Research Papers:

Yonsei criteria: a clinical reflection of stage I left-sided pancreatic cancer

Jae Uk Chong, Sung Hyun Kim, Ho Kyoung Hwang, Chang Moo Kang _ and Woo Jung Lee

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Oncotarget. 2017; 8:110830-110836. https://doi.org/10.18632/oncotarget.22734

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Jae Uk Chong1,2, Sung Hyun Kim1,2, Ho Kyoung Hwang1,2, Chang Moo Kang1,2 and Woo Jung Lee1,2

1Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea

2Pancreaticobiliary Cancer Clinic, Yonsei Cancer Center, Severance Hospital, Seoul, Korea

Correspondence to:

Chang Moo Kang, email: [email protected]

Keywords: pancreatic cancer; TNM staging; survival analysis; disease-free survival; pancreatectomy

Received: September 07, 2017     Accepted: November 13, 2017     Published: November 28, 2017


In this study, we examined associations between pancreatic cancer that met the Yonsei criteria (YC) and classifications from the 8th edition of the American Joint Committee on Cancer (AJCC) staging system. Clinicopathological and survival data were collected from132 patients who underwent distal pancreatectomy for left-sided pancreatic ductal adenocarcinoma between January 2000 and December 2015, and the utility of the YC for selecting treatment and predicting survival was evaluated using the 8th AJCC staging manual. Of the 102 patients who ultimately qualified for the study, 45 patients were reclassified as stage I based on the 8th AJCC cancer staging system. Disease-free survival and disease-specific survival periods were longer in stage I patients who met the YC than in those who did not. Clinicopathological characteristics did not differ between stage I patients who did and did not meet the YC. These results suggest that meeting the YC criteria may be a clinical indicator that left-sided pancreatic cancer patients who are candidates for resection have early-stage disease according to the 8th edition of the AJCC staging manual.

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