The Oncosearch | Oncotarget

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2 Research Paper

Shinya Ishida, Hiroki Akiyama, Yoshihiro Umezawa, Keigo Okada, Ayako Nogami, Gaku Oshikawa, Toshikage Nagao, Osamu Miura

Published Jun 1, 2018 · Vol. 9, No. 42 · pp. 26834-26851

Hitting two oncogenic machineries in cancer cells: cooperative effects of the multi-kinase inhibitor ponatinib and the BET bromodomain blockers JQ1 or dBET1 on human carcinoma cells Research Paper

Karin Bauer, Daniela Berger, Christoph C. Zielinski, Peter Valent, Thomas W. Grunt

Published May 29, 2018 · Vol. 9, No. 41 · pp. 26491-26506

Translation termination-dependent deadenylation of MYC mRNA in human cells Research Paper

BÃ©atrice Jolles, Affaf Aliouat, VÃ©rÃ¨ne StierlÃ©, Samia Salhi, Olivier Jean-Jean

Published May 25, 2018 · Vol. 9, No. 40 · pp. 26171-26182

Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins Research Paper

Daniela Heilos, Clemens RÃ¶hrl, Christine Pirker, Bernhard Englinger, Dina Baier, Thomas Mohr, Michaela Schwaiger, Shahid Muhammad Iqbal, Sushilla van Schoonhoven, Kristaps Klavins, Tanja Eberhart, Ursula Windberger, Judith Taibon, Sonja Sturm, Hermann Stuppner, Gunda Koellensperger, Rita Dornetshuber-Fleiss, Walter JÃ¤ger, Rosa Lemmens-Gruber, Walter Berger

Published May 22, 2018 · Vol. 9, No. 39 · pp. 25661-25680

B-glucans from Grifola frondosa and Ganoderma lucidum in breast cancer: an example of complementary and integrative medicine Review

Paola Rossi, Raffaele Difrancia, Vincenzo Quagliariello, Elena Savino, Paolo Tralongo, Cinzia Lucia Randazzo, Massimiliano Berretta

Published May 15, 2018 · Vol. 9, No. 37 · pp. 24837-24856

Brief report: RRx-001 is a c-Myc inhibitor that targets cancer stem cells Research Paper

Bryan Oronsky, Tony R. Reid, Arnold Oronsky, Scott Caroen, Corey A. Carter, Pedro Cabrales

Published May 4, 2018 · Vol. 9, No. 34 · pp. 23439-23442

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity Research Paper

Lydia A. Hepburn, Angela McHugh, Kenneth Fernandes, Garry Boag, Charlotte M. Proby, Irene M. Leigh, Mark K. Saville

Published May 1, 2018 · Vol. 9, No. 33 · pp. 23029-23046

Disturbed alternative splicing of FIR (PUF60) directed cyclin E overexpression in esophageal cancers Research Paper

Yukiko Ogura, Tyuji Hoshino, Nobuko Tanaka, Guzhanuer Ailiken, Sohei Kobayashi, Kouichi Kitamura, Bahityar Rahmutulla, Masayuki Kano, Kentarou Murakami, Yasunori Akutsu, Fumio Nomura, Sakae Itoga, Hisahiro Matsubara, Kazuyuki Matsushita

Published May 1, 2018 · Vol. 9, No. 33 · pp. 22929-22944

Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma Research Paper

Takashi Sakaguchi, Hirofumi Yoshino, Satoshi Sugita, Kazutaka Miyamoto, Masaya Yonemori, Yoichi Osako, Makiko Meguro-Horike, Shin-ichi Horike, Masayuki Nakagawa, Hideki Enokida

Published May 1, 2018 · Vol. 9, No. 33 · pp. 23003-23017

FSH receptor binding inhibitor impacts K-Ras and c-Myc of ovarian cancer and signal pathway Research Paper

Suocheng Wei, Xiaoyun Shen, Luju Lai, Haoqin Liang, Yingying Deng, Zhuandi Gong, Tuanjie Che

Published Apr 27, 2018 · Vol. 9, No. 32 · pp. 22498-22508

Comparative oncology DNA sequencing of canine T cell lymphoma via human hotspot panel Research Paper

J. Tyson McDonald, Athena Kritharis, Afshin Beheshti, Monika Pilichowska, Kristine Burgess, Luisel Ricks-Santi, Elizabeth McNiel, Cheryl A. London, Dashnamoorthy Ravi, Andrew M. Evens

Published Apr 27, 2018 · Vol. 9, No. 32 · pp. 22693-22702

Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing Research Paper

Duarte Mendes Oliveira, Teresa Mirante, Chiara Mignogna, Marianna Scrima, Simona Migliozzi, Gaetano Rocco, Renato Franco, Francesco Corcione, Giuseppe Viglietto, Donatella Malanga, Antonia Rizzuto

Published Apr 27, 2018 · Vol. 9, No. 32 · pp. 22749-22768

Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis Research Paper

Kari HÃ¶gstrand, Stephanie Darmanin, TachaZi Plym Forshell, Alf Grandien

Published Apr 20, 2018 · Vol. 9, No. 30 · pp. 21396-21410

MYC gene amplification is a rare event in atypical fibroxanthoma and pleomorphic dermal sarcoma Research Paper

Timo Gaiser, Daniela Hirsch, Azadeh Orouji, Marisa Bach, Peter Kind, Doris Helbig, Alexander Quaas, Jochen Utikal, Alexander Marx, Maria Rita Gaiser

Published Apr 20, 2018 · Vol. 9, No. 30 · pp. 21182-21189

SMAR1 inhibits Wnt/Î²-catenin signaling and prevents colorectal cancer progression Research Paper

