The Oncosearch | Oncotarget

Down-regulation of microRNA-320 suppresses cardiomyocyte apoptosis and protects against myocardial ischemia and reperfusion injury by targeting IGF-1 Research Paper

Chun-Li Song, Bin Liu, Hong-Ying Diao, Yong-Feng Shi, Ji-Chang Zhang, Yang-Xue Li, Ning Liu, Yun-Peng Yu, Guan Wang, Jin-Peng Wang, Qian Li

Published May 9, 2016 · Vol. 7, No. 26 · pp. 39740-39757

Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging Research Paper

Ana I. Rodriguez-Perez, Ana Borrajo, Carmen Diaz-Ruiz, Pablo Garrido-Gil, Jose L. Labandeira-Garcia

Published May 4, 2016 · Vol. 7, No. 21 · pp. 30049-30067

Metformin restores crizotinib sensitivity in crizotinib-resistant human lung cancer cells through inhibition of IGF1-R signaling pathway Research Paper

Li Li, Yubo Wang, Tao Peng, Kejun Zhang, Caiyu Lin, Rui Han, Conghua Lu, Yong He

Published Apr 30, 2016 · Vol. 7, No. 23 · pp. 34442-34452

Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX Research Paper

Sung Yong Oh, Aesun Shin, Seong-Geun Kim, Jung-Ah Hwang, Seung Hyun Hong, Yeon-Su Lee, Hyuk-Chan Kwon

Published Apr 29, 2016 · Vol. 7, No. 21 · pp. 31204-31214

Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes Research Paper

Junjie Gao, Tak Sum Cheng, An Qin, Nathan J. Pavlos, Tao Wang, Kai Song, Yan Wang, Lianzhi Chen, Lin Zhou, Qing Jiang, Hiroshi Takayanagi, Sheng Yan, Minghao Zheng

Published Apr 27, 2016 · Vol. 7, No. 19 · pp. 26966-26978

Assessment of red blood cell distribution width as a prognostic marker in chronic lymphocytic leukemia Research Paper

Monika Podhorecka, Dorota Halicka, Agnieszka Szymczyk, Arkadiusz Macheta, Sylwia Chocholska, Marek Hus, Zbigniew Darzynkiewicz

Published Apr 27, 2016 · Vol. 7, No. 22 · pp. 32846-32853

The impact of adjuvant chemotherapy in older breast cancer patients on clinical and biological aging parameters Research Paper

Barbara Brouwers, Sigrid Hatse, Lissandra Dal Lago, Patrick Neven, Peter Vuylsteke, Bruna Dalmasso, Guy Debrock, Heidi Van Den Bulck, Ann Smeets, Oliver Bechter, Jithendra Kini Bailur, Cindy Kenis, Annouschka Laenen, Patrick SchÃ¶ffski, Graham Pawelec, Fabrice Journe, Ghanem-Elias Ghanem, Hans Wildiers

Published Apr 18, 2016 · Vol. 7, No. 21 · pp. 29977-29988

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer Research Paper

Yaqing Chen, Jianchang Qian, Qun He, Hui Zhao, Lourdes Toral-Barza, Celine Shi, Xuesai Zhang, Jiang Wu, Ker Yu

Published Mar 22, 2016 · Vol. 7, No. 18 · pp. 25224-25240

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse Research Paper

Sharon E. Mitchell, Camille Delville, Penelope Konstantopedos, Davina Derous, Cara L. Green, Yingchun Wang, Jing-Dong J. Han, Daniel E.L. Promislow, Alex Douglas, Luonan Chen, David Lusseau, John R. Speakman

Published Mar 17, 2016 · Vol. 7, No. 15 · pp. 19147-19170

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival Research Paper

CatrÃona M. Dowling, James Phelan, Julia A. Callender, Mary Clare Cathcart, Brian Mehigan, Paul McCormick, Tara Dalton, John C. Coffey, Alexandra C. Newton, Jacintha Oâ€™Sullivan, Patrick A. Kiely

Published Mar 14, 2016 · Vol. 7, No. 15 · pp. 20919-20933

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Ji Hyun Park, Yun Jung Choi, Seon Ye Kim, Jung-Eun Lee, Ki Jung Sung, Sojung Park, Woo Sung Kim, Joon Seon Song, Chang-Min Choi, Young Hoon Sung, Jin Kyung Rho, Jae Cheol Lee

Published Mar 9, 2016 · Vol. 7, No. 16 · pp. 22005-22015

Insulin receptor substrate 1 is a substrate of the Pim protein kinases Research Paper

Jin H. Song, Sathish K. R. Padi, Libia A. Luevano, Mark D. Minden, Daniel J. DeAngelo, Gary Hardiman, Lauren E. Ball, Noel A. Warfel, Andrew S. Kraft

Published Mar 4, 2016 · Vol. 7, No. 15 · pp. 20152-20165

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor Research Paper

Sen Liu, Qiuyang Zhang, Chong Chen, Dongxia Ge, Yine Qu, Rongyi Chen, Yi-Ming Fan, Nan Li, Wendell W. Tang, Wensheng Zhang, Kun Zhang, Alun R. Wang, Brian G. Rowan, Steven M. Hill, Oliver Sartor, Asim B. Abdel-Mageed, Leann Myers, Qishan Lin, Zongbing You

Published Feb 10, 2016 · Vol. 7, No. 12 · pp. 13651-13666

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population Research Paper

Ning Li, Huaichao Luo, Xiaoqi Liu, Shi Ma, He Lin, Rong Chen, Fang Hao, Dingding Zhang

Published Dec 16, 2015 · Vol. 7, No. 1 · pp. 23-32

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

Parag P. Patwardhan, Kathryn S. Ivy, Elgilda Musi, Elisa de Stanchina, Gary K. Schwartz

Published Dec 10, 2015 · Vol. 7, No. 4 · pp. 4093-4109

The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells Research Paper

Hui Lyu, XiaoHe Yang, Susan M. Edgerton, Ann D. Thor, Xiaoying Wu, Zhimin He, Bolin Liu

Published Nov 26, 2015 · Vol. 7, No. 3 · pp. 2921-2935

Infiltrating T cells promote renal cell carcinoma (RCC) progression via altering the estrogen receptor β-DAB2IP signals Research Paper

Chiuan-Ren Yeh, Zheng-Yu Ou, Guang-Qian Xiao, Elizabeth Guancial, Shuyuan Yeh

Published Nov 17, 2015 · Vol. 6, No. 42 · pp. 44346-44359

Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer Research Paper

Juan Zhou, Jinjing Wang, Yunyun Zeng, Xi Zhang, Qiaoting Hu, Jihua Zheng, Bei Chen, Bo Xie, Wei-Min Zhang

Published Nov 5, 2015 · Vol. 6, No. 42 · pp. 44332-44345

Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans Research Paper

Neeraj Kumar, Vaibhav Jain, Anupama Singh, Urmila Jagtap, Sonia Verma, Arnab Mukhopadhyay

Published Nov 2, 2015 · Vol. 6, No. 39 · pp. 41418-41433

Liposomal doxorubicin for active targeting: surface modification of the nanocarrier evaluated in vitro and in vivo â€” challenges and prospects Research Paper

Judith Jakoby, Felix Beuschlein, Susanne Mentz, Constanze Hantel, Regine SÃ¼ss

Published Oct 20, 2015 · Vol. 6, No. 41 · pp. 43698-43711

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Down-regulation of microRNA-320 suppresses cardiomyocyte apoptosis and protects against myocardial ischemia and reperfusion injury by targeting IGF-1 Research Paper

Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging Research Paper

Metformin restores crizotinib sensitivity in crizotinib-resistant human lung cancer cells through inhibition of IGF1-R signaling pathway Research Paper

Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX Research Paper

Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes Research Paper

Assessment of red blood cell distribution width as a prognostic marker in chronic lymphocytic leukemia Research Paper

The impact of adjuvant chemotherapy in older breast cancer patients on clinical and biological aging parameters Research Paper

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer Research Paper

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse Research Paper

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival Research Paper

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Insulin receptor substrate 1 is a substrate of the Pim protein kinases Research Paper

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor Research Paper

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population Research Paper

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells Research Paper

Infiltrating T cells promote renal cell carcinoma (RCC) progression via altering the estrogen receptor β-DAB2IP signals Research Paper

Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer Research Paper

Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans Research Paper

Liposomal doxorubicin for active targeting: surface modification of the nanocarrier evaluated in vitro and in vivo â€” challenges and prospects Research Paper

Publication Alerts

European Cancer and Oncology Congress

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Post-Publication Promotion

Search Oncotarget

Down-regulation of microRNA-320 suppresses cardiomyocyte apoptosis and protects against myocardial ischemia and reperfusion injury by targeting IGF-1 Research Paper

Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging Research Paper

Metformin restores crizotinib sensitivity in crizotinib-resistant human lung cancer cells through inhibition of IGF1-R signaling pathway Research Paper

Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX Research Paper

Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes Research Paper

Assessment of red blood cell distribution width as a prognostic marker in chronic lymphocytic leukemia Research Paper

The impact of adjuvant chemotherapy in older breast cancer patients on clinical and biological aging parameters Research Paper

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer Research Paper

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse Research Paper

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival Research Paper

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Insulin receptor substrate 1 is a substrate of the Pim protein kinases Research Paper

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor Research Paper

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population Research Paper

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells Research Paper

Infiltrating T cells promote renal cell carcinoma (RCC) progression via altering the estrogen receptor β-DAB2IP signals Research Paper

Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer Research Paper

Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans Research Paper

Liposomal doxorubicin for active targeting: surface modification of the nanocarrier evaluated in vitro and in vivo â€” challenges and prospects Research Paper