The Oncosearch | Oncotarget

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

Lanlan Zhou, Kelsey Huntington, Shengliang Zhang, Lindsey Carlsen, Eui-Young So, Cassandra Parker, Ilyas Sahin, Howard Safran, Suchitra Kamle, Chang-Min Lee, Chun Geun Lee, Jack A. Elias, Kerry S. Campbell, Mandar T. Naik, Walter J. Atwood, Emile Youssef, Jonathan A. Pachter, Arunasalam Navaraj, Attila A. Seyhan, Olin Liang, Wafik S. El-Deiry

Published Oct 28, 2020

Keywords: ACE2, TMPRSS2, SARS-CoV-2, COVID-19, pseudovirus

The impact of the RASSF1C and PIWIL1 on DNA methylation: the identification of GMIP as a tumor suppressor Research Paper

Yousef G. Amaar, Mark E. Reeves

Published Oct 26, 2020 · Vol. 11, No. 45 · pp. 4082-4092

Keywords: lung cancer, RASSF1C, PIWIL1, DNA metylation,

Polymerized human hemoglobin increases the effectiveness of cisplatin-based chemotherapy in non-small cell lung cancer Research Paper

Alfredo Lucas, Donald A. Belcher, Carlos Munoz, Alexander T. Williams, Andre F. Palmer, Pedro Cabrales

Published Oct 7, 2020 · Vol. 11, No. 42 · pp. 3770-3781

Keywords: chemotherapy, cisplatin, polymerized hemoglobin, non-small cell lung cancer, hypoxia

Correction: Clinical significance and effect of AEG-1 on the proliferation, invasion, and migration of NSCLC: a study based on immunohistochemistry, TCGA, bioinformatics, in vitro and in vivo verification Correction

Yu Zhang, Zu-Yun Li, Xin-Xi Hou, Xiao Wang, Yi-Huan Luo, Yan-Ping Ying, Gang Chen

Published Sep 23, 2020

Repression of YAP by NCTD disrupts NSCLC progression Correction

Jiwei Guo, Yan Wu, Lijuan Yang, Jing Du, Kaikai Gong, Weiwei Chen, Juanjuan Dai, XueLin Li, Sichuan Xi

Published Sep 1, 2020

Altered lung tissue lipidomic profile in caspase-4 positive non-small cell lung cancer (NSCLC) patients Research Paper

Michela Terlizzi, Antonio Molino, Chiara Colarusso, Pasquale Somma, Ilaria De Rosa, Jacopo Troisi, Giovanni Scala, Rosario Salvi, Aldo Pinto, Rosalinda Sorrentino

Published Aug 19, 2020 · Vol. 11, No. 38 · pp. 3515-3525

Keywords: NSCLC, metabolomic, lipidomic, metabotype, caspase-4

Survival after resection of brain metastases with white light microscopy versus fluorescence-guidance: A matched cohort analysis of the Metastasys study data Research Paper

Abdelhalim Hussein, Veit Rohde, Christina Wolfert, Silvia Hernandez-Duran, Ingo Fiss, Annalen Bleckmann, Alonso Barrantes Freer, Dorothee Mielke, Bawarjan Schatlo

Published Jul 20, 2020 · Vol. 11, No. 32 · pp. 3026-3034

Keywords: brain tumor, brain metastasis, fluorescence-guided surgery, 5-ALA

A multicenter, single-arm, basket design, phase II study of NC-6004 plus gemcitabine in patients with advanced unresectable lung, biliary tract, or bladder cancer Research Paper

Simona Ruxandra Volovat, Tudor-Eliade Ciuleanu, Piotr Koralewski, Juneko E. Grilley Olson, Adina Croitoru, Krassimir Koynov, Stefano Stabile, Giulio Cerea, Atsushi Osada, Iulian Bobe, Constantin Volovat

Published Jul 15, 2020 · Vol. 11, No. 33 · pp. 3105-3117

Keywords: cisplatin, NC-6004, non-small cell lung cancer, biliary tract cancer, bladder cancer

