Parkin-mediated mitophagy ameliorates fatty acid-induced mitochondrial injury and apoptosis in tubular epithelial cells by reducing oxidative stress

Yue Wu; Jiangmin Wan; Xuemei Chen; Wei Hua; Haibo Gui; Xushun Jiang; Huizhe Huang; Xiongzhong Ruan; Xiaogang Du

doi:10.18632/oncotarget.23682

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Withdrawal Notice

This paper was originally published in Oncotarget Advance Online Publications on 12/26/2017.
In compliance with Oncotarget's withdrawal policy, the paper was withdrawn in its entirety. It will not appear in Oncotarget internal or any external indexes or archives.

Research Papers:

Parkin-mediated mitophagy ameliorates fatty acid-induced mitochondrial injury and apoptosis in tubular epithelial cells by reducing oxidative stress

Yue Wu, Jiangmin Wan, Xuemei Chen, Wei Hua, Haibo Gui, Xushun Jiang, Huizhe Huang, Xiongzhong Ruan and Xiaogang Du _

Yue Wu1,*, Jiangmin Wan1,2,*, Xuemei Chen3,*, Wei Hua4, Haibo Gui3, Xushun Jiang1, Huizhe Huang5, Xiongzhong Ruan6,7 and Xiaogang Du1,8

1 Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

2 Department of Nephrology, People’s Hospital of Qijiang Distract, Chongqing, China

3 Emergency Department, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

4 Department of Nephrology, The Sixth People’s Hospital of Chongqing, Chongqing, China

5 The second Affiliated Hospital of Chongqing Medical University, Chongqing, China

6 Centre for Nephrology, Royal Free and University College Medical School, University College London, Royal Free Campus, London, United Kingdom

7 Centre for Lipid Research, Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, China

8 The Chongqing Key Laboratory of Translational Medicine in Major Metabolic Disease, Chongqing, China

* These authors contributed equally to this work

Correspondence:

Xiaogang Du, email: [email protected]

Keywords: parkin; mitophagy; palmitic acid; tubular epithelial cells; apoptosis

Received: October 07, 2016 Accepted: December 18, 2017 Epub: December 26, 2017

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PII: 23682

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Research Papers:

Parkin-mediated mitophagy ameliorates fatty acid-induced mitochondrial injury and apoptosis in tubular epithelial cells by reducing oxidative stress