The Oncosearch | Oncotarget

AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells Research Paper

Yarong Song, Peng Zhang, Yadong Sun, Xuechao Li, Lifeng Chen, Yajun Xiao, Yifei Xing

Published Jul 4, 2017 · Vol. 8, No. 40 · pp. 67942-67954

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer Research Paper

Jair Machado Espindola-Netto, Claudia C.S. Chini, Mariana TarragÃ³, Enfeng Wang, Shamit Dutta, Krishnendu Pal, Debabrata Mukhopadhyay, Mauro Sola-Penna, Eduardo N. Chini

Published Jun 29, 2017 · Vol. 8, No. 49 · pp. 85054-85067

Dual inhibition of glycolysis and glutaminolysis as a therapeutic strategy in the treatment of ovarian cancer Research Paper

Li Sun, Yajie Yin, Leslie H. Clark, Wenchuan Sun, Stephanie A. Sullivan, Arthur-Quan Tran, Jianjun Han, Lu Zhang, Hui Guo, Esther Madugu, Tommy Pan, Amanda L. Jackson, Joshua Kilgore, Hannah M. Jones, Timothy P. Gilliam, Chunxiao Zhou, Victoria L. Bae-Jump

Published Jun 29, 2017 · Vol. 8, No. 38 · pp. 63551-63561

Silencing protein kinase C ζ by microRNA-25-5p activates AMPK signaling and inhibits colorectal cancer cell proliferation Research Paper

Shihu Zhang, Yiyang Zhang, Qing Cheng, Zhaoqun Ma, Guanwen Gong, Zhengming Deng, Kun Xu, Gaoyuan Wang, Yousong Wei, Xiaoping Zou

Published Jun 27, 2017 · Vol. 8, No. 39 · pp. 65329-65338

Reverse phase protein array (RPPA) combined with computational analysis to unravel relevant prognostic factors in non- small cell lung cancer (NSCLC): a pilot study Case Report

Vienna Ludovini, Rita Chiari, Lorenzo Tomassoni, Chiara Antonini, Elisa Baldelli, Sara Baglivo, Annamaria Siggillino, Francesca Romana Tofanetti, Guido Bellezza, K. Alex Hodge, Emanuel Petricoin, Mariaelena Pierobon, Lucio CrinÃ², Fortunato Bianconi

Published Jun 14, 2017 · Vol. 8, No. 47 · pp. 83343-83353

A novel AMPK activator hernandezine inhibits LPS-induced TNFα production Research Paper

Ping Li, Xiaofang Li, Yonghong Wu, Manxiang Li, Xiaochuang Wang

Published Jun 5, 2017 · Vol. 8, No. 40 · pp. 67218-67226

Blocking epithelial-to-mesenchymal transition in glioblastoma with a sextet of repurposed drugs: the EIS regimen Research Perspective

Richard E. Kast, Nicolas Skuli, Georg Karpel-Massler, Guido Frosina, Timothy Ryken, Marc-Eric Halatsch

Published Jun 1, 2017 · Vol. 8, No. 37 · pp. 60727-60749

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN Research Paper

Andrea Cavazzoni, Silvia La Monica, Roberta Alfieri, Andrea Ravelli, Nele Van Der Steen, Rocco Sciarrillo, Denise Madeddu, Costanza Anna Maria Lagrasta, Federico Quaini, Mara Bonelli, Claudia Fumarola, Daniele Cretella, Graziana Digiacomo, Marcello Tiseo, Godefridus J. Peters, Andrea Ardizzoni, Pier Giorgio Petronini, Elisa Giovannetti

Published May 23, 2017 · Vol. 8, No. 32 · pp. 53068-53083

BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity Research Paper

Hexige Saiyin, Ning Na, Xu Han, Yuan Fang, Yanhua Wu, Wenhui Lou, Xianmei Yang

Published May 18, 2017 · Vol. 8, No. 27 · pp. 44669-44681

6-mercaptopurine promotes energetic failure in proliferating T cells Research Paper

Ana A. FernÃ¡ndez-Ramos, Catherine Marchetti-Laurent, Virginie Poindessous, Samantha Antonio, Pierre Laurent-Puig, Sylvie Bortoli, Marie-Anne Loriot, Nicolas Pallet

Published May 16, 2017 · Vol. 8, No. 26 · pp. 43048-43060

A novel synthetic derivative of quercetin, 8-trifluoromethyl-3,5,7,3â€²,4â€²-O-pentamethyl-quercetin, inhibits bladder cancer growth by targeting the AMPK/mTOR signaling pathway Research Paper

Ting Tao, Caimei He, Jun Deng, Yanjun Huang, Qiongli Su, Mei Peng, Meiling Yi, Kwame Oteng Darko, Hui Zou, Xiaoping Yang

Published May 11, 2017 · Vol. 8, No. 42 · pp. 71657-71671

Metformin increases chemo-sensitivity via gene downregulation encoding DNA replication proteins in 5-Fu resistant colorectal cancer cells Research Paper

Sung-Hee Kim, Soon-Chan Kim, Ja-Lok Ku

Published May 11, 2017 · Vol. 8, No. 34 · pp. 56546-56557

Dual degradation signals destruct GLI1: AMPK inhibits GLI1 through β-TrCP-mediated proteasome degradation Research Paper

Rui Zhang, Sherri Y. Huang, Kay Ka-Wai Li, Yen-Hsing Li, Wei-Hsuan Hsu, GuangJun Zhang, Chun-Ju Chang, Jer-Yen Yang

Published May 10, 2017 · Vol. 8, No. 30 · pp. 49869-49881

RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis Research Paper

Akemi Takata, Motoyuki Otsuka, Takahiro Kishikawa, Mari Yamagami, Rei Ishibashi, Kazuma Sekiba, Tatsunori Suzuki, Motoko Ohno, Yui Yamashita, Takaya Abe, Ryota Masuzaki, Tsuneo Ikenoue, Kazuhiko Koike

Published May 4, 2017 · Vol. 8, No. 39 · pp. 64840-64852

Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectal cancer Research Paper

Jin-Lai Wei, Min Fang, Zhong-Xue Fu, Shouâ€“Ru Zhang, Jin-Bao Guo, Rong Wang, Zhen-Bing Lv, Yong-Fu Xiong

Published May 3, 2017 · Vol. 8, No. 30 · pp. 49318-49328

Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials Review

Michael Troncone, Stephanie M. Cargnelli, Linda A. Villani, Naghmeh Isfahanian, Lindsay A. Broadfield, Laura Zychla, Jim Wright, Gregory Pond, Gregory R. Steinberg, Theodoros Tsakiridis

Published Apr 27, 2017 · Vol. 8, No. 34 · pp. 57733-57754

Trans-scirpusin A showed antitumor effects via autophagy activation and apoptosis induction of colorectal cancer cells Research Paper

Eun-Hye Hong, Eun-Young Heo, Jae-Hyoung Song, Bo-Eun Kwon, Jae-Young Lee, Yaejeong Park, Jinwoong Kim, Sun-Young Chang, Young-Won Chin, Sang-Min Jeon, Hyun-Jeong Ko

Published Apr 24, 2017 · Vol. 8, No. 25 · pp. 41401-41411

Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells Research Paper

Mark Borris D. Aldonza, Yeon Sung Son, Hye-Jin Sung, Jung Mo Ahn, Young-Jin Choi, Yong-In Kim, Sukki Cho, Je-Yoel Cho

Published Apr 12, 2017 · Vol. 8, No. 26 · pp. 42817-42835

Zerumbone ameliorates high-fat diet-induced adiposity by restoring AMPK-regulated lipogenesis and microRNA-146b/SIRT1-mediated adipogenesis Research Paper

Jiyun Ahn, Hyunjung Lee, Chang Hwa Jung, Won Hee Choi, Tae Youl Ha

Published Apr 8, 2017 · Vol. 8, No. 23 · pp. 36984-36995

Inhibition of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation Research Paper

