The Oncosearch | Oncotarget

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer Review

Ehsan Malek, Sajjeev Jagannathan, James J. Driscoll

Published Sep 29, 2014 · Vol. 5, No. 18 · pp. 8027-8038

Keywords: non-coding RNAs, long-non-coding RNAs, microRNAs, HOTAIR, overall survival

The IGF signalling pathway in Wilms tumours - A report from the ENCCA Renal Tumours Biology-driven drug development workshop Review

Mariana Maschietto, Jocelyn Charlton, Daniela Perotti, Paolo Radice, James I. Geller, Kathy Pritchard-Jones, Mark Weeks

Published Sep 16, 2014 · Vol. 5, No. 18 · pp. 8014-8026

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity Research Paper

Suganthi Chittaranjan, Susanna Chan, Cindy Yang, Kevin C. Yang, Vincent Chen, Annie Moradian, Marlo Firme, Jungeun Song, Nancy E. Go, Michael D. Blough, Jennifer A. Chan, Gregory J. Cairncross, Sharon M. Gorski, Gregg B. Morin, Stephen Yip, Marco A. Marra

Published Aug 27, 2014 · Vol. 5, No. 17 · pp. 7960-7979

MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells Priority Research Paper

Akriti Kharbanda, Hasan Rajabi, Caining Jin, Maroof Alam, Kwok-Kin Wong, Donald Kufe

Published Aug 22, 2014 · Vol. 5, No. 19 · pp. 8893-8905

Keywords: KRAS, NSCLC, MUC1-C, AKT, ZEB1, EMT, self-renewal

SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma Research Paper

Jeffrey Wojton, Walter Hans Meisen, Naduparambil K. Jacob, Amy Haseley Thorne, Jayson Hardcastle, Nicholas Denton, Zhengtao Chu, Nina Dmitrieva, Rachel Marsh, Erwin G. Van Meir, Chang-Hyuk Kwon, Arnab Chakravarti, Xiaoyang Qi, Balveen Kaur

Published Jul 17, 2014 · Vol. 5, No. 20 · pp. 9703-9709

Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors Research Paper

VÃctor M. Blanco, Zhengtao Chu, Subrahmanya D. Vallabhapurapu, Mahaboob K. Sulaiman, Ady Kendler, Olivier Rixe, Ronald E. Warnick, Robert S. Franco, Xiaoyang Qi

Published Jul 14, 2014 · Vol. 5, No. 16 · pp. 7105-7118

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model Research Paper

Juozas Vasiliauskas, Madison A. Nashu, Peterson Pathrose, Sandra L. Starnes, Susan E. Waltz

Published Jun 26, 2014 · Vol. 5, No. 14 · pp. 5547-5558

Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands Review

Pradip De, Jennifer Carlson, Brian Leyland-Jones, Nandini Dey

Published Jun 22, 2014 · Vol. 5, No. 13 · pp. 4581-4602

Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals Research Paper

Laura Gatti, Alexandra Sevko, Michelandrea De Cesare, Noemi Arrighetti, Giacomo Manenti, Emilio Ciusani, Paolo Verderio, Chiara M. Ciniselli, Denis Cominetti, Nives Carenini, Elisabetta Corna, Nadia Zaffaroni, Monica Rodolfo, Licia Rivoltini, Viktor Umansky, Paola Perego

Published Jun 6, 2014 · Vol. 5, No. 12 · pp. 4516-4528

High nuclear level of Vav1 is a positive prognostic factor in early invasive breast tumors: a role in modulating genes related to the efficiency of metastatic process Research Paper

Silvia Grassilli, Federica Brugnoli, Rossano Lattanzio, Cosmo Rossi, Letizia Perracchio, Marcella Mottolese, Marco Marchisio, Maria Palomba, Ervin Nika, Pier Giorgio Natali, Mauro Piantelli, Silvano Capitani, Valeria Bertagnolo

Published May 25, 2014 · Vol. 5, No. 12 · pp. 4320-4336

miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma Research Paper

Emanuela Minna, Paola Romeo, Loris De Cecco, Matteo Dugo, Giuliana Cassinelli, Silvana Pilotti, Debora Deglâ€™Innocenti, Cinzia Lanzi, Patrizia Casalini, Marco A. Pierotti, Angela Greco, Maria Grazia Borrello

Published Mar 16, 2014 · Vol. 5, No. 9 · pp. 2513-2528

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Adrienne L. Watson, Bryant J. Keller, Kyle A. Williams, Namrata N. Damle, Samuel J. Finnerty, Leah K. Anderson, Andrew D. Greeley, Vincent W. Keng, Eric P. Rahrmann, Amanda L. Halfond, Natasha M. Powell, Margaret H. Collins, Tilat Rizvi, Christopher L. Moertel, Nancy Ratner, David A. Largaespada

Published Jan 20, 2014 · Vol. 5, No. 6 · pp. 1502-1514

Keywords: Malignant peripheral nerve sheath tumors, plexiform neurofibromas, Schwann cells, neurofibromatosis type 1 syndrome, neurofibromin 1, PI3K/AKT/mTOR signaling, MAPK signaling, targeted therapies, genetically engineered mouse models, combination therapy

Perspectives of TGF-Î² inhibition in pancreatic and hepatocellular carcinomas Review

Cindy Neuzillet, Armand de Gramont, AnnemilaÃ¯ Tijeras-Raballand, Louis de Mestier, JÃ©rÃ´me Cros, Sandrine Faivre, Eric Raymond

