VOLUME 8 (2017)
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About The Cover
The cover for issue 62 of Oncotarget features Supplementary Figure 4, "Histopathological analysis of liver and lung of mice injected with PBMCs, PBMCs and nTreg cells expanded in the presence of rapamycin alone or rapamycin (R) associated with vorinostat and azacytidin (RAV). Broken line circles surround lymphocytic infiltrates," from Miyara, et al.
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Table of Contents
Editorial
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| Targeting macrophages to treat intracranial aneurysm |
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https://doi.org/10.18632/oncotarget.21368
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| 104704-104705 |
Research Papers: Gerotarget (Focus on Aging)
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| Weight loss in the healthy elderly might be a noncognitive sign of preclinical Alzheimer’s disease |
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https://doi.org/10.18632/oncotarget.22218
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| 104706-104716 |
Research Papers
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| Rab coupling protein mediated endosomal recycling of Ncadherin influences cell motility |
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https://doi.org/10.18632/oncotarget.10513
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| 104717-104732 |
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| Combination of IL2 rapamycin DNA methyltransferase and histone deacetylase inhibitors for the expansion of human regulatory T cells |
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https://doi.org/10.18632/oncotarget.10914
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| 104733-104744 |
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| Discovery and evaluation of triple inhibitors of VEGFR2 TIE2 and EphB4 as antiangiogenic and anticancer agents |
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https://doi.org/10.18632/oncotarget.20065
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| 104745-104760 |
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| Molecular analyses of prostate tumors for diagnosis of malignancy on fineneedle aspiration biopsies |
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https://doi.org/10.18632/oncotarget.22289
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| 104761-104771 |
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| Tumorsuppressive effect of Sadenosylmethionine supplementation in a murine model of inflammationmediated hepatocarcinogenesis is dependent on treatment longevity |
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https://doi.org/10.18632/oncotarget.18300
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| 104772-104784 |
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| Clinicopathological features and prognosis of malignant peripheral nerve sheath tumor: a retrospective study of 159 cases from 1999 to 2016 |
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https://doi.org/10.18632/oncotarget.18975
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| 104785-104795 |
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| mRNA expression profiles obtained from microdissected pancreatic cancer cells can predict patient survival |
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https://doi.org/10.18632/oncotarget.20076
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| 104796-104805 |
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| Depression and its impact on healthrelated quality of life among Chinese inpatients with lung cancer |
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https://doi.org/10.18632/oncotarget.21001
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| 104806-104812 |
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| Lamin B2 binding to minichromosome maintenance complex component 7 promotes nonsmall cell lung carcinogenesis |
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https://doi.org/10.18632/oncotarget.20338
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| 104813-104830 |
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| Identification of novel gene expression signature in lung adenocarcinoma by using nextgeneration sequencing data and bioinformatics analysis |
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https://doi.org/10.18632/oncotarget.21022
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| 104831-104854 |
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| Doxycycline inhibits breast cancer EMT and metastasis through PAR1/NFκB/miR17/Ecadherin pathway |
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https://doi.org/10.18632/oncotarget.20418
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| 104855-104866 |
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| MicroRNA200a activates Nrf2 signaling to protect osteoblasts from dexamethasone |
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https://doi.org/10.18632/oncotarget.20452
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| 104867-104876 |
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| Dietary polyphenols influence antimetabolite agents: methotrexate 6mercaptopurine and 5fluorouracil in leukemia cell lines |
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https://doi.org/10.18632/oncotarget.20501
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| 104877-104893 |
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| A cJun Nterminal kinase inhibitor JNKIN8 sensitizes triple negative breast cancer cells to lapatinib |
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https://doi.org/10.18632/oncotarget.20581
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| 104894-104912 |
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| A primary tumor gene expression signature identifies a crucial role played by tumor stroma myofibroblasts in lymph node involvement in oral squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.20645
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| 104913-104927 |
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| A CARP1 functional mimetic loaded vitamin ETPGS micellar nanoformulation for inhibition of renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.20650
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| 104928-104945 |
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| Soluble chemokine CXC motif ligand 16 CXCL16 in urine as a novel biomarker candidate to identify high grade and muscle invasive urothelial carcinomas |
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https://doi.org/10.18632/oncotarget.20737
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| 104946-104959 |
