The Oncosearch | Oncotarget

Prevalence of pathogenic germline variants detected by multigene sequencing in unselected Japanese patients with ovarian cancer Research Paper

Akira Hirasawa, Issei Imoto, Takuya Naruto, Tomoko Akahane, Wataru Yamagami, Hiroyuki Nomura, Kiyoshi Masuda, Nobuyuki Susumu, Hitoshi Tsuda, Daisuke Aoki

Published Nov 28, 2017 · Vol. 8, No. 68 · pp. 112258-112267

MBD4 frameshift mutation caused by DNA mismatch repair deficiency enhances cytotoxicity by trifluridine, an active antitumor agent of TAS-102, in colorectal cancer cells Research Paper

Satoshi Suzuki, Moriya Iwaizumi, Hidetaka Yamada, Tomohiro Sugiyama, Yasushi Hamaya, Takahisa Furuta, Shigeru Kanaoka, Haruhiko Sugimura, Hiroaki Miyajima, Satoshi Osawa, John M. Carethers, Ken Sugimoto

Published Nov 15, 2017 · Vol. 9, No. 14 · pp. 11477-11488

Combination of primary tumor location and mismatch repair status guides adjuvant chemotherapy in stage II colon cancer Clinical Research Papers

Lin Yang, Wenzhuo He, Qiong Yang, Pengfei Kong, Qiankun Xie, Chang Jiang, Bei Zhang, Liang Ping Xia

Published Oct 12, 2017 · Vol. 8, No. 58 · pp. 99136-99149

Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia Research Paper

Hassan Ashktorab, Hamed Azimi, Sudhir Varma, Payaam Tavakoli, Michael L. Nickerson, Hassan Brim

Published Oct 7, 2017 · Vol. 8, No. 59 · pp. 99966-99977

Functional network analysis of gene-phenotype connectivity associated with temozolomide Research Paper

Jia Shi, Bo Dong, Peng Zhou, Wei Guan, Ya Peng

Published Sep 12, 2017 · Vol. 8, No. 50 · pp. 87554-87567

Correlating programmed death ligand 1 (PD-L1) expression, mismatch repair deficiency, and outcomes across tumor types: implications for immunotherapy Research Paper

Seung Tae Kim, Samuel J. Klempner, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Kyoung-Mee Kim, Jeeyun Lee

Published Aug 24, 2017 · Vol. 8, No. 44 · pp. 77415-77423

Impact of mismatch-repair deficiency on the colorectal cancer immune microenvironment Research Paper

Yingyi Zhang, Zhao Sun, Xinxin Mao, Huanwen Wu, Fei Luo, Xi Wu, Liangrui Zhou, Jing Qin, Lin Zhao, Chunmei Bai

Published Aug 14, 2017 · Vol. 8, No. 49 · pp. 85526-85536

DNA mismatch repair protein Mlh1 is required for tetravalent chromium intermediate-induced DNA damage Research Paper

Timothy P. Wakeman, Aimin Yang, Naresh S. Dalal, Rebecca J Boohaker, Qinghua Zeng, Qiang Ding, Bo Xu

Published Aug 10, 2017 · Vol. 8, No. 48 · pp. 83975-83985

A novel heterozygous germline deletion in MSH2 gene in a five generation Chinese family with Lynch syndrome Research Paper

Bin Wu, Wuyang Ji, Shengran Liang, Chao Ling, Yan You, Lai Xu, Min-Er Zhong, Yi Xiao, Hui-Zhong Qiu, Jun-Yang Lu, Santasree Banerjee

Published Jul 14, 2017 · Vol. 8, No. 33 · pp. 55194-55203

BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations Priority Research Paper

Safoora Deihimi, Avital Lev, Michael Slifker, Elena Shagisultanova, Qifang Xu, Kyungsuk Jung, Namrata Vijayvergia, Eric A. Ross, Joanne Xiu, Jeffrey Swensen, Zoran Gatalica, Mark Andrake, Roland L. Dunbrack, Wafik S. El-Deiry

Published May 23, 2017 · Vol. 8, No. 25 · pp. 39945-39962

Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair Research Paper

Sohail Jahid, Jian Sun, Ozkan Gelincik, Pedro Blecua, Winfried Edelmann, Raju Kucherlapati, Kathy Zhou, Maria Jasin, Zeynep H. GÃ¼mÃ¼ÅŸ, Steven M. Lipkin

Published May 10, 2017 · Vol. 8, No. 42 · pp. 71574-71586

Local immune response depends on p16^INK4a status of primary tumor in vulvar squamous cell carcinoma Research Paper

Jacek J. Sznurkowski, Anton Å»awrocki, Wojciech Biernat

Published May 3, 2017 · Vol. 8, No. 28 · pp. 46204-46210

Germline mutations in pancreatic cancer and potential new therapeutic options Review

Rille Pihlak, Juan W. Valle, MairÃ©ad G. McNamara

Published Apr 20, 2017 · Vol. 8, No. 42 · pp. 73240-73257

Serrated adenocarcinoma morphology in colorectal mucinous adenocarcinoma is associated with improved patient survival Research Paper

Chung-Ta Lee, Yu-Chuan Huang, Liang-Yi Hung, Nan-Haw Chow, Pei-Fang Su, Chung-Liang Ho, Hung-Wen Tsai, Yi-Lin Chen, Shao-Chieh Lin, Bo-Wen Lin, Peng-Chan Lin, Jenq-Chang Lee

Published Apr 4, 2017 · Vol. 8, No. 21 · pp. 35165-35175

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer Research Paper

Hyo Song Kim, Hanna Lee, Su-Jin Shin, Seung-Hoon Beom, Minkyu Jung, Sujin Bae, Eun Young Lee, Kyu Hyun Park, Yoon Young Choi, Taeil Son, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee, Woong Sub Koom, Joon Seok Lim, Hyun Cheol Chung, Sung Hoon Noh, Sun Young Rha, Hyunki Kim, Soonmyung Paik

