VOLUME 6 (2015)
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See Miyakawa et al. HepG2 cells were transfected with plasmids encoding SHBs-FLAG and HA-tetherin. After 24 h, the cells were fixed, permeabilized, and stained with anti-FLAG (green) and anti-HA (red), followed by confocal microscopic analysis. Scale bar, 10 μm.
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Table of Contents
Editorial: Immunology
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| The herpesvirus stealth program |
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https://doi.org/10.18632/oncotarget.5261
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| 21761-21762 |
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| Fatty acid synthesis and NLRP3inflammasome |
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https://doi.org/10.18632/oncotarget.4781
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| 21765-21766 |
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| A Hrd way for MHCII expression |
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https://doi.org/10.18632/oncotarget.4799
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| 21767-21768 |
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| IDOGCN2 and autophagy in inflammation |
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https://doi.org/10.18632/oncotarget.4846
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| 21771-21772 |
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| TCR signals fuel Treg cells |
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https://doi.org/10.18632/oncotarget.4881
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| 21773-21774 |
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| IL37 restrains autoimmune diseases |
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https://doi.org/10.18632/oncotarget.4887
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| 21775-21776 |
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| Thymic involution beyond Tcell insufficiency |
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https://doi.org/10.18632/oncotarget.4970
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| 21777-21778 |
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| OX40/OX40L axis: not a friend in autoimmunity |
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https://doi.org/10.18632/oncotarget.4973
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| 21779-21780 |
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| Protein conformation in a vaccine matters |
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https://doi.org/10.18632/oncotarget.5102
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| 21781-21782 |
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| PD1: Dual guard for immunopathology |
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https://doi.org/10.18632/oncotarget.4787
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| 21783-21784 |
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| Regulation of T follicular helper cells by ICOS |
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https://doi.org/10.18632/oncotarget.4798
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| 21785-21786 |
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| Notch controls effector CD8+ T cell differentiation |
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https://doi.org/10.18632/oncotarget.4886
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| 21787-21788 |
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| TPL2 mediates IL17R signaling in neuroinflammation |
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https://doi.org/10.18632/oncotarget.4888
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| 21789-21790 |
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| Uncovering HIV1infected cells |
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https://doi.org/10.18632/oncotarget.4974
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| 21791-21792 |
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| RUNX1 as a recombinase cofactor |
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https://doi.org/10.18632/oncotarget.5488
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| 21793-21794 |
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| Natural Th1 cells: escape from neglect |
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https://doi.org/10.18632/oncotarget.5489
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| 21795-21796 |
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| NK cell exhaustion: bad news for chronic disease |
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https://doi.org/10.18632/oncotarget.5490
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| 21797-21798 |
Research Perspectives
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| Cdk5 and Foxc2 – a new relationship in the lymphatic vasculature |
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https://doi.org/10.18632/oncotarget.4848
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| 21799-21801 |
Priority Research Papers
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| MicroRNA224 is implicated in lung cancer pathogenesis through targeting caspase3 and caspase7 |
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https://doi.org/10.18632/oncotarget.5224
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| 21802-21815 |
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| Perifosine as a potential novel antitelomerase therapy |
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https://doi.org/10.18632/oncotarget.5200
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| 21816-21826 |
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| In vivo hematopoietic Myc activation directs a transcriptional signature in endothelial cells within the bone marrow microenvironment |
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https://doi.org/10.18632/oncotarget.5217