Triptolide-induced apoptosis in non-small cell lung cancer via a novel miR204-5p/Caveolin-1/Akt-mediated pathway Research Paper

Brian J. Philips, Ajay Kumar, Sarah Burki, John P. Ryan, Kentaro Noda, Jonathan D’Cunha

Published Jun 30, 2020 · Vol. 11, No. 28 · pp. 2793-2806

Keywords: triptolide, lung cancer, caveolin-1, miR204-5p, apoptosis

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Abhay Kumar Singh, Vaishali Kapoor, Dinesh Thotala, Dennis E. Hallahan

Published Jun 22, 2020 · Vol. 11, No. 27 · pp. 2647-2659

Keywords: TAF15, radiation inducible, lung cancer, antibody

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Nicholas J. Monteleone, Carol S. Lutz

Published May 22, 2020 · Vol. 11, No. 26 · pp. 2464-2483

Keywords: miR-708-5p, miR-708, lung cancer, COX-2, mPGES-1

The role of EGFR mutations in predicting recurrence in early and locally advanced lung adenocarcinoma following definitive therapy Research Paper

Carlos Galvez, Saya Jacob, Brian S. Finkelman, Jeffrey Zhao, Kyle Tegtmeyer, Young Kwang Chae, Nisha Mohindra, Ravi Salgia, Borko Jovanovic, Amir Behdad, Victoria Villaflor

Published May 6, 2020 · Vol. 11, No. 21 · pp. 1953-1960

Keywords: non-small cell lung cancer, lung adenocarcinoma, EGFR, early, recurrence

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells Research Paper

Al Hassan Kyakulaga, Farrukh Aqil, Radha Munagala, Ramesh C. Gupta

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1399-1416

Keywords: non-small cell lung cancer, withaferin A, synergistic, combination index, paclitaxel

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Valentina Masciale, Giulia Grisendi, Federico Banchelli, Roberto D’Amico, Antonino Maiorana, Pamela Sighinolfi, Alessandro Stefani, Uliano Morandi, Massimo Dominici, Beatrice Aramini

Published Apr 16, 2020 · Vol. 11, No. 17 · pp. 1545-1555

Keywords: immunophenotype, cancer stem cells, cancer stem-like cells, non-small cell lung cancer (NSCLC), target therapy

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Matthew H. Taylor, Ajjai S. Alva, Timothy Larson, Sebastian Szpakowski, Das Purkaystha, Alpesh Amin, Linda Karpiak, Sarina A. Piha-Paul

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1235-1243

Keywords: advanced malignancies, basket trial, dovitinib, histology-agnostic, mutation-specific

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Makhan Kumar, Ansie Martin, Snehal Nirgude, Bibha Chaudhary, Sukanta Mondal, Angshuman Sarkar

Published Apr 6, 2020 · Vol. 11, No. 18 · pp. 1603-1617

Keywords: quinacrine, NSCLC, RhoGTPases, apoptosis, cell cycle

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Fiamma Buttitta, Lara Felicioni, Alessia Di Lorito, Alessio Cortellini, Luciana Irtelli, Davide Brocco, Pietro Di Marino, Donatella Traisci, Nicola D’Ostilio, Alessandra Di Paolo, Francesco Malorgio, Pasquale Assalone, Sonia Di Felice, Francesca Fabbri, Giovanni Cianci, Michele De Tursi, Antonio Marchetti

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 982-991

Keywords: epidermal growth factor receptor (EGFR), tyrosine-kinase Inhibitors, circulating tumor-DNA (ct-DNA), massive parallel sequencing (MPS), resistance-inducing mutation

Overall survival in patients with lung adenocarcinoma harboring “niche” mutations: an observational study Research Paper