Published Mar 21, 2017 · Vol. 8, No. 24 · pp. 38389-38398

Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-Î² Research Paper

Jun-Yu Lu, Peng Jin, Wei Gao, De-Zhi Wang, Jian-Qiu Sheng

Published Mar 18, 2017 · Vol. 8, No. 24 · pp. 38767-38779

The molecular heterogeneity of sporadic colorectal cancer with different tumor sites in Chinese patients Research Paper

Junjie Peng, Dan Huang, Graeme Poston, Xiaoji Ma, Renjie Wang, Weiqi Sheng, Xiaoyan Zhou, Xiaoli Zhu, Sanjun Cai

Published Mar 14, 2017 · Vol. 8, No. 30 · pp. 49076-49083

Limited impact of intratumour heterogeneity on molecular risk assignment in endometrial cancer Research Paper

Manouk van Esterik, Inge C. Van Gool, Cor D. de Kroon, Remi A. Nout, Carien L. Creutzberg, Vincent T.H.B.M. Smit, Tjalling Bosse, Ellen Stelloo

Published Mar 10, 2017 · Vol. 8, No. 15 · pp. 25542-25551

Lynch syndrome-related small intestinal adenocarcinomas Research Paper

Sun-Young Jun, Eui-Jin Lee, Mi-Ju Kim, Sung Min Chun, Young Kyung Bae, Soon Uk Hong, Jene Choi, Joon Mee Kim, Kee-Taek Jang, Jung Yeon Kim, Gwang Il Kim, Soo Jin Jung, Ghilsuk Yoon, Seung-Mo Hong

Published Feb 11, 2017 · Vol. 8, No. 13 · pp. 21483-21500

Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy Research Paper

Natalia M. Leguisamo, Helena C. Gloria, Antonio N. Kalil, Talita V. Martins, Daniel B. Azambuja, Lisiane B. Meira, Jenifer Saffi

Published Jan 31, 2017 · Vol. 8, No. 33 · pp. 54199-54214

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Prevalence of pathogenic germline variants detected by multigene sequencing in unselected Japanese patients with ovarian cancer Research Paper

MBD4 frameshift mutation caused by DNA mismatch repair deficiency enhances cytotoxicity by trifluridine, an active antitumor agent of TAS-102, in colorectal cancer cells Research Paper

Combination of primary tumor location and mismatch repair status guides adjuvant chemotherapy in stage II colon cancer Clinical Research Papers

Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia Research Paper

Functional network analysis of gene-phenotype connectivity associated with temozolomide Research Paper

Correlating programmed death ligand 1 (PD-L1) expression, mismatch repair deficiency, and outcomes across tumor types: implications for immunotherapy Research Paper

Impact of mismatch-repair deficiency on the colorectal cancer immune microenvironment Research Paper

DNA mismatch repair protein Mlh1 is required for tetravalent chromium intermediate-induced DNA damage Research Paper

A novel heterozygous germline deletion in MSH2 gene in a five generation Chinese family with Lynch syndrome Research Paper

BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations Priority Research Paper

Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair Research Paper

Local immune response depends on p16^INK4a status of primary tumor in vulvar squamous cell carcinoma Research Paper

Germline mutations in pancreatic cancer and potential new therapeutic options Review

Serrated adenocarcinoma morphology in colorectal mucinous adenocarcinoma is associated with improved patient survival Research Paper

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer Research Paper

Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-Î² Research Paper

The molecular heterogeneity of sporadic colorectal cancer with different tumor sites in Chinese patients Research Paper

Limited impact of intratumour heterogeneity on molecular risk assignment in endometrial cancer Research Paper

Lynch syndrome-related small intestinal adenocarcinomas Research Paper

Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Prevalence of pathogenic germline variants detected by multigene sequencing in unselected Japanese patients with ovarian cancer Research Paper

MBD4 frameshift mutation caused by DNA mismatch repair deficiency enhances cytotoxicity by trifluridine, an active antitumor agent of TAS-102, in colorectal cancer cells Research Paper

Combination of primary tumor location and mismatch repair status guides adjuvant chemotherapy in stage II colon cancer Clinical Research Papers

Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia Research Paper

Functional network analysis of gene-phenotype connectivity associated with temozolomide Research Paper

Correlating programmed death ligand 1 (PD-L1) expression, mismatch repair deficiency, and outcomes across tumor types: implications for immunotherapy Research Paper

Impact of mismatch-repair deficiency on the colorectal cancer immune microenvironment Research Paper

DNA mismatch repair protein Mlh1 is required for tetravalent chromium intermediate-induced DNA damage Research Paper

A novel heterozygous germline deletion in MSH2 gene in a five generation Chinese family with Lynch syndrome Research Paper

BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations Priority Research Paper

Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair Research Paper

Local immune response depends on p16INK4a status of primary tumor in vulvar squamous cell carcinoma Research Paper

Germline mutations in pancreatic cancer and potential new therapeutic options Review

Serrated adenocarcinoma morphology in colorectal mucinous adenocarcinoma is associated with improved patient survival Research Paper

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer Research Paper

Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-Î² Research Paper

The molecular heterogeneity of sporadic colorectal cancer with different tumor sites in Chinese patients Research Paper

Limited impact of intratumour heterogeneity on molecular risk assignment in endometrial cancer Research Paper

Lynch syndrome-related small intestinal adenocarcinomas Research Paper

Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy Research Paper

Local immune response depends on p16^INK4a status of primary tumor in vulvar squamous cell carcinoma Research Paper