Retraction:
Retraction: Long non-coding RNA ANRIL promotes the invasion and metastasis of thyroid cancer cells through TGF-β/Smad signaling pathway
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1 Department of Breast, Thyroid, and Vascular Surgery, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, 400042, P. R. China
Published: December 31, 2025
Copyright: © 2025 Zhao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This article has been retracted: Oncotarget has concluded its investigation of this paper. Multiple instances of internal and external duplications and overlaps of Transwell assy images were discovered. These include:
Internal Duplications:
Figure 5, TPC-1, panel A is a duplicate of SW579 panels A and B, and correspondingly SW579 panels A and B are duplicates too.
Figure 5, TPC-1, panel E overlaps with SW579 panel D.
Figure 6, TPC-1 panel A overlaps with panel B.
External Duplications:
Figures 5 and 6 contain panels that overlap with earlier published figures 7 and 12 in already retracted article [1] and Figure 8D in article [2]. Concurrently published papers [3] and [4] also shred images from Figures 5 and 6. And multiple panels from Figures 5 and 6 were found in later published unrelated articles [5–8].
The authors and their institution have been contacted, but neither has responded. Therefore, the Editorial decision has been made to retract the paper.
REFERENCES
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5. Li E, Zhao Z, Ma B, Zhang J. Long noncoding RNA HOTAIR promotes the proliferation and metastasis of osteosarcoma cells through the AKT/mTOR signaling pathway. Exp Ther Med. 2017; 14:5321–28. https://doi.org/10.3892/etm.2017.5248.. [PubMed].
6. Guo HM, Yang SH, Zhao SZ, Li L, Yan MT, Fan MC. LncRNA NEAT1 regulates cervical carcinoma proliferation and invasion by targeting AKT/PI3K. Eur Rev Med Pharmacol Sci. 2018; 22:4090–97. https://doi.org/10.26355/eurrev_201807_15400.. [PubMed].
7. Zhao ZW, Fan XX, Song JJ, Xu M, Chen MJ, Tu JF, Wu FZ, Zhang DK, Liu L, Chen L, Ying XH, Ji JS. ShRNA knock-down of CXCR7 inhibits tumour invasion and metastasis in hepatocellular carcinoma after transcatheter arterial chemoembolization. J Cell Mol Med. 2017; 21:1989–99. https://doi.org/10.1111/jcmm.13119.. [PubMed].
8. Qiao B, He BX, Cai JH, Tao Q, King-Yin Lam A. MicroRNA-27a-3p Modulates the Wnt/β-Catenin Signaling Pathway to Promote Epithelial-Mesenchymal Transition in Oral Squamous Carcinoma Stem Cells by Targeting SFRP1. Sci Rep. 2017; 7:44688. https://doi.org/10.1038/srep44688.. [PubMed]. Retraction in: Sci Rep. 2020; 10:21317. https://doi.org/10.1038/s41598-020-77203-x.. [PubMed].
Original article: Oncotarget. 2016; 7:57903–57918. DOI: https://doi.org/10.18632/oncotarget.11087.
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