The Oncosearch | Oncotarget

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Bhumika Wadhwa, Masroor Paddar, Sameer Khan, Sameer Mir, Philip A.Clarke, Anna M. Grabowska, Devanahalli G. Vijay, Fayaz Malik

Published Sep 8, 2020 · Vol. 11, No. 45 · pp. 4178-4194

Keywords: AKT isoform, CSCs, ABCG2, drug resistance, TNBCs

Preclinical evaluation of the anti-tumor activity of pralatrexate in high-risk neuroblastoma cells Research Paper

Rachael A. Clark, Sora Lee, Jingbo Qiao, Dai H. Chung

Published Jul 23, 2020 · Vol. 11, No. 32 · pp. 3069-3077

Keywords: neuroblastoma, pralatrexate, N-myc, folate metabolism

Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry Research Paper

Janos Schmidt, Béla Kajtár, Kata Juhász, Mária Péter, Tamás Járai, András Burián, László Kereskai, Imre Gerlinger, Tamás Tornóczki, Gábor Balogh, László Vígh, Lászó Márk, Zsolt Balogi

Published Jun 11, 2020 · Vol. 11, No. 28 · pp. 2702-2717

Keywords: Imaging mass spectrometry, tumor marker, lipid tumor marker, S100A8, S100A9

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Hee-Don Chae, Ritika Dutta, Bruce Tiu, Fieke W. Hoff, Benedetta Accordi, Valentina Serafin, Minyoung Youn, Min Huang, Nathan Sumarsono, Kara L. Davis, Norman J. Lacayo, Martina Pigazzi, Terzah M. Horton, Steven M. Kornblau, Kathleen M. Sakamoto

Published May 26, 2020 · Vol. 11, No. 25 · pp. 2387-2403

Keywords: acute myeloid leukemia, BI-D1870, RSK, vincristine, spindle assembly checkpoint

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast Research Paper

Pamela Dakik, Monica Enith Lozano Rodriguez, Jennifer Anne Baratang Junio, Darya Mitrofanova, Younes Medkour, Tala Tafakori, Tarek Taifour, Vicky Lutchman, Eugenie Samson, Anthony Arlia-Ciommo, Belise Rukundo, Éric Simard, Vladimir I. Titorenko

Published May 23, 2020 · Vol. 11, No. 23 · pp. 2182-2203

Keywords: cellular aging, longevity, gerotargets, geroprotectors, plant extracts

Hereditary pancreatitis model by blastocyst complementation in mouse Research Paper

Ayumu Asai, Masamitsu Konno, Koichi Kawamoto, Ayako Isotani, Masaki Mori, Hidetoshi Eguchi, Yuichiro Doki, Takahiro Arai, Hideshi Ishii

Published May 2, 2020 · Vol. 11, No. 22 · pp. 2061-2073

Keywords: blastocyst complementation, hereditary pancreatitis, disease-specific pluripotent stem cells, PRSS1

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Abhijit Chakraborty, Faisal Aziz, Eunmiri Roh, Le Thi My Le, Raja Dey, Tianshun Zhang, Moeez G. Rathore, Aalekhya Sharma Biswas, Ann M. Bode, Zigang Dong

Published Apr 17, 2020 · Vol. 11, No. 20 · pp. 1846-1861

Keywords: TIMELESS, TIPIN, apoptosis, xenograft, Cryo-EM

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

James R. Browning, Paige Derr, Kristy Derr, Nicole Doudican, Sam Michael, Samantha R. Lish, Nicholas A. Taylor, James G. Krueger, Marc Ferrer, John A. Carucci, Daniel S. Gareau

Published Apr 16, 2020 · Vol. 11, No. 27 · pp. 2587-2596

Keywords: squamous cell carcinoma, screening, 3D printing, in vitro model, confocal microscopy

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1 Research Paper

Hisham S. Alhajala, John L. Markley, Jin Hae Kim, Mona M. Al-Gizawiy, Kathleen M. Schmainda, John S. Kuo, Christopher R. Chitambar

Published Apr 15, 2020 · Vol. 11, No. 17 · pp. 1531-1544

Keywords: glioblastoma, iron, gallium, metformin, mitochondrial complex I

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

David J. Lamb, Aleksander Rust, Albin Rudisch, Tobias Glüxam, Nathalie Harrer, Herwig Machat, Ingrid Christ, Florian Colbatzky, Andreas Wernitznig, Annika Osswald, Wolfgang Sommergruber

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1257-1272

Keywords: SYK inhibitor, breast carcinoma, 3D culture, murine mammary gland, proliferation

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

Nerymar Ortiz-Otero, Andrea B. Clinch, Jacob Hope, Wenjun Wang, Cynthia A. Reinhart-King, Michael R. King

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1037-1050

Keywords: metastasis, cancer associated fibroblasts, circulating tumor cells, cytoprotection, collective migration

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Kouki Okita, Shogo Okazaki, Shinya Uejima, Erina Yamada, Hiroki Kaminaka, Misa Kondo, Shiho Ueda, Ryo Tokiwa, Nami Iwata, Akitaka Yamasaki, Natsumi Hayashi, Dai Ogura, Kenji Hirotani, Toshiaki Yoshioka, Masahiro Inoue, Kazue Masuko, Takashi Masuko

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 31-45

Keywords: CDR, HER3, internalization, mAb, NRG1

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells Research Paper

Farah Ballout, Alissar Monzer, Maamoun Fatfat, Hala El Ouweini, Miran A. Jaffa, Rana Abdel-Samad, Nadine Darwiche, Wassim Abou-Kheir, Hala Gali-Muhtasib

Published Jan 3, 2020 · Vol. 11, No. 31 · pp. 2959-2972

Keywords: thymoquinone, colorectal cancer stem cells, 5-Fluorouracil resistance, colonospheres, apoptosis

Mesangiogenic progenitor cells are forced toward the angiogenic fate, in multiple myeloma Research Paper

Simone Pacini, Marina Montali, Francesco Mazziotta, Claudia P. Schifone, Lucia Macchia, Vittoria Carnicelli, Francesca M. Panvini, Serena Barachini, Laura Notarfranchi, Giovanni Battista Previti, Gabriele Buda, Mario Petrini

Published Nov 26, 2019 · Vol. 10, No. 63 · pp. 6781-6790

Keywords: multiple myeloma, bone marrow microenvironment, angiogenesis, osteogenesis, mesangiogenic progenitor cells

miR-151a enhances Slug dependent angiogenesis Priority Research Paper

Douglas Jury, Iben Daugaard, Katie J. Sanders, Lise Lotte Hansen, Dritan Agalliu, Irene Munk Pedersen

Published Nov 7, 2019 · Vol. 11, No. 23 · pp. 2160-2171

Keywords: angiogenesis, miR-151a, Slug, tumor microenvironment, endothelial cell

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Andrew J. Sanders, Sioned Owen, Liam D. Morgan, Fiona Ruge, Ross J. Collins, Lin Ye, Malcolm D. Mason, Wen G. Jiang

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6362-6377

Keywords: ALCAM, prostate cancer, bone, metastasis, serum biomarker

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Manti Guha, Satish Srinivasan, Maura M. Sheehan, Takashi Kijima, Gordon Ruthel, Kelly Whelan, Koji Tanaka, Andres Klein-Szanto, Prasanna M. Chandramouleeswaran, Hiroshi Nakagawa, Narayan G. Avadhani

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6245-6259

Keywords: mitochondrial DNA, MPV17, ESCC, telomere, 3D organoid

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Andrew J. Sanders, Sioned Owen, Liam Morgan, Fiona Ruge, Ross Collins, Lin Ye, Malcolm Mason, Wenguo Jiang

Published Oct 14, 2019

Keywords: ALCAM, prostate cancer, bone, metastasis, serum biomarker

Correction: POPX2 is a novel LATS phosphatase that regulates the Hippo pathway Correction

Muhammad Bakhait Rahmat, Songjing Zhang, Cheng-Gee Koh

Published Oct 3, 2019 · Vol. 10, No. 56 · pp. 5890-5891

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Michelle M. Williams, David L. Elion, Bushra Rahman, Donna J. Hicks, Violeta Sanchez, Rebecca S. Cook

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5389-5402

Keywords: Mcl-1, ABT-263 resistance, mTORC1 signaling, luminal breast cancers

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AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Preclinical evaluation of the anti-tumor activity of pralatrexate in high-risk neuroblastoma cells Research Paper

Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry Research Paper

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast Research Paper

Hereditary pancreatitis model by blastocyst complementation in mouse Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1 Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells Research Paper

Mesangiogenic progenitor cells are forced toward the angiogenic fate, in multiple myeloma Research Paper

miR-151a enhances Slug dependent angiogenesis Priority Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Correction: POPX2 is a novel LATS phosphatase that regulates the Hippo pathway Correction

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Preclinical evaluation of the anti-tumor activity of pralatrexate in high-risk neuroblastoma cells Research Paper

Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry Research Paper

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast Research Paper

Hereditary pancreatitis model by blastocyst complementation in mouse Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1 Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells Research Paper

Mesangiogenic progenitor cells are forced toward the angiogenic fate, in multiple myeloma Research Paper

miR-151a enhances Slug dependent angiogenesis Priority Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Correction: POPX2 is a novel LATS phosphatase that regulates the Hippo pathway Correction

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper