Oncotarget

View Archive »

About The Cover

Chromosome transplantation as a novel approach for correcting complex genomic disorders. See Paulis et al.

Table of Contents

Editorial

Tumorbinding antibodies and tumor immunity

https://doi.org/10.18632/oncotarget.4889

Yaron Carmi, and Edgar G. Engleman
35129-35130
Abstract  |  PDF  |  How to cite

TLR2 – an innate immune checkpoint in multiple sclerosis

https://doi.org/10.18632/oncotarget.6031

Md Jakir Hossain, Radu Tanasescu, and Bruno Gran
35131-35132
Abstract  |  PDF  |  How to cite

Longistatin in ticksaliva targets RAGE

https://doi.org/10.18632/oncotarget.6032

Anisuzzaman, M. Abdul Alim, and Naotoshi Tsuji
35133-35134
Abstract  |  PDF  |  How to cite

RBPJ and ITAM crosstalk

https://doi.org/10.18632/oncotarget.6034

Baohong Zhao
35135-35136
Abstract  |  PDF  |  How to cite

EPIX4 a novel endogenous antagonist of CXCR4

https://doi.org/10.18632/oncotarget.6037

Christian Buske, Frank Kirchhoff, and Jan Münch
35137-35138
Abstract  |  PDF  |  How to cite

AMPK potentiation by LKB1 isoforms

https://doi.org/10.18632/oncotarget.6127

Chantal Thibert, Christine Perret, and Marc Billaud
35139-35140
Abstract  |  PDF  |  How to cite

Metabolic plasticity of cancer stem cells

https://doi.org/10.18632/oncotarget.6177

Ming Luo, and Max S. Wicha
35141-35142
Abstract  |  PDF  |  How to cite

Editorial: Immunology

A framework for T cell assays

https://doi.org/10.18632/oncotarget.6181

Cedrik M. Britten, Sjoerd H. van der Burg, and Cécile Gouttefangeas
35143-35144
Abstract  |  PDF  |  How to cite

Editorial: Autophagy and Cell Death

Metabolism and iron signaling in ferroptotic cell death

https://doi.org/10.18632/oncotarget.5671

Minghui Gao, Prashant Monian, and Xuejun Jiang
35145-35146
Abstract  |  PDF  |  How to cite

Lysosomal mTORC2/PHLPP1/Akt axis: a new point of control of chaperonemediated autophagy

https://doi.org/10.18632/oncotarget.5903

Esperanza Arias
35147-35148
Abstract  |  PDF  |  How to cite

The PHD2 oxygen sensor paves the way to metastasis

https://doi.org/10.18632/oncotarget.6216

Anna Kuchnio, Mieke Dewerchin, and Peter Carmeliet
35149-35150
Abstract  |  PDF  |  How to cite

Editorial: Chromosome

Epigenetic reprogramming in the mammalian germline

https://doi.org/10.18632/oncotarget.6206

Fei-Man Hsu, Amander Clark, and Pao-Yang Chen
35151-35152
Abstract  |  PDF  |  How to cite

Prmt5 differentiates developmental vs regenerative myogenesis

https://doi.org/10.18632/oncotarget.6207

Ting Zhang, Thomas Braun, and Yonggang Zhou
35153-35154
Abstract  |  PDF  |  How to cite

Coping with cancer genes altered by copy number

https://doi.org/10.18632/oncotarget.6215

Natalie K. Wolf, David A. Largaespada, and Branden S. Moriarity
35155-35156
Abstract  |  PDF  |  How to cite

Priority Research Papers

Aspirin lysine mifepristone and doxycycline combined can effectively and safely prevent and treat cancer metastasis: prevent seeds from gemmating on soil

https://doi.org/10.18632/oncotarget.6038

Liyuan Wan, Haiyan Dong, Huo Xu, Ji Ma, Yewei Zhu, Yusheng Lu, Jichuang Wang, Ting Zhang, Tao Li, Jingjing Xie, Bo Xu, Fangwei Xie, Yu Gao, Jingwei Shao, Xiaohuang Tu, and Lee Jia
35157-35172
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP

https://doi.org/10.18632/oncotarget.6050

Xiaolan Deng, Gottfried Von Keudell, Takehiro Suzuki, Naoshi Dohmae, Makoto Nakakido, Lianhua Piao, Yuichiro Yoshioka, Yusuke Nakamura, and Ryuji Hamamoto
35173-35182
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenetic silencing of miR1455p contributes to brain metastasis

https://doi.org/10.18632/oncotarget.5930

Sara Donzelli, Federica Mori, Teresa Bellissimo, Andrea Sacconi, Beatrice Casini, Tania Frixa, Giuseppe Roscilli, Luigi Aurisicchio, Francesco Facciolo, Alfredo Pompili, Maria Antonia Carosi, Edoardo Pescarmona, Oreste Segatto, Greg Pond, Paola Muti, Stefano Telera, Sabrina Strano, Yosef Yarden, and Giovanni Blandino
35183-35201
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MCL1independent mechanisms of synergy between dual PI3K/mTOR and BCL2 inhibition in diffuse large B cell lymphoma

https://doi.org/10.18632/oncotarget.6051

J. Scott Lee, Sarah S. Tang, Veronica Ortiz, Thanh-Trang Vo, and David A. Fruman
35202-35217
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Chromosome transplantation as a novel approach for correcting complex genomic disorders

https://doi.org/10.18632/oncotarget.6143

Marianna Paulis, Alessandra Castelli, Lucia Susani, Michela Lizier, Irina Lagutina, Maria Luisa Focarelli, Camilla Recordati, Paolo Uva, Francesca Faggioli, Tui Neri, Eugenio Scanziani, Cesare Galli, Franco Lucchini, Anna Villa, and Paolo Vezzoni
35218-35230
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation while individual pathway activation supports cell persistence

https://doi.org/10.18632/oncotarget.6159

Keyata N. Thompson, Rebecca A. Whipple, Jennifer R. Yoon, Michael Lipsky, Monica S. Charpentier, Amanda E. Boggs, Kristi R. Chakrabarti, Lekhana Bhandary, Lindsay K. Hessler, Stuart S. Martin, and Michele I. Vitolo
35231-35246
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Aurora B kinase is a potent and selective target in MYCNdriven neuroblastoma

https://doi.org/10.18632/oncotarget.6208

Dominik Bogen, Jun S. Wei, David O. Azorsa, Pinar Ormanoglu, Eugen Buehler, Rajarshi Guha, Jonathan M. Keller, Lesley A. Mathews Griner, Marc Ferrer, Young K. Song, Hongling Liao, Arnulfo Mendoza, Berkley E. Gryder, Sivasish Sindri, Jianbin He, Xinyu Wen, Shile Zhang, John F. Shern, Marielle E. Yohe, Sabine Taschner-Mandl, Jason M. Shohet, Craig J. Thomas, Scott E. Martin, Peter F. Ambros, and Javed Khan
35247-35262
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

RAGE mediated intracellular Aβ uptake contributes to the breakdown of tight junction in retinal pigment epithelium

https://doi.org/10.18632/oncotarget.5894

Sung Wook Park, Jin Hyoung Kim, Sang Min Park, Minho Moon, Kihwang Lee, Kyu Hyung Park, Woo Jin Park, and Jeong Hun Kim
35263-35273
Abstract  |  PDF  |  Full Text  |  How to cite

Rapamycin preserves gut homeostasis during Drosophila aging

https://doi.org/10.18632/oncotarget.5895

Xiaolan Fan, Qing Liang, Ting Lian, Qi Wu, Uma Gaur, Diyan Li, Deying Yang, Xueping Mao, Zhihua Jin, Ying Li, and Mingyao Yang
35274-35283
Abstract  |  PDF  |  Full Text  |  How to cite

Viscoelastic and ultrastructural characteristics of whole blood and plasma in Alzheimertype dementia and the possible role of bacterial lipopolysaccharides LPS

https://doi.org/10.18632/oncotarget.6074

Janette Bester, Prashilla Soma, Douglas B. Kell, and Etheresia Pretorius
35284-35303
Abstract  |  PDF  |  Full Text  |  How to cite

Protease activated receptor1 regulates macrophagemediated cellular senescence: a risk for idiopathic pulmonary fibrosis

https://doi.org/10.18632/oncotarget.6095

Cong Lin, Farhad Rezaee, Maaike Waasdorp, Kun Shi, Tom van der Poll, Keren Borensztajn, and C. Arnold Spek
35304-35314
Abstract  |  PDF  |  Full Text  |  How to cite

IGF1 mediated phosphorylation of specific IRS1 serines in Ames dwarf fibroblasts is associated with longevity

https://doi.org/10.18632/oncotarget.6112

John Papaconstantinou, and Ching-Chyuan Hsieh
35315-35323
Abstract  |  PDF  |  Full Text  |  How to cite

Insights into the role of immunosenescence during varicella zoster virus infection shingles in the aging cell model

https://doi.org/10.18632/oncotarget.6117

Ji-Ae Kim, Seul-Ki Park, Mukesh Kumar, Chan-Hee Lee, and Ok Sarah Shin
35324-35343
Abstract  |  PDF  |  Full Text  |  How to cite

Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: a mechanistic insight

https://doi.org/10.18632/oncotarget.6119

Stefania Rigacci, Caterina Miceli, Chiara Nediani, Andrea Berti, Roberta Cascella, Daniela Pantano, Pamela Nardiello, Ilaria Luccarini, Fiorella Casamenti, and Massimo Stefani
35344-35357
Abstract  |  PDF  |  Full Text  |  How to cite

Agedependent uncoupling of mitochondria from Ca2+ release units in skeletal muscle

https://doi.org/10.18632/oncotarget.6139

Laura Pietrangelo, Alessandra D’Incecco, Alina Ainbinder, Antonio Michelucci, Helmut Kern, Robert T. Dirksen, Simona Boncompagni, and Feliciano Protasi
35358-35371
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR215p and miR126a3p levels in plasma and circulating angiogenic cells: relationship with type 2 diabetes complications

https://doi.org/10.18632/oncotarget.6164

Fabiola Olivieri, Liana Spazzafumo, Massimiliano Bonafè, Rina Recchioni, Francesco Prattichizzo, Fiorella Marcheselli, Luigina Micolucci, Emanuela Mensà, Angelica Giuliani, Gabriele Santini, Mirko Gobbi, Raffaella Lazzarini, Massimo Boemi, Roberto Testa, Roberto Antonicelli, Antonio Domenico Procopio, and Anna Rita Bonfigli
35372-35382
Abstract  |  PDF  |  Full Text  |  How to cite

Moderate exercise training attenuates aginginduced cardiac inflammation hypertrophy and fibrosis injuries of rat hearts

https://doi.org/10.18632/oncotarget.6168

Po-Hsiang Liao, Dennis Jine-Yuan Hsieh, Chia-Hua Kuo, Cecilia-Hsuan Day, Chia-Yao Shen, Chao-Hung Lai, Ray-Jade Chen, V. Vijaya Padma, Wei- Wen Kuo, and Chih-Yang Huang
35383-35394
Abstract  |  PDF  |  Full Text  |  How to cite

Association between serum uric acid and bone health in general population: a large and multicentre study

https://doi.org/10.18632/oncotarget.6173

Xianfeng Lin, Chenchen Zhao, An Qin, Dun Hong, Wenyue Liu, Kangmao Huang, Jian Mo, Hejun Yu, Shengjie Wu, and Shunwu Fan
35395-35403
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

cMaf regulates pluripotency genes proliferation/selfrenewal and lineage commitment in ROSmediated senescence of human mesenchymal stem cells

https://doi.org/10.18632/oncotarget.6178

Pei-Min Chen, Chia-Hua Lin, Nan-Ting Li, Yao-Ming Wu, Ming-Tsan Lin, Shih-Chieh Hung, and Men-Luh Yen
35404-35418
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumorhost signaling interaction reveals a systemic agedependent splenic immune influence on tumor development

https://doi.org/10.18632/oncotarget.6214

Afshin Beheshti, Justin Wage, J. Tyson McDonald, Clare Lamont, Michael Peluso, Philip Hahnfeldt, and Lynn Hlatky
35419-35432
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

Genetic variations of body weight and GCRV resistance in a random mating population of grass carp

https://doi.org/10.18632/oncotarget.5945

Rong Huang, Jiaxian Sun, Qing Luo, Libo He, Lanjie Liao, Yongming Li, Fuhua Guo, Zuoyan Zhu, and Yaping Wang
35433-35442
Abstract  |  PDF  |  Full Text  |  How to cite

Dendritic and Langerhans cells respond to Aβ peptides differently: implication for AD immunotherapy

https://doi.org/10.18632/oncotarget.6123

Jiang Cheng, Xiaoyang Lin, David Morgan, Marcia Gordon, Xi Chen, Zhen-Hai Wang, Hai-Ning Li, Lan-Jie He, Shu-Feng Zhou, and Chuanhai Cao
35443-35457
Abstract  |  PDF  |  Full Text  |  How to cite

The ON:OFF switch σ1RHINT1 protein controls GPCRNMDA receptor crossregulation: Implications in neurological disorders

https://doi.org/10.18632/oncotarget.6064

María Rodríguez-Muñoz, Elsa Cortés-Montero, Andrea Pozo-Rodrigálvarez, Pilar Sánchez-Blázquez, and Javier Garzón-Niño
35458-35477
Abstract  |  PDF  |  Full Text  |  How to cite

The activation of EGFR promotes myocardial tumor necrosis factorα production and cardiac failure in endotoxemia

https://doi.org/10.18632/oncotarget.6071

Xuegang Sun, Jiani Liang, Xueqing Yao, Chunhua Lu, Tianyu Zhong, Xiaoyang Hong, Xiaofei Wang, Wenjuan Xu, Miaoning Gu, and Jing Tang
35478-35495
Abstract  |  PDF  |  Full Text  |  How to cite

Cordycepin prevents oxidative stressinduced inhibition of osteogenesis

https://doi.org/10.18632/oncotarget.6072

Feng Wang, Peipei Yin, Ye Lu, Zubin Zhou, Chaolai Jiang, Yingjie Liu, and Xiaowei Yu
35496-35508
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reviews: Gerotarget (Focus on Aging)

DNA damage response DDR and senescence: shuttled inflammamiRNAs on the stage of inflammaging

https://doi.org/10.18632/oncotarget.5899

Fabiola Olivieri, Maria Cristina Albertini, Monia Orciani, Artan Ceka, Monica Cricca, Antonio Domenico Procopio, and Massimiliano Bonafè
35509-35521
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targets

https://doi.org/10.18632/oncotarget.5849

Wensheng Liu, Zaklina Kovacevic, Zhihai Peng, Runsen Jin, Puxiongzhi Wang, Fei Yue, Minhua Zheng, Michael L-H. Huang, Patric J. Jansson, Vera Richardson, Danuta S. Kalinowski, Darius J.R. Lane, Angelica M. Merlot, Sumit Sahni, and Des R. Richardson
35522-35541
Abstract  |  PDF  |  Full Text  |  How to cite

Adaptive responses of androgen receptor signaling in castrationresistant prostate cancer

https://doi.org/10.18632/oncotarget.4689

Sven Perner, Marcus V. Cronauer, Andres Jan Schrader, Helmut Klocker, Zoran Culig, and Aria Baniahmad
35542-35555
Abstract  |  PDF  |  Full Text  |  How to cite

Leptin signalling obesity and prostate cancer: molecular and clinical perspective on the old dilemma

https://doi.org/10.18632/oncotarget.5574

Heba Alshaker, Keith Sacco, Albandri Alfraidi, Aun Muhammad, Mathias Winkler, and Dmitri Pchejetski
35556-35563
Abstract  |  PDF  |  Full Text  |  How to cite

Free intraperitoneal tumor cells and outcome in gastric cancer patients: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.5595

Mathieu Pecqueux, Johannes Fritzmann, Mariam Adamu, Kristian Thorlund, Christoph Kahlert, Christoph Reißfelder, Jürgen Weitz, and Nuh N. Rahbari
35564-35578
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Wnt/βcatenin an oncogenic pathway targeted by H pylori in gastric carcinogenesis

https://doi.org/10.18632/oncotarget.5758

Xiaowen Song, Na Xin, Wei Wang, and Chenghai Zhao
35579-35588
Abstract  |  PDF  |  Full Text  |  How to cite

What links BRAF to the heart function new insights from the cardiotoxicity of BRAF inhibitors in cancer treatment

https://doi.org/10.18632/oncotarget.5853

Enrico Bronte, Giuseppe Bronte, Giuseppina Novo, Fabrizio Bronte, Maria Grazia Bavetta, Giuseppe Lo Re, Giuseppe Brancatelli, Viviana Bazan, Clara Natoli, Salvatore Novo, and Antonio Russo
35589-35601
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

The predictive value of centre tumour CD8+ T cells in patients with hepatocellular carcinoma: comparison with Immunoscore

https://doi.org/10.18632/oncotarget.5801

Cheng Sun, Jing Xu, Jiaxi Song, ChaoQun Liu, Jinyu Wang, Chenchun Weng, Haoyu Sun, Haiming Wei, Weihua Xiao, Rui Sun, and Zhigang Tian
35602-35615
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

First description of a sporadic breast cancer in a woman with BRCA1 germline mutation

https://doi.org/10.18632/oncotarget.5348

Elsa Curtit, Vanessa Benhamo, Nadège Gruel, Tatiana Popova, Elodie Manie, Paul Cottu, Odette Mariani, Dominique Stoppa-Lyonnet, Xavier Pivot, Marc-Henri Stern, and Anne Vincent-Salomon
35616-35624
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous Gquadruplexes and sparking a DNA damage response at the telomere region

https://doi.org/10.18632/oncotarget.5521

Yun-Xia Xiong, Hua-Fei Su, Peng Lv, Yan Ma, Shi-Ke Wang, Hui Miao, Hui-Yun Liu, Jia-Heng Tan, Tian-Miao Ou, Lian-Quan Gu, and Zhi-Shu Huang
35625-35635
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Retrograde TrkAIII transport from ERGIC to ER: a relocalisation mechanism for oncogenic activity

https://doi.org/10.18632/oncotarget.5802

Antonietta Rosella Farina, Lucia Cappabianca, Pierdomenico Ruggeri, Luciana Gneo, Rita Maccarone, and Andrew Reay Mackay
35636-35651
Abstract  |  PDF  |  Full Text  |  How to cite

The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells

https://doi.org/10.18632/oncotarget.5363

Diana Spiegelberg, Adrian Dascalu, Anja C. Mortensen, Andris Abramenkovs, Gamze Kuku, Marika Nestor, and Bo Stenerlöw
35652-35666
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting ERK1/2bim signaling cascades by BH3mimetic ABT737 as an alternative therapeutic strategy for oral cancer

https://doi.org/10.18632/oncotarget.5523

Ji-Ae Shin, Lee-Han Kim, Sook-Jeong Lee, Joseph H. Jeong, Ji-Youn Jung, Hae Nim Lee, In-Sun Hong, and Sung-Dae Cho
35667-35683
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression profile of long noncoding RNAs in pancreatic cancer and their clinical significance as biomarkers

https://doi.org/10.18632/oncotarget.5533

Yingxue Wang, Zhihua Li, Shangyou Zheng, Yu Zhou, Lei Zhao, Huilin Ye, Xiaohui Zhao, Wenchao Gao, Zhiqiang Fu, Quanbo Zhou, Yimin Liu, and Rufu Chen
35684-35698
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The tissue dependent interactions between p53 and Bcl2 in vivo

https://doi.org/10.18632/oncotarget.5372

Xin Li, Xiao Miao, Hongshen Wang, Zhixiang Xu, and Bin Li
35699-35709
Abstract  |  PDF  |  Full Text  |  How to cite

MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators

https://doi.org/10.18632/oncotarget.5958

Emeli M. Nilsson, Kristian B. Laursen, Jonathan Whitchurch, Andrew McWilliam, Niels Ødum, Jenny L. Persson, David M. Heery, Lorraine J. Gudas, and Nigel P. Mongan
35710-35725
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Detection of canonical AtoG editing events at 3’ UTRs and microRNA target sites in human lungs using nextgeneration sequencing

https://doi.org/10.18632/oncotarget.6132

Ramani Soundararajan, Timothy M. Stearns, Anthony J. Griswold, Arpit Mehta, Alexander Czachor, Jutaro Fukumoto, Richard F. Lockey, Benjamin L. King, and Narasaiah Kolliputi
35726-35736
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serine protease inhibitor Kazal type 1 SPINK1 drives proliferation and anoikis resistance in a subset of ovarian cancers

https://doi.org/10.18632/oncotarget.5927

Christine Mehner, Ann L. Oberg, Kimberly R. Kalli, Aziza Nassar, Alexandra Hockla, Devon Pendlebury, Magdalena A. Cichon, Krista M. Goergen, Matthew J. Maurer, Ellen L. Goode, Gary L. Keeney, Aminah Jatoi, Miklós Sahin-Tóth, John A. Copland, Derek C. Radisky, and Evette S. Radisky
35737-35754
Abstract  |  PDF  |  Full Text  |  How to cite

Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition

https://doi.org/10.18632/oncotarget.5928

John Paul Shen, Rohith Srivas, Andrew Gross, Jianfeng Li, Eric J. Jaehnig, Su Ming Sun, Ana Bojorquez-Gomez, Katherine Licon, Vignesh Sivaganesh, Jia L. Xu, Kristin Klepper, Huwate Yeerna, Daniel Pekin, Chu Ping Qiu, Haico van Attikum, Robert W. Sobol, and Trey Ideker
35755-35769
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Natural killer cells facilitate PRAMEspecific Tcell reactivity against neuroblastoma

https://doi.org/10.18632/oncotarget.5657

Lotte Spel, Jaap-Jan Boelens, Dirk M. van der Steen, Nina J.G. Blokland, Max M. van Noesel, Jan J. Molenaar, Mirjam H.M. Heemskerk, Marianne Boes, and Stefan Nierkens
35770-35781
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bone marrow macrophages support prostate cancer growth in bone

https://doi.org/10.18632/oncotarget.6042

Fabiana N. Soki, Sun Wook Cho, Yeo Won Kim, Jacqueline D. Jones, Serk In Park, Amy J. Koh, Payam Entezami, Stephanie Daignault-Newton, Kenneth J. Pienta, Hernan Roca, and Laurie K. McCauley
35782-35796
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of novel in vivo active Chk1 inhibitors utilizing structure guided drug design

https://doi.org/10.18632/oncotarget.5929

Andrew J. Massey, Stephen Stokes, Helen Browne, Nicolas Foloppe, Andreá Fiumana, Simon Scrace, Mandy Fallowfield, Simon Bedford, Paul Webb, Lisa Baker, Mark Christie, Martin J. Drysdale, and Mike Wood
35797-35812
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High expression of CTHRC1 promotes EMT of epithelial ovarian cancer EOC and is associated with poor prognosis

https://doi.org/10.18632/oncotarget.5358

Minzhi Hou, Zhiqiang Cheng, Hongwei Shen, Shanyang He, Yang Li, Yunping Pan, Chongjin Feng, Xinlin Chen, Yang Zhang, Millicent Lin, Liantang Wang, and Zunfu Ke
35813-35829
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Kruppellike factor 2 suppresses mammary carcinoma growth by regulating retinoic acid signaling

https://doi.org/10.18632/oncotarget.5767

Wei Zhang, Liraz Levi, Pallab Banerjee, Mukesh Jain, and Noa Noy
35830-35842
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of glutathione Stransferase T1 and M1 polymorphisms with prostate cancer susceptibility in populations of Asian descent: a metaanalysis

https://doi.org/10.18632/oncotarget.5346

Da-Long Cao, Ding-Wei Ye, Bo Dai, Hai-Liang Zhang, Yi-Jun Shen, Yao Zhu, Yi-Ping Zhu, Guo-Hai Shi, Chun-Guang Ma, Wen-Jun Xiao, Xiao-Jian Qin, and Guo-Wen Lin
35843-35850
Abstract  |  PDF  |  Full Text  |  How to cite

MAGI3 negatively regulates Wnt/βcatenin signaling and suppresses malignant phenotypes of glioma cells

https://doi.org/10.18632/oncotarget.5323

Qian Ma, Ying Yang, Duiping Feng, Shuai Zheng, Ran Meng, Pengyan Fa, Chunjuan Zhao, Hua Liu, Ran Song, Tao Tao, Longyan Yang, Jie Dai, Songlin Wang, Wen G. Jiang, and Junqi He
35851-35865
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mechanisms of dihydrotestosterone action on resveratrolinduced antiproliferation in breast cancer cells with different ERα status

https://doi.org/10.18632/oncotarget.5482

Yu-Tang Chin, Sheng-Huei Yang, Tung-Cheng Chang, Chun A. Changou, Hsuan-Yu Lai, Earl Fu, Wei-Chun HuangFu, Paul J. Davis, Hung-Yun Lin, and Leroy F. Liu
35866-35879
Abstract  |  PDF  |  Full Text  |  How to cite

Loss of p27Kip1 promotes metaplasia in the pancreas via the regulation of Sox9 expression

https://doi.org/10.18632/oncotarget.5770

Pauline Jeannot, Caroline Callot, Romain Baer, Nicolas Duquesnes, Carmen Guerra, Julie Guillermet-Guibert, Oriol Bachs, and Arnaud Besson
35880-35892
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The potent tumor suppressor miR497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L

https://doi.org/10.18632/oncotarget.5651

Shumin Wang, Yingxi Mo, Kaoru Midorikawa, Zhe Zhang, Guangwu Huang, Ning Ma, Weilin Zhao, Yusuke Hiraku, Shinji Oikawa, and Mariko Murata
35893-35907
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Blockade of telomerase reverse transcriptase enhances chemosensitivity in head and neck cancers through inhibition of AKT/ERK signaling pathways

https://doi.org/10.18632/oncotarget.5468

Tengda Zhao, Fengchun Hu, Xingguang Liu, and Qian Tao
35908-35921
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Frequent DPH3 promoter mutations in skin cancers

https://doi.org/10.18632/oncotarget.5771

Evgeniya Denisova, Barbara Heidenreich, Eduardo Nagore, P. Sivaramakrishna Rachakonda, Ismail Hosen, Ivana Akrap, Víctor Traves, Zaida García-Casado, José Antonio López-Guerrero, Celia Requena, Onofre Sanmartin, Carlos Serra-Guillén, Beatriz Llombart, Carlos Guillén, Jose Ferrando, Enrique Gimeno, Alfred Nordheim, Kari Hemminki, and Rajiv Kumar
35922-35930
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and βcatenin signaling

https://doi.org/10.18632/oncotarget.5933

Neha Woods, Jose Trevino, Domenico Coppola, Srikumar Chellappan, Shengyu Yang, and Jaya Padmanabhan
35931-35948
Abstract  |  PDF  |  Full Text  |  How to cite

Hippo transducer TAZ promotes epithelial mesenchymal transition and supports pancreatic cancer progression

https://doi.org/10.18632/oncotarget.5772

Dacheng Xie, Jiujie Cui, Tian Xia, Zhiliang Jia, Liang Wang, Wenfei Wei, Anna Zhu, Yong Gao, Keping Xie, and Ming Quan
35949-35963
Abstract  |  PDF  |  Full Text  |  How to cite

Dietary NiCl2 causes G2/M cell cycle arrest in the broiler’s kidney

https://doi.org/10.18632/oncotarget.5934

Hongrui Guo, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Bangyuan Wu, Kejie Chen, and Jie Deng
35964-35977
Abstract  |  PDF  |  Full Text  |  How to cite

miR573 inhibits prostate cancer metastasis by regulating epithelialmesenchymal transition

https://doi.org/10.18632/oncotarget.5427

Lin Wang, Guanhua Song, Weiwei Tan, Mei Qi, Lili Zhang, Jonathan Chan, Jindan Yu, Jinxiang Han, and Bo Han
35978-35990
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Molecular mechanisms underlying the antitumor activity of ENhydroxy314methoxyphenylsulfonyl1234tetrahydroquinolin6ylacrylamide in human colorectal cancer cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.5475

Chun-Han Chen, Chia-Hwa Lee, Jing-Ping Liou, Che-Ming Teng, and Shiow-Lin Pan
35991-36002
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The chimeric antibody chLpMab7 targeting human podoplanin suppresses pulmonary metastasis via ADCC and CDC rather than via its neutralizing activity

https://doi.org/10.18632/oncotarget.5339

Yukinari Kato, Akiko Kunita, Shinji Abe, Satoshi Ogasawara, Yuki Fujii, Hiroharu Oki, Masashi Fukayama, Yasuhiko Nishioka, and Mika K. Kaneko
36003-36018
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Active YAP promotes pancreatic cancer cell motility invasion and tumorigenesis in a mitotic phosphorylationdependent manner through LPAR3

https://doi.org/10.18632/oncotarget.5935

Shuping Yang, Lin Zhang, Vinee Purohit, Surendra K. Shukla, Xingcheng Chen, Fang Yu, Kai Fu, Yuanhong Chen, Joyce Solheim, Pankaj K. Singh, Wei Song, and Jixin Dong
36019-36031
Abstract  |  PDF  |  Full Text  |  How to cite

CD4+ T cells play a crucial role for lenalidomide in vivo antitumor activity in murine multiple myeloma

https://doi.org/10.18632/oncotarget.5506

Liang Zhang, Enguang Bi, Sungyoul Hong, Jianfei Qian, Chengyun Zheng, Michael Wang, and Qing Yi
36032-36040
Abstract  |  PDF  |  Full Text  |  How to cite

Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway

https://doi.org/10.18632/oncotarget.5936

Rajmohan Murali, Raghu Chandramohan, Inga Möller, Simone L. Scholz, Michael Berger, Kety Huberman, Agnes Viale, Mono Pirun, Nicholas D. Socci, Nancy Bouvier, Sebastian Bauer, Monika Artl, Bastian Schilling, Tobias Schimming, Antje Sucker, Benjamin Schwindenhammer, Florian Grabellus, Michael R. Speicher, Jörg Schaller, Uwe Hillen, Dirk Schadendorf, Thomas Mentzel, Donavan T. Cheng, Thomas Wiesner, and Klaus G. Griewank
36041-36052
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer

https://doi.org/10.18632/oncotarget.5937

Erin E. Witalison, Xiangli Cui, Corey P. Causey, Paul R. Thompson, and Lorne J. Hofseth
36053-36062
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Septin cooperation with tubulin polyglutamylation contributes to cancer cell adaptation to taxanes

https://doi.org/10.18632/oncotarget.5373

Laurence Froidevaux-Klipfel, Benjamin Targa, Isabelle Cantaloube, Hayat Ahmed-Zaïd, Christian Poüs, and Anita Baillet
36063-36080
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dietary fatty acids intake and endometrial cancer risk: a doseresponse metaanalysis of epidemiological studies

https://doi.org/10.18632/oncotarget.5555

Qi-Jun Wu, Ting-Ting Gong, and Ya-Zhu Wang
36081-36097
Abstract  |  PDF  |  Full Text  |  How to cite

Transgenerational inheritance of enhanced susceptibility to radiationinduced medulloblastoma in newborn Ptch1+/− mice after paternal irradiation

https://doi.org/10.18632/oncotarget.5553

Lorena Paris, Paola Giardullo, Simona Leonardi, Barbara Tanno, Roberta Meschini, Eugenia Cordelli, Barbara Benassi, Maria Grazia Longobardi, Alberto Izzotti, Alessandra Pulliero, Mariateresa Mancuso, and Francesca Pacchierotti
36098-36112
Abstract  |  PDF  |  Full Text  |  How to cite

Pharmacological inhibition of BclxL sensitizes osteosarcoma to doxorubicin

https://doi.org/10.18632/oncotarget.5333

Zuzanna Baranski, Yvonne de Jong, Trayana Ilkova, Elisabeth F.P. Peterse, Anne-Marie Cleton-Jansen, Bob van de Water, Pancras C.W. Hogendoorn, Judith V.M.G. Bovée, and Erik H.J. Danen
36113-36125
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The effective bioengineering method of implantation decellularized renal extracellular matrix scaffolds

https://doi.org/10.18632/oncotarget.5304

Yong Guan, Shuangde Liu, Chao Sun, Guanghui Cheng, Feng Kong, Yun Luan, Xiaoshuai Xie, Shengtian Zhao, Denglu Zhang, Jue Wang, Kailin Li, and Yuqiang Liu
36126-36138
Abstract  |  PDF  |  Full Text  |  How to cite

Sulfonamide derivative targeting carbonic anhydrase IX as a nuclear imaging probe for colorectal cancer detection in vivo

https://doi.org/10.18632/oncotarget.5684

Siao-Syun Guan, Chun-Chia Cheng, Ai-Sheng Ho, Chia-Chi Wang, Tsai-Yueh Luo, Tse-Zung Liao, Jungshan Chang, Cheng-Tien Wu, and Shing-Hwa Liu
36139-36155
Abstract  |  PDF  |  Full Text  |  How to cite

Opposite regulation of MDM2 and MDMX expression in acquisition of mesenchymal phenotype in benign and cancer cells

https://doi.org/10.18632/oncotarget.5392

Eva Slabáková, Gvantsa Kharaishvili, Monika Smějová, Zuzana Pernicová, Tereza Suchánková, Ján Remšík, Stanislav Lerch, Nicol Straková, Jan Bouchal, Milan Král, Zoran Culig, Alois Kozubík, and Karel Souček
36156-36171
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial βF1ATPase subunit in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.5459

Christian U. Huebbers, Alexander C. Adam, Simon F. Preuss, Theresa Schiffer, Sarah Schilder, Orlando Guntinas-Lichius, Matthias Schmidt, Jens P. Klussmann, and Rudolf J. Wiesner
36172-36184
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Functional and molecular characterization of cancer stemlike cells in bladder cancer: a potential signature for muscleinvasive tumors

https://doi.org/10.18632/oncotarget.5517

Margarida Ferreira-Teixeira, Belmiro Parada, Paulo Rodrigues-Santos, Vera Alves, José S. Ramalho, Francisco Caramelo, Vitor Sousa, Flávio Reis, and Célia M. Gomes
36185-36201
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sensitization of multidrugresistant human cancer cells to Hsp90 inhibitors by downregulation of SIRT1

https://doi.org/10.18632/oncotarget.5343

Hak-Bong Kim, Su-Hoon Lee, Jee-Hyun Um, Won Keun Oh, Dong-Wan Kim, Chi-Dug Kang, and Sun-Hee Kim
36202-36218
Abstract  |  PDF  |  Full Text  |  How to cite

HER2 as a novel therapeutic target for cervical cancer

https://doi.org/10.18632/oncotarget.5283

Doo-Yi Oh, Seokhwi Kim, Yoon-La Choi, Young Jae Cho, Ensel Oh, Jung-Joo Choi, Kyungsoo Jung, Ji-Young Song, Suzie E. Ahn, Byoung-Gie Kim, Duk-Soo Bae, Woong-Yang Park, Jeong-Won Lee, and Sangyong Song
36219-36230
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR25 promotes hepatocellular carcinoma cell growth migration and invasion by inhibiting RhoGDI1

https://doi.org/10.18632/oncotarget.4740

Congren Wang, Xuejin Wang, Zijian Su, Hongjiang Fei, Xiaoyu Liu, and Qunxiong Pan
36231-36244
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Axitinib induces DNA damage response leading to senescence mitotic catastrophe and increased NK cell recognition in human renal carcinoma cells

https://doi.org/10.18632/oncotarget.5768

Maria Beatrice Morelli, Consuelo Amantini, Matteo Santoni, Alessandra Soriani, Massimo Nabissi, Claudio Cardinali, Angela Santoni, and Giorgio Santoni
36245-36259
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Focused ultrasound enhanced molecular imaging and gene therapy for multifusion reporter gene in gliomabearing rat model

https://doi.org/10.18632/oncotarget.5389

Feng-Yi Yang, Wen-Yuan Chang, Wei-Ting Lin, Jeng-Jong Hwang, Yi-Chun Chien, Hsin-Ell Wang, and Min-Lan Tsai
36260-36268
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic polymorphisms associated with increased risk of developing chronic myelogenous leukemia

https://doi.org/10.18632/oncotarget.5915

Heriberto Bruzzoni-Giovanelli, Juan R. González, François Sigaux, Bruno O. Villoutreix, Jean Michel Cayuela, Joëlle Guilhot, Claude Preudhomme, François Guilhot, Jean-Luc Poyet, and Philippe Rousselot
36269-36277
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

GIT1 promotes lung cancer cell metastasis through modulating Rac1/Cdc42 activity and is associated with poor prognosis

https://doi.org/10.18632/oncotarget.5531

Jeng-Shou Chang, Chia-Yi Su, Wen-Hsuan Yu, Wei-Jiunn Lee, Yu-Peng Liu, Tsung-Ching Lai, Yi-Hua Jan, Yi-Fang Yang, Chia-Ning Shen, Jin-Yuh Shew, Jean Lu, Chih-Jen Yang, Ming-Shyan Huang, Pei-Jung Lu, Yuan-Feng Lin, Min-Liang Kuo, Kuo-Tai Hua, and Michael Hsiao
36278-36291
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pharmacologic regulation of AMPK in breast cancer affects cytoskeletal properties involved with microtentacle formation and reattachment

https://doi.org/10.18632/oncotarget.5345

Kristi R. Chakrabarti, Rebecca A. Whipple, Amanda E. Boggs, Lindsay K. Hessler, Lekhana Bhandary, Michele I. Vitolo, Keyata Thompson, and Stuart S. Martin
36292-36307
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

On representing the prognostic value of continuous gene expression biomarkers with the restricted mean survival curve

https://doi.org/10.18632/oncotarget.6121

Kevin H. Eng, Emily Schiller, and Kayla Morrel
36308-36318
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of testicular embryonal carcinoma cell tumorigenicity by peroxisome proliferatoractivated receptorβ/δ and retinoic acid receptordependent mechanisms

https://doi.org/10.18632/oncotarget.5415

Pei-Li Yao, Li Ping Chen, Tomasz P. Dobrzański, Dylan A. Phillips, Bokai Zhu, Boo-Hyon Kang, Frank J. Gonzalez, and Jeffrey M. Peters
36319-36337
Abstract  |  PDF  |  Full Text  |  How to cite

Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1

https://doi.org/10.18632/oncotarget.5537

Zongwei Gao, Qingjuan Shang, Zhaoyun Liu, Chun Deng, and Chunbao Guo
36338-36353
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Quinacrine promotes autophagic cell death and chemosensitivity in ovarian cancer and attenuates tumor growth

https://doi.org/10.18632/oncotarget.5632

Ashwani Khurana, Debarshi Roy, Eleftheria Kalogera, Susmita Mondal, Xuyang Wen, Xiaoping He, Sean Dowdy, and Viji Shridhar
36354-36369
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Regulation of SOX10 stability via ubiquitinationmediated degradation by Fbxw7α modulates melanoma cell migration

https://doi.org/10.18632/oncotarget.5639

Xiao-Bin Lv, Wei Wu, Xiaofeng Tang, Yanqing Wu, Yinghua Zhu, Yujie Liu, Xiuying Cui, Junjun Chu, Pengnan Hu, Jingjing Li, Qiannan Guo, Zeming Cai, Juan Wu, Kaishun Hu, and Nengyong Ouyang
36370-36382
Abstract  |  PDF  |  Full Text  |  How to cite

SP600125 has a remarkable anticancer potential against undifferentiated thyroid cancer through selective action on ROCK and p53 pathways

https://doi.org/10.18632/oncotarget.5799

Elisa Stellaria Grassi, Valeria Vezzoli, Irene Negri, Árpád Lábadi, Laura Fugazzola, Giovanni Vitale, and Luca Persani
36383-36399
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

mTOR and MEK1/2 inhibition differentially modulate tumor growth and the immune microenvironment in syngeneic models of oral cavity cancer

https://doi.org/10.18632/oncotarget.5063

Harrison Cash, Sujay Shah, Ellen Moore, Andria Caruso, Ravindra Uppaluri, Carter Van Waes, and Clint Allen
36400-36417
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phospholipase C gamma 1 PLCG1 R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma

https://doi.org/10.18632/oncotarget.5503

Hans Prenen, Dominiek Smeets, Massimiliano Mazzone, Diether Lambrechts, Xavier Sagaert, Raf Sciot, and Maria Debiec-Rychter
36418-36425
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cytoskeletal protein Flightless I inhibits apoptosis enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression

https://doi.org/10.18632/oncotarget.5536

Zlatko Kopecki, Gink N. Yang, Jessica E. Jackson, Elizabeth L. Melville, Matthew P. Caley, Dedee F. Murrell, Ian A. Darby, Edel A. O’Toole, Michael S. Samuel, and Allison J. Cowin
36426-36440
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metformin prevents cancer metastasis by inhibiting M2like polarization of tumor associated macrophages

https://doi.org/10.18632/oncotarget.5541

Ling Ding, Guikai Liang, Zhangting Yao, Jieqiong Zhang, Ruiyang Liu, Huihui Chen, Yulu Zhou, Honghai Wu, Bo Yang, and Qiaojun He
36441-36455
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TIC10/ONC201 synergizes with Bcl2/BclxL inhibition in glioblastoma by suppression of Mcl1 and its binding partners in vitro and in vivo

https://doi.org/10.18632/oncotarget.5505

Georg Karpel-Massler, Maïmouna Bâ, Chang Shu, Marc-Eric Halatsch, M.-Andrew Westhoff, Jeffrey N. Bruce, Peter Canoll, and Markus D. Siegelin
36456-36471
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitotic entry: Nongenetic heterogeneity exposes the requirement for Plk1

https://doi.org/10.18632/oncotarget.5507

Claire F. Aspinall, Daniella Zheleva, Anthony Tighe, and Stephen S. Taylor
36472-36488
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

URGCP promotes nonsmall cell lung cancer invasiveness by activating the NFκBMMP9 pathway

https://doi.org/10.18632/oncotarget.5351

Junchao Cai, Rong Li, Xiaonan Xu, Le Zhang, Shanshan Wu, Tianyou Yang, Lishan Fang, Jueheng Wu, Xun Zhu, Mengfeng Li, and Yongbo Huang
36489-36504
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Auranofin induces apoptosis by ROSmediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancer

https://doi.org/10.18632/oncotarget.5364

Peng Zou, Minxiao Chen, Jiansong Ji, Weiqian Chen, Xi Chen, Shilong Ying, Junru Zhang, Ziheng Zhang, Zhiguo Liu, Shulin Yang, and Guang Liang
36505-36521
Abstract  |  PDF  |  Full Text  |  How to cite

RD3 loss dictates highrisk aggressive neuroblastoma and poor clinical outcomes

https://doi.org/10.18632/oncotarget.5204

Faizan H. Khan, Vijayabaskar Pandian, Satish Kumar Ramraj, Sheeja Aravindan, Mohan Natarajan, Seifollah Azadi, Terence S. Herman, and Natarajan Aravindan
36522-36534
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Chitinase 3like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitisassociated cancer by regulating S100A9

https://doi.org/10.18632/oncotarget.5440

Daren Low, Renuka Subramaniam, Li Lin, Tomoki Aomatsu, Atsushi Mizoguchi, Aylwin Ng, Arianna K. DeGruttola, Chun Geun Lee, Jack A. Elias, Akira Andoh, Mari Mino-Kenudson, and Emiko Mizoguchi
36535-36550
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Deubiquitinating enzyme USP37 regulating oncogenic function of 1433γ

https://doi.org/10.18632/oncotarget.5336

Jin-Ock Kim, So-Ra Kim, Key-Hwan Lim, Jun-Hyun Kim, Brijesh Ajjappala, Hey-Jin Lee, Jee-In Choi, and Kwang-Hyun Baek
36551-36576
Abstract  |  PDF  |  Full Text  |  How to cite

Good syndrome presenting with CD8+ TCell large granular lymphocyte leukemia

https://doi.org/10.18632/oncotarget.5369

Caroline Caperton, Sudhanshu Agrawal, and Sudhir Gupta
36577-36586
Abstract  |  PDF  |  Full Text  |  How to cite

Novel RNA variants in colorectal cancers

https://doi.org/10.18632/oncotarget.5500

Andreas M. Hoff, Bjarne Johannessen, Sharmini Alagaratnam, Sen Zhao, Torfinn Nome, Marthe Løvf, Anne C. Bakken, Merete Hektoen, Anita Sveen, Ragnhild A. Lothe, and Rolf I. Skotheim
36587-36602
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of drugs as single agents or in combination to prevent carcinoma dissemination in a microfluidic 3D environment

https://doi.org/10.18632/oncotarget.5464

Jing Bai, Ting-Yuan Tu, Choong Kim, Jean Paul Thiery, and Roger D. Kamm
36603-36614
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of denticleless E3 ubiquitin protein ligase homolog DTL is related to poor outcome in gastric carcinoma

https://doi.org/10.18632/oncotarget.5620

Hiroki Kobayashi, Shuhei Komatsu, Daisuke Ichikawa, Tsutomu Kawaguchi, Shoji Hirajima, Mahito Miyamae, Wataru Okajima, Takuma Ohashi, Toshiyuki Kosuga, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto, Hitoshi Tsuda, and Eigo Otsuji
36615-36624
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Application of functional vincristine plus dasatinib liposomes to deletion of vasculogenic mimicry channels in triplenegative breast cancer

https://doi.org/10.18632/oncotarget.5382

Fan Zeng, Rui-Jun Ju, Lei Liu, Hong-Jun Xie, Li-Min Mu, Yao Zhao, Yan Yan, Ying-Jie Hu, Jia-Shuan Wu, and Wan-Liang Lu
36625-36642
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of high risk anaplastic gliomas by a diagnostic and prognostic signature derived from mRNA expression profiling

https://doi.org/10.18632/oncotarget.5421

Chuan-Bao Zhang, Ping Zhu, Pei Yang, Jin-Quan Cai, Zhi-Liang Wang, Qing-Bin Li, Zhao-Shi Bao, Wei Zhang, and Tao Jiang
36643-36651
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genome and transcriptome delineation of two major oncogenic pathways governing invasive ductal breast cancer development

https://doi.org/10.18632/oncotarget.5543

Luay Aswad, Surya Pavan Yenamandra, Ghim Siong Ow, Oleg Grinchuk, Anna V. Ivshina, and Vladimir A. Kuznetsov
36652-36674
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

microRNA7 as a tumor suppressor and novel therapeutic for adrenocortical carcinoma

https://doi.org/10.18632/oncotarget.5383

Anthony R Glover, Jing Ting Zhao, Anthony J Gill, Jocelyn Weiss, Nancy Mugridge, Edward Kim, Alex L Feeney, Julian C Ip, Glen Reid, Stephen Clarke, Patsy S H Soon, Bruce G Robinson, Himanshu Brahmbhatt, Jennifer A. MacDiarmid, and Stan B Sidhu
36675-36688
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PRIMA1met APR246 inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms

https://doi.org/10.18632/oncotarget.5385

Xiao-Lan Li, Jianbiao Zhou, Zit-Liang Chan, Jing-Yuan Chooi, Zhi-Rong Chen, and Wee-Joo Chng
36689-36699
Abstract  |  PDF  |  Full Text  |  How to cite

INSM1 increases Nmyc stability and oncogenesis via a positivefeedback loop in neuroblastoma

https://doi.org/10.18632/oncotarget.5485

Chiachen Chen, Mary B. Breslin, and Michael S. Lan
36700-36712
Abstract  |  PDF  |  Full Text  |  How to cite

Hes1 triggers epithelialmesenchymal transition EMTlike cellular marker alterations and promotes invasion and metastasis of nasopharyngeal carcinoma by activating the PTEN/AKT pathway

https://doi.org/10.18632/oncotarget.5457

Sheng-Chun Wang, Xiao-Lin Lin, Hui-Yan Wang, Yu-Juan Qin, Lin Chen, Jing Li, Jun-Shuang Jia, Hong-Fen Shen, Sheng Yang, Rao-Ying Xie, Fang Wei, Fei Gao, Xiao-Xiang Rong, Jie Yang, Wen-Tao Zhao, Ting-Ting Zhang, Jun-Wen Shi, Kai-Tai Yao, Wei-Ren Luo, Yan Sun, and Dong Xiao
36713-36730
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The axon guidance molecule semaphorin 3F is a negative regulator of tumor progression and proliferation in ileal neuroendocrine tumors

https://doi.org/10.18632/oncotarget.5481

Julien Bollard, Patrick Massoma, Cécile Vercherat, Martine Blanc, Florian Lepinasse, Nicolas Gadot, Christophe Couderc, Gilles Poncet, Thomas Walter, Marie-Odile Joly, Valérie Hervieu, Jean-Yves Scoazec, and Colette Roche
36731-36745
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Adiponectin promotes VEGFAdependent angiogenesis in human chondrosarcoma through PI3K Akt mTOR and HIFα pathway

https://doi.org/10.18632/oncotarget.5479

Hsiang-Ping Lee, Chih-Yang Lin, Jhao-Sheng Shih, Yi-Chin Fong, Shih-Wei Wang, Te-Mao Li, and Chih-Hsin Tang
36746-36761
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD44mediated activation of α5β1integrin cortactin and paxillin signaling underpins adhesion of basallike breast cancer cells to endothelium and fibronectinenriched matrices

https://doi.org/10.18632/oncotarget.5461

Suzanne McFarlane, Cheryl McFarlane, Nicola Montgomery, Ashleigh Hill, and David J.J. Waugh
36762-36773
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells

https://doi.org/10.18632/oncotarget.4908

Jelena Ivanovska, Inti Zlobec, Stefan Forster, Eva Karamitopoulou, Heather Dawson, Viktor Hendrik Koelzer, Abbas Agaimy, Fabian Garreis, Stephan Söder, William Laqua, Alessandro Lugli, Arndt Hartmann, Tilman T. Rau, and Regine Schneider-Stock
36774-36788
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome

https://doi.org/10.18632/oncotarget.5103

Sandeep C. Chaudhary, Xiuwei Tang, Aadithya Arumugam, Changzhao Li, Ritesh K. Srivastava, Zhiping Weng, Jianmin Xu, Xiao Zhang, Arianna L. Kim, Kristopher McKay, Craig A. Elmets, Levy Kopelovich, David R. Bickers, and Mohammad Athar
36789-36814
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Plasma miR200b in ovarian carcinoma patients: distinct pattern of pre/posttreatment variation compared to CA125 and potential for prediction of progressionfree survival

https://doi.org/10.18632/oncotarget.5766

Nikiforos-Ioannis Kapetanakis, Catherine Uzan, Anne-Sophie Jimenez-Pailhes, Sébastien Gouy, Enrica Bentivegna, Philippe Morice, Olivier Caron, Claire Gourzones-Dmitriev, Gwénaël Le Teuff, and Pierre Busson
36815-36824
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The timing of surgery after neoadjuvant radiotherapy influences tumor dissemination in a preclinical model

https://doi.org/10.18632/oncotarget.5931

Natacha Leroi, Nor Eddine Sounni, Eva Van Overmeire, Silvia Blacher, Raphael Marée, Jo Van Ginderachter, François Lallemand, Eric Lenaerts, Philippe Coucke, Agnès Noel, and Philippe Martinive
36825-36837
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hepatic resection alone versus in combination with pre and postoperative transarterial chemoembolization for the treatment of hepatocellular carcinoma: A systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.5426

Xingshun Qi, Lei Liu, Diya Wang, Hongyu Li, Chunping Su, and Xiaozhong Guo
36838-36859
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Isolated locoregional recurrence patterns of breast cancer after mastectomy and adjuvant systemic therapies in the contemporary era

https://doi.org/10.18632/oncotarget.5365

Jinli Ma, Rui Jiang, Lihua Fan, Xin Mei, Zhaozhi Yang, Xiaoli Yu, Xiaomao Guo, Zhen Zhang, and Zhimin Shao
36860-36869
Abstract  |  PDF  |  Full Text  |  How to cite

Clinicopathological and prognostic factors for longterm survival in Chinese patients with metastatic renal cell carcinoma treated with sorafenib: a singlecenter retrospective study

https://doi.org/10.18632/oncotarget.4874

Hai-Liang Zhang, Xiao-Jian Qin, Hong-Kai Wang, Wei-Jie Gu, Chun-Guang Ma, Guo-Hai Shi, Liang-Ping Zhou, and Ding-Wei Ye
36870-36883
Abstract  |  PDF  |  Full Text  |  How to cite

Risk factors short and long term outcome of anastomotic leaks in rectal cancer

https://doi.org/10.18632/oncotarget.5170

Olof Jannasch, Tim Klinge, Ronny Otto, Costanza Chiapponi, Andrej Udelnow, Hans Lippert, Christiane J. Bruns, and Pawel Mroczkowski
36884-36893
Abstract  |  PDF  |  Full Text  |  How to cite

Alterations of biomarker profiles after neoadjuvant chemotherapy in breast cancer: tumor heterogeneity should be taken into consideration

https://doi.org/10.18632/oncotarget.5050

Xingchen Zhou, Junyong Zhang, Haiqin Yun, Ranran Shi, Yan Wang, Wei Wang, Svetlana Bajalica Lagercrantz, and Kun Mu
36894-36902
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Resected pancreatic ductal adenocarcinomas with recurrence limited in lung have a significantly better prognosis than those with other recurrence patterns

https://doi.org/10.18632/oncotarget.5054

Tamna Wangjam, Zhe Zhang, Xian Chong Zhou, Laxmi Lyer, Farzana Faisal, Kevin C. Soares, Elliott Fishman, Ralph H. Hruban, Joseph M. Herman, Daniel Laheru, Matthew Weiss, Min Li, Ana De Jesus-Acosta, Christopher L. Wolfgang, and Lei Zheng
36903-36910
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognosis of patients with esophageal squamous cell carcinoma after esophagectomy using the log odds of positive lymph nodes

https://doi.org/10.18632/oncotarget.5366

San-Gang Wu, Jia-Yuan Sun, Li-Chao Yang, Juan Zhou, Feng-Yan Li, Qun Li, Huan-Xin Lin, Qin Lin, and Zhen-Yu He
36911-36922
Abstract  |  PDF  |  Full Text  |  How to cite

Errata

Erratum: Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome

https://doi.org/10.18632/oncotarget.6263

Damien A. Leach, Eleanor F. Need, Roxanne Toivanen, Andrew P. Trotta, Helen M. Palethorpe, David J. Tamblyn, Tina Kopsaftis, Georgina M. England, Eric Smith, Paul A. Drew, Carole B. Pinnock, Peng Lee, Jeff Holst, Gail P. Risbridger, Samarth Chopra, Donald B. DeFranco, Renea A. Taylor, and Grant Buchanan
36923
Erratum  |  PDF  |  How to cite


Copyright © 2026 Rapamycin Press LLC dba Impact Journals
Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
RAPAMYCIN PRESS ® is a registered trademark of Rapamycin Press LLC
By using our site you are giving us permission to use cookies. This website collects cookies to deliver a better user experience, and to analyze our website traffic and performance. Personal data is not collected.