Xiulong Xu, Jing Sun, Ruilong Song, Michelle E. Doscas, Ashley J. Williamson, Jingsong Zhou, Jun Sun, Xinan Jiao, Xiufan Liu, Yi Li

Published Mar 31, 2017 · Vol. 8, No. 18 · pp. 30438-30454

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AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells Research Paper

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer Research Paper

Dual inhibition of glycolysis and glutaminolysis as a therapeutic strategy in the treatment of ovarian cancer Research Paper

Silencing protein kinase C ζ by microRNA-25-5p activates AMPK signaling and inhibits colorectal cancer cell proliferation Research Paper

Reverse phase protein array (RPPA) combined with computational analysis to unravel relevant prognostic factors in non- small cell lung cancer (NSCLC): a pilot study Case Report

A novel AMPK activator hernandezine inhibits LPS-induced TNFα production Research Paper

Blocking epithelial-to-mesenchymal transition in glioblastoma with a sextet of repurposed drugs: the EIS regimen Research Perspective

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN Research Paper

BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity Research Paper

6-mercaptopurine promotes energetic failure in proliferating T cells Research Paper

A novel synthetic derivative of quercetin, 8-trifluoromethyl-3,5,7,3â€²,4â€²-O-pentamethyl-quercetin, inhibits bladder cancer growth by targeting the AMPK/mTOR signaling pathway Research Paper

Metformin increases chemo-sensitivity via gene downregulation encoding DNA replication proteins in 5-Fu resistant colorectal cancer cells Research Paper

Dual degradation signals destruct GLI1: AMPK inhibits GLI1 through β-TrCP-mediated proteasome degradation Research Paper

RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis Research Paper

Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectal cancer Research Paper

Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials Review

Trans-scirpusin A showed antitumor effects via autophagy activation and apoptosis induction of colorectal cancer cells Research Paper

Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells Research Paper

Zerumbone ameliorates high-fat diet-induced adiposity by restoring AMPK-regulated lipogenesis and microRNA-146b/SIRT1-mediated adipogenesis Research Paper

Inhibition of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells Research Paper

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer Research Paper

Dual inhibition of glycolysis and glutaminolysis as a therapeutic strategy in the treatment of ovarian cancer Research Paper

Silencing protein kinase C ζ by microRNA-25-5p activates AMPK signaling and inhibits colorectal cancer cell proliferation Research Paper

Reverse phase protein array (RPPA) combined with computational analysis to unravel relevant prognostic factors in non- small cell lung cancer (NSCLC): a pilot study Case Report

A novel AMPK activator hernandezine inhibits LPS-induced TNFα production Research Paper

Blocking epithelial-to-mesenchymal transition in glioblastoma with a sextet of repurposed drugs: the EIS regimen Research Perspective

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN Research Paper

BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity Research Paper

6-mercaptopurine promotes energetic failure in proliferating T cells Research Paper

A novel synthetic derivative of quercetin, 8-trifluoromethyl-3,5,7,3â€²,4â€²-O-pentamethyl-quercetin, inhibits bladder cancer growth by targeting the AMPK/mTOR signaling pathway Research Paper

Metformin increases chemo-sensitivity via gene downregulation encoding DNA replication proteins in 5-Fu resistant colorectal cancer cells Research Paper

Dual degradation signals destruct GLI1: AMPK inhibits GLI1 through β-TrCP-mediated proteasome degradation Research Paper

RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis Research Paper

Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectal cancer Research Paper

Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials Review

Trans-scirpusin A showed antitumor effects via autophagy activation and apoptosis induction of colorectal cancer cells Research Paper

Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells Research Paper

Zerumbone ameliorates high-fat diet-induced adiposity by restoring AMPK-regulated lipogenesis and microRNA-146b/SIRT1-mediated adipogenesis Research Paper

Inhibition of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation Research Paper