VOLUME 6 (2015)
Table of Contents
Errata
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| Erratum: Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms |
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https://doi.org/10.18632/oncotarget.3810
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| 7364 |
Reviews
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| Targeting AMPK for cancer prevention and treatment |
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https://doi.org/10.18632/oncotarget.3629
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| 7365-7378 |
Priority Research Papers
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| Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma |
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https://doi.org/10.18632/oncotarget.3132
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| 7379-7389 |
|
| The SNP rs6500843 in 16p133 is associated with survival specifically among chemotherapytreated breast cancer patients |
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https://doi.org/10.18632/oncotarget.3506
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| 7390-7407 |
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| Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma |
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https://doi.org/10.18632/oncotarget.3510
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| 7408-7423 |
Research Papers: Gerotarget (Focus on Aging)
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| Modulation of TGFbeta 2 levels by lamin A in U2OS osteoblastlike cells: understanding the osteolytic process triggered by altered lamins |
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https://doi.org/10.18632/oncotarget.3232
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| 7424-7437 |
Research Papers
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| Dietinduced hypercholesterolemia promotes androgenindependent prostate cancer metastasis via IQGAP1 and caveolin1 |
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https://doi.org/10.18632/oncotarget.3476
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| 7438-7453 |
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| MiR34a suppresses amphiregulin and tumor metastatic potential of head and neck squamous cell carcinoma HNSCC |
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https://doi.org/10.18632/oncotarget.3148
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| 7454-7469 |
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| YB1 and MTA1 protein levels and not DNA or mRNA alterations predict for prostate cancer recurrence |
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https://doi.org/10.18632/oncotarget.3477
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| 7470-7480 |
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| MUTYH mediates the toxicity of combined DNA 6thioguanine and UVA radiation |
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https://doi.org/10.18632/oncotarget.3037
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| 7481-7492 |
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| Intratumoral diversity of telomere length in individual neuroblastoma tumors |
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https://doi.org/10.18632/oncotarget.2115
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| 7493-7503 |
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| TCGA data and patientderived orthotopic xenografts highlight pancreatic cancerassociated angiogenesis |
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https://doi.org/10.18632/oncotarget.3233
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| 7504-7521 |
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| Nutrient/serum starvation derived TRIPBr3 downregulation accelerates apoptosis by destabilizing XIAP |
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https://doi.org/10.18632/oncotarget.3112
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| 7522-7535 |
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| Adrenomedullin blockade induces regression of tumor neovessels through interference with vascular endothelialcadherin signalling |
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https://doi.org/10.18632/oncotarget.3167
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| 7536-7553 |
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| Antitumour effects of antibodies targeting the extracellular cysteinerich region of the receptor tyrosine kinase EphB4 |
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https://doi.org/10.18632/oncotarget.3199
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| 7554-7569 |
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| Elevated Src family kinase activity stabilizes Ecadherinbased junctions and collective movement of head and neck squamous cell carcinomas |
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https://doi.org/10.18632/oncotarget.3071
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| 7570-7583 |
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| NDRG4 a novel candidate tumor suppressor is a predictor of overall survival of colorectal cancer patients |
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https://doi.org/10.18632/oncotarget.3170
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| 7584-7596 |
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| Genomic differences between pure ductal carcinoma in situ and synchronous ductal carcinoma in situ with invasive breast cancer |
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https://doi.org/10.18632/oncotarget.3162
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| 7597-7607 |
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| BRCA1 regulates PIG3mediated apoptosis in a p53dependent manner |
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https://doi.org/10.18632/oncotarget.3263
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| 7608-7618 |
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| Kidneytype glutaminase GLS1 is a biomarker for pathologic diagnosis and prognosis of hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.3196
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| 7619-7631 |
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| Coculture of primary CLL cells with bone marrow mesenchymal cells CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo |
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https://doi.org/10.18632/oncotarget.2939
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| 7632-7643 |
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| HDAC9 promotes glioblastoma growth via TAZmediated EGFR pathway activation |
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https://doi.org/10.18632/oncotarget.3223
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| 7644-7656 |
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| A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation aggressiveness and resistance to temozolomide |
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https://doi.org/10.18632/oncotarget.3150
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| 7657-7674 |
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| miR145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells |
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https://doi.org/10.18632/oncotarget.3048
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| 7675-7685 |
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| A dual yet opposite growthregulating function of miR204 and its target XRN1 in prostate adenocarcinoma cells and neuroendocrinelike prostate cancer cells |
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https://doi.org/10.18632/oncotarget.3480
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| 7686-7700 |
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| Identifying the determinants of response to MDM2 inhibition |
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https://doi.org/10.18632/oncotarget.3116
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| 7701-7712 |
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| Adiposederived stem cells promote tumor initiation and accelerate tumor growth by interleukin6 production |
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https://doi.org/10.18632/oncotarget.3481
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| 7713-7726 |
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| TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause LiFraumeni syndrome |
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https://doi.org/10.18632/oncotarget.3115
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| 7727-7740 |
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| PTX3 gene activation in EGFinduced head and neck cancer cell metastasis |
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https://doi.org/10.18632/oncotarget.3482
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| 7741-7757 |
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| Skeletal muscle atrophy is attenuated in tumorbearing mice under chemotherapy by treatment with fish oil and selenium |
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https://doi.org/10.18632/oncotarget.3483
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| 7758-7773 |
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| Loss of miR200c upregulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.3484
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| 7774-7787 |
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| Gluconeogenesis lipogenesis and HBV replication are commonly regulated by PGC1αdependent pathway |
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https://doi.org/10.18632/oncotarget.3050
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| 7788-7803 |
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| AP1mediated chromatin looping regulates ZEB2 transcription: new insights into TNFαinduced epithelial–mesenchymal transition in triplenegative breast cancer |
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https://doi.org/10.18632/oncotarget.3158
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| 7804-7814 |
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| Inhibition of tumor growth by a newlyidentified activator for epidermal fatty acid binding protein |
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https://doi.org/10.18632/oncotarget.3485
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| 7815-7827 |
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| Knockdown of CD44 inhibits the invasion and metastasis of hepatocellular carcinoma both in vitro and in vivo by reversing epithelialmesenchymal transition |
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https://doi.org/10.18632/oncotarget.3488
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| 7828-7837 |
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| Gold nanoparticles AuNPs carrying antiEBVmiRBART73p inhibit growth of EBVpositive nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.3046
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| 7838-7850 |
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| Pleiotropic modes of action in tumor cells of RNASET2 an evolutionary highly conserved extracellular RNase |
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https://doi.org/10.18632/oncotarget.3490
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| 7851-7865 |
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| Downregulation of miR432 activates Wnt/βcatenin signaling and promotes human hepatocellular carcinoma proliferation |
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https://doi.org/10.18632/oncotarget.3492
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| 7866-7879 |
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| Vasohibin1 suppresses colon cancer |
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https://doi.org/10.18632/oncotarget.3493
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| 7880-7898 |
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| Upregulated lncRNAUCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR216b and activation of FGFR1/ERK signaling pathway |
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https://doi.org/10.18632/oncotarget.3219
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| 7899-7917 |
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| MicroRNA200a suppresses metastatic potential of side population cells in human hepatocellular carcinoma by decreasing ZEB2 |
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https://doi.org/10.18632/oncotarget.3486
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| 7918-7929 |
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| MiR101 reverses the hypomethylation of the LMO3 promoter in glioma cells |
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https://doi.org/10.18632/oncotarget.3181
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| 7930-7943 |
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| Deficiency of AMPK in CD8+ T cells suppresses their antitumor function by inducing protein phosphatasemediated cell death |
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https://doi.org/10.18632/oncotarget.3501
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| 7944-7958 |
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| Extracellular vesicles derived from renal cancer stem cells induce a protumorigenic phenotype in mesenchymal stromal cells |
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https://doi.org/10.18632/oncotarget.3503
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| 7959-7969 |
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| Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells |
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https://doi.org/10.18632/oncotarget.3419
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| 7970-7991 |
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| Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells |
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https://doi.org/10.18632/oncotarget.3505
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| 7992-8006 |
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| UV irradiation/cold shockmediated apoptosis is switched to bubbling cell death at low temperatures |
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https://doi.org/10.18632/oncotarget.3153
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| 8007-8018 |
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| Computational prediction and experimental validation of a novel synthesized panPIM inhibitor PI003 and its apoptosisinducing mechanisms in cervical cancer |
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https://doi.org/10.18632/oncotarget.3139
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| 8019-8035 |
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| The oncogenic role of JC virus T antigen in lens tumors without cell specificity of alternative splicing of its intron |
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https://doi.org/10.18632/oncotarget.3507
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| 8036-8045 |
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| Ku80 cooperates with CBP to promote COX2 expression and tumor growth |
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https://doi.org/10.18632/oncotarget.3508
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| 8046-8061 |
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| Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase |
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https://doi.org/10.18632/oncotarget.3509
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| 8062-8070 |
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| Systems biology networkbased discovery of a small molecule activator BLAD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer |
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https://doi.org/10.18632/oncotarget.3513
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| 8071-8088 |
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| MicroRNA31 functions as a tumor suppressor by regulating cell cycle and epithelialmesenchymal transition regulatory proteins in liver cancer |
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https://doi.org/10.18632/oncotarget.3512
|
| 8089-8102 |
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| Secreted uPAR isoform 2 uPAR7b is a novel direct target of miR221 |
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https://doi.org/10.18632/oncotarget.3516
|
| 8103-8114 |
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| Oncogenic mutations of thyroid hormone receptor β |
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https://doi.org/10.18632/oncotarget.3466
|
| 8115-8131 |
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| Silencing of voltagegated potassium channel KV93 inhibits proliferation in human colon and lung carcinoma cells |
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https://doi.org/10.18632/oncotarget.3517
|
| 8132-8143 |
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| Mitogenactivated protein kinase binding protein 1 MAPKBP1 is an unfavorable prognostic biomarker in cytogenetically normal acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.3519
|
| 8144-8154 |
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| Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process |
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https://doi.org/10.18632/oncotarget.2692
|
| 8155-8166 |
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| Activation of NRF2 by p62 and proteasome reduction in sphereforming breast carcinoma cells |
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https://doi.org/10.18632/oncotarget.3047
|
| 8167-8184 |
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| FOXM1: A novel drug target in gastroenteropancreatic neuroendocrine tumors |
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https://doi.org/10.18632/oncotarget.3600
|
| 8185-8199 |
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| Marine compounds inhibit growth of multiple myeloma in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.3362
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| 8200-8209 |
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| Ndrg2 promoter hypermethylation triggered by helicobacter pylori infection correlates with poor patients survival in human gastric carcinoma |
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https://doi.org/10.18632/oncotarget.3601
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| 8210-8225 |
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| MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition |
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https://doi.org/10.18632/oncotarget.3364
|
| 8226-8243 |
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| NFκBmediated miR124 suppresses metastasis of nonsmallcell lung cancer by targeting MYO10 |
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https://doi.org/10.18632/oncotarget.3135
|
| 8244-8254 |
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| Prognostic factors of survival in patients treated with nabpaclitaxel plus gemcitabine regimen for advanced or metastatic pancreatic cancer: A single institutional experience |
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https://doi.org/10.18632/oncotarget.3143
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| 8255-8260 |
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| Peripheral myeloidderived suppressor and T regulatory PD1 positive cells predict response to neoadjuvant shortcourse radiotherapy in rectal cancer patients |
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https://doi.org/10.18632/oncotarget.3014
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| 8261-8270 |
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| A novel HIF1αintegrinlinked kinase regulatory loop that facilitates hypoxiainduced HIF1α expression and epithelialmesenchymal transition in cancer cells |
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https://doi.org/10.18632/oncotarget.3186
|
| 8271-8285 |
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| miR93 promotes cell proliferation in gliomas through activation of PI3K/Akt signaling pathway |
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https://doi.org/10.18632/oncotarget.3221
|
| 8286-8299 |
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| Low molecular weight protein tyrosine phosphatase LMWPTP upregulation mediates malignant potential in colorectal cancer |
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https://doi.org/10.18632/oncotarget.3224
|
| 8300-8312 |
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| CD133 initiates tumors induces epithelialmesenchymal transition and increases metastasis in pancreatic cancer |
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https://doi.org/10.18632/oncotarget.3228
|
| 8313-8322 |
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| Zipperinteracting protein kinase promotes epithelialmesenchymal transition invasion and metastasis through AKT and NFkB signaling and is associated with metastasis and poor prognosis in gastric cancer patients |
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https://doi.org/10.18632/oncotarget.3200
|
| 8323-8338 |
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| Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine |
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https://doi.org/10.18632/oncotarget.3234
|
| 8339-8352 |
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| HOTAIR is a therapeutic target in glioblastoma |
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https://doi.org/10.18632/oncotarget.3229
|
| 8353-8365 |
Clinical Research Papers
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| Bloodbrain barrier permeability of gefitinib in patients with brain metastases from nonsmallcell lung cancer before and during whole brain radiation therapy |
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https://doi.org/10.18632/oncotarget.3187
|
| 8366-8376 |
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| Overexpression of thymidylate synthase TYMS is associated with aggressive tumor features and early PSA recurrence in prostate cancer |
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https://doi.org/10.18632/oncotarget.3107
|
| 8377-8387 |
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| Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasiarelated changes |
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https://doi.org/10.18632/oncotarget.3460
|
| 8388-8396 |
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| Synchronous occurrence of gastrointestinal stromal tumors and other digestive tract malignancies in the elderly |
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https://doi.org/10.18632/oncotarget.3108
|
| 8397-8406 |
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| MLH1 V384D polymorphism associates with poor response to EGFR tyrosine kinase inhibitors in patients with EGFR L858Rpositive lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.3511
|
| 8407-8417 |
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| 11CMethioninePET: A novel and sensitive tool for monitoring of early response to treatment in multiple myeloma |
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https://doi.org/10.18632/oncotarget.3053
|
| 8418-8429 |
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