The Oncosearch | Oncotarget

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas Research Paper

Thomas M. Cardillo, Maria B. Zalath, Roberto Arrojo, Robert M. Sharkey, Serengulam V. Govindan, Chien-Hsing Chang, David M. Goldenberg

Published Jan 30, 2024 · Vol. 15, No. 1 · pp. 144-158

Keywords: sacituzumab govitecan, Trop-2, SN-38, carboplatin, cisplatin

Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer Research Paper

Thomas M. Cardillo, Diane L. Rossi, Maria B. Zalath, Donglin Liu, Roberto Arrojo, Robert M. Sharkey, Chien-Hsing Chang, David M. Goldenberg

Published Oct 1, 2020 · Vol. 11, No. 43 · pp. 3849-3862

Keywords: sacituzumab govitecan, Trop-2, biomarker, RAD51, triple-negative breast cancer

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Correction

David M. Goldenberg, Thomas M. Cardillo, Serengulam V. Govindan, Edmund A. Rossi, Robert M. Sharkey

Published Feb 25, 2020 · Vol. 11, No. 10 · pp. 942-942

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Salvatore Lopez, Emanuele Perrone, Stefania Bellone, Elena Bonazzoli, Burak Zeybek, Chanhee Han, Joan Tymon-Rosario, Gary Altwerger, Gulden Menderes, Anna Bianchi, Luca Zammataro, Aranzazu Manzano, Paola Manara, Elena Ratner, Dan-Arin Silasi, Gloria S. Huang, Masoud Azodi, Peter E. Schwartz, Francesco Raspagliesi, Roberto Angioli, Natalia Buza, Pei Hui, Heather M. Bond, Alessandro D. Santin

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 560-570

Keywords: sacituzumab govitecan, IMMU-132, uterine carcinosarcoma, trop-2

Correction: TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT Correction

Xinxing Li, Shifeng Teng, Yanyan Zhang, Weigang Zhang, Xianwen Zhang, Kai Xu, Houshan Yao, Jun Yao, Haolu Wang, Xiaowen Liang, Zhiqian Hu

Published Oct 23, 2019 · Vol. 10, No. 60 · pp. 6540-6540

The emergence of trophoblast cell-surface antigen 2 (TROP-2) as a novel cancer target Review

David M. Goldenberg, Rhona Stein, Robert M. Sharkey

Published Jun 22, 2018 · Vol. 9, No. 48 · pp. 28989-29006

The trophoblast cell surface antigen 2 and miR-125b axis in urothelial bladder cancer Research Paper

Chiara Avellini, Caterina Licini, Raffaella Lazzarini, Rosaria Gesuita, Emanuela Guerra, Giovanni Tossetta, Clara Castellucci, Stefano Raffaele Giannubilo, Antonio Procopio, Saverio Alberti, Roberta Mazzucchelli, Fabiola Olivieri, Daniela Marzioni

Published Apr 25, 2017 · Vol. 8, No. 35 · pp. 58642-58653

TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT Research Paper

Xinxing Li, Shifeng Teng, Yanyan Zhang, Weigang Zhang, Xianwen Zhang, Kai Xu, Houshan Yao, Jun Yao, Haolu Wang, Xiaowen Liang, Zhiqian Hu

Published Apr 3, 2017 · Vol. 8, No. 29 · pp. 47052-47063

Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression Research Paper

Antonio Agostini, Marta Brunetti, Ben Davidson, Claes G. TropÃ©, Sverre Heim, Ioannis Panagopoulos, Francesca Micci

Published Mar 1, 2017 · Vol. 8, No. 13 · pp. 21554-21560

Association of tumor TROP2 expression with prognosis varies among lung cancer subtypes Research Paper

Kentaro Inamura, Yusuke Yokouchi, Maki Kobayashi, Hironori Ninomiya, Rie Sakakibara, Sophia Subat, Hiroko Nagano, Kimie Nomura, Sakae Okumura, Tomoko Shibutani, Yuichi Ishikawa

Published Feb 23, 2017 · Vol. 8, No. 17 · pp. 28725-28735

Recurrent fusion transcripts in squamous cell carcinomas of the vulva Research Paper

Marta Brunetti, Antonio Agostini, Ben Davidson, Claes G TropÃ©, Sverre Heim, Ioannis Panagopoulos, Francesca Micci

Published Feb 7, 2017 · Vol. 8, No. 10 · pp. 16843-16850

Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer Research Paper

Olga A. Timofeeva, Nancy Palechor-Ceron, Guanglei Li, Hang Yuan, Ewa Krawczyk, Xiaogang Zhong, Geng Liu, Geeta Upadhyay, Aleksandra Dakic, Songtao Yu, Shuang Fang, Sujata Choudhury, Xueping Zhang, Andrew Ju, Myeong-Seon Lee, Han C. Dan, Youngmi Ji, Yong Hou, Yun-Ling Zheng, Chris Albanese, Johng Rhim, Richard Schlegel, Anatoly Dritschilo, Xuefeng Liu

