The Oncosearch | Oncotarget

Genetic biomarkers predict response to dual BCL-2 and MCL-1 targeting in acute myeloid leukaemia cells Research Paper

Martin Grundy, Sahana Balakrishnan, Matthew Fox, Claire H. Seedhouse, Nigel H. Russell

Published Dec 28, 2018 · Vol. 9, No. 102 · pp. 37777-37789

IGFBP2 is a potential biomarker in acute kidney injury (AKI) and resveratrol-loaded nanoparticles prevent AKI Research Paper

Hai-Lun Li, Zhuan Yan, Zun-Ping Ke, Xiao-Feng Tian, Li-Li Zhong, Yong-Tao Lin, Yong Xu, Dong-Hui Zheng

Published Nov 27, 2018 · Vol. 9, No. 93 · pp. 36551-36560

Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma Research Paper

Shariful Islam, Andrew L. Paek, Michael Hammer, Savithri Rangarajan, Robert Ruijtenbeek, Laurence Cooke, Eric Weterings, Daruka Mahadevan

Published Nov 13, 2018 · Vol. 9, No. 89 · pp. 35875-35890

BH4-mimetics and -antagonists: an emerging class of Bcl-2 protein modulators for cancer therapy Editorial

Adrien NougarÃ¨de, Ruth Rimokh, Germain Gillet

Published Oct 15, 2018 · Vol. 9, No. 82 · pp. 35291-35292

Generation and characteristics of a novel â€œdouble-hitâ€ high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies Research Paper

Hiroaki Kikuchi, Tomonori Higuchi, Yumiko Hashida, Ayuko Taniguchi, Mikio Kamioka, Takahiro Taguchi, Akihito Yokoyama, Ichiro Murakami, Mikiya Fujieda, Masanori Daibata

Published Sep 11, 2018 · Vol. 9, No. 71 · pp. 33482-33499

Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines Research Paper

Moses Koobotse, Jeff Holly, Claire Perks

Published Sep 11, 2018 · Vol. 9, No. 71 · pp. 33562-33576

Panobinostat mediated cell death: a novel therapeutic approach for osteosarcoma Research Paper

AndrÃ© Wirries, Samir Jabari, Esther P. Jansen, Silvia Roth, Elizabeth Figueroa-JuÃ¡rez, Thaddeus T. Wissniowski, Daniel Neureiter, Eckhard Klieser, Philipp Lechler, Steffen Ruchholtz, Detlef K. Bartsch, Christoph K. Boese, Pietro Di Fazio

Published Aug 31, 2018 · Vol. 9, No. 68 · pp. 32997-33010

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers Research Paper

Kalliopi Tsafou, Anna Maria Katschnig, Branka Radic-Sarikas, Cornelia NoÃ«lle Mutz, Kristiina Iljin, Raphaela Schwentner, Maximilian O. Kauer, Karin MÃ¼hlbacher, Dave N.T. Aryee, David Westergaard, Saija Haapa-Paananen, Vidal Fey, Giulio Superti-Furga, Jeffrey Toretsky, SÃ¸ren Brunak, Heinrich Kovar

Published Jul 24, 2018 · Vol. 9, No. 57 · pp. 31018-31031

Autophagy processes are dependent on EGF receptor signaling Research Paper

Vincenzo De Iuliis, Antonio Marino, Marika Caruso, Sabrina Capodifoglio, Vincenzo Flati, Anna Marynuk, Valeria Marricareda, Sebastiano Ursi, Paola Lanuti, Claudio Talora, Pio Conti, Stefano Martinotti, Elena Toniato

Published Jul 13, 2018 · Vol. 9, No. 54 · pp. 30289-30303

MYC-related microRNAs signatures in non-Hodgkin B-cell lymphomas and their relationships with core cellular pathways Research Paper

Giorgio Malpeli, Stefano Barbi, Gabriele Tosadori, Corinna Greco, Simonetta Zupo, Serena Pedron, Matteo Brunelli, Anna Bertolaso, Maria Teresa Scupoli, Mauro Krampera, Paul Takam Kamga, Carlo Maria Croce, George Adrian Calin, Aldo Scarpa, Alberto ZamÃ²

