Clinical Research Papers:

Trends in the incidence of AIDS and epidemiological features in Tianjin, China from 2005 to 2016

Ping Ma, Liying Gao, Defa Zhang, Aiping Yu, Chunting Qiu, Lei Li, Fangfang Yu, Yue Wu, Wei You, Yanyun Guo, Xianjia Ning and Wei Lu _

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Oncotarget. 2017; 8:102540-102549. https://doi.org/10.18632/oncotarget.21016

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Ping Ma1,*, Liying Gao1,*, Defa Zhang1, Aiping Yu1, Chunting Qiu1, Lei Li1, Fangfang Yu1, Yue Wu1, Wei You1, Yanyun Guo1, Xianjia Ning2,3,4 and Wei Lu1

1Department of Infectious Disease, Tianjin Second People’s Hospital, Tianjin 300192, China

2Center of Epidemiology and Department of Neurology, Tianjin Medical University General Hospital, Tianjin 300052, China

3Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin 300052, China

4Department of Epidemiology, Tianjin Neurological Institute, Tianjin 300052, China

*These authors are contributed equally to this work

Correspondence to:

Wei Lu, email: [email protected]

Keywords: AIDS, epidemiology, incidence, trends, China

Received: July 07, 2017     Accepted: August 27, 2017     Published: September 18, 2017


The objective of this study was to assess the epidemiological trends among patients with AIDS in Tianjin, China. A long-term surveillance study was conducted from 2005 to 2016 in Tianjin, China. All patients with AIDS registered in Tianjin from 2005 to 2016 were recruited to this study. Demographic information and clinical features were recorded. A total of 3062 patients with AIDS who were treated with antiretroviral therapy were included in this study. Among AIDS patients, men were more likely to be younger than women (age, 37.84 years vs. 43.27 years; P < 0.001). The incidence of AIDS increased by 39.6% annually over the past 12 years overall. There was the greatest increase (by 44.7%) for homosexual route. Moreover, the proportion of patients aged < 30 years increased considerably over the 12-year study period, while there was a decrease in the proportion of patients aged ≥ 35 years. The frequency of homosexual transmission increased by 86% from before 2011 to 2016, but the frequency of heterosexual transmission decreased by 49%. The frequency of transmission through intravenous drug use decreased in men and patients aged 25–29 years. For those infected through homosexual transmission, there was a significant increase in the numbers of patients aged 20–24 years and 25–29 years. It is important for developing countries to effectively prevent and control the transmission of HIV/AIDS; in particular, it is crucial to promote disease education and sexual protection among young men.

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