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| The protective value of miR2045p for prognosis and its potential gene network in various malignancies: a comprehensive exploration based on RNAseq highthroughput data and bioinformatics |
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https://doi.org/10.18632/oncotarget.21950
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| 104960-104980 |
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| Parity improves antitumor immunity in breast cancer patients |
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https://doi.org/10.18632/oncotarget.20756
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| 104981-104991 |
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| Effects of trimetazidine on periprocedural microRNA21 expression by CD4+ T lymphocytes in patients with unstable angina pectoris |
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https://doi.org/10.18632/oncotarget.20975
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| 104992-104999 |
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| Fourmonth course of adjuvant dabrafenib in patients with surgically resected stage IIIC melanoma characterized by a BRAFV600E/K mutation |
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https://doi.org/10.18632/oncotarget.21072
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| 105000-105010 |
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| Relationship of tumor size with pathological and prognostic factors for hilar cholangiocarcinoma |
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https://doi.org/10.18632/oncotarget.22054
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| 105011-105019 |
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| Gene editing of the extra domain A positive fibronectin in various tumors amplified the effects of CRISPR/Cas system on the inhibition of tumor progression |
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https://doi.org/10.18632/oncotarget.21136
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| 105020-105036 |
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| Associations between TNFSF4 TNFSF8 and TNFSF15 and Behçet's disease but not VKH syndrome in Han Chinese |
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https://doi.org/10.18632/oncotarget.22064
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| 105037-105046 |
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| Synergistic effect of farnesyl transferase inhibitor lonafarnib combined with chemotherapeutic agents against the growth of hepatocellular carcinoma cells |
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https://doi.org/10.18632/oncotarget.22086
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| 105047-105060 |
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| AIO LQ0110: a randomized phase II trial comparing oral doxycycline versus local administration of erythromycin as preemptive treatment strategies of panitumumabmediated skin toxicity in patients with metastatic colorectal cancer |
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https://doi.org/10.18632/oncotarget.21249
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| 105061-105071 |
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| Targeted next generation sequencing in Chinese colorectal cancer patients guided antiEGFR treatment and facilitated precision cancer medicine |
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https://doi.org/10.18632/oncotarget.21349
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| 105072-105080 |
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| Eyes absent gene EYA1 is a pathogenic driver and a therapeutic target for melanoma |
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https://doi.org/10.18632/oncotarget.21352
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| 105081-105092 |
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| Intrapleural targeted therapies antiVEGF and antiEGFR in the model of malignant pleural effusion |
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https://doi.org/10.18632/oncotarget.21362
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| 105093-105102 |
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| Outcome of EGFRmutated NSCLC patients with METdriven resistance to EGFR tyrosine kinase inhibitors |
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https://doi.org/10.18632/oncotarget.21707
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| 105103-105114 |
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| Hepatitis B virus HBV X gene mutations and their association with liver disease progression in HBVinfected patients |
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https://doi.org/10.18632/oncotarget.22428
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| 105115-105125 |
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| Low density lipoprotein rosiglitazone chitosancalcium alginate/nanoparticles inhibition of human tenon’s fibroblasts activation and proliferation |
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https://doi.org/10.18632/oncotarget.21757
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| 105126-105136 |
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| Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ7 |
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https://doi.org/10.18632/oncotarget.21806
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| 105137-105154 |
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| GOLPH3: a novel biomarker that correlates with poor survival and resistance to chemotherapy in breast cancer |
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https://doi.org/10.18632/oncotarget.21927
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| 105155-105169 |
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| Roscovitine strongly enhances the effect of olaparib on radiosensitivity for HPV neg but not for HPV pos HNSCC cell lines |
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https://doi.org/10.18632/oncotarget.22005
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| 105170-105183 |
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| High visceral fat percentage is associated with poor outcome in endometrial cancer |
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https://doi.org/10.18632/oncotarget.21917
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| 105184-105195 |
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| Coordinated downregulation of Spinophilin and the catalytic subunits of PP1 PPP1CA/B/C contributes to a worse prognosis in lung cancer |
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https://doi.org/10.18632/oncotarget.22111
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| 105196-105210 |
