Corrections:

Nicholas Cho^1,2, Sooah Ko² and Monica Shokeen^1,2,3

¹Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA
²Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA
³Alvin J. Siteman Cancer Center, Washington University School of Medicine and Barnes-Jewish Hospital, St. Louis, MO, USA

Published: April 11, 2025

Copyright: © 2025 Cho et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

This article has been corrected: Oncotarget’s investigation of the paper is now complete. We’ve determined that in Figure 3A, the Day 0 representative image of MM.1S SQ mice in the “DARA-IR” group was unintentionally duplicated from the Day 2 image, taken before the fluorescent imaging. This error happened during the figure assembly process. The authors have removed the Day 0 images for both groups of mice. As stated in the Figure 3A caption, the figure is intended to show mice at days 2 and 9 post-dye administration. The authors declare that these modifications to the figures do not change the results or conclusions of the paper.

Original article: Oncotarget. 2021; 12:2039-2050. DOI: https://doi.org/10.18632/oncotarget.28074.

Figure 3: High contrast observed with DARA-DM1-IR at longer time points in MM.1S SQ mice.
(A) Representative IRDye800 in vivo images of MM.1S SQ mice 2 and 9 days post administration of DARA-DM1-IR and DARA-IR.
(B) Plot of calculated Tumor to Background Ratios (TBRs) in MM.1S SQ mice across individual time points following administration of DARA-DM1-IR and DARA-IR. Background is defined as the non-tumor, contralateral left flank of the mouse. Repeated measures two-way ANOVA followed by Sidak’s multiple comparison’s test was performed on TBR data. n = 3–4/group.
(C) Normalized biodistribution (defined as tissue to muscle ratio (TMR)) of DARA-DM1-IR 2, 7 and 9 days after administration of fluorescent conjugate. n = 3–4/group. Two-way ANOVA followed by Sidak’s multiple comparisons test was performed on biodistribution data.
(D) Immunohistochemistry of excised tumor sections from mice injected with DARA-DM1-IR and DARA-IR. Nuclear stain was performed with Hoechst 33342. Magnification: 40×; Scale bar: 100 μm.
*p < 0.05; **p < 0.01; ***p < 0.0001. Error bars represent standard deviation.