Published Jul 3, 2018 · Vol. 9, No. 51 · pp. 29753-29771

BET inhibition in advanced cutaneous T cell lymphoma is synergistically potentiated by BCL2 inhibition or HDAC inhibition Research Paper

Sa Rang Kim, Julia M. Lewis, Benoit M. Cyrenne, Patrick F. Monico, Fatima N. Mirza, Kacie R. Carlson, Francine M. Foss, Michael Girardi

Published Jun 26, 2018 · Vol. 9, No. 49 · pp. 29193-29207

The organic ester O,O'-diethyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis Research Paper

Milena Jurisevic, Aleksandar Arsenijevic, Jelena Pantic, Nevena Gajovic, Jelena Milovanovic, Marija Milovanovic, Jelena Poljarevic, Tibor Sabo, Danilo Vojvodic, Gordana D. Radosavljevic, Nebojsa Arsenijevic

Published Jun 15, 2018 · Vol. 9, No. 46 · pp. 28195-28212

Metronomic combination of Vinorelbine and 5Fluorouracil is able to inhibit triple-negative breast cancer cells. Results from the proof-of-concept VICTOR-0 study Research Paper

Maria Grazia Cerrito, Marco De Giorgi, Davide Pelizzoni, Sara Maria Bonomo, Nunzio Digiacomo, Arianna Scagliotti, Cristina Bugarin, Giuseppe Gaipa, Emanuela Grassilli, Marialuisa Lavitrano, Roberto Giovannoni, Paolo Bidoli, Marina Elena Cazzaniga

Published Jun 8, 2018 · Vol. 9, No. 44 · pp. 27448-27459

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2 Research Paper

Shinya Ishida, Hiroki Akiyama, Yoshihiro Umezawa, Keigo Okada, Ayako Nogami, Gaku Oshikawa, Toshikage Nagao, Osamu Miura

Published Jun 1, 2018 · Vol. 9, No. 42 · pp. 26834-26851

Steviol, a natural product inhibits proliferation of the gastrointestinal cancer cells intensively Research Paper

Junming Chen, Yongmei Xia, Xiaochen Sui, Qingrui Peng, Tongtong Zhang, Jian Li, Jue Zhang

Published May 29, 2018 · Vol. 9, No. 41 · pp. 26299-26308

Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia Research Paper

Joachim R. GÃ¶thert, Roze Imsak, Michael MÃ¶llmann, Stefanie Kesper, Maria GÃ¶bel, Ulrich DÃ¼hrsen, Arne Scholz, Ulrich LÃ¼cking, Matthias Baumann, Anke Unger, Carsten Schultz-Fademrecht, Bert Klebl, Jan Eickhoff, Axel Choidas, Jan DÃ¼rig

Published May 29, 2018 · Vol. 9, No. 41 · pp. 26353-26369

BCL2 and BCL(X)L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2-deoxy-D-glucose Research Paper

Federico Lucantoni, Heiko DÃ¼ssmann, Irene Llorente-Folch, Jochen H.M. Prehn

Published May 25, 2018 · Vol. 9, No. 40 · pp. 26046-26063

Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells Research Paper

Martin C. Pearce, John T. Gamble, Prasad R. Kopparapu, Edmond F. O'Donnell, Monica J. Mueller, Hyo Sang Jang, Julie A. Greenwood, Arnold C. Satterthwait, Roberta L. Tanguay, Xiao-Kun Zhang, Siva Kumar Kolluri

Published May 25, 2018 · Vol. 9, No. 40 · pp. 26072-26085

Synthetic lethality in CCNE1-amplified high grade serous ovarian cancer through combined inhibition of Polo-like kinase 1 and microtubule dynamics Research Paper

Sabrina Noack, Monika Raab, Yves Matthess, Mourad Sanhaji, Andrea KrÃ¤mer, BalÃ¡zs GyÅ‘rffy, Lars Kaderali, Ahmed El-Balat, Sven Becker, Klaus Strebhardt

