Oncotarget

Retraction:

Retraction: ATG4A promotes tumor metastasis by inducing the epithelial-mesenchymal transition and stem-like properties in gastric cells

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Oncotarget. 2025; 16:868-868. https://doi.org/10.18632/oncotarget.28795

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Shi-Wei Yang1,2, Yi-Fang Ping2,3, Yu-Xing Jiang1, Xiao Luo1, Xia Zhang2,3, Xiu-Wu Bian2,3, Pei-Wu Yu1

1 Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China
2 Key Laboratory of Tumor Immunopathology of Ministry of Education of China, Third Military Medical University, Chongqing, China
3 Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, Chongqing, China

Published: December 31, 2025

Copyright: © 2025 Yang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

This article has been retracted: Oncotarget has completed its investigation of this article. The investigation shows duplication in Figures 1, 2 and 5. Corresponding author Peiwu-Yu supplied files for a correction. However, it was then discovered that the gastric cancer cell lines SGC-7901 and MGC-803, used in this study, have been reported as contaminated [1–4]. Given the extent of the identified issues, the editors have lost confidence in the data presented and the article’s conclusions can no longer be considered reliable. Therefore, the Editorial decision was made to retract this paper. The authors have been informed of the concerns and the decision to retract. The authors have not acknowledged that their data has been compromised and their conclusions are invalid.


REFERENCES

1. Ye F, Chen C, Qin J, Liu J, Zheng C. Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China. FASEB J. 2015; 29:4268–72. https://doi.org/10.1096/fj.14-266718.. [PubMed].

2. Bian X, Yang Z, Feng H, Sun H, Liu Y. A Combination of Species Identification and STR Profiling Identifies Cross-contaminated Cells from 482 Human Tumor Cell Lines. Sci Rep. 2017; 7:9774. https://doi.org/10.1038/s41598-017-09660-w.. [PubMed].

3. Cao F, Sun H, Yang Z, Bai Y, Hu X, Hou Y, Bian X, Liu Y. Multiple approaches revealed MGc80-3 as a somatic hybrid with HeLa cells rather than a gastric cancer cell line. Int J Cancer. 2024; 154:155–68. https://doi.org/10.1002/ijc.34677.. [PubMed].

4. Yang M, He J, Xia S, Wang Y, Xiong J, Liao C, Li N, Qu S, Shen C. Investigation of the mixed origins of the MGC-803 cell line reveals that it is a hybrid cell line derived from HeLa. Hum Cell. 2024; 37:560–66. https://doi.org/10.1007/s13577-023-01011-4.. [PubMed]. Correction in: Hum Cell. 2024; 37:567. https://doi.org/10.1007/s13577-024-01027-4.. [PubMed].

Original article: Oncotarget. 2016; 7:39279–39292. DOI: https://doi.org/10.18632/oncotarget.9827.


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