Published Dec 18, 2013 · Vol. 5, No. 1 · pp. 78-94

Keywords: SMAD, stellate cells, extracellular matrix, EMT, TGF-Î² inhibitors

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

Sandra Cascio, Adam M Farkas, Rebecca P Hughey, Olivera J Finn

Published Sep 7, 2013 · Vol. 4, No. 10 · pp. 1686-1697

Keywords: MUC1, CIN85, protein-protein interaction, cell migration, metastasis, novel targets, glycosylation

The predictive value of 53BP1 and BRCA1 mRNA expression in advanced non-small-cell lung cancer patients treated with first-line platinum-based chemotherapy Research Paper

Laura Bonanno, Carlota Costa, Margarita Majem, Jose Javier Sanchez, Ana Gimenez-Capitan, Ignacio Rodriguez, Alain Vergenegre, Bartomeu Massuti, Adolfo Favaretto, Massimo Rugge, Cinta Pallares, Miquel Taron, Rafael Rosell

Published Jul 31, 2013 · Vol. 4, No. 10 · pp. 1572-1581

Keywords: BRCA1, 53BP1, DNA repair, predictive modeling, platinum

PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1 Research Paper

Alexander Gont, Jennifer E. L. Hanson, Sylvie J. Lavictoire, Doris A. E. Parolin, Manijeh Daneshmand, Ian J. restall, Mathieu Soucie, Garth Nicholas, John Woulfe, Amin Kassam, Vasco F. Da Silva, Ian A. J. Lorimer

Published Jul 21, 2013 · Vol. 4, No. 8 · pp. 1266-1279

Keywords: glioblastoma, glioma, PTEN, atypical PKC, Lgl, tumor initiating cell

Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia (AML) Research Paper

Harald Herrmann, Katharina Blatt, Junwei Shi, Karoline V. Gleixner, Sabine Cerny-Reiterer, Leonhard MÃ¼llauer, Christopher R. Vakoc, Wolfgang R. Sperr, Hans-Peter Horny, James E. Bradner, Johannes Zuber, Peter Valent

Published Nov 27, 2012 · Vol. 3, No. 12 · pp. 1588-1599

Keywords: AML, leukemic stem cells, BRD4, JQ1, targeted therapy

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

Andrew D Beggs, Enric Domingo, Megan McGregor, Mikael Presz, Elaine Johnstone, Rachel Midgley, David Kerr, Dahmane Oukrif, Marco Novelli, Muti Abulafi, Shirley V Hodgson, Wakkas Fadhil, Mohammed Ilyas, Ian P Tomlinson

Published Oct 28, 2012 · Vol. 3, No. 11 · pp. 1348-1355

Keywords: Double strand break repair, ATM, g-H2AX, colorectal cancer, prognosis

Cyclin D1 Induces Chromosomal Instability Editorial Comments

Mathew C. Casimiro, Richard G. Pestell

Published Apr 15, 2012 · Vol. 3, No. 3 · pp. 224-225

Keywords: Cyclin D1, ChIP-Seq, CIN

Capturing the Molecular and Biological Diversity of High-Grade Astrocytoma in Genetically Engineered Mouse Models Research Perspective

Lionel M.L. Chow, Suzanne J. Baker

Published Jan 25, 2012 · Vol. 3, No. 1 · pp. 67-77

Keywords: glioblastoma, astrocytoma, mouse model, PI3K pathway

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Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer Review

The IGF signalling pathway in Wilms tumours - A report from the ENCCA Renal Tumours Biology-driven drug development workshop Review

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity Research Paper

MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells Priority Research Paper

SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma Research Paper

Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors Research Paper

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model Research Paper

Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands Review

Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals Research Paper

High nuclear level of Vav1 is a positive prognostic factor in early invasive breast tumors: a role in modulating genes related to the efficiency of metastatic process Research Paper

miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Perspectives of TGF-Î² inhibition in pancreatic and hepatocellular carcinomas Review

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

The predictive value of 53BP1 and BRCA1 mRNA expression in advanced non-small-cell lung cancer patients treated with first-line platinum-based chemotherapy Research Paper

PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1 Research Paper

Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia (AML) Research Paper

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

Cyclin D1 Induces Chromosomal Instability Editorial Comments

Capturing the Molecular and Biological Diversity of High-Grade Astrocytoma in Genetically Engineered Mouse Models Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer Review

The IGF signalling pathway in Wilms tumours - A report from the ENCCA Renal Tumours Biology-driven drug development workshop Review

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity Research Paper

MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells Priority Research Paper

SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma Research Paper

Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors Research Paper

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model Research Paper

Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands Review

Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals Research Paper

High nuclear level of Vav1 is a positive prognostic factor in early invasive breast tumors: a role in modulating genes related to the efficiency of metastatic process Research Paper

miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Perspectives of TGF-Î² inhibition in pancreatic and hepatocellular carcinomas Review

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

The predictive value of 53BP1 and BRCA1 mRNA expression in advanced non-small-cell lung cancer patients treated with first-line platinum-based chemotherapy Research Paper

PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1 Research Paper

Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia (AML) Research Paper

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

Cyclin D1 Induces Chromosomal Instability Editorial Comments

Capturing the Molecular and Biological Diversity of High-Grade Astrocytoma in Genetically Engineered Mouse Models Research Perspective