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| A population pharmacokinetic model for individualised dosage regimens of vancomycin in Chinese neonates and young infants |
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https://doi.org/10.18632/oncotarget.22114
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| 105211-105221 |
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| Gene function analysis and underlying mechanism of esophagus cancer based on microarray gene expression profiling |
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https://doi.org/10.18632/oncotarget.22160
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| 105222-105237 |
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| CTHRC1 activates protumorigenic signaling pathways in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.22164
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| 105238-105250 |
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| Super enhancer associated RAI14 is a new potential biomarker in lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.22165
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| 105251-105261 |
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| Retinol dehydrogenase10 promotes development and progression of human glioma via the TWEAKNFκB axis |
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https://doi.org/10.18632/oncotarget.22166
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| 105262-105275 |
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| SPC24 promotes osteosarcoma progression by increasing EGFR/MAPK signaling |
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https://doi.org/10.18632/oncotarget.22167
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| 105276-105283 |
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| Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines mediated by NFκB p65 and EzH2 in colitisassociated cancer |
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https://doi.org/10.18632/oncotarget.22168
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| 105284-105298 |
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| Immunological landscape of consensus clusters in colorectal cancer |
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https://doi.org/10.18632/oncotarget.22169
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| 105299-105311 |
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| Functional polymorphisms in NR3C1 are associated with gastric cancer risk in Chinese population |
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https://doi.org/10.18632/oncotarget.22172
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| 105312-105319 |
|
| MicroRNA coexpression networks exhibit increased complexity in pancreatic ductal compared to Vater’s papilla adenocarcinoma |
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https://doi.org/10.18632/oncotarget.22184
|
| 105320-105339 |
|
| Agrin parasecreted by PDGFactivated human hepatic stellate cells promotes hepatocarcinogenesis in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.22186
|
| 105340-105355 |
|
| Investigation of RIP140 and LCoR as independent markers for poor prognosis in cervical cancer |
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https://doi.org/10.18632/oncotarget.22187
|
| 105356-105371 |
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| Sensitization of lung cancer cells by altered dimerization of HSP27 |
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https://doi.org/10.18632/oncotarget.22192
|
| 105372-105382 |
|
| Mek activity is required for ErbB2 expression in breast cancer cells detached from the extracellular matrix |
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https://doi.org/10.18632/oncotarget.22194
|
| 105383-105396 |
|
| CD20 expression substratifies standardrisk patients with B cell precursor acute lymphoblastic leukemia |
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https://doi.org/10.18632/oncotarget.22207
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| 105397-105406 |
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| Genetic variations of NTCP are associated with susceptibility to HBV infection and related hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.22211
|
| 105407-105424 |
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| Use of autoantibodies against tumorassociated antigens as serum biomarkers for primary screening of cervical cancer |
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https://doi.org/10.18632/oncotarget.22231
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| 105425-105439 |
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| Nuclear membranelocalised NOX4D generates prosurvival ROS in FLT3ITDexpressing AML |
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https://doi.org/10.18632/oncotarget.22241
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| 105440-105457 |
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| Predicting castrationresistant prostate cancer after combined androgen blockade |
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https://doi.org/10.18632/oncotarget.22246
|
| 105458-105462 |
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| Decreased incidence of glaucoma in children with asthma using inhaled corticosteroid: a cohort study |
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https://doi.org/10.18632/oncotarget.22252
|
| 105463-105471 |
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| Role of VEGFA gene polymorphisms in colorectal cancer patients who treated with bevacizumab |
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https://doi.org/10.18632/oncotarget.22295
|
| 105472-105478 |
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| Characterization of the efficacies of osimertinib and nazartinib against cells expressing clinically relevant epidermal growth factor receptor mutations |
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https://doi.org/10.18632/oncotarget.22297
|
| 105479-105491 |
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| A molecular signature of lung cancer: potential biomarkers for adenocarcinoma and squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.22298
|
| 105492-105509 |
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| Reactive oxygen species levels control NFκB activation by low dose deferasirox in erythroid progenitors of low risk myelodysplastic syndromes |
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https://doi.org/10.18632/oncotarget.22299
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| 105510-105524 |
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| SphK2 overexpression promotes osteosarcoma cell growth |
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https://doi.org/10.18632/oncotarget.22314
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| 105525-105535 |
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| Metformin alleviates nickelinduced autophagy and apoptosis via inhibition of hexokinase2 activating lipocalin2 in human bronchial epithelial cells |
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https://doi.org/10.18632/oncotarget.22317
|
| 105536-105552 |
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| Identification of a three miRNA signature as a novel potential prognostic biomarker in patients with bladder cancer |
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https://doi.org/10.18632/oncotarget.22318
|
| 105553-105560 |
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| Baicalein suppresses the androgen receptor ARmediated prostate cancer progression via inhibiting the AR NC dimerization and ARcoactivators interaction |
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https://doi.org/10.18632/oncotarget.22319
|
| 105561-105573 |
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| The meta and bioinformatics analysis of fascin expression in gastric cancer: a potential marker for aggressiveness and worse prognosis |
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https://doi.org/10.18632/oncotarget.22325
|
| 105574-105583 |
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| Lipopolysaccharidecoated CuS nanoparticles promoted anticancer and antimetastatic effect by immunophotothermal therapy |
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https://doi.org/10.18632/oncotarget.22331
|
| 105584-105595 |
|
| Apatinib is effective for treatment of advanced hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.22337
|
| 105596-105605 |
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| Pilot study: molecular risk factors for diagnosing sporadic Parkinson's disease based on gene expression in blood in MPTPinduced rhesus monkeys |
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https://doi.org/10.18632/oncotarget.22348
|
| 105606-105614 |
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| Indirubin a bisindole alkaloid from Isatis indigotica reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling |
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https://doi.org/10.18632/oncotarget.22350
|
| 105615-105629 |
|
| Relationship between expression of cyclooxygenase 2 and neovascularization in human pterygia |
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https://doi.org/10.18632/oncotarget.22351
|
| 105630-105636 |
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| Survivin overexpression is potentially associated with pituitary adenoma invasiveness |
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https://doi.org/10.18632/oncotarget.22354
|
| 105637-105647 |
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| Altered network efficiency of functional brain networks in patients with breast cancer after chemotherapy |
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https://doi.org/10.18632/oncotarget.22358
|
| 105648-105661 |
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| Activation of Nrf2 by MIND417 protects osteoblasts from hydrogen peroxideinduced oxidative stress |
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https://doi.org/10.18632/oncotarget.22360
|
| 105662-105672 |
|
| A green and facile preparation approach licochalcone A capped on hollow gold nanoparticles for improving the solubility and dissolution of anticancer natural product |
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https://doi.org/10.18632/oncotarget.22387
|
| 105673-105681 |
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| Diffusionweighted MRIderived ADC values reflect collagen I content in PDX models of uterine cervical cancer |
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https://doi.org/10.18632/oncotarget.22388
|
| 105682-105691 |
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| Activation of the NGF/TrkA signaling pathway attenuates diabetic erectile dysfunction |
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https://doi.org/10.18632/oncotarget.22389
|
| 105692-105702 |
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| Ginseng Rh2 protects endometrial cells from oxygen glucose deprivation/reoxygenation |
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https://doi.org/10.18632/oncotarget.22390
|
| 105703-105713 |
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| MutTrelated proteins are novel progression and prognostic markers for colorectal cancer |
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https://doi.org/10.18632/oncotarget.22393
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| 105714-105726 |
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| MerTK inhibition by RXDX106 in MerTK activated gastric cancer cell lines |
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https://doi.org/10.18632/oncotarget.22394
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| 105727-105734 |
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| Synthetic nickelcontaining superoxide dismutase attenuates paraphenylenediamineinduced bladder dysfunction in rats |
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https://doi.org/10.18632/oncotarget.22395
|
| 105735-105748 |
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| Exploring the effect of primary tumor sidedness on therapeutic efficacy across treatment lines in patients with metastatic colorectal cancer: analysis of FIRE3 AIOKRK0306 |
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https://doi.org/10.18632/oncotarget.22396
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| 105749-105760 |
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| Preliminary quantitative proteomics analysis in chronic and latent Keshan disease by iTRAQ labeling approach |
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https://doi.org/10.18632/oncotarget.22397
|
| 105761-105774 |
|
| Serum SDF1 levels are a reliable diagnostic marker of feline mammary carcinoma discriminating HER2overexpressing tumors from other subtypes |
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https://doi.org/10.18632/oncotarget.22398
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| 105775-105789 |
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| Development of a novel biomarker model for predicting preoperative lymph node metastatic extent in esophageal squamous cell carcinoma1 |
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https://doi.org/10.18632/oncotarget.22399
|
| 105790-105799 |
|
| Two new species of betatorqueviruses identified in a human melanoma that metastasized to the brain |
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https://doi.org/10.18632/oncotarget.22400
|
| 105800-105808 |
|