Beatrice Aramini, Federico Banchelli, Stefania Bettelli, Samantha Manfredini, Roberto D’Amico, Valentina Masciale, Massimo Pinelli, Margherita Moretti, Alessandro Stefani, Federica Bertolini, Massimo Dominici, Uliano Morandi, Antonino Maiorana

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 550-559

Keywords: somatic mutations, non-small cell lung cancer (NSCLC), lung cancer treatment, overall survival, target therapy

TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC Research Paper

Julia Roeper, Markus Falk, Athena Chalaris-Rißmann, Anne C. Lueers, Hayat Ramdani, Katrin Wedeken, Ursula Stropiep, Linda Diehl, Markus Tiemann, Lukas C. Heukamp, Fabian Otto-Sobotka, Frank Griesinger

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 250-264

Keywords: NSCLC, EGFR, TP53 mutation, TKI

Circulating tumor DNA analysis in the era of precision oncology Review

Rabih Said, Nicolas Guibert, Geoffrey R. Oxnard, Apostolia M. Tsimberidou

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 188-211

Keywords: circulating tumor DNA analysis, clinical trials, targeted therapy, genomic profiling

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

The impact of the RASSF1C and PIWIL1 on DNA methylation: the identification of GMIP as a tumor suppressor Research Paper

Polymerized human hemoglobin increases the effectiveness of cisplatin-based chemotherapy in non-small cell lung cancer Research Paper

Correction: Clinical significance and effect of AEG-1 on the proliferation, invasion, and migration of NSCLC: a study based on immunohistochemistry, TCGA, bioinformatics, in vitro and in vivo verification Correction

Repression of YAP by NCTD disrupts NSCLC progression Correction

Altered lung tissue lipidomic profile in caspase-4 positive non-small cell lung cancer (NSCLC) patients Research Paper

Survival after resection of brain metastases with white light microscopy versus fluorescence-guidance: A matched cohort analysis of the Metastasys study data Research Paper

A multicenter, single-arm, basket design, phase II study of NC-6004 plus gemcitabine in patients with advanced unresectable lung, biliary tract, or bladder cancer Research Paper

Triptolide-induced apoptosis in non-small cell lung cancer via a novel miR204-5p/Caveolin-1/Akt-mediated pathway Research Paper

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

The role of EGFR mutations in predicting recurrence in early and locally advanced lung adenocarcinoma following definitive therapy Research Paper

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Overall survival in patients with lung adenocarcinoma harboring “niche” mutations: an observational study Research Paper

TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC Research Paper

Circulating tumor DNA analysis in the era of precision oncology Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

The impact of the RASSF1C and PIWIL1 on DNA methylation: the identification of GMIP as a tumor suppressor Research Paper

Polymerized human hemoglobin increases the effectiveness of cisplatin-based chemotherapy in non-small cell lung cancer Research Paper

Correction: Clinical significance and effect of AEG-1 on the proliferation, invasion, and migration of NSCLC: a study based on immunohistochemistry, TCGA, bioinformatics, in vitro and in vivo verification Correction

Repression of YAP by NCTD disrupts NSCLC progression Correction

Altered lung tissue lipidomic profile in caspase-4 positive non-small cell lung cancer (NSCLC) patients Research Paper

Survival after resection of brain metastases with white light microscopy versus fluorescence-guidance: A matched cohort analysis of the Metastasys study data Research Paper

A multicenter, single-arm, basket design, phase II study of NC-6004 plus gemcitabine in patients with advanced unresectable lung, biliary tract, or bladder cancer Research Paper

Triptolide-induced apoptosis in non-small cell lung cancer via a novel miR204-5p/Caveolin-1/Akt-mediated pathway Research Paper

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

The role of EGFR mutations in predicting recurrence in early and locally advanced lung adenocarcinoma following definitive therapy Research Paper

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDHhigh cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G1/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Overall survival in patients with lung adenocarcinoma harboring “niche” mutations: an observational study Research Paper

TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC Research Paper

Circulating tumor DNA analysis in the era of precision oncology Review

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper