora, Filippo de Braud, Aldo Scarpa

Published May 1, 2014 · Vol. 5, No. 9 · pp. 2839-2852

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

Hendrik Ungefroren, Susanne Sebens, Klaudia Giehl, Ole Helm, Stephanie Groth, Fred Faendrich, Christoph Roecken, Bence Sipos, Hendrik Lehnert, Frank Gieseler

Published Dec 23, 2013 · Vol. 5, No. 1 · pp. 277-290

Keywords: Rac1b, Rac1, Smad, TGF-beta1, pancreatic ductal adenocarcinoma, cell migration

Perspectives of TGF-Î² inhibition in pancreatic and hepatocellular carcinomas Review

Cindy Neuzillet, Armand de Gramont, AnnemilaÃ¯ Tijeras-Raballand, Louis de Mestier, JÃ©rÃ´me Cros, Sandrine Faivre, Eric Raymond

Published Dec 18, 2013 · Vol. 5, No. 1 · pp. 78-94

Keywords: SMAD, stellate cells, extracellular matrix, EMT, TGF-Î² inhibitors

A novel co-operative mechanism linking TGFÎ² and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells Brief Reports

Andrew Chantry, Paul G Smith, Hideo Tanaka

Published May 24, 2012 · Vol. 3, No. 5 · pp. 518-524

Keywords: Transforming growth factor-Î², Smads, ubiquitin, c-cbl, Lyn, leukaemia

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Role of TGF-Î² signaling in uterine carcinosarcoma Research Paper

Leucine-rich Î±-2-glycoprotein promotes TGFÎ²1-mediated growth suppression in the Lewis lung carcinoma cell lines Research Paper

Transforming growth factor-Î² pathway activity in glioblastoma Research Paper

Molecular landscape of pancreatic cancer: implications for current clinical trials Review

SKI2162, an inhibitor of the TGF-Î² type I receptor (ALK5), inhibits radiation-induced fibrosis in mice Research Paper

Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway Research Paper

The head and neck cancer cell oncogenome: A platform for the development of precision molecular therapies Priority Research Paper

microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway Research Paper

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia Research Paper

Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFÎ² receptor degradation Research Paper

Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-Î²/Smad signaling pathway Research Paper

Snail regulates Nanog status during the epithelialâ€“mesenchymal transition via the Smad1/Akt/GSK3Î² signaling pathway in non-small-cell lung cancer Research Paper

Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups Research Paper

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

Perspectives of TGF-Î² inhibition in pancreatic and hepatocellular carcinomas Review

A novel co-operative mechanism linking TGFÎ² and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells Brief Reports

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Role of TGF-Î² signaling in uterine carcinosarcoma Research Paper

Leucine-rich Î±-2-glycoprotein promotes TGFÎ²1-mediated growth suppression in the Lewis lung carcinoma cell lines Research Paper

Transforming growth factor-Î² pathway activity in glioblastoma Research Paper

Molecular landscape of pancreatic cancer: implications for current clinical trials Review

SKI2162, an inhibitor of the TGF-Î² type I receptor (ALK5), inhibits radiation-induced fibrosis in mice Research Paper

Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway Research Paper

The head and neck cancer cell oncogenome: A platform for the development of precision molecular therapies Priority Research Paper

microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway Research Paper

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia Research Paper

Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFÎ² receptor degradation Research Paper

Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-Î²/Smad signaling pathway Research Paper

Snail regulates Nanog status during the epithelialâ€“mesenchymal transition via the Smad1/Akt/GSK3Î² signaling pathway in non-small-cell lung cancer Research Paper

Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups Research Paper

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

Perspectives of TGF-Î² inhibition in pancreatic and hepatocellular carcinomas Review

A novel co-operative mechanism linking TGFÎ² and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells Brief Reports

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper