Clinical Research Papers:

The value of radiographic indexes in the diagnosis of discogenic low back pain: a retrospective analysis of imaging results

Jian Song, Hong-Li Wang, Xiao-Sheng Ma, Xin-Lei Xia, Fei-Zhou Lu, Chao-Jun Zheng and Jian-Yuan Jiang _

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Oncotarget. 2017; 8:60558-60567. https://doi.org/10.18632/oncotarget.18652

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Jian Song1,*, Hong-Li Wang1,*, Xiao-Sheng Ma1,#, Xin-Lei Xia1,#, Fei-Zhou Lu1,#, Chao-Jun Zheng1 and Jian-Yuan Jiang1

1Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, 200040, China

*These authors have contributed equally to this work


Correspondence to:

Jian-Yuan Jiang, email: [email protected], [email protected]

Keywords: discogenic low back pain, angular motion, modic change, HIZ

Received: March 22, 2017     Accepted: May 23, 2017     Published: June 27, 2017


To explore value of different radiographic indexes in the diagnosis of discogenic low back pain (LBP). A total number of 120 cases (60 patients diagnosed with discogenic LBP and 60 healthy people) were retrospectively analysed to identify factors in the diagnosis of discogenic LBP by using univariate and multivariate analyses. A receiver operating characteristic (ROC) curve was drew to show the predictive accuracy of the finally enrolled factors. Among all the included patients, 60 were strictly admitted in the discogenic LBP group while the other 60 were enrolled in the control group. Five results shows significant differences between discogenic LBP and control groups, including Cobb angle, lumbar stability, height of the disc, Modic change and High intense zone (HIZ) based on the results of univariate analysis; lumbar stability, Modic change and HIZ show high value in the diagnosis of lumbar discogenic pain based on the multivariate logistic analysis.The ROC curve shows that good diagnostic accuracy was obtained from the enrolled diagnostic factors including lumbar stability (Angular motion, more than 14.35°), Modic change and HIZ.

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