Published May 25, 2018 · Vol. 9, No. 40 · pp. 25842-25859

Bcl-2 inhibition sensitizes triple-negative human breast cancer cells to doxorubicin Research Paper

Touko Inao, Yuichi Iida, Tamami Moritani, Tamio Okimoto, Ryosuke Tanino, Hitoshi Kotani, Mamoru Harada

Published May 22, 2018 · Vol. 9, No. 39 · pp. 25545-25556

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Genetic biomarkers predict response to dual BCL-2 and MCL-1 targeting in acute myeloid leukaemia cells Research Paper

IGFBP2 is a potential biomarker in acute kidney injury (AKI) and resveratrol-loaded nanoparticles prevent AKI Research Paper

Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma Research Paper

BH4-mimetics and -antagonists: an emerging class of Bcl-2 protein modulators for cancer therapy Editorial

Generation and characteristics of a novel â€œdouble-hitâ€ high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies Research Paper

Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines Research Paper

Panobinostat mediated cell death: a novel therapeutic approach for osteosarcoma Research Paper

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers Research Paper

Autophagy processes are dependent on EGF receptor signaling Research Paper

MYC-related microRNAs signatures in non-Hodgkin B-cell lymphomas and their relationships with core cellular pathways Research Paper

BET inhibition in advanced cutaneous T cell lymphoma is synergistically potentiated by BCL2 inhibition or HDAC inhibition Research Paper

The organic ester O,O'-diethyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis Research Paper

Metronomic combination of Vinorelbine and 5Fluorouracil is able to inhibit triple-negative breast cancer cells. Results from the proof-of-concept VICTOR-0 study Research Paper

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2 Research Paper

Steviol, a natural product inhibits proliferation of the gastrointestinal cancer cells intensively Research Paper

Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia Research Paper

BCL2 and BCL(X)L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2-deoxy-D-glucose Research Paper

Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells Research Paper

Synthetic lethality in CCNE1-amplified high grade serous ovarian cancer through combined inhibition of Polo-like kinase 1 and microtubule dynamics Research Paper

Bcl-2 inhibition sensitizes triple-negative human breast cancer cells to doxorubicin Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Genetic biomarkers predict response to dual BCL-2 and MCL-1 targeting in acute myeloid leukaemia cells Research Paper

IGFBP2 is a potential biomarker in acute kidney injury (AKI) and resveratrol-loaded nanoparticles prevent AKI Research Paper

Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma Research Paper

BH4-mimetics and -antagonists: an emerging class of Bcl-2 protein modulators for cancer therapy Editorial

Generation and characteristics of a novel â€œdouble-hitâ€ high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies Research Paper

Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines Research Paper

Panobinostat mediated cell death: a novel therapeutic approach for osteosarcoma Research Paper

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers Research Paper

Autophagy processes are dependent on EGF receptor signaling Research Paper

MYC-related microRNAs signatures in non-Hodgkin B-cell lymphomas and their relationships with core cellular pathways Research Paper

BET inhibition in advanced cutaneous T cell lymphoma is synergistically potentiated by BCL2 inhibition or HDAC inhibition Research Paper

The organic ester O,O'-diethyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis Research Paper

Metronomic combination of Vinorelbine and 5Fluorouracil is able to inhibit triple-negative breast cancer cells. Results from the proof-of-concept VICTOR-0 study Research Paper

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2 Research Paper

Steviol, a natural product inhibits proliferation of the gastrointestinal cancer cells intensively Research Paper

Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia Research Paper

BCL2 and BCL(X)L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2-deoxy-D-glucose Research Paper

Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells Research Paper

Synthetic lethality in CCNE1-amplified high grade serous ovarian cancer through combined inhibition of Polo-like kinase 1 and microtubule dynamics Research Paper

Bcl-2 inhibition sensitizes triple-negative human breast cancer cells to doxorubicin Research Paper

Generation and characteristics of a novel â€œdouble-hitâ€ high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies Research Paper