Published Dec 21, 2016 · Vol. 8, No. 14 · pp. 22741-22758

High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells Research Paper

Jinhan Xie, Christina MÃ¸lck, Sophie Paquet-Fifield, Lisa Butler, Australian Prostate Cancer Bioresource, Erica Sloan, Sabatino Ventura, FrÃ©dÃ©ric Hollande

Published Jun 7, 2016 · Vol. 7, No. 28 · pp. 44492-44504

The tumor-inhibitory effectiveness of a novel anti-Trop2 Fab conjugate in pancreatic cancer Research Paper

Yuan Mao, Xiaoying Wang, Feng Zheng, Changjun Wang, Qi Tang, Xiaojun Tang, Ning Xu, Huiling Zhang, Dawei Zhang, Lin Xiong, Jie Liang, Jin Zhu

Published Apr 1, 2016 · Vol. 7, No. 17 · pp. 24810-24823

Trop2 is overexpressed in gastric cancer and predicts poor prognosis Research Paper

Wei Zhao, Huijun Zhu, Shu Zhang, Hongmei Yong, Wei Wang, Yan Zhou, Bing Wang, Jinbo Wen, Zhenning Qiu, Guipeng Ding, Zhenqing Feng, Jin Zhu

Published Dec 22, 2015 · Vol. 7, No. 5 · pp. 6136-6145

Erratum: Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts Errata

Marco Trerotola, Kirat K. Ganguly, Ladan Fazli, Carmine Fedele, Huimin Lu, Anindita Dutta, Qin Liu, Tiziana De Angelis, Luke W. Riddell, Natalia A. Riobo, Martin E. Gleave, Amina Zoubeidi, Richard G. Pestell, Dario C. Altieri, Lucia R. Languino

Published Oct 20, 2015 · Vol. 6, No. 32 · pp. 34038

Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Research Paper

David M. Goldenberg, Thomas M. Cardillo, Serengulam V. Govindan, Edmund A. Rossi, Robert M. Sharkey

Published Jun 18, 2015 · Vol. 6, No. 26 · pp. 22496-22512

Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts Research Paper

Marco Trerotola, Kirat K. Ganguly, Ladan Fazli, Carmine Fedele, Huimin Lu, Anindita Dutta, Qin Liu, Tiziana De Angelis, Luke W. Riddell, Natalia A. Riobo, Martin E. Gleave, Amina Zoubeidi, Richard G. Pestell, Dario C. Altieri, Lucia R. Languino

Published Apr 29, 2015 · Vol. 6, No. 16 · pp. 14318-14328

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC Research Paper

Kaihua Zhang, Lamont Jones, Sora Lim, Christopher A. Maher, Douglas Adkins, James Lewis, Randall J. Kimple, Elana J. Fertig, Christine H. Chung, Andreas Herrlich, Matthew J. Ellis, Brian A. Van Tine, Loren S. Michel

Published Sep 2, 2014 · Vol. 5, No. 19 · pp. 9281-9294

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Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas Research Paper

Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer Research Paper

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Correction

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Correction: TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT Correction

The emergence of trophoblast cell-surface antigen 2 (TROP-2) as a novel cancer target Review

The trophoblast cell surface antigen 2 and miR-125b axis in urothelial bladder cancer Research Paper

TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT Research Paper

Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression Research Paper

Association of tumor TROP2 expression with prognosis varies among lung cancer subtypes Research Paper

Recurrent fusion transcripts in squamous cell carcinomas of the vulva Research Paper

Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer Research Paper

High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells Research Paper

The tumor-inhibitory effectiveness of a novel anti-Trop2 Fab conjugate in pancreatic cancer Research Paper

Trop2 is overexpressed in gastric cancer and predicts poor prognosis Research Paper

Erratum: Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts Errata

Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Research Paper

Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts Research Paper

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas Research Paper

Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer Research Paper

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Correction

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Correction: TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT Correction

The emergence of trophoblast cell-surface antigen 2 (TROP-2) as a novel cancer target Review

The trophoblast cell surface antigen 2 and miR-125b axis in urothelial bladder cancer Research Paper

TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT Research Paper

Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression Research Paper

Association of tumor TROP2 expression with prognosis varies among lung cancer subtypes Research Paper

Recurrent fusion transcripts in squamous cell carcinomas of the vulva Research Paper

Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer Research Paper

High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells Research Paper

The tumor-inhibitory effectiveness of a novel anti-Trop2 Fab conjugate in pancreatic cancer Research Paper

Trop2 is overexpressed in gastric cancer and predicts poor prognosis Research Paper

Erratum: Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts Errata

Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Research Paper

Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts Research Paper

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC Research Paper