Nandaraj Taye, Aftab Alam, Suvankar Ghorai, Deya Ghosh Chatterji, Apoorva Parulekar, Devraj Mogare, Snahlata Singh, Pallabi Sengupta, Subhrangsu Chatterjee, Manoj Kumar Bhat, Manas Kumar Santra, Prabhakar Budha Salunkhe, Susan Kling Finston, Samit Chattopadhyay

Published Apr 20, 2018 · Vol. 9, No. 30 · pp. 21322-21336

MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma Research Paper

Saurabh Agarwal, Giorgio Milazzo, Kimal Rajapakshe, Ronald Bernardi, Zaowen Chen, Eveline Barberi, Jan Koster, Giovanni Perini, Cristian Coarfa, Jason M. Shohet

Published Apr 17, 2018 · Vol. 9, No. 29 · pp. 20323-20338

Sequential immunotherapy in a patient with primary refractory Hodgkin lymphoma and novel mutations Case Report

Richard Greil, Lisa Pleyer, Bettina Jansko, Carmen Feierabend, Lukas Rettenbacher, Olga Stiefel, Christoph Rass, Patrick Morre, Daniel Neureiter, Sigrun Greil-Ressler

Published Apr 17, 2018 · Vol. 9, No. 29 · pp. 20928-20940

Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity Research Paper

Angela McHugh, Kenneth Fernandes, Andrew P. South, Jemima E. Mellerio, Julio C. Salas-AlanÃs, Charlotte M. Proby, Irene M. Leigh, Mark K. Saville

Published Apr 17, 2018 · Vol. 9, No. 29 · pp. 20265-20281

Infusion of bone marrow derived multipotent mesenchymal stromal cells for the treatment of steroid-refractory acute graft-versus-host disease: a multicenter prospective study Research Paper

Sophie Servais, FrÃ©dÃ©ric Baron, Chantal Lechanteur, Laurence Seidel, Dominik Selleslag, Johan Maertens, Etienne Baudoux, Pierre Zachee, Michel Van Gelder, Lucien Noens, Tessa Kerre, Philippe Lewalle, Wilfried Schroyens, AurÃ©lie Ory, Yves Beguin

Published Apr 17, 2018 · Vol. 9, No. 29 · pp. 20590-20604

Mouse genetic background influences whether Hras^G12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma Research Paper

Laura P. Brandt, Joachim Albers, Tomas Hejhal, Svende Pfundstein, Ana Filipa GonÃ§alves, Antonella Catalano, Peter J. Wild, Ian J. Frew

Published Apr 13, 2018 · Vol. 9, No. 28 · pp. 19753-19766

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Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2 Research Paper

Hitting two oncogenic machineries in cancer cells: cooperative effects of the multi-kinase inhibitor ponatinib and the BET bromodomain blockers JQ1 or dBET1 on human carcinoma cells Research Paper

Translation termination-dependent deadenylation of MYC mRNA in human cells Research Paper

Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins Research Paper

B-glucans from Grifola frondosa and Ganoderma lucidum in breast cancer: an example of complementary and integrative medicine Review

Brief report: RRx-001 is a c-Myc inhibitor that targets cancer stem cells Research Paper

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity Research Paper

Disturbed alternative splicing of FIR (PUF60) directed cyclin E overexpression in esophageal cancers Research Paper

Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma Research Paper

FSH receptor binding inhibitor impacts K-Ras and c-Myc of ovarian cancer and signal pathway Research Paper

Comparative oncology DNA sequencing of canine T cell lymphoma via human hotspot panel Research Paper

Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing Research Paper

Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis Research Paper

MYC gene amplification is a rare event in atypical fibroxanthoma and pleomorphic dermal sarcoma Research Paper

SMAR1 inhibits Wnt/Î²-catenin signaling and prevents colorectal cancer progression Research Paper

MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma Research Paper

Sequential immunotherapy in a patient with primary refractory Hodgkin lymphoma and novel mutations Case Report

Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity Research Paper

Infusion of bone marrow derived multipotent mesenchymal stromal cells for the treatment of steroid-refractory acute graft-versus-host disease: a multicenter prospective study Research Paper

Mouse genetic background influences whether Hras^G12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2 Research Paper

Hitting two oncogenic machineries in cancer cells: cooperative effects of the multi-kinase inhibitor ponatinib and the BET bromodomain blockers JQ1 or dBET1 on human carcinoma cells Research Paper

Translation termination-dependent deadenylation of MYC mRNA in human cells Research Paper

Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins Research Paper

B-glucans from Grifola frondosa and Ganoderma lucidum in breast cancer: an example of complementary and integrative medicine Review

Brief report: RRx-001 is a c-Myc inhibitor that targets cancer stem cells Research Paper

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity Research Paper

Disturbed alternative splicing of FIR (PUF60) directed cyclin E overexpression in esophageal cancers Research Paper

Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma Research Paper

FSH receptor binding inhibitor impacts K-Ras and c-Myc of ovarian cancer and signal pathway Research Paper

Comparative oncology DNA sequencing of canine T cell lymphoma via human hotspot panel Research Paper

Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing Research Paper

Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis Research Paper

MYC gene amplification is a rare event in atypical fibroxanthoma and pleomorphic dermal sarcoma Research Paper

SMAR1 inhibits Wnt/Î²-catenin signaling and prevents colorectal cancer progression Research Paper

MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma Research Paper

Sequential immunotherapy in a patient with primary refractory Hodgkin lymphoma and novel mutations Case Report

Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity Research Paper

Infusion of bone marrow derived multipotent mesenchymal stromal cells for the treatment of steroid-refractory acute graft-versus-host disease: a multicenter prospective study Research Paper

Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma Research Paper

Mouse genetic background influences whether Hras^G12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma Research Paper