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| 21827-21839 |
Research Papers: Immunology
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| Molecular dissection of HBV evasion from restriction factor tetherin: A new perspective for antiviral cell therapy |
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https://doi.org/10.18632/oncotarget.4808
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| 21840-21852 |
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| Human CD4+ T cells require exogenous cystine for glutathione and DNA synthesis |
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https://doi.org/10.18632/oncotarget.5213
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| 21853-21864 |
Research Papers
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| The potential utility of acetyltanshinone IIA in the treatment of HER2overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways |
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https://doi.org/10.18632/oncotarget.4156
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| 21865-21877 |
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| The pioneer factor PBX1 is a novel driver of metastatic progression in ERαpositive breast cancer |
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https://doi.org/10.18632/oncotarget.4243
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| 21878-21891 |
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| Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a subpopulation of stemlike mitochondrialrich cancer cells |
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https://doi.org/10.18632/oncotarget.5260
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| 21892-21905 |
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| Regulation of sensitivity of tumor cells to antitubulin drugs by Cdk1TAZ signalling |
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https://doi.org/10.18632/oncotarget.4259
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| 21906-21917 |
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| Curcumin inhibits in vitro and in vivo chronic myelogenous leukemia cells growth: a possible role for exosomal disposal of miR21 |
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https://doi.org/10.18632/oncotarget.4204
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| 21918-21933 |
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| Knockdown of long noncoding RNA HOTAIR inhibits malignant biological behaviors of human glioma cells via modulation of miR326 |
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https://doi.org/10.18632/oncotarget.4290
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| 21934-21949 |
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| Predominant RabGTPase amplicons contributing to oral squamous cell carcinoma progression to metastasis |
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https://doi.org/10.18632/oncotarget.4277
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| 21950-21963 |
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| DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers |
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https://doi.org/10.18632/oncotarget.4157
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| 21964-21978 |
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| Overexpressed tryptophanyltRNA synthetase an angiostatic protein enhances oral cancer cell invasiveness |
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https://doi.org/10.18632/oncotarget.4273
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| 21979-21992 |
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| EGFR blockade prevents glioma escape from BRAFV600E targeted therapy |
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https://doi.org/10.18632/oncotarget.4014
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| 21993-22005 |
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| MicroRNA153/Nrf2/GPx1 pathway regulates radiosensitivity and stemness of glioma stem cells via reactive oxygen species |
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https://doi.org/10.18632/oncotarget.4292
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| 22006-22027 |
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| Mutational and gene fusion analyses of primary large cell and large cell neuroendocrine lung cancer |
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https://doi.org/10.18632/oncotarget.4314
|
| 22028-22037 |
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| ‘Cut from the same cloth’: Shared microsatellite variants among cancers link to ectodermal tissuesneural tube and crest cells |
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https://doi.org/10.18632/oncotarget.4194
|
| 22038-22047 |
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| A contrasting function for miR137 in embryonic mammogenesis and adult breast carcinogenesis |
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https://doi.org/10.18632/oncotarget.4218
|
| 22048-22059 |
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| Downregulation of cSRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass |
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https://doi.org/10.18632/oncotarget.4279
|
| 22060-22071 |
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| Combination of body mass index and oxidized low density lipoprotein receptor 1 in prognosis prediction of patients with squamous nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.4299
|
| 22072-22080 |
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| Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapydependent breast tumor regression |
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https://doi.org/10.18632/oncotarget.4203
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| 22081-22097 |
|
| Functional relevance of a six mesenchymal gene signature in epithelialmesenchymal transition EMT reversal by the triple angiokinase inhibitor nintedanib BIBF1120 |
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https://doi.org/10.18632/oncotarget.4300
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| 22098-22113 |
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| Analysis of the molecular features of rectal carcinoid tumors to identify new biomarkers that predict biological malignancy |
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https://doi.org/10.18632/oncotarget.4294
|
| 22114-22125 |
|
| Epigenetic silencing of NKD2 a major component of Wnt signaling promotes breast cancer growth |
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https://doi.org/10.18632/oncotarget.4244
|
| 22126-22138 |
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| Anticancer effect of snake venom toxin through down regulation of AP1 mediated PRDX6 expression |
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https://doi.org/10.18632/oncotarget.4192
|
| 22139-22151 |
|
| Discovery of benzo[e]pyridoindolones as kinase inhibitors that disrupt mitosis exit while erasing AMPKThr172 phosphorylation on the spindle |
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https://doi.org/10.18632/oncotarget.4158
|
| 22152-22166 |
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| Tivantinib ARQ 197 affects the apoptotic and proliferative machinery downstream of cMET: role of Mcl1 Bclxl and Cyclin B1 |
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https://doi.org/10.18632/oncotarget.4240
|
| 22167-22178 |
|
| Genomewide mutation profiles of colorectal tumors and associated liver metastases at the exome and transcriptome levels |
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https://doi.org/10.18632/oncotarget.4246
|
| 22179-22190 |
|
| Endotheliallike malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumorderived angiogenic response |
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https://doi.org/10.18632/oncotarget.4339
|
| 22191-22205 |
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| Upfront molecular testing in patients with advanced gastroesophageal cancer: Is it time yet |
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https://doi.org/10.18632/oncotarget.4247
|
| 22206-22213 |
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| PYK2 integrates growth factor and cytokine receptors signaling and potentiates breast cancer invasion via a positive feedback loop |
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https://doi.org/10.18632/oncotarget.4257
|
| 22214-22226 |
|
| Stathmin and phosphostathmin protein signature is associated with survival outcomes of breast cancer patients |
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https://doi.org/10.18632/oncotarget.4276
|
| 22227-22238 |
|
| Osteopontin OPN/SPP1 isoforms collectively enhance tumor cell invasion and dissemination in esophageal adenocarcinoma |
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https://doi.org/10.18632/oncotarget.4161
|
| 22239-22257 |
|
| Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells |
|
https://doi.org/10.18632/oncotarget.4165
|
| 22258-22269 |
|
| AS1411conjugated gold nanospheres and their potential for breast cancer therapy |
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https://doi.org/10.18632/oncotarget.4207
|
| 22270-22281 |
|
| Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of patched and increase chemotherapy efficiency on melanoma cells |
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https://doi.org/10.18632/oncotarget.4162
|
| 22282-22297 |
|
| Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAFdriven colorectal carcinoma |
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https://doi.org/10.18632/oncotarget.4263
|
| 22298-22309 |
|
| Regulation of split anergy in natural killer cells by inhibition of cathepsins C and H and cystatin F |
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https://doi.org/10.18632/oncotarget.4208
|
| 22310-22327 |
|
| Targeting Bcl2 stability to sensitize cells harboring oncogenic ras |
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https://doi.org/10.18632/oncotarget.4084
|
| 22328-22337 |
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| AntiGCSF treatment induces protective tumor immunity in mouse colon cancer by promoting protective NK cell macrophage and T cell responses |
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https://doi.org/10.18632/oncotarget.4169
|
| 22338-22347 |
|
| ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of drivernegative melanoma |
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https://doi.org/10.18632/oncotarget.4255
|
| 22348-22360 |
|
| CRISPR/Cas9mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells |
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https://doi.org/10.18632/oncotarget.4293
|
| 22361-22374 |
|
| Multifaceted role of TREX2 in the skin defense against UVinduced skin carcinogenesis |
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https://doi.org/10.18632/oncotarget.4296
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| 22375-22396 |
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| siRNA knockdown of mitochondrial thymidine kinase 2 TK2 sensitizes human tumor cells to gemcitabine |
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https://doi.org/10.18632/oncotarget.4272
|
| 22397-22409 |
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| MIF secreted by human hepatic sinusoidal endothelial cells promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis |
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https://doi.org/10.18632/oncotarget.4198
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| 22410-22423 |
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| Intact LKB1 activity is required for survival of dormant ovarian cancer spheroids |
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https://doi.org/10.18632/oncotarget.4211
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| 22424-22438 |
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| miR620 promotes tumor radioresistance by targeting 15hydroxyprostaglandin dehydrogenase HPGD |
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https://doi.org/10.18632/oncotarget.4210
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| 22439-22451 |
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| miRNA3373p suppresses neuroblastoma progression by repressing the transcription of matrix metalloproteinase 14 |
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https://doi.org/10.18632/oncotarget.4311
|
| 22452-22466 |
|
| DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyperactivation |
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https://doi.org/10.18632/oncotarget.4164
|
| 22467-22479 |
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| Modulation of cerebral endothelial cell function by TGFβ in glioblastoma: VEGFdependent angiogenesis versus endothelial mesenchymal transition |
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https://doi.org/10.18632/oncotarget.4310
|
| 22480-22495 |
|
| Trop2 is a novel target for solid cancer therapy with sacituzumab govitecan IMMU132 an antibodydrug conjugate ADC* |
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https://doi.org/10.18632/oncotarget.4318
|
| 22496-22512 |
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| The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer |
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https://doi.org/10.18632/oncotarget.4154
|
| 22513-22525 |
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| The transcriptome and miRNome profiling of glioblastoma tissues and peritumoral regions highlights molecular pathways shared by tumors and surrounding areas and reveals differences between shortterm and longterm survivors |
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https://doi.org/10.18632/oncotarget.4151
|
| 22526-22552 |
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| Alternative splicing of synuclein gamma in endometrial cancer: identification of a novel isoform |
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https://doi.org/10.18632/oncotarget.4155
|
| 22553-22563 |
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| Regulation of migration and invasion by Tolllike receptor9 signaling network in prostate cancer |
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https://doi.org/10.18632/oncotarget.4197
|
| 22564-22574 |
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| Enhanced nucleotide excision repair capacity in lung cancer cells by preconditioning with DNAdamaging agents |
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https://doi.org/10.18632/oncotarget.4610
|
| 22575-22586 |
|
| EphA6 promotes angiogenesis and prostate cancer metastasis and is associated with human prostate cancer progression |
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https://doi.org/10.18632/oncotarget.4088
|
| 22587-22597 |
|
| Dynaminrelated protein Drp1 is required for Bax translocation to mitochondria in response to irradiationinduced apoptosis |
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https://doi.org/10.18632/oncotarget.4200
|
| 22598-22612 |
|
| Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oralspecific chemical carcinogenesis model |
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https://doi.org/10.18632/oncotarget.4209
|
| 22613-22623 |
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| Metformin inhibits cell cycle progression of Bcell chronic lymphocytic leukemia cells |
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https://doi.org/10.18632/oncotarget.4168
|
| 22624-22640 |
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| Role of PAR4 in ovarian cancer |
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https://doi.org/10.18632/oncotarget.4010
|
| 22641-22652 |
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| The gainoffunction GLI1 transcription factor TGLI1 enhances expression of VEGFC and TEM7 to promote glioblastoma angiogenesis |
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https://doi.org/10.18632/oncotarget.4248
|
| 22653-22665 |
|
| The MDM2inhibitor Nutlin3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.4433
|
| 22666-22679 |
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| RTVP1 promotes mesenchymal transformation of glioma via a STAT3/IL6dependent positive feedback loop |
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https://doi.org/10.18632/oncotarget.4205
|
| 22680-22697 |
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| MYC amplifications in myeloma cell lines: correlation with MYCinhibitor efficacy |
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https://doi.org/10.18632/oncotarget.4245
|
| 22698-22705 |
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| Epigenetic inactivation of the candidate tumor suppressor gene ASC/TMS1 in human renal cell carcinoma and its role as a potential therapeutic target |
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https://doi.org/10.18632/oncotarget.4256
|
| 22706-22723 |
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| Low DICER1 expression is associated with poor clinical outcome in adrenocortical carcinoma |
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https://doi.org/10.18632/oncotarget.4261
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| 22724-22733 |
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| The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia |
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https://doi.org/10.18632/oncotarget.4212
|
| 22734-22749 |
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| A retrospective analysis of cisplatin pemetrexed and bevacizumab in previously treated nonsmallcell lung cancer |
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https://doi.org/10.18632/oncotarget.4262
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| 22750-22757 |
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| βcatenin stabilization enhances SS18SSX2driven synovial sarcomagenesis and blocks the mesenchymal to epithelial transition |
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https://doi.org/10.18632/oncotarget.4283
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| 22758-22766 |
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| Fbox protein FBXO22 mediates polyubiquitination and degradation of KLF4 to promote hepatocellular carcinoma progression |
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https://doi.org/10.18632/oncotarget.4082
|
| 22767-22775 |
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| Nanovehicles as a novel target strategy for hyperthermic intraperitoneal chemotherapy: a multidisciplinary study of peritoneal carcinomatosis |
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https://doi.org/10.18632/oncotarget.4309
|
| 22776-22798 |
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| Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3 |
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https://doi.org/10.18632/oncotarget.4332
|
| 22799-22811 |
|
| Nextgeneration sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.4333
|
| 22812-22821 |
|
| Antitumor effect of inhibition of IL6 signaling in mucoepidermoid carcinoma |
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https://doi.org/10.18632/oncotarget.4477
|
| 22822-22835 |
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| Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation |
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https://doi.org/10.18632/oncotarget.4479
|
| 22836-22856 |
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| Macrophage depletion reduces postsurgical tumor recurrence and metastatic growth in a spontaneous murine model of melanoma |
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https://doi.org/10.18632/oncotarget.3127
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| 22857-22868 |
|
| p53 controls colorectal cancer cell invasion by inhibiting the NFκBmediated activation of Fascin |
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https://doi.org/10.18632/oncotarget.5137
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| 22869-22879 |
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| Coexpression of CXCL8 and HIF1α is associated with metastasis and poor prognosis in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.4412
|
| 22880-22889 |
|
| Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis |
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https://doi.org/10.18632/oncotarget.4413
|
| 22890-22904 |
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| In vivo selection for spinederived highly metastatic lung cancer cells is associated with increased migration inflammation and decreased adhesion |
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https://doi.org/10.18632/oncotarget.4416
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| 22905-22917 |
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| The E3 ubiquitin ligase Cblb improves the prognosis of RANK positive breast cancer patients by inhibiting RANKLinduced cell migration and metastasis |
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https://doi.org/10.18632/oncotarget.4382
|
| 22918-22933 |
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| Small molecule/ML327 mediated transcriptional derepression of Ecadherin and inhibition of epithelialtomesenchymal transition |
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https://doi.org/10.18632/oncotarget.4473
|
| 22934-22948 |
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| Molecular analysis of ovarian mucinous carcinoma reveals different cell of origins |
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https://doi.org/10.18632/oncotarget.5146
|
| 22949-22958 |
Clinical Research Papers
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| Tissue specific expression of extracellular microRNA in human breast cancers and normal human breast tissue in vivo |
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https://doi.org/10.18632/oncotarget.4038
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| 22959-22969 |
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| Association of the intermediate filament nestin with cancer stage: a metaanalysis based on 223 positive/high nestin cases and 460 negative/low casefree controls |
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https://doi.org/10.18632/oncotarget.4042
|
| 22970-22977 |
|
| Influence of age on predictiveness of genetic risk score for prostate cancer in a Chinese hospitalbased biopsy cohort |
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https://doi.org/10.18632/oncotarget.3938
|
| 22978-22984 |
|
| Effect of tumor size on breast cancerspecific survival stratified by joint hormone receptor status in a SEER populationbased study |
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https://doi.org/10.18632/oncotarget.3945
|
| 22985-22995 |
|
| MicroRNA143 is a putative predictive factor for the response to fluoropyrimidinebased chemotherapy in patients with metastatic colorectal cancer |
|
https://doi.org/10.18632/oncotarget.4035
|
| 22996-23007 |
|
| Maintenance chemotherapy in children with ALL exerts metronomiclike thrombospondin1 associated antiendothelial effect |
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https://doi.org/10.18632/oncotarget.3984
|
| 23008-23014 |
|
| Prognostic value of HPVmRNA in sentinel lymph nodes of cervical cancer patients with pN0status |
|
https://doi.org/10.18632/oncotarget.4132
|
| 23015-23025 |
|
| Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor ÂÂprognosis |
|
https://doi.org/10.18632/oncotarget.4854
|
| 23026-23035 |
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