| Usefulness of plasma matrix metalloproteinase9 levels in prediction of inhospital mortality in patients who received emergent percutaneous coronary artery intervention following myocardial infarction |
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https://doi.org/10.18632/oncotarget.22401
|
| 105809-105818 |
|
| NMRbased metabolomic techniques identify potential urinary biomarkers for early colorectal cancer detection |
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https://doi.org/10.18632/oncotarget.22402
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| 105819-105831 |
|
| RNAsequencing reveals genomewide long noncoding RNAs profiling associated with early development of diabetic nephropathy |
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https://doi.org/10.18632/oncotarget.22405
|
| 105832-105847 |
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| Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde |
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https://doi.org/10.18632/oncotarget.22406
|
| 105848-105859 |
|
| Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2mediated matrix metalloproteinase2 expression |
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https://doi.org/10.18632/oncotarget.22407
|
| 105860-105872 |
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| MiR20a5p promotes radioresistance by targeting NPAS2 in nasopharyngeal cancer cells |
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https://doi.org/10.18632/oncotarget.22411
|
| 105873-105881 |
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| Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione |
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https://doi.org/10.18632/oncotarget.22413
|
| 105882-105904 |
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| GSTT1 GSTP1 and GSTM1 genetic variants are associated with survival in previously untreated metastatic breast cancer |
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https://doi.org/10.18632/oncotarget.22450
|
| 105905-105914 |
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| Telomere length associated with the risks of highrisk and ischemic stroke in southern Chinese Han population |
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https://doi.org/10.18632/oncotarget.22509
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| 105915-105922 |
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| Insulin receptor substrate4 interacts with ubiquitinspecific protease 18 to activate the Jak/STAT signaling pathway |
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https://doi.org/10.18632/oncotarget.22510
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| 105923-105935 |
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| Elevated CEA is associated with worse survival in recurrent rectal cancer |
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https://doi.org/10.18632/oncotarget.22511
|
| 105936-105941 |
|
| A premature stop codon within the tvb receptor gene results in decreased susceptibility to infection by avian leukosis virus subgroups B D and E |
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https://doi.org/10.18632/oncotarget.22512
|
| 105942-105956 |
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| HLAG+3027 polymorphism is associated with tumor relapse in pediatric Hodgkin’s lymphoma |
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https://doi.org/10.18632/oncotarget.22515
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| 105957-105970 |
|
| Polymorphisms in matrix metalloproteinases 2 3 and 8 increase recurrence and mortality risk by regulating enzyme activity in gastric adenocarcinoma |
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https://doi.org/10.18632/oncotarget.22516
|
| 105971-105983 |
|
| Decisive role of P42/44 mitogenactivated protein kinase in Δ9tetrahydrocannabinolinduced migration of human mesenchymal stem cells |
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https://doi.org/10.18632/oncotarget.22517
|
| 105984-105994 |
|
| 18cineole prevents UVBinduced skin carcinogenesis by targeting the aryl hydrocarbon receptor |
|
https://doi.org/10.18632/oncotarget.22519
|
| 105995-106008 |
|
| Role of preoperative magnetic resonance imaging and histological assessment in identifying patients with a low risk of endometrial cancer: a Korean Gynecologic Oncology Group ancillary study |
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https://doi.org/10.18632/oncotarget.22520
|
| 106009-106016 |
|
| Gene delivery and gene expression in vertebrate using baculovirus Bombyx mori nucleopolyhedrovirus vector |
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https://doi.org/10.18632/oncotarget.22522
|
| 106017-106025 |
|
| RTL1 promotes melanoma proliferation by regulating Wnt/βcatenin signalling |
|
https://doi.org/10.18632/oncotarget.22523
|
| 106026-106037 |
|
| FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice |
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https://doi.org/10.18632/oncotarget.22524
|
| 106038-106049 |
|
| TLR2/MyD88 pathwaydependent regulation of dendritic cells by dengue virus promotes antibodydependent enhancement via Th2biased immunity |
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https://doi.org/10.18632/oncotarget.22525
|
| 106050-106070 |
|
| CXCL8 derived from tumorassociated macrophages and esophageal squamous cell carcinomas contributes to tumor progression by promoting migration and invasion of cancer cells |
|
https://doi.org/10.18632/oncotarget.22526
|
| 106071-106088 |
|
| Elevated pretreatment platelet distribution width and platelet count predict poor prognosis in nasopharyngeal carcinoma |
|
https://doi.org/10.18632/oncotarget.22528
|
| 106089-106097 |
|
| Altered expression of differential gene and lncRNA in the lower thoracic spinal cord on different time courses of experimental obstructive jaundice model accompanied with altered peripheral nociception in rats |
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https://doi.org/10.18632/oncotarget.22532
|
| 106098-106112 |
Clinical Research Papers
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| Comparison of hydrocortisone and prednisone in the glucocorticoid replacement therapy postadrenalectomy of Cushing’s Syndrome |
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https://doi.org/10.18632/oncotarget.20597
|
| 106113-106120 |
|
| Impact of socioeconomic status on survival of colorectal cancer patients |
|
https://doi.org/10.18632/oncotarget.20859
|
| 106121-106131 |
Reviews
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| Immune system and melanoma biology: a balance between immunosurveillance and immune escape |
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https://doi.org/10.18632/oncotarget.22190
|
| 106132-106142 |
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